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Premelle (Medroxyprogesterone)

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Premelle is a synthetic progestin that replicates the effect of a natural female hormone called progesterone. It slows the growth of the lining of the womb before menstruation. It reduces the bleeding during menstruation.

Other names for this medication:
Curretab, Deviry, Empeea, Farlutal, Litmus, Medrigest, Medroxyprogesterone, Medtet, Megest, Megestone, Meprate, Orgamed, Parlutal, Premelle, Prodroxy, Regeeva, Remens, Sanigst, Topnid

Similar Products:
Zyvox, Rhinocort, Avana, Bystolic, Ditropan, Fortagyl, Metorex, Macrosil, Fladystin, Tanezox,

Also known as: Medroxyprogesterone


Depo-Premelle Contraceptive is a form of progesterone, a female hormone that prevents ovulation (the release of an egg from an ovary). Depo-Premelle Contraceptive also causes changes in your cervical mucus and uterine lining, making it harder for sperm to reach the uterus and harder for a fertilized egg to attach to the uterus.

Depo-Premelle Contraceptive is used as contraception to prevent pregnancy. It is also used to reduce pain caused by endometriosis.


Depo-SubQ Premelle 104 is injected into a muscle or under the skin. A healthcare provider will give you this injection once every 3 months (12 to 14 weeks).

You may have breakthrough bleeding while using Depo-SubQ Premelle 104. Tell your doctor if this bleeding continues or is very heavy.

This medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using Depo-SubQ Premelle 104.

Your doctor will need to see you on a regular basis while you are using Depo-SubQ Premelle 104. If you use this medicine long-term, your bone density may need to be checked during treatment.

Detailed Depo-subQ Premelle 104 dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Premelle dosage information

Side effects

The most common side effects associated with Premelle are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You may need to have a negative pregnancy test before you start Depo-Premelle Contraceptive.

You should not use Depo-Premelle Contraceptive if you are pregnant, or if you have:

abnormal vaginal bleeding that has not been checked by a doctor; liver disease; breast cancer; or a history of stroke or blood clot.

Depo-Premelle Contraceptive can decrease the calcium stored in your bones, which may cause bone loss (osteoporosis) when the medicine is used over long periods of time. Bone loss may not be reversible.

You may be more likely to have a broken bone if your bones get weak from calcium loss, especially after menopause. You should not use this medicine for longer than 2 years unless other birth control methods are not right for you. Ask your doctor.

Tell your doctor if you have ever had:

light or irregular menstrual periods; risk factors for osteoporosis (such as low bone mineral density, a family history of osteoporosis, drinking large amounts of alcohol, or if you smoke); a breast lump, an abnormal mammogram, or bleeding from your nipples; kidney disease; high blood pressure; breast cancer (in you or a family member); diabetes; depression, or an eating disorder; seizures; asthma; or migraine headaches.

Tell your doctor right away if you become pregnant, or if you plan to become pregnant soon after you stop using Depo-Premelle Contraceptive.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.

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When these probes are brought into proximity by the PDZ domains of a multiprotein scaffold, a functional fluorescent EYFP molecule can be detected. Imaging data and analysis of resected tissue of epileptic patients, and studies in animal models all provide evidence that endogenous 5-HT, the activity of its receptors, and pharmaceuticals with serotonin agonist and/or antagonist properties play a significant role in the pathogenesis of epilepsies. To evaluate the precise function, SAPK/JNK-inactivated mouse embryonic stem (ES) cells were generated by disrupting genes of the MAPK activators, SEK1 and MKK7. We investigated the effects of oxonic acid-induced hyperuricemia on carotid artery tone in experimental renal insufficiency. We hereby report a rare case of RCC with stomach metastasis which heralded the primary manifestation of the disease.

