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Thorazine (Chlorpromazine)

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Thorazine is a phenothiazine (FEEN-oh-THYE-a-zeen) that is used to treat psychotic disorders such as schizophrenia or manic-depression in adults. Thorazine is used in adults to treat nausea and vomiting, anxiety before surgery, chronic hiccups, acute intermittent porphyria, and symptoms of tetanus.

Other names for this medication:
Chlorpromazine, Clozine, Megatil, Serectil

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Adipex, Anafranil, Ilosone, Cipro, Suprax, Nevimune, Reminyl, Kaftrim, Dizeral, Corentel, Gestmate, Uniretic, Lozitan, Rotramin, Salyco,

Also known as: Chlorpromazine


Generic Thorazine is an effective preparation developed by medical scientists to treat certain mental or mood disorders (eg, schizophrenia), the manic phase of manic-depressive disorder and severe behavioral problems in children. Generic Thorazine is also used to control nausea and vomiting, nervousness before surgery, and hiccups that will not go away. Generic Thorazine can be used to treat episodes of porphyria and in combination with other medicines to treat tetanus. Generic Thorazine is an anti-psychotic medication in a group of drugs called phenothiazines. Generic Thorazine works by changing the actions of chemicals in your brain. Generic Thorazine may also be used for other purposes. Generic name of Generic Thorazine is Chlorpromazine. Brand name of Generic Thorazine is Thorazine.


Take Generic Thorazine by mouth with a glass of water. Take Generic Thorazine at regular intervals. Do not take it more often than directed. Do not take Generic Thorazine in large amounts. If you want to achieve most effective results do not stop using Generic Thorazine suddenly.


If you overdose Generic Mellaril and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Generic Thorazine overdose: dry mouth, constipation, bloating or stomach cramps, feeling restless or agitated, fever, seizure, muscle stiffness, jerky muscle movements, changes in heart rate, extreme drowsiness, and fainting.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Thorazine are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Generic Thorazine if you are allergic to Generic Thorazine components, or other phenothiazines such as fluphenazine (Permitil), perphenazine (Trilafon), prochlorperazine (Compazine, Compro), promethazine (Adgan, Pentazine, Phenergan), thioridazine (Mellaril), or trifluoperazine (Stelazine). Do not take Generic Thorazine if you're pregnant or you plan to have a baby, or you are a nursing mother. Do not use Generic Thorazine in psychotic conditions related to dementia. Do not use Generic Thorazine if you have brain damage, bone marrow depression, or are also using large amounts of alcohol or medicines that make you sleepy. Be very careful with Generic Thorazine if you have liver or kidney disease, heart disease or high blood pressure, glaucoma, severe breathing problems, past or present breast cancer, low levels of calcium in your blood, adrenal gland tumor, enlarged prostate or urination problems, a history of seizures, Parkinson's disease. Do not take Generic Thorazine together with: atropine (Atreza, Sal-Tropine); lithium (Eskalith, Lithobid); phenytoin (Dilantin); an antibiotic; birth control pills or hormone replacement estrogens; blood pressure medication; a blood thinner such as warfarin (Coumadin, Jantoven); certain asthma medications or bronchodilators; incontinence medications; insulin or diabetes medications you take by mouth; medication for nausea, vomiting, or motion sickness; medications to treat or prevent malaria; medications used for general anesthesia; medicines used to prevent organ transplant rejection; numbing medicine such as lidocaine or Novocain; a stimulant or ADHD medication; ulcer or irritable bowel medications; or medicines to treat Parkinson's disease, restless leg syndrome, or pituitary gland tumor (prolactinoma). Avoid temperature extremes, such as saunas, hot tubs, or very hot or cold baths or showers. Dress warmly in cold weather. Avoid using other medicines that make you sleepy while using Generic Thorazine. Be careful if you drive or do anything that requires you to be awake and alert while using Generic Thorazine. Avoid exposure to sunlight or tanning beds. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors. Avoid drinking alcohol. It can be dangerous to stop Generic Thorazine taking suddenly.

