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Viramune (Nevirapine)
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Viramune

Viramune is the brand name for nevirapine, a non-nucleoside reverse transcriptase inhibitor (NNRTI) with activity against Human Immunodeficiency Virus Type 1 (HIV-1). Viramune is structurally a member of the dipyridodiazepinone chemical class of compounds.

Other names for this medication:
Cytocom, Duovir, Emduo, Emtri, Lamostad, Lazid, Nevilast, Nevimune, Nevipan, Nevir, Nevirapine, Neviraprine, Neviretro, Nevirex, Nevivir, Nexvir, Stavex, Trimune, Triomune, Trivir, Virocomb, Virolans, Zidolam

Similar Products:
Aygestin, Minipress, Lioresal, Colcrys, Abhigra, Medimacrol, Corvadil, Keritmon, Amiloretic, Tyfusin,

Also known as: Nevirapine

Description

Viramune XR is an antiviral medicine that prevents human immunodeficiency virus (HIV) from multiplying in your body.

Viramune XR is used to treat HIV, the virus that can cause acquired immunodeficiency syndrome (AIDS). This medicine is not a cure for HIV or AIDS, and should not be used to prevent HIV.

Viramune XR oral solution (liquid) is for use in adults and children as young as 15 days old. This medicine extended-release tablets are for use in adults and children who are at least 6 years old.

Dosage

This section provides information on the proper use of a number of products that contain nevirapine. It may not be specific to Viramune O/S. Please read with care.

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. Also, do not change the dose or stop using this medicine without checking first with your doctor. When your supply of this medicine is running low, contact your doctor or pharmacist ahead of time. Do not allow yourself to run out of this medicine.

This medicine comes with a Medication Guide. Read and follow these instructions carefully before starting nevirapine treatment and each time you refill your prescription. Ask your doctor if you have any questions.

Nevirapine may be taken with or without food, and with water, milk, or soda.

If you or your child are taking the oral liquid, shake it gently before use. Use an oral dosing syringe or dosing cup to measure the right dose. After drinking the medicine, rinse the dosing cup with water and drink the water to make sure you get all of the medicine. If your dose is less than 5 mL (one teaspoonful), use the dosing syringe.

Swallow the extended-release tablet whole. Do not crush, break, or chew it.

Keep taking nevirapine for the full time of treatment, even if you or your child begin to feel better after the first few doses. Your infection may not clear up if you stop using the medicine too soon.

It is important to take nevirapine as part of a combination treatment. Take all other medicines your doctor has prescribed at the right time of the day. This will make your medicines work better.

This medicine works best when there is a constant amount in the blood. To help keep blood levels constant, do not miss any doses. Also, it is best to take the doses at evenly spaced times during the day. For example, if you or your child are taking one dose per day, try to take it at the same time each day. If you are taking two doses per day, the doses should be spaced about 12 hours apart. If you need help planning the best times to take your medicine, check with your doctor.

Do not take more than one dosage form of nevirapine at the same time. Talk to your doctor if you have any questions.

If you stop taking this medicine for more than 7 days, ask your doctor how much to use before you start taking it again. .

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For treatment of HIV infection: For oral dosage form (extended-release tablets): Adults—At first, one 200 milligram (mg) Viramune® immediate-release tablet once a day for the first 14 days. This is followed by one 400 mg Viramune XR® tablet once a day, together with other HIV medicines. Children 6 to 17 years of age with a body surface area of 1.17 square meter (m2) or greater—Dose is based on body size and must be determined by your doctor. The starting dose is usually 150 milligrams (mg) per square meter (m2) of Viramune® oral suspension or tablets for the first 14 days. This is followed by 400 mg of Viramune XR® once a day, together with other HIV medicines. Children younger than 6 years of age with a body surface area of less than 1.17 m2—Use is not recommended. For oral dosage forms (suspension or tablets): Adults—200 milligrams (mg) once a day for 2 weeks, followed by 200 mg 2 times per day, together with other medicines. Children and infants 15 days of age and older—Dose is based on body size and must be determined by your doctor. Infants younger than 15 days of age—Use and dose must be determined by your doctor.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Nevirapine dosage information

Side effects

The most common side effects associated with Viramune are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of nevirapine suspensionor tablets in children. However, safety and efficacy have not been established in infants younger than 15 days of age.

