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Politrol (Calcitriol)
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Politrol

Politrol is a synthetic version of Vitamin D3 used to treat calcium deficiency with hypoparathyroidism and metabolic bone disease in people with chronic kidney failure.

Other names for this medication:
Alcee, Alfacal, Alfacip, Aristrol, Calbovic, Calcigra, Calcimet, Calcirol, Calcit, Caldikind, Calgel, Calosto, Calsonic, Caltop, Calvical, Citroj, Dmcal, Fovit, Ikmag, Koncal, Lctrol, Netxod, Ostriol, Politrol, Ritoca, Rockbon, Septriol, Sorvate, Sunmic, Trolec, Vitalpha

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Also known as: Calcitriol

Description

Generic Politrol is a synthetic vitamin D analog which is active in the regulation of the absorption of calcium from the gastrointestinal tract and its utilization in the body. The two known sites of action of Generic Politrol are intestine and bone. Generic Politrol receptor-binding protein appears to exist in the mucosa of human intestine. Additional evidence suggests that Generic Politrol may also act on the kidney and the parathyroid glands. Generic Politrol is the most active known form of vitamin D3 in stimulating intestinal calcium transport. In acutely uremic rats Generic Politrol has been shown to stimulate intestinal calcium absorption. The kidneys of uremic patients cannot adequately synthesize Generic Politrol, the active hormone formed from precursor vitamin D. Resultant hypocalcemia and secondary hyperparathyroidism are a major cause of the metabolic bone disease of renal failure. However, other bone-toxic substances which accumulate in uremia (eg, aluminum) may also contribute. The beneficial effect of Generic Politrol in renal osteodystrophy appears to result from correction of hypocalcemia and secondary hyperparathyroidism. It is uncertain whether Generic Politrol produces other independent beneficial effects. Politrol is also known as Calcitriol. Generic Politrol treatment is not associated with an accelerated rate of renal function deterioration. No radiographic evidence of extraskeletal calcification has been found in predialysis patients following treatment. The duration of pharmacologic activity of a single dose of calcitriol is about 3 to 5 days. Generic name of Generic Politrol is Calcitriol. Brand name of Generic Politrol is Politrol.

Dosage

Generic Politrol is available in capsules (0.25 mcg) and liquid form. Capsules must be swallowed whole. Do not crush or chew them. If you are prescribed the liquid form, use as directed. Follow dosing instructions closely. Do not take this medication with mineral oil or magnesium containing antacids which may reduce its effects. Foods rich in vitamin D include: fortified dairy products, eggs, sardines, cod liver oil, chicken livers and fresh-water fish. Vitamin D is also obtained from periodic exposure to the sun. It is important to maintain a well-balanced diet while taking this medication. Calcium supplements may be recommended in addition to this medication. If you want to achieve most effective results do not stop taking Generic Politrol suddenly.

Overdose

If you overdose Generic Politrol and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Politrol are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

It is especially important that you receive the right amounts of vitamins so that your baby will also get the vitamins needed to grow properly. Infants who are totally breast-fed and have little exposure to the sun may require vitamin D supplementation. However, taking large amounts of a dietary supplement while breast-feeding may be harmful to the mother and/or baby and should be avoided.

Only small amounts of alfacalcidol, calcifediol, calcitriol, or dihydrotachysterol pass into breast milk and these amounts have not been reported to cause problems in nursing babies.

It is not known whether doxercalciferol or paricalcitol passes into breast milk. Be sure you have discussed the risks and benefits of the supplement with your doctor.

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We retrospectively reviewed all 306 patients undergoing primary lung transplantation from 1/2001 to 1/2006 with regard to the different forms of ECMO use. In this paper, we study the problem of Web video event recognition, where Web videos often describe large-granular events and carry limited textual information. The phagocytic, oxygen free radical generating and cytotoxic activities of macrophages from C57BL/6J mice fed either a normal or an atherogenic high-fat diet have been investigated. Long-term results of pectoralis major muscle transposition for infected sternotomy wounds. CYFRA21-1 as a serum tumor marker for follow-up patients with squamous cell lung carcinoma and oropharynx squamous cell carcinoma. Non invasive diagnosis of fetal diseases by maternal blood tests. Fever in the tropics: aetiology and case-fatality - a prospective observational study in a tertiary care hospital in South India. To ascertain if there are specific sociocultural and behavioural practices associated with the exposure to saliva, semen and vaginal fluids, particularly through child-rearing practices and the use of traditional medicine in Lusaka, Zambia. In the present study, we have found that intestinal flora strongly influence peritoneal neutrophilic inflammatory responses to diverse stimuli, including pathogen-derived particles like zymosan and sterile irritant particles like crystals.

