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Rical (Calcitriol)
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Rical

Rical is a hydroxycalciol that is calcidiol in which the pro-S hydrogen of calcidiol is replaced by a hydroxy group. It is the active form of vitamin D3, produced fom calciol via hydoxylation in the liver to form calcidiol, which is subsequently oxidised in the kidney to give Rical.

Other names for this medication:
Actical, Admax, Alfacal, Alfacalcirol, Alfarich, Arcium, Bonestat, Bonetuf, Calbec, Calbory, Calcigra, Calcimet, Calcor, Calday, Caldikind, Caldix, Calfa, Calgel, Calosto, Calotec, Caltin, Caltop, Carcal, Cholical, Citroj, Coecoral, Devita, Dmcal, Estovon, Ikmag, Minroset, Osteobel, Ostriol, Refirm, Riecal, Rockbon, Sorvate, Statbone, Tobalt, Trolec

Similar Products:
Remeron, Omnicef, Imovane, Thorazine, Theolair, Ovral, Hytrin, Clomid, Kemadrin, Coumadin, Metlong, Dexphen, Mobic, Femphascyl, Piotop, Omelam, Carbasma, Pedilice, Armix,

Also known as: Calcitriol

Description

Generic Rical is a synthetic vitamin D analog which is active in the regulation of the absorption of calcium from the gastrointestinal tract and its utilization in the body. The two known sites of action of Generic Rical are intestine and bone. Generic Rical receptor-binding protein appears to exist in the mucosa of human intestine. Additional evidence suggests that Generic Rical may also act on the kidney and the parathyroid glands. Generic Rical is the most active known form of vitamin D3 in stimulating intestinal calcium transport. In acutely uremic rats Generic Rical has been shown to stimulate intestinal calcium absorption. The kidneys of uremic patients cannot adequately synthesize Generic Rical, the active hormone formed from precursor vitamin D. Resultant hypocalcemia and secondary hyperparathyroidism are a major cause of the metabolic bone disease of renal failure. However, other bone-toxic substances which accumulate in uremia (eg, aluminum) may also contribute. The beneficial effect of Generic Rical in renal osteodystrophy appears to result from correction of hypocalcemia and secondary hyperparathyroidism. It is uncertain whether Generic Rical produces other independent beneficial effects. Rical is also known as Calcitriol. Generic Rical treatment is not associated with an accelerated rate of renal function deterioration. No radiographic evidence of extraskeletal calcification has been found in predialysis patients following treatment. The duration of pharmacologic activity of a single dose of calcitriol is about 3 to 5 days. Generic name of Generic Rical is Calcitriol. Brand name of Generic Rical is Rical.

Dosage

Generic Rical is available in capsules (0.25 mcg) and liquid form. Capsules must be swallowed whole. Do not crush or chew them. If you are prescribed the liquid form, use as directed. Follow dosing instructions closely. Do not take this medication with mineral oil or magnesium containing antacids which may reduce its effects. Foods rich in vitamin D include: fortified dairy products, eggs, sardines, cod liver oil, chicken livers and fresh-water fish. Vitamin D is also obtained from periodic exposure to the sun. It is important to maintain a well-balanced diet while taking this medication. Calcium supplements may be recommended in addition to this medication. If you want to achieve most effective results do not stop taking Generic Rical suddenly.

Overdose

If you overdose Generic Rical and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Rical are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

If you are taking a dietary supplement without a prescription, carefully read and follow any precautions on the label. For these supplements, the following should be considered:

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Two contrasting soil profiles (sand and loam) from cropping land of southwest Western Australia were exposed to artificial rain in packed boxes and field runoff plots to examine P forms and fluxes in runoff, throughflow, leachate and soil solution after three P rates of application (equivalent to 0, 20 and 40kg P/ha). Mitotic chromosome condensation is an essential cellular function ensuring proper compaction and segregation of sister chromatids during cell division. We studied health-related selection and consequences of an organizational downsizing among 886 municipal employees. Furthermore, in copper-starved yeast, the response of the Rad53 pathway to MMS is compromised due to a loss of Sod1 activity, consistent with the model that yeast imports copper to ensure Sod1 activity and Rad53 signaling. It is demonstrated that nanocrystal films encapsulated into semiconductor matrices exhibit a lower probability of charge scattering than that of nanocrystal solids cross-linked with either 3-mercaptopropionic acid or 1,2-ethanedithiol molecular linkers. Moreover, learning and memory impairments worsened at 6 and 12 months of age, when animals failed to acquire the fixed platform location in the water maze and showed passive avoidance deficits.

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