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Unigyl (Metronidazole)
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Unigyl

Unigyl is a medicine used to treat different types of bacterial and parasitic infections, including those that affect the skin, vagina, blood, heart, bone, stomach, liver, joints, nervous system, respiratory tract, and other areas of the body.

Other names for this medication:
Aldezole, Anegyn, Bemetrazole, Biatron, Birodogyl, Clont, Collazole, Colpofilin, Deprocid, Diazole, Etronil, Farnat, Flazole, Fortagyl, Gnostol, Gynoplix, Kilpro, Klont, Mebadiol, Mecozol, Medamet, Metrodal, Metroderme, Metrolotion, Metronid, Metronidazol, Metrosil, Metryl, Molazol, Mtronidazole, Negazole, Nipazol, Noritate, Norzol, Patryl, Rhodogil, Rosaced, Rosalox, Rosiced, Rozagel, Stomorgyl, Triconex, Venogyl

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Also known as: Metronidazole

Description

Metronidazole is used to treat bacterial infections in different areas of the body. The extended-release tablets are used to treat women with vaginal infections (bacterial vaginosis).

Metronidazole belongs to the class of medicines known as antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.

This medicine is available only with your doctor's prescription.

Dosage

In the Female. One-day treatment – two grams of Unigyl, given either as a single dose or in two divided doses of one gram each, given in the same day. Seven-day course of treatment – 250 mg three times daily for seven consecutive days. There is some indication from controlled comparative studies that cure rates as determined by vaginal smears and signs and symptoms, may be higher after a seven-day course of treatment than after a one-day treatment regimen.

The dosage regimen should be individualized. Single-dose treatment can assure compliance, especially if administered under supervision, in those patients who cannot be relied on to continue the seven-day regimen. A seven-day course of treatment may minimize reinfection by protecting the patient long enough for the sexual contacts to obtain appropriate treatment. Further, some patients may tolerate one treatment regimen better than the other.

Pregnant patients should not be treated during the first trimester In pregnant patients for whom alternative treatment has been inadequate, the one-day course of therapy should not be used, as it results in higher serum levels which can reach the fetal circulation.

When repeat courses of the drug are required, it is recommended that an interval of four to six weeks elapse between courses and that the presence of the trichomonad be reconfirmed by appropriate laboratory measures. Total and differential leukocyte counts should be made before and after re-treatment.

Overdose

If you overdose Generic Unigyl and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Generic Unigyl overdosage: dizziness, seizures, torpor, retching, nausea, lack of balance, problems with coordination, tingling.

Storage

Keep this medication in the container it came in, tightly closed, and out of reach of children. Store it at room temperature and away from excess heat and moisture (not in the bathroom). Throw away any medication that is outdated or no longer needed. Talk to your pharmacist about the proper disposal of your medication.

Side effects

The most common side effects associated with Unigyl are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Meningitis Not Caused by an Infection, Decreased Neutrophils a Type of White Blood Cell, Habit of Drinking Too Much Alcohol, Alcohol Intoxication, Lower Seizure Threshold, Disorder of the Brain, peripheral neuropathy, prolonged QT interval on EKG, Severe Liver Disease, seizures, Cockayne syndrome

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Two additional fatty acid ethanolamides that bind to the cannabinoid receptor, homo-gamma-linolenylethanolamide and docostetraenylethanolamide, have been identified in the brain. In therapeutic methods, little improvement has been observed for last decade since introduction of bone marrow transplantation. Qualitative methods in medical research--preconditions, potentials and limitations. The results support the hypothesis that the equine embryo interacts with the oviduct, affecting the maternal secretion pattern of proteins involved in pregnancy-related pathways. The benefits of exercise are well established but the impact of exercise on the older adult is not as clearly defined. Furthermore, Tbx3 expression was found to be suppressed by AFLL when the expression of tumor suppressor genes p14 and p53 were activated.

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Protein kinase A (PKA) phosphorylates inhibitor-1, mediating binding to PP1. Temperature and solvent effects in the solubility of some pharmaceutical compounds: Measurements and modeling. Specifically, tensile and torsional shear strengths were measured for zinc phosphate, polycarboxylate, glass-ionomer, silicophosphate, and AH-26 cements. Direct analysis of the major human seminal prostaglandins by thermospray high-performance liquid chromatography-mass spectrometry. The heart rate and corneal-palpebral reflex were evaluated at the beginning of sedation, during the surgical procedures, and at the end of those procedures. In particular, evidence is cited that supports a beneficial effect of the host response to non-small-cell lung cancer and the association of a poor prognosis in established breast cancer caused by a heightened immune response to the tumor. Using gene specific probes derived from this sequence, RNase protection assays, reverse transcription-polymerase chain reaction (RT-PCR) assays and in-situ hybridization, showed relaxin gene expression within the ovary in theca cells and corpora lutea in the oestrous cycle, increasing in early pregnancy. Both groups exhibited comparatively decreased posterior tibial slope.

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Rapid diagnosis of methicillin-resistant Staphylococcus aureus bacteremia by nested polymerase chain reaction. To investigate predictors of change in the sense of competence of primary caregivers and continuity in home care for dementia patients. Such decomposition of the overall response is demonstrated by mapping the nonlinear response of intersubband transitions in GaAs/AlGaAs multiple quantum wells. Thauera aromatica T1 was isolated aceon cost for its ability to use toluene as a sole carbon source under denitrifying conditions. Knowledge of the factors that inform the career choice of medical students may help plan the workforce for medical specialties. An experimental form of mesangial proliferative GN can be induced in rats by either polyclonal or monoclonal antibodies against Thy-1.1, a glycoprotein present on the surface of MC. coli topoisomerase III (Topo III) to fully catenate dsDNA molecules.

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Placement in an EE after TBI enhanced spatial memory performance in male but not female rats. Breast-fed infants are susceptible to human cytomegalovirus infection from breast milk. CCN family 2/connective tissue growth factor (CCN2/CTGF) promotes osteoclastogenesis via induction of and interaction with dendritic cell-specific transmembrane protein (DC-STAMP). Role of striatal dopamine D1 receptors (D1Rs) in methamphetamine (Meth) taking and seeking is recognized from contingent Meth self-administration studies. Using computer-aided design and drafting software, we obtained a first simplified 3D model of CECs. Expression of p21 was noted in moderately to well-differentiated stomach cancer, intestinal metaplasia, and atypical hyperplasia. Genetic Lineage and Reassortment of Influenza C Viruses Circulating between 1947 and 2014.

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Analogous to optical flow, where an image is aligned to its temporally adjacent frame, we propose SIFT flow, a method to align an image to its nearest neighbors in a large image corpus containing a variety of scenes. Early diagnosis and management are essential to prevent sequelae and possible transmission. Here we establish the existence of similarly linked glycoproteins in the yeast Saccharomyces cerevisiae. We conclude that 6-NBDG, used at low concentrations, permeates into astrocytes chiefly through GLUT1, and advise that the exofacial GLUT1 inhibitor 4,6-ethylidine-D-glucose be used, instead of glucose, as the tool of choice to confirm the specificity of 6-NBDG uptake. Anesthesia was maintained with propofol, rocuronium and remifentanil in perfusion during the intervention, which was uneventful. Measurements of cerebrospinal fluid (CSF) purine levels and spinal cord glutamate uptake were performed. To determine with the highest level of evidence the efficacy of pelvic floor rehabilitation in the treatment of stress urinary incontinence in women. The effects of CYP3A4 induction and inhibition on the pharmacokinetics of alisporivir in humans.

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