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Oncotam (Tamoxifen)

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Oncotam blocks the effects of estrogen. It is commonly used to treat breast cancer. It is also used to decrease the chance of breast cancer coming back in women who have received treatment for the disease. It may also help prevent breast cancer in women who have a high risk of developing breast cancer.

Other names for this medication:
Caditam, Mamofen, Oncomox, Oncotam, Tamodex, Tamoxifen, Tamtero, Tevafen, Tomifen, Valodex, Xifen

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Also known as: Tamoxifen


Tamoxifen is used to treat certain types of breast cancer (eg, estrogen receptor-positive breast cancer that has spread to other parts of the body [metastatic], early stage estrogen receptor-positive breast cancer after surgery and radiation treatment). It is also used to reduce the risk of invasive breast cancer in adult women with ductal carcinoma in situ (DCIS) after breast surgery and radiation treatment.

Tamoxifen is also used to reduce the risk for breast cancer in women with a high chance of getting it. The following are risk factors that may increase your risk of developing breast cancer:

If you have close family members (mother, sister, or daughter) with breast cancer. If you have ever had a breast biopsy or if high-risk changes in your breast(s) have been found from a breast biopsy. If you have never been pregnant or if your first pregnancy occurred at a late age. If your first menstrual period occurred at an early age.

Female hormones called estrogen, that occur naturally in the body can increase the growth of some breast cancers. Tamoxifen works by blocking the effects of estrogen in the body.

This medicine is available only with your doctor's prescription.


The dosage of Oncotam depends on the type of your disease and health state. Take Oncotam once or twice a day with or without food. Take Oncotam tablets orally at the same time every day with water. If you want to achieve most effective results do not stop taking Oncotam suddenly.


If you overdose Oncotam and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Oncotam overdosage: uncontrolled body shaking, unsteadiness, problems with walking, convulsions, lightheadedness, exaggerated reflexes, problems with breathing, tremor.


Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not store the oral liquid in the refrigerator or freezer. Throw away any unused liquid after 3 months of first opening the bottle.

Detailed Oncotam dosage information

Side effects

The most common side effects associated with Oncotam are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of tamoxifen in the elderly.

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Infantile Sialic Acid Storage Disease: Two Unrelated Inuit Cases Homozygous for a Common Novel SLC17A5 Mutation. Conditional logistic regression was applied to examine the interactions of occupational stress and GR gene polymorphisms with adjustment for potential confounders. Thus, the result of this study would serve as basis for the formulation of policies for the protection and conservation of these species and their habitats before these plants become extinct. The subsequent analysis revealed that fluorine does not possess a valence octopole but exhibits anharmonic thermal motion that can be modelled by the octopole multipole parameters. We interviewed 44 parents of children referred to EI by their pediatricians. In the present work, we sought to establish the role of CNP in the regulation of bile secretion in the rat and the possible pathways involved.CNP diminished basal as well as bile salt-evoked bile flow and bile acid output in a dose-dependent manner. High vs low confidence diagnoses were compared using the paired-samples t test.

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Concomitant administration of isoniazid reduced clofazimine levels significantly in tissues like small intestine, spleen, and foot pad and resulted in an increase in plasma levels. In this review, we try to embrace recent findings on the transcription factor Snail-mediated epigenetic silencing of E-cadherin. Indirect inputs to ventral temporal cortex of monkey: the influence of unit activity of alerting auditory input, interhemispheric subcortical visual input, reward, and the behavioral response. Recently, we have identified new functions of these nuclear receptors in steroidogenic tissues. Deformation of the cusps was less than the unrestricted shrinkage of the composite resins.

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De novo proximal duplication of 1(q12q22) in a female infant with multiple congenital anomalies. Novel pathogenetic mechanisms and structural adaptations in ischemic mitral regurgitation. Four CueO crystal structures were determined at different copper concentrations. A perinuclear accumulation of mitochondria characterizes the premetaphase I stages of reinitiated meiosis in the laboratory mouse oocyte. Although exact reduction parameters remain controversial, achievement of a satisfactory reduction becomes increasingly difficult with fracture comminution and overt bone loss. The adherence to clinical guidelines concerning dementia work-up is inadequate in the secondary health care sector.