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Avalanche of stimulated forward scattering in high harmonic generation. Our data base has 250 possible fields per event with multiple events per patient. To assess the comparable efficacy and adverse effect profile of two extended-release preparations of nifedipine--gastrointestinal therapeutic system (GITS) and coat-core (CC)--in patients with mild-to-moderate hypertension. Midazolam is used for sedation of intensive care unit (ICU) patients and it is extensively metabolised by CYP3A4 enzymes. Focal hand dystonia is a challenging movement disorder to rehabilitate in musicians and writers. However, experiments using MDA-MB-231 cells, a standard in vitro breast cancer model, produced inconsistent results regarding effectiveness of metformin as a direct anti-cancer agent.

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Tumor growth led to progressive proptosis and loss of light perception. The avoidance of clinical inertia in pursuing subtle changes in graft function is critical. Regioselective synthesis of 3,4-disubstituted isocoumarins through the Pd-catalyzed annulation of 2-iodoaromatic acids with ynamides. We conclude that, clinically, edrophonium and ambenonium are safer drugs than pyridostigmine and neostigmine, at least as regards muscarinic side-effects, including bradycardia. Marijuana is associated with disturbance in similar brain systems, and thus it is hypothesized that the added neural strain of marijuana can exhaust neural resources, resulting in pronounced memory impairment. Proteasomes are protein degradation machines that exist in cells as heterogeneous and dynamic populations. Main results, problems encountered and future plans are discussed. Statistical analyses included multivariate regression, calculated odds ratios, and posttest probabilities. Rapid changes in central beta-adrenergic receptors after chronic intravenous infusion of antidepressants. The study evaluated a prospective ongoing trial of women with an 8-week gestation or less wanting an abortion.

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The objective of this study was to examine the effects of a cognitive adjustment program on parental attitudes toward child rearing and the potential for this abuse. Recent studies have suggested that allelic variations in the adrenergic receptor beta2 gene, the interleukin (IL)-4 gene and its receptor gene are closely associated with immune diseases. In this study, the authors investigated potential explanations for sparse lexical-semantic representations in children with specific language impairment (SLI) and typically developing peers. Endocytosis has been suggested to be crucial for the process in both cases. These cells showed single nuclei, and their cytoplasm contained numerous mitochondria, vacuoles, granules, and coated vesicles. Deletion analysis localized the N-terminal PDZ-binding site in Kv1.5 to the T1 region of the channel. We have demonstrated earlier that the TcR/CD3-induced activation of Fyn results in tyrosine phosphorylation of several Fyn-associated proteins, including a protein of 116 kDa. The degree to which the MUNE decreased correlated with the part of the JSS showing the upper extremity weakness. We conclude that guided wave measurements may offer an enhanced approach to the ultrasonic characterization of long bones.

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The amount of bowing in the resting position and the glottal gap area and vibratory amplitude during phonation were measured from digitized videostroboscopic images. The nanoscale heat management by Cu2Te nanoclusters in superionic conductors opens up an avenue for thermoelectric materials research. The effects of ethnic discrimination and socioeconomic status on endothelin-1 among blacks and whites. It is characterized by an in-frame tandem duplication of exon 3 that encodes the second zinc finger of the AR DNA-binding domain. Frailty results because not everyone of the same age has the same number of deficits. Sequential Therapy versus Triple Therapy for the First Line Treatment of Helicobacter pylori in Korea: A Nationwide Randomized Trial. In necropsy, in addition to peritonitis with massive adhesions, a cauliflower-shaped, irregular, tough, greyish-white uterine tumour was seen. However, in the current study in couples in which the male had a history of testicular torsion the pregnancy rate and the interval to pregnancy were within the accepted range of the general population. We examined the effects of fetal and infant growth patterns on cardiovascular outcomes in children.

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The negative association between anterior volume and years of heavy drinking was driven primarily by alcoholic men. Pharmacokinetics of meloxicam in red-eared slider turtles (Trachemys scripta elegans) after single intravenous and intramuscular injections. In the normal healthy mammary gland, macrophages predominate and act as sentinels to invading mastitis-causing pathogens. Direction discrimination thresholds for maximum motion displacement (Dmax) are not fixed but are stimulus dependent. In any event, the authors stress the need to avoid uncertainty and delay in view of the youthful age of most of the subjects affected and the potential danger of the complications of this apparently banal disease. The pathologic findings of our case suggest possible direct rhabdomyogenic differentiation of melanoma cells. In Stage IIIA disease, R1-BRM showed similar overall survival rate to that for R0-BRM, although the number of patients was too small to draw definitive conclusions thereon.