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Significance and consideration of establishing surgical standard in the low and ultra-low anastomosis sphincter-preserving operation. Reverse transcriptase and quantitative real-time PCR (qRT-PCR) revealed that mice immunized with the DRF-412 vector contained less viral RNA in lung tissue and the lung immunohistology study confirmed that mice immunized with DRF-412 had better protection than those immunized with the DRF-412-P vector. Collinsia sparsiflora in serpentine and nonserpentine habitats: using F2 hybrids to detect the potential role of selection in ecotypic differentiation. The requirement for sound statistical analysis is stressed, and inadequacies in the techniques of follow-up are indicated. The evolution of interventional treatments of peripheral arterial disease is progressing at a dizzying pace. These results provide further evidence of a seasonal pro-thrombotic state, which has a complex relationship with temperature. In addition, there exists a positive feedback interaction between free radicals and cyclooxygenase activity in ocular tissues, such that during hypertension the cyclooxygenase pathway is an important producer of free radicals and in turn is also activated by them. In multilevel models with interactions between affect and age or disease, individual differences in NA predicted worse SRH primarily in older people. In all isolates the bla(CMY16) gene was not transferable by conjugation and was found to be carried on the chromosome. X-dll3 and X-dll4, which belong to the same subfamily, have a similar but not identical pattern of expression that is restricted to anterior ectodermal derivatives, namely the ventral forebrain, the cranial neural crest and the cement gland.

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To assess the characteristics of enhanced magnetic resonance image with ultrasmall superparamagnetic iron oxide (USPIO) in the inflammatory and tumor metastatic rabbit model, and explore its relevance with histologic ultrastructural findings. Alteration of NMDA NR1 receptors within the paraventricular nucleus of hypothalamus in rats with heart failure. TAE226 inhibited the phosphorylation of FAK as well as the downstream effectors AKT, extracellular signal-related kinase, and S6 ribosomal protein in multiple glioma cell lines. It is suggested that these findings indicate collagen neogenesis. Muscle strength was assessed on the 30th day after the injection, and then the animals were sacrificed to determine the muscle mass and perform histological analyses to detect cellular infiltration, capillary and microvessel densities, fibrosis, necrosis and tissue regeneration. Small, dense LDL particles predict changes in intima media thickness and insulin resistance in men with type 2 diabetes and prediabetes--a prospective cohort study.

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A comparison of the effects of 5-hydroxyeicosatetraenoic acid and hepoxilin A3 on the plasticity of the snail neuronal cholinoreceptors. As noggin (NOG) and sclerostin (SOST) have recently been associated with the disease process in mouse and human studies, respectively, we explored the immune responses to these two molecules in AS. VAC therapy is effective to clean and prepare the wounds, cutting off the fasciitis process and reducing the hospital stay and patient discomfort. Age-related changes in the liver sinusoidal endothelium: a mechanism for dyslipidemia. Importance of correction of malposition and dental migration in periodontology. Clinical features of 149 patients with facio-auriculo-vertebral spectrum. More than half of African HIV patients with eosinophilia had positive parasitic serology, and were significantly more likely to have positive serology compared with African HIV patients without eosinophilia. The present study aimed to evaluate the safety and effectiveness of CE in pediatric patients with suspicious small bowel disorders.

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Behavioral and biochemical evaluation of sub-lethal inhalation exposure to VX in rats. Corneal curvature was measured by photokeratoscopy before and after pressure changes. The attachment sites were found to share a common core of 12 bp. Microbial fuel cell (MFC) for bioelectricity generation from organic wastes. In the primary brain tumor, GS-immunoreactivity was seen only in the astrocytoma cells. Synopsis of the articles selected for the IMIA Yearbook 2012 and an invited opinion paper written by leading scientists in this field. Longitudinal study of excretion of metabolites of polycyclic aromatic hydrocarbons in urine from two psoriatic patients. Ras-family small GTPases are key regulators of cytoskeleton dynamics, vesicular trafficking and nuclear function.

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Nursing models that integrate the positivist, existential and spiritual approach to understanding and caring for those with a dual diagnosis should be developed. Both of these combination of communicable and non communicable diseases are preventable if timely preventive measures and healthy life style is adopted. Recently, there has been increasing evidence that dermoscopy can also be useful in the diagnosis of some skin infections. The current study intended to explore these associations by using a prospective population-based cohort study. More often the survival and mortality gap between African-American and White prostate cancer patients decreases with age.

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Perfusion and cannulation strategies for neurological protection in aortic arch surgery. Chronic renal disease progression: treatment strategies and potassium intake. Community health workers (CHW) may be effective in the delivery of tobacco dependence treatment with underserved groups. Activation of Rap1 was involved in the RET/PTC1-mediated stimulation of the BRAF kinase and the p42/p44 mitogen-activated protein kinases. Note on the Abdominal Pores and Urogenital Sinus of the Lamprey. However, longer follow-up is needed to link noise to a poorly functioning implant.

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