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Modafinil

Modafinil is a medication to treat sleepiness due to narcolepsy, shift work sleep disorder or obstructive sleep apnea. While it has seen off-label use as a purported cognitive enhancer to improve wakefulness in animal and human studies.

Other names for this medication:
Alertec, Carim, Dekast, Modafinil, Modafinilo, Modalert, Modapro, Modatec, Modavigil, Modfil, Modiodal, Provake, Renea, Vigia

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Dostinex, Nuvigil, Epivir, Zocor, Diflucan, Seroquel, Suprax, Cycram, Pioplus, Nifin, Imuran, Besprol, Lezest, Organosol, Lozar, Depranil, Easworm,

Description

How you take Modafinil may depend on what you’re taking it for.

Timing

If you’re taking Modafinil to reduce daytime sleepiness due to narcolepsy or sleep apnea, you’ll take it in the morning.

If you’re taking Modafinil for shift work sleep disorder, you’ll likely take it one hour before your work shift.

Modafinil will keep you awake for several hours, so you shouldn’t take it too close to your bedtime.

Taking Modafinil with food

You can take Modafinil with or without food. If the drug upsets your stomach, taking it with food might reduce this side effect. However, if you take it with food, Modafinil might take slightly longer to start working.

Can Modafinil be crushed?

Modafinil tablets should not be crushed or split. If you’re having trouble taking Modafinil, talk to your doctor or pharmacist about options that can make swallowing the tablet easier.

Dosage

Usual Adult Dose for Narcolepsy:

200 mg orally daily in the morning

Usual Adult Dose for Obstructive Sleep Apnea/Hypopnea Syndrome:

200 mg orally daily in the morning

Usual Adult Dose for Shift Work Sleep Disorder:

200 mg orally daily one hour prior to the start of the work shift

Usual Pediatric Dose for Attention Deficit Disorder:

Not FDA approved. Reports of serious dermatologic adverse effects and psychiatric events has resulted in the FDA's Pediatric Advisory Committee unanimously recommending that a specific warning against the use of modafinil in children be added to the manufacturer's labeling; use only if first- and second-line treatments have failed and the benefits outweigh the risks. Children less than 30 kg: 200-340 mg once daily Children more than 30 kg: 300-425 mg Randomized, double-blind, placebo-controlled pediatric studies have utilized an 85 mg film-coated tablet (currently not commercially available) to provide these dosages. All studies utilized a titration method but varied the length of titration (3 weeks vs 7-9 days); clinical improvement was noted earlier in the shorter titration period.

Detailed Modafinil dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of reach of children.

Side effects

The most common side effects associated with Modafinil are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

This medicine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.

Avoid other dangerous activities until you know how Modafinil will affect your level of wakefulness.

Avoid drinking alcohol while taking modafinil.

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