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Phenergan (Promethazine)

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Phenergan is a cheap medication with multiple uses, but is most commonly prescribed for nausea and vomiting due to chemotherapy, surgery, motion sickness, or pregnancy. While it's available in different forms making it easier to take, it can make you feel very sleepy and can't be used in children under 2 years old.

Other names for this medication:
Aceegan, Admol, Avomine, Basiprom, Calmkid, Ceedokid, Citazine, Emispan, Ethamol, Fevril, Hyperex, Kidkof, Lincotuss, Metacet, Nimkair, Paracee, Petrox, Phenazine, Pizol, Primozyn, Procalm, Progene, Promegan, Promethazine, Promethegan, Promit, Prophen, Prosed, Prosym, Prozine, Pyrex, Romet, Symol, Synergan, Tixylix, Vomica

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Also known as: Promethazine


Phenylephrine is a decongestant that shrinks blood vessels in the nasal passages. Dilated blood vessels can cause nasal congestion (stuffy nose).

Promethazine is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Phenergan VC is a combination medicine used to treat sneezing, runny nose, watery eyes, hives, skin rash, itching, and other cold or allergy symptoms.


This section provides information on the proper use of a number of products that contain promethazine. It may not be specific to Phenergan. Please read with care.

Never take rectal suppositories by mouth.

Wash your hands with soap and water before and after using this medicine.

To insert suppository: First remove the foil wrapper and moisten the suppository with cold water. Lie down on your side and use your finger to push the suppository well up into the rectum. If the suppository is too soft to insert, chill the suppository in the refrigerator for 30 minutes or run cold water over it before removing the foil wrapper.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For rectal dosage form (suppositories): For allergy symptoms: Adults and teenagers—12.5 milligrams (mg) before meals and at bedtime; or 25 mg at bedtime as needed. Children 2 years of age and older—Your doctor will determine dose based on the weight and/or size of the child. The dose is usually 6.25 to 12.5 mg three times a day; or 25 mg at bedtime as needed. Children younger than 2 years of age—Use and dose must be determined by your doctor . For prevention of motion sickness: Adults and teenagers—25 mg twice daily; this initial dose should be taken one-half to one hour before traveling. The dose may be repeated eight to twelve hours later if needed. On other days of travel, 25 mg may be taken on arising and again before the evening meal. Children 2 years of age and older—Your doctor will determine dose based on the weight and/or size of the child. The dose is usually 12.5 to 25 mg one-half to one hour before traveling. The dose may be repeated eight to twelve hours later if needed. Children younger than 2 years of age—Use and dose must be determined by your doctor . For nausea and vomiting: Adults and teenagers—25 mg for the first dose, then 12.5 to 25 mg every four to six hours if needed. Children 2 years of age and older—Your doctor will determine dose based on the weight and/or size of the child. The dose is usually 0.5 mg per pound of body weight (1.1 mg per kg) or 12.5 to 25 mg every four to six hours as needed. Children younger than 2 years of age—Use and dose must be determined by your doctor . For sedation: Adults and teenagers—25 to 50 mg. Children 2 years of age and older—Your doctor will determine dose based on the weight and/or size of the child. The dose is usually 12.5 to 25 mg. Children younger than 2 years of age—Use and dose must be determined by your doctor . For control of pain or anxiety before or after surgery: Adults and teenagers—50 mg the night before surgery; 25 to 50 mg after surgery. Children 2 years of age and older—Your doctor will determine dose based on the weight and/or size of the child. The dose is usually 0.5 mg per pound of body weight (1.1 mg per kg) or 12.5 to 25 mg the night before surgery or after the surgery. Children younger than 2 years of age—Use and dose must be determined by your doctor .


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include overactive reflexes, loss of coordination, severe drowsiness or weakness, fainting, dilated pupils, weak or shallow breathing, or seizure (convulsions).


Store at room temperature below 30 degrees C away from excess moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Phenergan are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies have not been performed on the relationship of age to the effects of promethazine injection in the pediatric population. Use of promethazine injection is not recommended in children younger than 2 years of age because of the increased risk of respiratory depression. Caution should be used when this medicine is given to children 2 years of age and older.

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Effects of repeated treatment with methamphetamine plus scopolamine and methamphetamine on behavioral sensitization and conditioning. Evidence that acidosis alters the high-affinity dopamine uptake in rat striatal slices and synaptosomes by different mechanisms partially related to oxidative damage. We conclude that polymorphisms of the VDR have major effects on vitamin D function and metabolism, and should therefore be assessed in studies on vitamin D and MS. Several solutions to this problem of roller pumps generating an electrostatic charge when used with PVC pumphead tubing were identified. Delivery of unmodified bioactive ribozymes by an RNA-stabilizing polyethylenimine (LMW-PEI) efficiently down-regulates gene expression. This allowed us to separate patient populations for colorectal cancers, breast cancers, and gliomas for which clinical characteristics like survival times and times to relapse were analyzed.

