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Phenergan (Promethazine)
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Phenergan

Phenergan is a cheap medication with multiple uses, but is most commonly prescribed for nausea and vomiting due to chemotherapy, surgery, motion sickness, or pregnancy. While it's available in different forms making it easier to take, it can make you feel very sleepy and can't be used in children under 2 years old.

Other names for this medication:
Aceegan, Admol, Avomine, Basiprom, Calmkid, Ceedokid, Citazine, Emispan, Ethamol, Fevril, Hyperex, Kidkof, Lincotuss, Metacet, Nimkair, Paracee, Petrox, Phenazine, Pizol, Primozyn, Procalm, Progene, Promegan, Promethazine, Promethegan, Promit, Prophen, Prosed, Prosym, Prozine, Pyrex, Romet, Symol, Synergan, Tixylix, Vomica

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Also known as: Promethazine

Description

Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

Promethazine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Phenergan VC is a combination medicine used to treat sneezing, runny nose, watery eyes, hives, skin rash, itching, and other cold or allergy symptoms.

Dosage

This section provides information on the proper use of a number of products that contain promethazine. It may not be specific to Phenergan. Please read with care.

Never take rectal suppositories by mouth.

Wash your hands with soap and water before and after using this medicine.

To insert suppository: First remove the foil wrapper and moisten the suppository with cold water. Lie down on your side and use your finger to push the suppository well up into the rectum. If the suppository is too soft to insert, chill the suppository in the refrigerator for 30 minutes or run cold water over it before removing the foil wrapper.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For rectal dosage form (suppositories): For allergy symptoms: Adults and teenagers—12.5 milligrams (mg) before meals and at bedtime; or 25 mg at bedtime as needed. Children 2 years of age and older—Your doctor will determine dose based on the weight and/or size of the child. The dose is usually 6.25 to 12.5 mg three times a day; or 25 mg at bedtime as needed. Children younger than 2 years of age—Use and dose must be determined by your doctor . For prevention of motion sickness: Adults and teenagers—25 mg twice daily; this initial dose should be taken one-half to one hour before traveling. The dose may be repeated eight to twelve hours later if needed. On other days of travel, 25 mg may be taken on arising and again before the evening meal. Children 2 years of age and older—Your doctor will determine dose based on the weight and/or size of the child. The dose is usually 12.5 to 25 mg one-half to one hour before traveling. The dose may be repeated eight to twelve hours later if needed. Children younger than 2 years of age—Use and dose must be determined by your doctor . For nausea and vomiting: Adults and teenagers—25 mg for the first dose, then 12.5 to 25 mg every four to six hours if needed. Children 2 years of age and older—Your doctor will determine dose based on the weight and/or size of the child. The dose is usually 0.5 mg per pound of body weight (1.1 mg per kg) or 12.5 to 25 mg every four to six hours as needed. Children younger than 2 years of age—Use and dose must be determined by your doctor . For sedation: Adults and teenagers—25 to 50 mg. Children 2 years of age and older—Your doctor will determine dose based on the weight and/or size of the child. The dose is usually 12.5 to 25 mg. Children younger than 2 years of age—Use and dose must be determined by your doctor . For control of pain or anxiety before or after surgery: Adults and teenagers—50 mg the night before surgery; 25 to 50 mg after surgery. Children 2 years of age and older—Your doctor will determine dose based on the weight and/or size of the child. The dose is usually 0.5 mg per pound of body weight (1.1 mg per kg) or 12.5 to 25 mg the night before surgery or after the surgery. Children younger than 2 years of age—Use and dose must be determined by your doctor .

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include overactive reflexes, loss of coordination, severe drowsiness or weakness, fainting, dilated pupils, weak or shallow breathing, or seizure (convulsions).

Storage

Store at room temperature below 30 degrees C away from excess moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Phenergan are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Appropriate studies have not been performed on the relationship of age to the effects of promethazine injection in the pediatric population. Use of promethazine injection is not recommended in children younger than 2 years of age because of the increased risk of respiratory depression. Caution should be used when this medicine is given to children 2 years of age and older.

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The pregnane X receptor (PXR) and constitutive androstane receptor (CAR) are well-known xenobiotic-sensing nuclear receptors with overlapping functions. Clinically important drug-drug interactions can occur in immunocompromised transplant recipients who are treated for CMV infection. Antigenic comparison of foot-and-mouth disease virus serotypes with monoclonal antibodies. Burns patients require close monitoring, barrier nursing and sympathetic attitude of medical and paramedical staff in a burns ICU to have a reasonable chance of survival. We also found moderate construct and criterion validity for the social functioning scale of the SF-36 and considerable overlap between the general mental health and social functioning scales. Our analysis places the gene defect for this disorder in the region of DXYS1 and p58-1, near the centromere of the X chromosome. A chloride capturing system via proton-induced structure transformation between opened- and closed-forms of dodecavanadates. There was a direct relationship between the size of the secretory and CURL vesicles and the density of ASGP-Rs in their membranes. Factors such as nasal obstruction, mucosal irritation, and drug-induced parkinsonism should be given attention.

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Endothelin-1 (ET-1) is a potent vasoconstrictor and bronchoconstrictor but it has been shown to have also proinflammatory properties. We investigated leaf life span, the periods of leaf production and death, the time lag between leaf production and death, and the period of plant reproduction (i.e., flowering and fruiting). We show that it is feasible to design and manufacture a refractive logarithmic axicon that generates a quasi-diffraction-free/Bessel beam with nearly constant beam size and intensity over a predetermined range. This disease is due to absence or abnormality of the platelet membrane glycoprotein GPIb-IX-V, the receptor for von Willebrand factor. In this report, we present a case in which currently accepted methods of fetal assessment initially failed to demonstrate catastrophic fetal brain injury following a maternal motor vehicle accident. To characterize the influence of Gelofusine (succinylated gelatin) on the performance of point-of-care testing (POCT) for human chorionic gonadotropin (hCG) devices. Research and create new drugs by integrated traditional Chinese medicine and Western medicine. We hypothesized that RGD-CAP could be expressed in the PDL and regulate its mineralization. Traditional Chinese Medicine (TCM) and Ayurveda are considered as two of the most ancient systems of medicine, with history of more than two millennia. We present 2 cases of revision TTC arthrodesis using the pseudoelastic intramedullary nail.