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with minimal or no sample conditioning time--nevertheless provided a reliable guide as to how well that material would perform in subsequent 3-day chamber tests of VOC emissions. Now, miRNAs have been reported to be widely involved in antiviral immunity and have become a novel tool to study virus-host interaction. A portable anaerobic microbioreactor reveals optimum growth conditions for the methanogen Methanosaeta concilii. Cranioplasty with bone allografts dates from the Stone Age Celts. The objective was to assess the total body nitrogen (TBN) and total body protein (TBPr) contents of fat-free mass (P:FFM) in a group of healthy adolescent girls and to validate previously published TBN prediction equations.


Lawrence biodiversity, with special emphasis on bird assemblages. An alternative interpretation of the observations is that the radiation from R136a is dominated by a single superluminous object with the following approximate properties: luminosity and temperature as given above, a radius 100 times that of the sun, a mass 2500 times that of the sun, and a loss rate of 10(-3.5) solar masses per year. Analytical and numerical investigations show that intrinsic fluctuations may qualitatively and quantitatively affect both transient and stationary system behavior. They were evaluated by history, ICIQ-SF, physical examination, cystoscopy, UDS, and the 1-h pad test. A palpable mass over the anterolateral aspect of the knee was obvious and the last 3 months she was experiencing locking episodes with consequent knee effusion. Conducting school-based focus groups: lessons learned from the CATS project.

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Although non-invasive ventilation (NIV) efficacy in the treatment of acute hypercapnic respiratory failure (AHRF) have been previously demonstrated, not all the studies reveal this fact in the same degree, with some variability in the results. State of fasting was found to cause alterations within the glands indicating increased activity. For instance, P62 decreased more rapidly than P26 and P50 in both male and female belugas. By substituting non conserved amino acids present in the postulated alpha-helical region of zinc finger domains, we demonstrated that Cys2/His2 type zinc finger domains could be targeted to new DNA binding sites. We found RhoC to be expressed in clinical melanoma specimens and hypothesized that inhibiting its activation might prevent metastasis. Acute and phase-shifting effects of ocular and extraocular light in human circadian physiology. In addition, regular follow-up is necessary for the any cases with malignant potential.

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The main challenge of the microbead-based assay is in the immobilization of probe molecules onto the microbead surfaces. Five patients out of a group of ten who had dorsal column electrodes implanted for the relief of chronic pain were examined for the influence of the stimulation on the spontaneous pain and on the thresholds for touch, vibration and cutaneous pain induced by pinching. Oral morphine in either immediate release or sustained release form remains the analgesic of choice for moderate or severe cancer pain. Bubble and droplet motion in binary mixtures: Evaporation-condensation mechanism and Marangoni effect. The mean difference between normal and abnormal eyes of the APD group was 78.6 ms. Images acquired from biological samples in free space demonstrate that this new method provides the same detailed microscopic structure as that of conventional FFOCM. Tongue strength was assessed using the Iowa Oral Performance Instrument (IOPI).

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The aim of this study was to determine whether lactation protects the maternal hippocampus against damage induced by intracerebral application (ICV) of KA and if lactation decreases, or only delays, this damaging effect of KA. MAP kinases and mTOR mediate insulin-induced phosphorylation of insulin receptor substrate-1 on serine residues 307, 612 and 632. As a contribution to the problem of the immunological privilege of the fetus it was decided to investigate the fate of yolk sac grafts in mice. The aim of this study is to critically reconsider the direction of a relationship between HRQoL and illness acceptance in CHF patients. Use of variable ratio matching results in greater efficiency than pair matching and also greater bias reduction than matching at a fixed ratio. Pregnancy in the severely mentally ill patient as an opportunity for global coordination of care.

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Elevated costs of treatment in medical inpatients with psychiatric comorbidity are not reflected in the German DRG-system. The cerebrospinal fluid showed a mild pleocytosis and increased protein content. DAMGO was less effective at increasing the amplitude of later excitatory events compared with the effect of CGP 55845. Our results demonstrate that complex RNA tertiary structures, which may be difficult to predict computationally, form in vivo and can regulate RNA-editing events. To translate into Portuguese, back-translate, culturally adapt and validate a screening instrument for pervasive developmental disorder, the Autism Screening Questionnaire, for use in Brazil. Filling material left after retreatment procedure may harbour necrotic tissue and bacteria, which could lead to a persistent disease and reinfection of the root canal system. This critical information is necessary not only for the development of better, novel and potent anti-diabetic therapy in future but also for best possible combinational therapies and strategies with the available drugs. To determine whether Huntington disease (HD) mutation carriers have motor symptoms (complaints) when definite motor onset (motor phenoconversion) is diagnosed and document differences between the groups with and without unawareness of motor signs. An index of cell invasiveness is defined based on these parameters that reflects the overall ability of cells to transport across the gel surface interface, that is, invade the gel.