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Relapse with rifamycin monoresistant tuberculosis occurred among HIV-seropositive tuberculosis patients treated with a once-weekly isoniazid/rifapentine continuation-phase regimen. Additionally many researchers are investigating whether repeatedly applying TMS to specific regions over several days to weeks might have therapeutic effects. Pulmonary diseases contribute significantly to the morbidity and mortality in children infected with the human immunodeficiency virus. Recently, neuroprotective effects of G-CSF have been reported in spinal cord disorders. During the period of October to November the incorporation of BrdU is weak, and in December there is a duplication of DNA metabolism.

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The pregnane X receptor (PXR) and constitutive androstane receptor (CAR) are well-known xenobiotic-sensing nuclear receptors with overlapping functions. Clinically important drug-drug interactions can occur in immunocompromised transplant recipients who are treated for CMV infection. Antigenic comparison of foot-and-mouth disease virus serotypes with monoclonal antibodies. Burns patients require close monitoring, barrier nursing and sympathetic attitude of medical and paramedical staff in a burns ICU to have a reasonable chance of survival. We also found moderate construct and criterion validity for the social functioning scale of the SF-36 and considerable overlap between the general mental health and social functioning scales. Our analysis places the gene defect for this disorder in the region of DXYS1 and p58-1, near the centromere of the X chromosome. A chloride capturing system via proton-induced structure transformation between opened- and closed-forms of dodecavanadates. There was a direct relationship between the size of the secretory and CURL vesicles and the density of ASGP-Rs in their membranes. Factors such as nasal obstruction, mucosal irritation, and drug-induced parkinsonism should be given attention.

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In this study, we assessed the predictive performance of different echocardiographic parameters including left ventricular hypertrophy (LVH) on future cardiovascular outcomes in elderly hypertensive patients without heart failure. Lacking effect of timing of surgery in relation to the menstrual cycle on prognosis of breast cancer in premenopausal women. Cognitive-behavioral intervention in menopausal symptomatology: short-term effects. Modelling decisions of a multidisciplinary panel for admission to long-term care. Measurement of inflammation and oxidative stress following drastic changes in air pollution during the Beijing Olympics: a panel study approach. Effects of acute and chronic interval sprint exercise performed on a manually propelled treadmill on upper limb vascular mechanics in healthy young men. The productivity losses were relatively low in comparison with other diseases, probably due to the fact that most patients with cerebrovascular disorders are elderly. The growth and enzyme data suggest that at low glucose concentrations and oxygen-limited conditions, the increase in biomass yields is a reflection of a redirection of ATP usage rather than a net increase in energy production. The case reported is one of ascites and bilateral hydrothorax in a patient with severe pre-eclampsia. The diagnosis of DP was confirmed by ultrasonographic assessment.

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Endothelin-1 (ET-1) is a potent vasoconstrictor and bronchoconstrictor but it has been shown to have also proinflammatory properties. We investigated leaf life span, the periods of leaf production and death, the time lag between leaf production and death, and the period of plant reproduction (i.e., flowering and fruiting). We show that it is feasible to design and manufacture a refractive logarithmic axicon that generates a quasi-diffraction-free/Bessel beam with nearly constant beam size and intensity over a predetermined range. This disease is due to absence or abnormality of the platelet membrane glycoprotein GPIb-IX-V, the receptor for von Willebrand factor. In this report, we present a case in which currently accepted methods of fetal assessment initially failed to demonstrate catastrophic fetal brain injury following a maternal motor vehicle accident. To characterize the influence of Gelofusine (succinylated gelatin) on the performance of point-of-care testing (POCT) for human chorionic gonadotropin (hCG) devices. Research and create new drugs by integrated traditional Chinese medicine and Western medicine. We hypothesized that RGD-CAP could be expressed in the PDL and regulate its mineralization. Traditional Chinese Medicine (TCM) and Ayurveda are considered as two of the most ancient systems of medicine, with history of more than two millennia. We present 2 cases of revision TTC arthrodesis using the pseudoelastic intramedullary nail.

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Development and evaluation of a secondary reference panel for BCR-ABL1 quantification on the International Scale. Creation of myelomeningocele in utero: a model of functional damage from spinal cord exposure in fetal sheep. We present a patient with low circulating complement (C) 3 levels who developed aHUS in the course of chronic active UC. Flavin reductases use flavins as substrates and are distinct from flavoenzymes which have tightly bound flavins. The effect of water intake on sweat production in hot environments.