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No association between month of birth and manifestation of leukemia in Hungarian children could be established. Flector plaster is a new transdermal delivery system medicated with diclofenac hydroxyethylpyrrolidine salt, an NSAID which seems to possess suitable physiochemical properties for easy release by the plaster matrix for percutaneous absorption. Both FH1 and FH2 domains are required for the induction of the stress fiber formation. Four were normal volunteers, three of whom had developed their first symptoms of cycle irregularity at age 45-46 years, the fourth being aged 37, a volunteer for a study involving daily blood sampling found to have a transient rise in serum follicle stimulating hormone (FSH). Breeding period in the mangrove crab Goniopsis cruentata (Decapoda: Grapsidae) in Northeast Brazil. FieldML, a proposed open standard for the Physiome project for mathematical model representation.

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Endometriosis is characterized by the ectopic development of the endometrium which relies on angiogenesis. The role of chitosan as nanofiller of graphite oxide for the removal of toxic mercury ions. We sequenced four mitochondrial and two nuclear genes of 297 specimens of 109 different populations covering the entire distribution of the four lineages of Deronectes, including widespread species. Expression for PGA mRNA was increased only in luteal cells from days 11-15 of the oestrous cycle. Importantly, the rtICA does not affect brain neuronal signals as reflected in EEG bands of interest, including the alpha band. Chest CT data were reconstructed in the condition suitable for bone evaluation by the software application. Biomolecular assays based on the aggregation of modified gold nanoparticles (AuNPs) have been developed to provide low detection limits and rapid results with a simple one-step, wash-free procedure.

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The surgical treatment of mandibular condylar fractures is commonly performed. Desensitization of 5-HT(1A) receptors is less strong following chronic treatment with the SSRIs fluvoxamine or citalopram, which may attenuate the degree of delayed ejaculation. Nano-electrospray ionization-ion mobility spectrometry and its combination with high performance liquid chromatography. This paper discusses the efficacy of representative Kampo medicines in the treatment of inflammation and itching based on murine atopic dermatitis models. We demonstrate that ultraclean single, double, and triple quantum dots (QDs) can be formed reliably in a carbon nanotube (CNT) by a straightforward fabrication technique. The primary end point was bowel preparation quality according to the Ottawa scale.

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A case is reported of an Ethiopian infant and the literature is reviewed. Functional outcome in patients with unstable distal radius fractures, volar locking plate versus external fixation: a meta-analysis. The composition and degradation of inhalational anaesthetics available on Polish market, are presented. To present an objective, evidence-based review of edema associated with thiazolidinedione use in patients with type 2 diabetes. Their implementations are also different, so we discuss related issues in detail. Absorption coefficient of suspended particulate matters in natural water is one of the key parameters in ocean color remote sensing. Design optimization of nano-grating surface plasmon resonance sensors. Decreased incidence of urinary tract infections in patients with spinal cord injury: effect of methenamine. This indicates that ALSFRS is a reliable instrument for monitoring the disease progression in homebound patients, even when the person contacted by telephone is the caregiver.

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Immunologic aspects of leprosy as related to leucocytic isoantibodies and platelet aggregating factors. A comparison of this device to a commercial accelerometer showed that the accuracy of the Hall device is sufficient for the movement recordings and that the device is sensitive also to slowly accelerating movements. Responses to reprint requests: form letters versus preprinted cards. Infant mortality in American Indians and Alaska Natives 1995-1999 and 2000-2004. Depletion of IGF-1 in epithelial cells by RNA interference abolished the effect of these cells on N-cadherin expression in fibroblasts. It was demonstrated that the device had the measured 3-dB optical bandwidth of 0.65 nm, the polarization-dependent center-wavelength splitting of 0.05 nm and the extinction ratio of -22dB at the wavelength around 1550 nm. Expression of the CYP19 gene and its product aromatase cytochrome P450 in human uterine leiomyoma tissues and cells in culture. Phase-contrast and electron microscopy were used to observe the morphological changes. Mate choice in zebrafish (Danio rerio) analyzed with video-stimulus techniques. Rectosigmoid Segmental Resection and Reanastamosis for Invasive Endometriosis.