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Additional translational approaches, such as targeting telomeres using G-quadruplex ligands, should result in antitelomere agents, such as RHPS4, entering the clinic in the near future. This may account for side effects of neurontin 300 mg the differences observed, in formation of diphenylalanyl-tRNA and phenylalanyl-puromycin, between phe-tRNA bound non-enzymically to the P-sites of eukaryotic and prokaryotic ribosomes. Laparoscopic myomectomy offers a uterus-conserving alternative to hysterectomy for patients suffering from symptomatic myomas. Moderate weight loss is sufficient to affect thyroid hormone homeostasis and inhibit its peripheral conversion. These results indicate that zalcitabine and stavudine are possible candidates for the local and systemic treatment of adenoviral infection, and the anti-adenoviral effect might depend on the pharmacological properties of anti-HIV agents. X-ray microanalysis of the flushed beads showed that lead was present in a dose-related way in the uterine secretion of mice that had received 0.05, 0.1, or 0.15 mg lead per g body weight.

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Hypercalcemia related to cyclosporine A therapy following liver transplantation. The burden for the home setting was then unchanged from 3 weeks to 1 year, while outpatient rehabilitation showed a reduced burden over time. It consists of recognizing the weaknesses of the materials being used and handling them to the best advantage to minimize deleterious effects. THREE NOTABLE BOOKS ON THE HISTORY OF MATHEMATICS OF THE GREEKS. Pseudoaneurysm of the outflow chamber of the left ventricle as a complication of bacterial endocarditis of the aortic valve -- a clinical case. Endogenous tidal vertical migrations aid the retention of these planktonic larvae in estuaries near the parent populations. The 186ReO-222-N2S2(N-6-Ahx-BBN(7-14)NH2) complex showed stability in biological media, which indicates that the 222-N2S2 chelator is appropriate for chelating 186/188Re in radiopharmaceuticals involving peptides.

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Most of the KiSS-1 mRNA expressing cells contain ERalpha immunoreactivity in the AVPV and ARC. We demonstrate a suitable measurement technique with which to determine the cutoff wavelength and verify the technique by inspecting the near field of the modes that may be excited below and above the cutoff. Children are shaped in part by their environment and one rich in communication is therefore beneficial. Transcripts of audio recordings of neglect assessment team meetings were analyzed by using grounded theory analysis. Multiple myeloma (MM) is a poorly understood and uniformly fatal malignancy of antibody-secreting plasma cells (PC). Ingestion of marine debris can have lethal and sublethal effects on sea turtles and other wildlife. A benefit of the practice may be cost savings associated with shorter Intensive Care Unit and hospital length of stays. New radiocarbon dates and plant macrofossil data establish that parts of the Queen Charlotte Islands, British Columbia, were ice-free during and subsequent to the late Wisconsin glacial maximum on the Pacific coast of Canada. In addition, we did not reveal any significant differences between our two study groups concerning parameters defining FIV response.

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Results of this study illustrate the use of laminin-derived peptides as potential candidates for modification of biomaterials to support angiogenesis. The localization of CP-10 in vivo was examined using murine footpads injected with LPS and was found to be concentrated around the endothelial cells of the small blood vessels. But, the opposite symptoms appeared before elocon lotion generic the tum or size increased. Several risk factors are associated with cell phone use while driving including: parental cellphone use while driving, social norms for quick responses to text messages, and higher levels of temporal discounting. During iron limitation, it downregulates the expression of a number of iron-containing proteins, including enzymes of the tricarboxylic acid cycle and the respiratory chain. Long-term comparative outcomes between 2 common ureteroneocystostomy techniques for renal transplantation. Brief interventions delivered by primary care providers in a student health center to high-risk-drinking students may result in significantly decreased alcohol consumption, high-risk drinking, and alcohol-related harms.

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