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Mouse mammary tumour virus (MMTV) gene expression has been shown to be regulated by glucocorticoids. Three species were described for the Neotropical region, two from Costa Rica and one from Brazil, and one additional undescribed species from Colombia is reported here for the first time. We found that the V1 region, although highly variable, was indispensable for virus entry and infection, probably because V1 deletion mutants exhibited impaired processing of gp160 into mature gp120 and gp41. The present study was designed to evaluate the antihypercholesterolaemic effects of aqueous ginger (Zingiber officinale) infusion in hypercholesterolaemic rat models. The spirit lamp has been used as a mirror warmer in ear, nose and throat departments since the beginning of the speciality. Characterization of the antibody response in oesophageal cicatricial pemphigoid. The differentiation of columnar and hypertrophic chondrocytes is supported by Trps1 independent of Gli3.

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The patients were reviewed in terms of age, sex, postoperative complications and length of hospital stay. Functional MRI evidence for subcortical participation in conceptual reasoning skills. A comparison of Freundlich isotherm parameters revealed isotherm linearity or nonlinearity was not significantly different between column chromatography and traditional batch experiments. Cyto-histologic aspects of viral infections and relation to carcinoma in situ. Neither high respiratory activity nor low total cellular activity, nor factors involved in osmoregulation, i.e., intracellular glycerol or activity of GPDH, correlated with the osmotolerant phenotype. This study provides insight into the mechanism of fragipain activation and, more generally, defines the role of the C11 activation loop in the control of peptidase activity and substrate specificity. Accurate detection of coronary artery disease by integrated analysis of the ST-segment depression/heart rate patterns during the exercise and recovery phases of the exercise electrocardiography test. For tumors 2.1 to 3 cm partial nephrectomy is better than thermal ablation.

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The aim of this study was to assess the prevalence of COPD in the absence of chronic bronchitis (CB) based on a population survey in China, and to identify the determinants of CB in patients with COPD. Neither Mycobacterium spp nor influenza virus was detected with the polymerase chain reaction method during this study. An inhibitory activity of methylcobalamin on the proliferation was also observed in other cell lines (estrogen-sensitive B-1F cells from mouse Leydig cell tumor and MCF-7 cells from human mammary tumor) at the concentration of 500 micrograms/ml. However, in both conditions, the PMC(Lesion) group exhibited a longer RT and TA contraction latency of the affected leg than the healthy and PMC(Spared) groups. Sinking loss should be taken into account while studying the dynamics of Microcystis under light-availability control. Simultaneous analysis of seven alkaloids in Coptis-Evodia herb couple and Zuojin pill by UPLC with accelerated solvent extraction. In each case, we successfully describe the chain-length distribution, and give information about the kinetics, especially the probability of propagation versus deactivation by the RAFT mechanism. Suppressive effect of monocytes in vitro in patients with carcinoma of the uterine cervix.

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Synergistic effects of testosterone metabolites on the development of motoneuron morphology in a sexually dimorphic rat spinal nucleus. In the reinnervated muscles, the fibre distribution changed in response to the new nervous input and then remained constant. Atypic geniculate neuralgia: atypic anatomic correlation of cranial nerve roots and AICA. However, a fair amount of patients is rejected from surgery due to old age and preexisting comorbidities increasing operative mortality. The findings also suggest that the what does starlix cost novel SV40-derived vector may represent a fundamental improvement in the gene therapeutic armarmentarium.

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Z-100, extracted from Mycobacterium tuberculosis strain Aoyama B, inhibits the development of collagen-induced arthritis in mice. A theoretical model is derived to interpret the nonlinear process of pulse signal recovery through double-well potential theory. Normal maturation and hypertrophy did not affect lactate dehydrogenase activity or citrate synthase activity for the muscles with anaerobic fiber types. As of 1987, the state of Missouri had designated six adult trauma centers, two Level I and four Level II, for the metropolitan Kansas City, Mo, area, serving a population of approximately 1 million people. Prevalence and recognition of panic states in STARNET patients presenting with chest pain. This process has been proposed to be a major evolutionary force, shaping many life history imipramine pamoate brand name traits of species, and to govern global patterns of biodiversity at different scales. The development and reversibility of these changes by various treatments and by drugs is discussed.

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After either 3 or 6 months of training, intracortical microstimulation (ICMS) mapping was performed to document motor representations of the trained forelimb in the hemisphere ipsilateral to that limb. Histological observations showed no signs of any inflammatory reaction and there was no evidence of bony resorption. We analyzed findings in 8 patients (seven men and one woman, median age, 59 years) out of 17 patients with imatinib-resistant gastrointestinal stromal tumors who had been treated with sunitinib. Two prominent theories to explain the physiological effects of microgravity relate to the cascade of changes associated with the cephalic shifts of fluids and the absence of tissue deformation forces. Tunable carbon nanotube thin-film transistors produced exclusively via inkjet printing. Multi-directional lasing exhibiting the icosahedral symmetry was observed. Phylogenetic comparison of the photoaffinity-labeled benzodiazepine receptor subunits. Additionally, we have demonstrated that the PCB mixture (A1248) modulates both immune function and endocrine physiology in brown bullhead. The results showed that the nutritional status of the two groups was similar.

