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Oncotam (Tamoxifen)
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Oncotam

Oncotam blocks the effects of estrogen. It is commonly used to treat breast cancer. It is also used to decrease the chance of breast cancer coming back in women who have received treatment for the disease. It may also help prevent breast cancer in women who have a high risk of developing breast cancer.

Other names for this medication:
Caditam, Mamofen, Oncomox, Oncotam, Tamodex, Tamoxifen, Tamtero, Tevafen, Tomifen, Valodex, Xifen

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Also known as: Tamoxifen

Description

Tamoxifen is used to treat certain types of breast cancer (eg, estrogen receptor-positive breast cancer that has spread to other parts of the body [metastatic], early stage estrogen receptor-positive breast cancer after surgery and radiation treatment). It is also used to reduce the risk of invasive breast cancer in adult women with ductal carcinoma in situ (DCIS) after breast surgery and radiation treatment.

Tamoxifen is also used to reduce the risk for breast cancer in women with a high chance of getting it. The following are risk factors that may increase your risk of developing breast cancer:

If you have close family members (mother, sister, or daughter) with breast cancer. If you have ever had a breast biopsy or if high-risk changes in your breast(s) have been found from a breast biopsy. If you have never been pregnant or if your first pregnancy occurred at a late age. If your first menstrual period occurred at an early age.

Female hormones called estrogen, that occur naturally in the body can increase the growth of some breast cancers. Tamoxifen works by blocking the effects of estrogen in the body.

This medicine is available only with your doctor's prescription.

Dosage

The dosage of Oncotam depends on the type of your disease and health state. Take Oncotam once or twice a day with or without food. Take Oncotam tablets orally at the same time every day with water. If you want to achieve most effective results do not stop taking Oncotam suddenly.

Overdose

If you overdose Oncotam and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Oncotam overdosage: uncontrolled body shaking, unsteadiness, problems with walking, convulsions, lightheadedness, exaggerated reflexes, problems with breathing, tremor.

Storage

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not store the oral liquid in the refrigerator or freezer. Throw away any unused liquid after 3 months of first opening the bottle.

Detailed Oncotam dosage information

Side effects

The most common side effects associated with Oncotam are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of tamoxifen in the elderly.

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Infantile Sialic Acid Storage Disease: Two Unrelated Inuit Cases Homozygous for a Common Novel SLC17A5 Mutation. Conditional logistic regression was applied to examine the interactions of occupational stress and GR gene polymorphisms with adjustment for potential confounders. Thus, the result of this study would serve as basis for the formulation of policies for the protection and conservation of these species and their habitats before these plants become extinct. The subsequent analysis revealed that fluorine does not possess a valence octopole but exhibits anharmonic thermal motion that can be modelled by the octopole multipole parameters. We interviewed 44 parents of children referred to EI by their pediatricians. In the present work, we sought to establish the role of CNP in the regulation of bile secretion in the rat and the possible pathways involved.CNP diminished basal as well as bile salt-evoked bile flow and bile acid output in a dose-dependent manner. High vs low confidence diagnoses were compared using the paired-samples t test.

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De novo proximal duplication of 1(q12q22) in a female infant with multiple congenital anomalies. Novel pathogenetic mechanisms and structural adaptations in ischemic mitral regurgitation. Four CueO crystal structures were determined at different copper concentrations. A perinuclear accumulation of mitochondria characterizes the premetaphase I stages of reinitiated meiosis in the laboratory mouse oocyte. Although exact reduction parameters remain controversial, achievement of a satisfactory reduction becomes increasingly difficult with fracture comminution and overt bone loss. The adherence to clinical guidelines concerning dementia work-up is inadequate in the secondary health care sector.

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The aim of this study was to determine whether lactation protects the maternal hippocampus against damage induced by intracerebral application (ICV) of KA and if lactation decreases, or only delays, this damaging effect of KA. MAP kinases and mTOR mediate insulin-induced phosphorylation of insulin receptor substrate-1 on serine residues 307, 612 and 632. As a contribution to the problem of the immunological privilege of the fetus it was decided to investigate the fate of yolk sac grafts in mice. The aim of this study is to critically reconsider the direction of a relationship between HRQoL and illness acceptance in CHF patients. Use of variable ratio matching results in greater efficiency than pair matching and also greater bias reduction than matching at a fixed ratio. Pregnancy in the severely mentally ill patient as an opportunity for global coordination of care.

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Hypercalcemia related to cyclosporine A therapy following liver transplantation. The burden for the home setting was then unchanged from 3 weeks to 1 year, while outpatient rehabilitation showed a reduced burden over time. It consists of recognizing the weaknesses of the materials being used and handling them to the best advantage to minimize deleterious effects. THREE NOTABLE BOOKS ON THE HISTORY OF MATHEMATICS OF THE GREEKS. Pseudoaneurysm of the outflow chamber of the left ventricle as a complication of bacterial endocarditis of the aortic valve -- a clinical case. Endogenous tidal vertical migrations aid the retention of these planktonic larvae in estuaries near the parent populations. The 186ReO-222-N2S2(N-6-Ahx-BBN(7-14)NH2) complex showed stability in biological media, which indicates that the 222-N2S2 chelator is appropriate for chelating 186/188Re in radiopharmaceuticals involving peptides.

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Most of the KiSS-1 mRNA expressing cells contain ERalpha immunoreactivity in the AVPV and ARC. We demonstrate a suitable measurement technique with which to determine the cutoff wavelength and verify the technique by inspecting the near field of the modes that may be excited below and above the cutoff. Children are shaped in part by their environment and one rich in communication is therefore beneficial. Transcripts of audio recordings of neglect assessment team meetings were analyzed by using grounded theory analysis. Multiple myeloma (MM) is a poorly understood and uniformly fatal malignancy of antibody-secreting plasma cells (PC). Ingestion of marine debris can have lethal and sublethal effects on sea turtles and other wildlife. A benefit of the practice may be cost savings associated with shorter Intensive Care Unit and hospital length of stays. New radiocarbon dates and plant macrofossil data establish that parts of the Queen Charlotte Islands, British Columbia, were ice-free during and subsequent to the late Wisconsin glacial maximum on the Pacific coast of Canada. In addition, we did not reveal any significant differences between our two study groups concerning parameters defining FIV response.

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