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Binding experiment KD values and physiologically active GABA concentrations: an only apparent contradiction?. Previous studies have indicated that the secondary structure of the rplJ leader region is important for efficient translation and feedback regulation. It would be discussed in some high-risk groups of patients with breast and colorectal cancers. In vitro production of endothelin-1 and prostacyclin by cultured endothelial cells in the presence of polymers. Up-regulation of Eph tyrosine kinase receptors after excitotoxic injury in adult hippocampus. This article is a review of the source of dendritic cells, loading antigen, immunotherapy pathway, clinical application, choice of patients, and so on.

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Ninety-two equine herpesvirus type 1 isolates were recovered from aborted, stillborn, or neonatal foals from Ontario, Canada, from 1986 to 1992. A Person-centered Approach to Studying the Linkages among Parent-Child Differences in Cultural Orientation, Supportive Parenting, and Adolescent Depressive Symptoms in Chinese American Families. However, in this case, no bleeding tendency was observed and the abnormality was dependent on the presence of ethylenediamine tetra acetic acid (EDTA) and did not occur in a nonanticoagulant, trisodium citrate dihydrate and heparin. They suggest that these seizures are mediated through an NMDA receptor activation and NO production, without involvement of inhibition of glutamine synthetase. The amount of radiation used can be reduced by careful attention to imaging technique. We included in our study all consecutive patients treated for primary infected aortic aneurysm at our facility between 1995 and 2011. Nevertheless both technical improvements and further clinical experience is necessary.

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MEKK2, a closely related homologue of MEKK3, also activated MKK7 and MKK6 in COS-7 cells. Thus, the role of the ninth heptad in heterodimerization differs on direct repeat, palindromic, and inverted palindromic response elements, suggesting that the protein-protein interactions differ on each of these elements. The missense mutation in the SLD GHR gene may thus affect targeting of GHRs to hepatic plasma membranes. To explore the idiopathic ASD-associated copy number variations (CNVs), we conducted case-control study using whole-genome copy number analysis. Pediatric hepatocellular carcinoma in a developing country: Is the etiology changing?.

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Percutaneous aortic valve insertion is an emerging treatment option for selected patients with severe aortic stenosis and may be done from a transfemoral or transapical approach. In 14 patients receiving chronic amiodarone therapy the appearance of multilamellar inclusion bodies in peripheral blood neutrophils was related to both plasma concentrations of amiodarone and its desethyl metabolite and unwanted effects of the drug. Evaluation of HIV vaccine candidates in nonhuman primates (NHPs) is a critical step toward developing a successful vaccine to control the HIV pandemic. Stereotactic light-ion radiosurgery resulted in better angiographically defined obliteration rates, less white-matter necrosis, lower complication rates, and more favorable clinical outcomes. A similar percentage of cultured cells also were reactive with monoclonal antibodies to the EBV/C3d receptor of B lymphocytes. Comparable clinical characteristics including incidence of distant and lymphatic metastases, tumor stage and prognosis is presented between male and female as well as between children and adults.

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is thorazine a controlled drug 2017-04-02

On the basis of our observation that the defect of the PDL was replaced rather than restored, we conclude that the rabbit model has disadvantages and is less suitable for studies of regeneration of PDL. The resultant edema causes refractory hypoxemia due to intrapulmonary shunting and loss of lung compliance. Another 10 cats had general anesthesia, ovariohysterectomy, and postoperative administration of 0.3 mg butorphanol/kg. Generalized dilation of the visceral microvasculature by peritoneal dialysis solutions. We discuss the implications of our results with regards to the structure of the rifampicin binding site. Early results of a prospective study that compared surgical revascularization and thrombolysis for lower extremity arterial and graft occlusions have been published. Statins induce regression of carotid artery stenosis: Fact or fiction?. Diabetic and control preparations developed equal peak tension at each driving frequency upon the application of paired- what does remeron 30 mg look like pulse stimulation with fixed interpulse interval.

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Pharmacological Reprogramming of Fibroblasts into Neural Stem Cells by Signaling-Directed Transcriptional Activation. The disease is most common in males over the age 40 years with sings and symptoms of neoplastic disease with or without a palpable abdominal mass, abdominal pain and ascites. Epidermal growth factor and sex steroids dynamically regulate a marker of endometrial receptivity in Ishikawa cells. T(sk) is largely under control of peripheral vascular tone, which is also sensitive to most experimental manipulations such as handling and restraint. Synergy and antagonism as measured by the combination index were determined for each combination how to wean off prilosec 40 mg .