Appropriate studies performed to date have not demonstrated pediatric-specific problems that would limit the usefulness of nevirapine extended-release tablets in children 6 years of age and older with a body surface area of 1.17 square meter (m) or greater. However, use is not recommended in children younger than 6 years of age. Safety and efficacy have not been established in children younger than 6 years of age with a body surface area of less than 1.17 m.

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Tan-1 RT exhibited the most restricted dNTP incorporation efficiency. The possibility has been raised that women who have had large for gestational age infants, while glucose tolerant during pregnancy by conventional testing, may still have a subtle abnormality of carbohydrate metabolism. In the present study, we designed a novel double-layer parallel-plate flow chamber (PPFC) to develop an in vitro ischemia/reperfusion (I/R) injury model and examined the effects of I/R on inflammatory responses in human microvascular endothelial cells (HMEC-1). There were no significant associations with aggregate measures of total customary physical activity. Literature survey, thus far, has shown a decrease in the excretion of urinary tissue kallikrein (TK) in transplant patients with a further reduction of the enzyme during episodes of acute rejection. In contrast to error elimination, this phenomenon of collateral elimination may be a developmental strategy for generating connectional diversity while limiting the amount of information required for the regional specification of the cortex. The up- and down-regulation of cathepsin D expression was further confirmed by enzyme assay. Neck circumference is a good predictive measure of hyperinsulinaemia and raised androgens in obese premenopausal women. Pyelonephritis in slaughter pigs and sows: morphological characterization and aspects of pathogenesis and aetiology. All the ostia were related to the aorta and none to the pulmonary artery.

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We have previously demonstrated that RGD peptides prevent tubular obstruction in ischemic acute renal failure (ARF) suggested that exposed unoccupied integrin receptors represent the target for such therapy. The diagnostic yield of the fine-needle and the screw-needle is equal. Obstructed labour remains a major cause of maternal morbidity and mortality whose complications can be reduced with improved quality of obstetric care. Within a short time of their arrival at the surface and prior to blastoderm formation, nuclei become surrounded by complete cell membranes that block the free uptake of dye (10,000 kDa) from the yolk. Treatment protocols among different published works were reviewed to verify the efficacy of isotretinoin. The negative correlation between the ejection fraction of the gallbladder and mucin concentration of gallbladder bile suggests that chronic inflammation of the gallbladder wall is associated with both an impaired motility of the gallbladder and increased mucin release into gallbladder bile.

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flexneri rose more than five-fold among men, did not change in adult women, and decreased in children. By pioneering dissolution experiments and atomistic simulations, we correlate the dissolution rates-ranging over 4 orders of magnitude-of a selection of silicate glasses and crystals to the number of chemical topological constraints acting between the atoms of the dissolving solid. An acute myeloid leukemia gene, AML1, regulates transcriptional activation and hemopoietic myeloid cell differentiation antagonistically by two alternative spliced forms. What is the role of lipoprotein abnormalities and platelet aggregation defects in cardiovascular disease in chronic dialysis patients?. In contrast with the single-stage approach, a two-stage procedure, starting with ligation of six or fewer lumbar SAs, leads to only a mild drop in SCPP and stimulates vascular remodeling, minimizing the impact of subsequent SA sacrifice on spinal cord function. Image guided brachytherapy (IGBT) for locally advanced cervical cancer allows dose escalation to the high-risk clinical target volume (HRCTV) while sparing organs at risk (OAR). The most important of these clinical factors is stage, volume of residual tumor remaining after surgical resection, performance status and age, interval between end of primary therapy and beginning of recurrence, drug resistance. To assess stress manipulation, autonomic and endocrine, as well as subjective, measurements were acquired throughout the experiment. should be included in the differential diagnosis of head and neck abscesses in predisposed individuals and treated accordingly. Non-Caucasian ethnicity is associated with lower rates of new ADM use.

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Noribogaine was also associated with emesis and partial anorexia. Further research with a more high-risk sample is needed to validate the clinical utility of the identified clusters. The bibliographic search was carried out in Pubmed/Medline, Scopus and Cochrane Library and included articles taking a sample of children between 0 and 18 years of age diagnosed with the abovementioned disorders and including at least one of the following oral hygiene conditions - oral hygiene, dental caries, malocclusion, oral habits, dental trauma, and gingival-periodontal status - comparing them with a healthy population. Macrophage form, function, and phenotype in mycobacterial infection: lessons from tuberculosis and other diseases. Also the large subunits I and II (core proteins) and band VI appear to be conserved in structure, while subunits VII and VIIa show a most remarkable structural variation in the various complexes. We compared two different types of RTP power modulation techniques, angiomode (AM) and high-resolution grayscale (HR), with 99mTc-tetrofosmin single-photon emission computed tomography (SPECT) for the detection of myocardial ischemia. The effect of placental removal method on the incidence of postcesarean infections. It occurs most commonly in women at times of low sex hormone output.