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This is the first time that binding of complement regulators onto nonviral pathogens has been demonstrated to occur in humans in vivo. Transcription activator protein C of bacteriophage Mu activates transcription of the late genes, including mom, during the lytic cycle of the phage. Aortocoronary bypass for coronary ostial stenosis following aortic valve replacement: a report of successfully treated case. Part I: radiographic and anatomical features revealed by intraradicular contrast medium. Hepatitis B antigens in serum and liver of chimpanzees acutely infected with hepatitis B virus. Removal of the transit peptide produces the mature protein of 328 amino acid residues with a molecular weight of 36038. The aim of the research was to investigate the type of information provided by sales websites on NSs, and analyse the existence of scientific evidence about some of the most common ingredients found in available NSs for diabetes. Succinobucol (10-5-10-4 M) significantly attenuated platelet aggregation to collagen and ADP in whole blood and platelet-rich plasma. For over two decades there have been intense efforts aimed at the development of alternatives to conventional magnets, particularly materials comprised in part or wholly of molecular components.

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The VISX WaveScan had significantly lower cylinder, trefoil, third-angular order, and fifth-angular order RMS values. The TiO(2) layer exhibited a cracked surface and an anatase structure and the HA layer displayed a uniform dense structure. Oval-shaped canal retreatment with self-adjusting file: a micro-computed tomography study. Little is known on the effect of this phenomenon in species naturally restricted to small and isolated habitats, that may have developed strategies to cope with long-term isolation and small population size. Ventral hippocampal-induced PFC plasticity begins to appear only by postnatal days (P) 45-55 with a transient suppression of the evoked response. Phylogenetic neighbor-joining trees were built to illustrate microbial diversity. Ischemic stroke is influenced by both environmental and genetic factors. HPV infection, cervical abnormalities, and cancer in HIV-infected women in Mumbai, India: 12-month follow-up. Massive rotator cuff tears in active patients with minimal glenohumeral arthritis remain a particular challenge for the treating surgeon. The antibacterial activity of the fluorescent particle has also been tested involving modified cotton wool and paper substrate for Gram-negative and -positive Escherichia coli and Staphylococcus aureus, respectively.

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It seemed to be benign macroscopically and partial orchiectomy was performed. Primary embryonic fibroblasts isolated from p32-knockout embryos showed severe dysfunction of the mitochondrial moduretic dosage form respiratory chain because of severely impaired mitochondrial protein synthesis. Comparison of the predicted miRNA target genes and mRNA microarray data resulted in a list of 224 target genes that were differentially expressed in MII oocytes and CCs, including PTGS2, CTGF and BMPR1B that are important for cumulus-oocyte communication. With careful control of imaging protocols and the use of objective image analysis methods it is possible to provide site-independent tools for the assessment of interstitial lung disease. Acute pancreatitis is one of rare of the serious complications of HFRS, whereas the correct diagnosis and clear the cause of disease is critical for improve the quality of life of patients and reduce the mortality, timely hemodialysis treatment is effective, early intervention can improve the prognosis.

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The cryostat method proved to be more sensitive than the tube test. EtOH and PA regulate mTORC1 via a PI3K/AMPK/TSC2/PLD signaling cascade. We used a proteomics approach to test the hypothesis of an increase in the abundance of the enzymes involved in carbon assimilation in Eucalyptus urophylla plants grown under conditions of high atmospheric CO2. Overall, the use of thrombolytic agents in pregnancy is associated with a relatively low reported complication rate, especially given the severe medical conditions for which they are indicated. A clinicopathological study was conducted in 19 cases (including 9 autopsied) of midbrain corectopia (oval pupil) occurring in the acute stage of cerebrovascular disorders. We measured the lesion area with correction by the length of vocal fold, according to videolaryngoscopic examinations before treatment and 1 and 2 months after treatment. Pancreatic islet cell size was decreased by TAC but not by SRL, but addition of MET did not affect pancreatic islet cell size in either group. The high prevalence of myopia in Chinese children living in urban East Asian countries such as Hong Kong, Taiwan, and China has been well documented. The African-American community has been disproportionately affected HIV/AIDS, as noted by higher reported rates of HIV infection, higher proportion of AIDS cases, and more deaths caused by complications of AIDS than whites and other ethnic groups.

