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Nolvadex

Nolvadex attaches to the hormone receptors in the cancer cell, blocking estrogen from attaching to the receptors. This slows or stops the growth of the tumor by preventing the cancer cells from getting the hormones they need to grow.

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Caditam, Mamofen, Oncomox, Oncotam, Tamodex, Tamoxifen, Tamtero, Tevafen, Tomifen, Valodex, Xifen

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Also known as: Tamoxifen

Description

Tamoxifen is used to treat certain types of breast cancer (eg, estrogen receptor-positive breast cancer that has spread to other parts of the body [metastatic], early stage estrogen receptor-positive breast cancer after surgery and radiation treatment). It is also used to reduce the risk of invasive breast cancer in adult women with ductal carcinoma in situ (DCIS) after breast surgery and radiation treatment.

Tamoxifen is also used to reduce the risk for breast cancer in women with a high chance of getting it. The following are risk factors that may increase your risk of developing breast cancer:

If you have close family members (mother, sister, or daughter) with breast cancer. If you have ever had a breast biopsy or if high-risk changes in your breast(s) have been found from a breast biopsy. If you have never been pregnant or if your first pregnancy occurred at a late age. If your first menstrual period occurred at an early age.

Female hormones called estrogen, that occur naturally in the body can increase the growth of some breast cancers. Tamoxifen works by blocking the effects of estrogen in the body.

This medicine is available only with your doctor's prescription.

Dosage

The dosage of Nolvadex depends on the type of your disease and health state. Take Nolvadex once or twice a day with or without food. Take Nolvadex tablets orally at the same time every day with water. If you want to achieve most effective results do not stop taking Nolvadex suddenly.

Overdose

If you overdose Nolvadex and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Nolvadex overdosage: uncontrolled body shaking, unsteadiness, problems with walking, convulsions, lightheadedness, exaggerated reflexes, problems with breathing, tremor.

Storage

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

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The most common side effects associated with Nolvadex are:

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Robust optimal design of diffusion-weighted magnetic resonance experiments for skin microcirculation. Prediction of extended aromaticity for a novel C(48)N(12) azafullerene structure. A method is described for the design, evaluation, and application of internal control targets and probes for use in probe-based nucleic acid diagnostic assays (i.e., PCR-ELISA). The most common reason for this artefact is in vitro platelet clumping in blood samples collected into ethilenediaminetetraacetic acid (EDTA) anticoagulant. A total of 1533 aSAH patients from the Eastern Finland Saccular Intracranial Aneurysm Database were used in a recursive partitioning analysis (RPA) to identify risk factors for shunt placement after aSAH. Odor-aversion learning and retention span in neonatal mouse pups. Borderline personality disorder: Psychosocial considerations and rehabilitation implications.

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Web-based tailoring and its effect on self-efficacy: results from the MI-HEART randomized controlled trial. The adhesion of microvascular endothelial cells to their underlying basement membrane is important for the maintenance of vascular integrity. Data from gamma scintigraphic and quantitative biodistribution studies performed in M109 tumor-bearing Balb/c mice confirmed that (99m)Tc-EC20 predominantly accumulates in FR-positive tumor and kidney tissues. To fully understand the mechanisms and the terminology used, a robust classification algorithm to help ascribe the various etiologies is needed. Atypical fibroxanthoma with regional lymph node metastasis: report of a case and review of the literature. None of the children required brain stem evoked response audiograms to confirm the diagnosis. ADAM10 expression was upregulated in HCC tissues and cell lines, and was negatively correlated with the expression level of miR-449a in HCC tissues.

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