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These results indicate that, in addition to mean performance levels, variability of task performance may provide a valuable source of evidence regarding the actual cause of performance limitations or deficits in conflict situations. For these acyl-CoAs, substrate inhibition was observed when concentrations approached their critical micellar concentrations. Because edges of the rent were smooth and fibrous, which suggested the defect was chronic, the abdomen was closed without repairing the rent. These techniques which include MR spectroscopy (MRS) and spectroscopic imaging (SI), are based on classical nuclear magnetic resonance (NMR) spectroscopy and are capable of providing biochemical information in vivo. The proportion of patients adhering to advice and percent advice taken were calculated. Particularly, the reconstruct-ability of electromechanic feedback mechanisms was examined. Using in vitro systems and gnotobiotic mouse colonization models, we find that extracellular digestion of inulin increases the fitness of B. This study was designed to investigate the effects of 4-CmC in vivo and in vitro in the same animals. We show that the superficial venous changes seen in SCN4 patients can develop into varicose veins and venous ulcers in adulthood.

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Pancreatic cancer can involve activation of Ki-Ras, overexpression of Myc or ErbB-2 does generic lexapro make you tired , and mutational inactivation of functional p53. The count-based approach generally provides a wider phase distribution and subsequently greater SD and BW estimates compared with the geometrical algorithm. Lipid Emulsion in Local Anesthetic Toxicity: Long-winded, Rude, and Right. Recently, spherical beads entrapping quorum quenching (QQ) bacteria have been reported as effective moving QQ-media for biofouling control in MBRs for wastewater treatment owing to their combined effects of biological (i.e., quorum quenching) and physical washing. Spin trapping-EPR was able to detect radical adducts in five of the seven reperfused skin flaps. However, there is an urgent need to extend the current CellML metadata standard to provide biological and biophysical annotation of the models in order to facilitate model sharing, automated model reduction and connection to biological databases. Liver biopsy: effects of biopsy needle caliber on bleeding and tissue recovery.

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Thirty-eight females with patellofemoral pain, and 33 female pain-free controls. Review can you buy liquid imodium over the counter : Joint lavage does not reduce pain or improve function in knee osteoarthritis. A computed tomographic scan of the thorax confirmed an -extensive mediastinal mass. Alterations in spinal fluid drainage in infants with hydrocephalus. Concurrent US and MRI pairs are acquired during a relatively brief offine learning phase involving the US transducer and MR scanner. Stress mediated changes in hypothalamic corticotropin releasing factor-like immunoreactivity.

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The results of the present study suggest that PAN metastasis may occur as a consequence of PLN metastasis or the two may occur simultaneously as PLN metastasis and also that careful examination of PAN metastasis is necessary to determine the prognosis. The aim of this study was to investigate the mechanism of apoptosis induced by c-myc(cellular avian myelocytoma virus) gene in oral squamous cell carcinoma cell line Tca8113. Compared with patients initiating sitagliptin treatment, patients initiating saxagliptin treatment reported lower overall and medical charges and lower overall and diabetes-related hospitalization rates. Aneurysm of the hepatic artery demonstrated roentgenographically. The measurement of these small molecules in brain tissue and extracellular fluid has been used to develop effective treatment strategies for neuropsychiatric and neurodegenerative diseases and for the diagnosis of such pathologies. In patients in whom the initially elevated levels of aldosterone and AC failed to decline or in whom there was an even greater increase in AC concentrations, the therapeutic effect of EAP procedures was insignificant and short-lived. Biliopancreatic diversion for treatment of morbid obesity: experience in 180 consecutive cases.