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Development and evaluation of a secondary reference panel for BCR-ABL1 quantification on the International Scale. Creation of myelomeningocele in utero: a model of functional damage from spinal cord exposure in fetal sheep. We present a patient with low circulating complement (C) 3 levels who developed aHUS in the course of chronic active UC. Flavin reductases use flavins as substrates and are distinct from flavoenzymes which have tightly bound flavins. The effect of water intake on sweat production in hot environments.

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Mouse mammary tumour virus (MMTV) gene expression has been shown to be regulated by glucocorticoids. Three species were described for the Neotropical region, two from Costa Rica and one from Brazil, and one additional undescribed species from Colombia is reported here for the first time. We found that the V1 region, although highly variable, was indispensable for virus entry and infection, probably because V1 deletion mutants exhibited impaired processing of gp160 into mature gp120 and gp41. The present study was designed to evaluate the antihypercholesterolaemic effects of aqueous ginger (Zingiber officinale) infusion in hypercholesterolaemic rat models. The spirit lamp has been used as a mirror warmer in ear, nose and throat departments since the beginning of the speciality. Characterization of the antibody response in oesophageal cicatricial pemphigoid. The differentiation of columnar and hypertrophic chondrocytes is supported by Trps1 independent of Gli3.

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The Wnt genes encode a large family of secreted glycoproteins that play important roles in controlling tissue patterning, cell fate and proliferation during development. Cells are then grown in the presence of G418, and the medium is collected from 6 days after transfection. These studies demonstrate a novel role for CD45 in adhesion regulation and suggest a possible function for its association with CD45-associated protein. Nitric oxide (NO) has been implicated in the pathophysiology of endotoxemia, but few data exist concerning the effects of either NO synthase inhibition (NOSi) or volume resuscitation on microvascular regulation and tissue oxygenation. FDE was suspected due to lack of involvement of two mucosal sites and uneventful recovery. For that reason, we will focus in this review on the different signalling events that are triggered by p38 activity, and analyse how these events contribute to specific gene expression and cellular responses. We may expect that recombinant vaccine Revacs B based on L-IVP strain will cause no postvaccinal complications under conditions of an appreciable decrease in population immunity to vaccinia virus. Comparison of two modes of gathering information on tobacco use. Symmetric stretching vibration of CH4 in clathrate hydrate structures. This approach should consider assessing the effect of mode of feeding and the amount and type of energy fed, as well as the resulting growth patterns.

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The patients were reviewed in terms of age, sex, postoperative complications and length of hospital stay. Functional MRI evidence for subcortical participation in conceptual reasoning skills. A comparison of Freundlich isotherm parameters revealed isotherm linearity or nonlinearity was not significantly different between column chromatography and traditional batch experiments. Cyto-histologic aspects of viral infections and relation to carcinoma in situ. Neither high respiratory activity nor low total cellular activity, nor factors involved in osmoregulation, i.e., intracellular glycerol or activity of GPDH, correlated with the osmotolerant phenotype. This study provides insight into the mechanism of fragipain activation and, more generally, defines the role of the C11 activation loop in the control of peptidase activity and substrate specificity. Accurate detection of coronary artery disease by integrated analysis of the ST-segment depression/heart rate patterns during the exercise and recovery phases of the exercise electrocardiography test. For tumors 2.1 to 3 cm partial nephrectomy is better than thermal ablation.

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Synergistic effects of testosterone metabolites on the development of motoneuron morphology in a sexually dimorphic rat spinal nucleus. In the reinnervated muscles, the fibre distribution changed in response to the new nervous input and then remained constant. Atypic geniculate neuralgia: atypic anatomic correlation of cranial nerve roots and AICA. However, a fair amount of patients is rejected from surgery due to old age and preexisting comorbidities increasing operative mortality. The findings also suggest that the what does starlix cost novel SV40-derived vector may represent a fundamental improvement in the gene therapeutic armarmentarium.

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Mutagenic evaluation of 3,6-diamino-10-methyl-9,10-dihydroacridine (AcrH), a new synthesized acridine derivative was undertaken using short-term in vitro test. Most ulnar impaction syndrome cases have characteristic focal signal intensity changes in the ulnar part of the lunate. The conductivity of the ethanol-stimulated enrichments was as 5 folds (for propionate)/76 folds (for butyrate) as that of the traditional enrichments (never ethanol fed). The present study shows that there is a strong correlation between the ability of a PUFA to transfer an electron to a disulfide and its reported ability to modulate ionic channels. Our observations indicate that increased levels of albumin in the gastric aspirate, taken immediately after birth, may contribute to the development of RDS in preterm infants. According to this, we argue that the origin of cognition in natural systems (cognition as we know it) is the result of the appearance of aceon medicine an autonomous system embedded into another more generic one: the whole organism. The lens-specific proteins alpha and delta crystallins and lentoid bodies, structures that follow a differentiation pathway similar to that of the lens, regularly appear after 4 to 5 weeks in quail embryo neuroretina monolayer cultures. Body water (the volume of distribution, V, for both urea and creatinine) was estimated by the Watson anthropometric formulas.

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