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Stimulus-responsive biomolecules are attractive targets to understand biomolecule behaviour as well as to explore their therapeutic and diagnostic applications. Analysis of phosphorylation of pRB and its regulatory proteins in breast cancer. Professional journals, government reports, culturally sensitive materials, and field experience. All patients had moderately to extremely high serum ferritin levels and LDH levels. The kdp system of Clostridium acetobutylicum: cloning, sequencing, and transcriptional regulation in response to potassium concentration. Evaluate the diagnostic and therapeutic utility, safeness, efficacy and complications of double-balloon enteroscopy (DBE). This test system, presented as the Nijmegen mouse embryo assay (NMEA), can be used to detect embryo-toxic materials in daily IVF practice, and this report may provide a starting point for standardization.

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Southeast Missouri Hospital, a community hospital located in a rural part of the state, provides a full range of coordinated stroke rehabilitation therapies, both inpatient and outpatient. For adults in southern Germany, and for the rest of the population in Germany, the figure is considerably lower. Nine VPS procedures were performed in eight hydrocephalic patients between 1988 and 2000. To determine level, variability and functional annotation of gene expression of the human retinal pigment epithelium (RPE), the key tissue involved in retinal diseases like age-related macular degeneration and retinitis pigmentosa. Repeat expansion detection (RED) technique was used to measure genomic CAG/CTG repeat size, and PCR for CAG repeat size at the ERDA-1 and CTG 18.1 loci. We conclude that caspase-1 modulates apoptosis of both peripheral blood and inflammatory neutrophils, but is not essential for IL-1beta production in the lung. Cell competition is a quality asthma mercury drug price ventolin inhaler price philippines control mechanism that eliminates unfit cells. When ventilatory support is withdrawn in an intensive care unit (ICU), the place of death for most patients is the hospital.

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A randomized, double-blinded, placebo-controlled crossover study of 4 weeks of antioxidant supplementation (BiO-Antioxidant 2.1 (400 mg vitamin C and 180 mg vitamin E d(-1)) and BiO-Quinon Q10 (200 mg d(-1) was performed. Synthesis, biodistribution and imaging properties of indium-111-DTPA-paclitaxel in mice bearing mammary tumors. We present here an adaptive optics implementation that incorporates two adaptive optic elements to enable correction in all beam paths, allowing performance improvement in thick tissue samples. Hormonal level and target-cell innervation in the functional development of a beta-adrenoreceptor-adenylate cyclase membrane complex. Significance of growth hormone-releasing hormone receptor mRNA in non-neoplastic pituitary and pituitary adenomas: a study by RT-PCR and in situ hybridization. Alterations in brain tumor DNA detected by a fingerprinting probe. The efficacy of therapy was assessed by evaluating clinical symptoms, laboratory data, and cholangiograms. UK-14,304 (1.0 nmol kg-1 min-1), a mixed alpha 2-adrenoceptor/imidazoline receptor agonist with selectivity for the alpha 2a-subtype increased only osmolar clearance. In general, the immobilization reduced the activity of the enzyme, but increased its thermal stability. In this paper, we investigate capillary interactions between magnetic Janus particles adsorbed at fluid-fluid interfaces.

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To determine what effect, if any, intraoperative blood loss has on serum antibiotic levels, and to determine if adjustment of the dose or dose interval is appropriate in operative cases of significant blood loss. Notably, matrix metalloproteinase 12 (Mmp12) was highly ranked in all analyses and was therefore chosen for further investigation. This method has evolved as a highly sensitive, rapid, simple and effective modality for screening and as well as accurate preoperative diagnosis of ovarian lesions. UTSA-74: A MOF-74 Isomer with Two Accessible Binding Sites per Metal Center for Highly Selective Gas Separation. A lentivirus-based VEGF-C siRNA vector was infected into breast cancer cells and a xenograft model. Three new diseases listed for Japanese research on their treatment. Perception of iron deficiency from oral mucosa alterations that show a high prevalence of Candida infection. No significant repression was noted by TJ-14 even at 1000 mg/kg, p.o. Ultrasonographic detection of metastatic axillary lymph nodes in breast cancer.

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