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Mutagenic evaluation of 3,6-diamino-10-methyl-9,10-dihydroacridine (AcrH), a new synthesized acridine derivative was undertaken using short-term in vitro test. Most ulnar impaction syndrome cases have characteristic focal signal intensity changes in the ulnar part of the lunate. The conductivity of the ethanol-stimulated enrichments was as 5 folds (for propionate)/76 folds (for butyrate) as that of the traditional enrichments (never ethanol fed). The present study shows that there is a strong correlation between the ability of a PUFA to transfer an electron to a disulfide and its reported ability to modulate ionic channels. Our observations indicate that increased levels of albumin in the gastric aspirate, taken immediately after birth, may contribute to the development of RDS in preterm infants. According to this, we argue that the origin of cognition in natural systems (cognition as we know it) is the result of the appearance of aceon medicine an autonomous system embedded into another more generic one: the whole organism. The lens-specific proteins alpha and delta crystallins and lentoid bodies, structures that follow a differentiation pathway similar to that of the lens, regularly appear after 4 to 5 weeks in quail embryo neuroretina monolayer cultures. Body water (the volume of distribution, V, for both urea and creatinine) was estimated by the Watson anthropometric formulas.

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Altogether, our study provides an alternative death pathway for the activated microglia-induced neuronal death by blockage of the caspase-3 protease cascade. Association of diabetes mellitus and hypertension predispose an individual to atherosclerotic cardiovascular disease. These data suggest that adrenaline may be participating in the action of these compounds on the burying behavior latency. Finally, it promotes the growth of B-cell clones derived from the parental 721/84.5 lines in the absence of fetal calf serum, which suggests that it could act as an autocrine growth factor in this Epstein-Barr virus-transformed B-cell line. We fabricate all-nanocrystal field-effect transistors on flexible plastics with electron mobilities of 21.7 square centimeters per volt-second. Thus, sequence duplications and gene transfer between organisms sharing the same environment are rarely expected to generate adaptive functions. 70 child/mother neurontin 300 mg price in egypt pairs who had participated continuously in the longitudinal study. In Rakai, Uganda, increasing community MMC and female ART coverage was associated with lower community HIV incidence in males. The patient received immunotherapy with Rituximab and obtained a good response that lasted 2 years. These results demonstrate that intravenous iron supplementation effectively treated the murine BA-induced AI without further enhancement of the inflammatory response.

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This analysis suggests that the survival of patients with advanced GCT may depend in part on kinetic variables present in the primary tumour. When considering the choice of coral as a bone substitute, these factors must be taken into account to allow the in situ maintenance of the implant over a sufficiently long period of time according to the clinical situation. In addition, the apparent rotational correlation time of Tempamine spin probes on surface sialic acid residues was smaller for the zinc deficient group, indicative of an increased rotational mobility of the spin label. The illuminance uniformities were calculated with Monte Carlo ray tracing simulations and the uniformity was found to increase with the increasing of certain LED-to-LED spacings anomalously. The results indicate that many can diflucan treat yeast infection errors are currently occurring in the way children are using restraints, as well as problems associated with the way child restraint systems are installed in vehicles.

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It is argued that aspects of the temporal dynamics of stability and plasticity in the hippocampal place cell representation both indicate modifications to, and inform the nature of, the synaptic plasticity in place cell models. Early-labor neuraxial analgesia does not increase the cesarean delivery rate compared with late epidural analgesia in nulliparas undergoing induction of labor. This review first outlines the limited ability of subcellular fractions such as liver microsomes to predict hepatic clearance in vivo. The effects of the phenoxyisopropionic acid derivative propaquizafop and its free-acid derivative on microsomal lauric acid hydroxylase and peroxisomal fatty acyl-CoA beta-oxidation have been investigated in primary cultured hepatocytes obtained from various species and compared with those induced by bezafibrate. Since routine morbidity and mortality conferences are sparse, and long-term outcome is not assessed, there is room for improvement. I outline methods of retarding or preventing osteoporosis and present management and treatment techniques that can be used with people who already have the condition. TPP was chosen as an effectively reactive oxygen species (ROS) producer. All patients received local injection of triamcinolone acetonide and lidocaine into the piriformis tendon. In precision-cut lung slices simvastatin reversed small arterial endothelial dysfunction, and partially reversed smoke-induced loss of vascular nitric oxide generation. A cross-sectional prevalence survey was conducted in the year 2013 to assess the post-treatment burden of trachoma in this population.

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