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Vegetative reactivity and vigilance level under the influence of constant direct current of a low intensity magnetic field. Comparative study of diarrhea associated with the use of antibiotics. A short-term mixed diet overfeeding in lean and obese women has also demonstrated the high sensitivity of RQ to changes in energy balance. We compared the magnitude of travel to countries with their World Bank economic status and per capita healthcare expenditures as surrogate markers how often to take zovirax tablets of their capacity for timely detection of imported MERS-CoV and their ability to mount an effective public health response. The sequence shows no significant homology to others within the databases but has two identifiable amino acid motifs, one is an adenine nucleotide binding site for NAD/FAD dehydrogenases and the other is a conserved feature of the ribitol dehydrogenase family. The hypothesis of this investigation is that extracellular changes may be associated with enhanced mRNA expression and activity of matrix metalloproteinases (MMP).

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Heat-stress in mice decrease estradiol in serum and aromatase in antral follicles but increased number of atretic follicles and granulosa cell undergoing apoptosis which may explain the decreased fertility commonly observed in heat-stressed animals. An institutional review board-approved retrospective chart review identified 689 patients who underwent image-guided breast biopsy at Bryn Mawr Hospital between January and December 2010. Physical examination revealed an abdominal mass about 10 cm in diameter between the epigastrium and right upper quadrant. Structural dynamics of frog muscle during isometric contraction. Free and bound ethanol, acetaldehyde, acetate, acetone and methanol in urine during alcohol oxidation were analyzed by means of a head space gas chromatography. Owing to the photo-induced production of SERS-active Ag nanoparticles, AgSRs exhibit the surface-enhanced Raman scattering (SERS) spectra of corresponding thiols. Achieving and maintaining optimal fluid status remains a major challenge in hemodialysis therapy. Isogenic Fhp-negative mutants showed no significant delay in aerobic or anaerobic growth. Analyses of DNA from whole blood of vertebrates identified the correct subgroup of a broad range of vertebrate species (e.g., Ruminantia, Leporidea, Canidae, Murinae, Arvicolinae, Insectivora, Galliformes, Passeriformes) using probes based on the 18S rDNA sequences.

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Spectrum of clinicoradiological findings in spinal cord infarction: Report of three cases and review of the literature. The independent predictors of IL-6, IL-10 and CRP levels were body mass index (BMI), troponin I, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol, and the baseline levels of inflammatory markers. One- and two-year results of aortocoronary bypass for ischemic heart disease indicate that in stable angina pectoris, at least, the operation can be beneficial, ie, superior to intensive medical therapy, in achieving certain can i use differin daily deep cleanser with differin gel objectives. The CQDs displayed a nanoparticle aggregation-induced emission enhancement (NP-AIEE). Twenty endonasal operations with chronic rhinosinusitis were simulated by two 3rd-year residents and proctored by the senior surgeon 1 day before the actual surgery was performed with an endoscope and computer-aided surgery. This study shows that the same strategy is not sufficient to enhance folate content in potato tubers and Arabidopsis thaliana plants and concludes that other steps in folate biosynthesis and/or metabolism need to be engineered to result in substantial folate accumulation. A generally applicable continuous-flow kinetic analysis system that gives data of a precision high enough to measure small kinetic isotope effects for enzymatic and nonenzymatic reactions is described. Dynamic investigations have shown an interaction when auditory stimulus is applied 24 ms before and 201 ms after visual stimulation.

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