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Plutamide (Flutamide)
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Plutamide

Plutamide decreases or stops the growth of cancer cells by decreasing the amount of testosterone (natural hormone in males) in men. This also relieves difficulty in passing urine and makes it easier for you to urinate.

Other names for this medication:
Cytomid, Drogenil, Flutacare, Flutam, Flutamide, Flutide, Plutamide, Prostamid, Ticum

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Also known as: Flutamide

Description

Plutamide is a medication belongs to a class of drugs known as antiandrogens. Plutamide is used along with drugs such as leuprolide to treat prostate cancer. Plutamide blocks the effect of the male hormone testosterone. Giving Plutamide with leuprolide, which reduces the body's testosterone levels, you can treat prostate cancer. Generic name of Plutamide is Flutamid. Brand name of Plutamide is Plutamide.

Dosage

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. To do so may increase the chance of side effects.

Flutamide should be taken together with other medicines used for surgery. Do not stop taking these medicines without checking with your doctor first.

This medicine comes with a patient information insert. Read and follow the instructions in the insert carefully. Ask your doctor if you have any questions.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage form (capsules): For prostate cancer: Adults—Two 125-milligram (mg) capsules three times a day every eight hours for a total daily dose of 750 mg. Children—Use and dose must be determined by your doctor.

Overdose

If you overdose Plutamide and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of overdosage: loss of appetite, vomiting, slow breathing, decreased activity, trouble walking.

Storage

Store between 2 and 30 degrees C (36 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Plutamide are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Plutamide if you are allergic to Plutamide components. Be careful with Plutamide if you have blood disorders, liver problems. Be careful with Plutamide if you smoke. Be careful with Plutamide if you take mibefradil, warfarin, sleep medicine, sedatives, tranquilizers, anti-anxiety drugs, narcotic pain relievers (e.g., codeine), psychiatric medicine, anti-seizure drugs, muscle relaxants, certain antihistamines (e.g., diphenhydramine). Avoid alcohol. Avoid driving machine. Avoid exposuring to sunlight or artificial UV rays (sunlamps or tanning beds). Avoid laboratory tests (e.g., liver function) are needed while taking Plutamide. Do not stop taking Plutamide suddenly.

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Immunotoxicological, biochemical, and histopathological studies on Roundup and Stomp herbicides in Nile catfish (Clarias gariepinus). Analogous reaction of 1 with 1,3-propanesultone yielded 6-O-(sulfo-n-propyl) derivatives (SPE-beta-CD, 3) of varying d.s. We report a rare case involving the external anal sphincter in a 24 year-old female. Direct observations were used to calculate rates of aberrant behavior, e.g., aggression toward self, for task versus play settings within the intermittent mechanical ventilation rates. To understand the distribution of GII-4 norovirus strains associated with gastroenteritis in the wider population, we characterised the GII-4 norovirus strains detected during studies of sporadic cases depakote er 250 mg para que serve of infectious gastroenteritis collected in the UK and Malawi between 1993 and 2009. Perlecan, a matrix-associated HSPG found in the basement membrane of normal bronchial epithelium, was consistently undetectable in invasive bronchogenic carcinomas. Ex vivo adenoviral-mediated gene transfer to lung isografts during cold preservation. The saccharine test can be used for following up the effect of septoplasty upon nasal mucosa. Synonymous substitutions in the Xdh gene of Drosophila: heterogeneous distribution along the coding region. They further extend animal and human genetic studies linking Arginine Vasopressin to sexual behavior in males.

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