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Nexofex (Montelukast)

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Nexofex is a prescription medicine used for asthma prevention and for the treatment of allergy symptoms such as sneezing and runny nose. It reduces inflammation in the airways and make breathing easier.

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Also known as: Montelukast


Nexofex tablets, produced by Merck Sharp & Dohme, are indicated in the treatment of asthma as add-on therapy in those patients with mild to moderate persistent asthma who are inadequately controlled on inhaled corticosteroids. It helps prevent the wheezing, chest tightness, and shortness of breath caused by asthma and decreases the number of asthma attacks. The medicine is used to prevent exercise-induced bronchoconstriction (narrowing of the air passages in the lungs). It also helps treat seasonal and perennial allergic rhinitis. The active substance contained in the medication is Montelukast, a leukotriene receptor antagonist, that stops leukotrienes, chemical messengers in the immune system, from causing inflammation in the lungs and nose, preventing asthma symptoms and allergies.


Take Nexofex chewable tablets (4 mg, 5 mg, 10 mg), granules, film-coated tablets orally with water. Usually Nexofex is taken as a single dose at least two hours before you exercise. Do not take another dose of Nexofex for at least 24 hours. Usually Nexofex is taken once a day in the evening with or without food. Do not take Nexofex for asthma attack treatment that has already begun. If you want to achieve most effective results do not stop taking Nexofex suddenly.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep this medicine in the original bottle. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Nexofex are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Avoid situations or activities that may trigger an asthma attack.

If your asthma symptoms get worse when you take aspirin, avoid taking aspirin or other NSAIDs (nonsteroidal anti-inflammatory drugs) such as ibuprofen (Advil, Motrin), naproxen (Aleve), celecoxib, diclofenac, indomethacin, meloxicam, and others.

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This review provides an overview of the current status of our knowledge on the anatomical and electrophysiological changes occurring within the spinal cord that lead to, or are associated with the re-expression of locomotion in spinally-transected salamanders. Twelve-bed pediatric intensive care unit in an urban academic teaching hospital. Botulinum toxin-A is associated with significant improvement in OAB symptoms in patients with idiopathic OAB. Cross-validation of the General Neuropsychological Deficit Scale (GNDS). We outline the activity of microRNAs (miRNAs) and their associations with breast cancer and detail recent evidence of interactions between the ER and its cofactors and miRNA and provide an overview of the emerging field of miRNA-based therapeutics.

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