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Metforise

Metforise is the first-line medication for the treatment of type 2 diabetes, particularly in people who are overweight. It is also used in the treatment of polycystic ovary syndrome. It is not associated with weight gain and is taken by mouth.

Other names for this medication:
Bigomet, Cetapin, Diamet, Diapride, Diavista, Enselin, Etformin, Glidiet, Glital, Glucoact, Gluformin, Gremet, Insumet, Jalra, Melitus, Metkap, Metme, Metmin, Metneed, Metsafe, Metsar, Obimet, Ovinom, Pioglar, Resicon, Roftem, Triglucored, Vogic

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Also known as: Metformin

Description

Metforise is a famous medication which provides treatment type 2 diabetes. Metforise acts controlling and decreasing glucose (sugar in blood). Metforise is oral antihyperglycemic drug from the biguanide class. Metforise is also known as Metformin, Phage, Riomet, Fortamet, Glumetza, Obimet, Dianben, Diabex, Diaformin. Metforise is not taken to treat type 1 diabetes. You can normally take insulin while using Metforise. Generic name of Metforise is Metformin. Brand names of Metforise are Metforise XR, Fortamet, Riomet, Metforise, Glumetza, Diaformin, Diabex.

Dosage

Usual Adult Dose for Diabetes Type 2:

Immediate-release: Initial dose: 500 mg orally twice a day or 850 mg orally once a day Dose titration: Increase in 500 mg weekly increments or 850 mg every 2 weeks as tolerated Maintenance dose: 2000 mg daily in divided doses Maximum dose: 2550 mg/day Extended-release: Initial dose: 500 to 1000 mg orally once a day Dose titration: Increase in 500 mg weekly increments as tolerated Maintenance dose: 2000 mg daily Maximum dose: 2500 mg daily Comments: -Metformin, if not contraindicated, is the preferred initial pharmacologic agent for treatment of type 2 diabetes mellitus. -Immediate-release: Take in divided doses 2 to 3 times a day with meals; titrate slowly to minimize gastrointestinal side effects. In general, significant responses are not observed with doses less than 1500 mg/day. -Extended-release: Take with the evening meal; if glycemic control is not achieved with 2000 mg once a day, may consider 1000 mg of extended-release product twice a day; if glycemic control is still not achieve, may switch to immediate-release product. Use: To improve glycemic control in adults with type 2 diabetes mellitus as an adjunct to diet and exercise.

Usual Pediatric Dose for Diabetes Type 2:

10 years or older: Immediate-release: Initial dose: 500 mg orally twice a day Dose titration: Increase in 500 mg weekly increments as tolerated Maintenance dose: 2000 mg daily Maximum dose: 2000 mg daily Comments: Take in divided doses 2 to 3 times a day with meals. Titrate slowly to minimize gastrointestinal side effects. Safety and effectiveness of Metforise extended-release has not been established in pediatric patients less than 18 years of age. Use: To improve glycemic control in children with type 2 diabetes mellitus as an adjunct to diet and exercise.

Detailed Metforise dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose can cause severe hypoglycemia or lactic acidosis.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Metforise are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

You should not use MetFORMIN (Eqv-Metforise XR) if you are allergic to it, or if you have:

severe kidney disease; or metabolic acidosis or diabetic ketoacidosis (call your doctor for treatment).

If you need to have surgery or any type of x-ray or CT scan using a dye that is injected into your veins, you may need to temporarily stop taking MetFORMIN (Eqv-Metforise XR). Be sure your caregivers know ahead of time that you are using this medication.

Tell your doctor if you have ever had:

kidney disease (your kidney function may need to be checked before you take this medicine); high ketone levels in your blood or urine; heart disease, congestive heart failure; liver disease; or if you also use insulin, or other oral diabetes medications.

You may develop lactic acidosis, a dangerous build-up of lactic acid in your blood. This may be more likely if you have other medical conditions, a severe infection, chronic alcoholism, or if you are 65 or older. Ask your doctor about your risk.

Follow your doctor's instructions about using this medicine if you are pregnant or you become pregnant. Controlling diabetes is very important during pregnancy, and having high blood sugar may cause complications in both the mother and the baby.

MetFORMIN (Eqv-Metforise XR) may stimulate ovulation in a premenopausal woman and may increase the risk of unintended pregnancy. Talk to your doctor about your risk.

You should not breastfeed while using this medicine.

MetFORMIN (Eqv-Metforise XR) should not be given to a child younger than 10 years old. Some forms of MetFORMIN (Eqv-Metforise XR) are not approved for use by anyone younger than 18 years old.

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Rabies encephalitis in a patient with AIDS: a clinicopathological study. This late lactate elevation occurred after focal hyperintensities were identified by DWI. Immunohistochemistry, Western blotting and real-time polymerase chain reaction were used to detect placental LPL expression and activity. Co-incorporation of dexamethasone into the microspheres results in extended activity. In this study, we report that one of these alleles, wxG, has a tissue-specific phenotype with 30-fold more WX enzymatic activity in pollen than in the endosperm. The RNA-dependent RNA polymerase is associated with each viral RNA (vRNA) segment and in virus-infected cells, involved in both transcription, i.e. A total of 120 patients with type 2 DM (60 with DM duration of 120 months or less and 60, with more than 120 months) and 45 gender- and body mass index (BMI)-matched healthy adults were studied. cDNA cloning and mapping of the human creatine kinase M gene to 19q13. With special prepared measuring equipment we have varied the flow through elastic flexible tubes. This scenario prompted us to investigate the correlation between mast cell degranulation and neutrophil influx within the digits and knees joints of arthritic mice assessing what could be the functional role(s) of joint mast how much does glimepiride cost per month cells in the response to collagen immunization.

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Factor V Leiden: prevalence in the indigenous population and cases of thrombosis in North India. THz time domain spectroscopy of biomolecular conformational modes. Inter-operator and intra-operator reliability of tendon stiffness measurements of six operators were evaluated. In the twentieth century, a number of how long does 500 mg of flagyl stay in your system models of healthcare leadership were developed that were humanistic in focus. Machine Perfusion of Donor Livers for Transplantation: A Proposal for Standardized Nomenclature and Reporting Guidelines.

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