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Perhaps for this reason they are seldom recognized clinically, although histopathological studies are increasingly disclosing the gonadotrope nature of many pituitary tumors. However, combination with new classes such as integrase inhibitors (currently in phase I trials) and CCR5 antagonists (no paediatric data yet) will probably be necessary to gain maximal long-term benefits. This is a brief review of the rapidly expanding, but still incomplete, knowledge of how T cells, through both contact-dependent and cytokine signals, regulate macrophage function during inflammatory disease. In osteoporosis with low bone turnover, fluoride in long-term therapy is the preferred medication. Induction of the aromatic hydrocarbon receptor by trans-4-acetylaminostilbene in rat liver. Clinical and genetic features of the isolated congenital skin defects are also reviewed. Erythromycin might have therapeutic value in patients with intestinal motility dysfunction in acute dysautonomia. Butyrate kinase is rapidly inactivated at 50 degrees C in the absence of a fatty acid substrate.

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Have equipment that is compatible with the skier both from the standpoint of size and expertise. Weekly injections of Hylan G-F 20 starting 1 week after surgery delayed cartilage degeneration after meniscectomy in a rat model. The basic objective of the program is to clarify the role of the genetic apparatus in the adaptation of living systems to microgravity and, consequently, to determine the role of gravity in the evolution of life on the Earth. The mechanism of demyelination of the peripheral nerves may be similar to that described in patients with IgM kappa monoclonal gammopathies. Cross-cultural adaptation of the Cyberchondria Severity Scale for Brazilian Portuguese. Research of the spatial-temporal gait parameters and pressure characteristic in spastic diplegia children. Plinth padding and measures of posteroanterior lumbar stiffness.

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Cells resembling lymphocytes or monocytes had been described in the epididymis, but previous studies differed as to their nature and immunologic significance. This study was undertaken to investigate the expression of TLRs in peripheral blood-mononuclear cells (PBMCs) of AA patients and to determine whether TLR-mediated inflammatory signals are important for the perspective of AA management. A disrupted circadian cycle, involving hypothermia, is proposed as the mechanism underlying the demise of animals in the activity-stress paradigm. Factors influencing this choice were studied using a cross-sectional study with children (6 to 8 years old) living in Coimbra. A sorghum cDNA clone was isolated by differential screening of a cDNA library prepared from mesocotyls (cultivar DK18) inoculated with fungal pathogenes. Induction of asynchronous replication of polyoma DNA in rat cells by ultraviolet irradiation and the effects of various inhibitors. However, to achieve sustained suppression of leukocyte elastase, alpha1PI must be given frequently and in large amounts, thus limiting its clinical use. To evaluate the reactivity of antitumor agents in a nucleosome architecture, we conducted in vitro studies to assess the alkylation level of duocarmycin B2 on nucleosomes with core and linker DNA using sequencing gel electrophoresis.

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This study assessed the movement behaviour of patients with eating disorders and inflammatory bowel disease. Our experience with 9 successful extractions and implantations is recorded. Oncoproteomics is playing an increasingly important role in the diagnosis and management of cancer as well as in the development of personalized treatment of cancer. Synthesis of a new tetradentate beta-diketonate-europium chelate and its application for time-resolved fluorimetry of albumin. Unveiling the basis of alkaline stability of an evolved versatile peroxidase.

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Inflammatory myofibroblastic pseudotumour of the liver in association with gall stones - a rare case report and brief review. The actual opportunistic screening approach presents important deficiencies with displaced priorities in test performance and a low proportion of individuals undergoing recommended tests. In the present study, we observed that IGF-1 was able to induce ZNF143 expression in HCT116 human colon cancer cells and that wortmannin, an inhibitor of phosphatidylinositide 3- kinase (PI3-kinase), inhibited this induction, as did diphenyleneiodonium (DPI), an NADPH oxidase inhibitor, and monodansylcardavarine (MDC), a receptor internalization inhibitor. Caesarean sections at E18.5 revealed that half of the compound heterozygotes died soon after birth, and the majority of the dead individuals exhibited VSD. Spectrum of different types of hypophysitis: a clinicopathologic study of hypophysitis in 31 cases. The aim of this study was to investigate the frequency and types of PTC genetic rearrangements in papillary carcinoma in a population of Hong Kong Chinese. This report describes the case of a patient who presented with presumed cocaine-induced myocardial infarct. Seat belt use can decrease the mortality rate associated with road traffic accidents (RTA). In order to improve the molecular basis for the use of bivalve cholinesterases as a reliable biomarker for aquatic pollution, the polymorphism and characterization of these enzymes in Mytilus edulis, Mytilus galloprovincialis and Corbicula fluminea were investigated. Options to preserve fertility were positively viewed but the actual use may be limited by concerns about safety.

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