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Medroxyprogesterone is a progestin (female hormone). It works by replacing the natural progesterone hormone that the body is unable to make. This treats painful, irregular, or absent menstrual periods. It also prevents an overgrowth of the lining of the uterus in menopausal women taking estrogen (another female hormone).

Other names for this medication:
Curretab, Deviry, Empeea, Farlutal, Litmus, Medrigest, Medroxyprogesterone, Medtet, Megest, Megestone, Meprate, Orgamed, Parlutal, Premelle, Prodroxy, Regeeva, Remens, Sanigst, Topnid

Similar Products:
Celexa, Biaxin, Lopressor, Valium, Lamictal, Tenormin, Pamelor, Digossina, Aceper, Fenobrate, Satoren, Gallab, Endoxan,


Depo-Medroxyprogesterone (medroxyprogesterone) is a form of progesterone, a female hormone that prevents ovulation (the release of an egg from an ovary). This medicine also causes changes in your cervical mucus and uterine lining, making it harder for sperm to reach the uterus and harder for a fertilized egg to attach to the uterus.

Depo-Medroxyprogesterone and depo-subQ Medroxyprogesterone 104 injections are used as contraception to prevent pregnancy.

depo-subQ Medroxyprogesterone 104 injection is also used to reduce pain caused by endometriosis.


This section provides information on the proper use of a number of products that contain medroxyprogesterone. It may not be specific to Depo-SubQ Medroxyprogesterone 104. Please read with care.

A nurse or other trained health professional will give you this medicine in a hospital or clinic. This medicine is given as a shot into one of your muscles (usually in the buttocks or upper arm).

If you are using Depo-Medroxyprogesterone®: This medicine is initially given on a weekly basis, but the frequency may be less often over time.

If you are using Depo-Medroxyprogesterone CI®(contraceptive injection) or Depo-Subq Medroxyprogesterone 104®:

To make using hormonal contraceptives as safe and reliable as possible, you should understand how and when to use them and what effects may be expected. This medicine comes with patient information insert. Read them carefully and make sure you understand them before receiving this medicine. If you have any questions, ask your doctor. Your doctor must make sure you are not pregnant before you start treatment with this medicine. For most women, this means you must receive your first shot during the first 5 days of a normal menstrual period. You will need to receive this medicine every 3 months (12 to 14 weeks). Be sure to keep all appointments with your doctor to receive your injections. If you plan to start this medicine after having a baby, you should receive your first shot within 5 days after your baby is born. If you plan to breastfeed your new baby, talk to your doctor about when to get your first shot. Some doctors may suggest waiting 6 weeks before getting your first shot, but others may suggest getting the shot sooner after the baby is born. If you wait 6 weeks, talk to your doctor about using an alternative form of birth control. If you are switching from another method of birth control, carefully follow your doctor’s instructions about when to have your first injection of this medicine. You need to have enough calcium and vitamin D in your diet. Your doctor might suggest that you take supplements.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Medroxyprogesterone dosage information

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies on the relationship of age to the effects of Depo-Medroxyprogesterone CI® (contraceptive injection) or Depo-Subq Medroxyprogesterone 104® have not been performed in the pediatric population. However, pediatric-specific problems that would limit the usefulness of this medicine in teenagers are not expected. This medicine may be used for birth control in teenage females, but should not be used before the start of menstruation.

Appropriate studies have not been performed on the relationship of age to the effects of Depo-Medroxyprogesterone® in the pediatric population. Safety and efficacy have not been established.

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MID1 mutation screening in a large cohort of Opitz G/BBB syndrome patients: twenty-nine novel mutations identified. These results show that the measured total outdoor particle number concentrations in Rochester generally vary with similar temporal patterns, suggesting that the central monitoring site data can be used to estimate outdoor exposure in other parts of the city. Digital gene expression profiles in the medulloblastoma were compared to multiple regions of the normal human brain, revealing 30 transcripts with high expression in multiple tumors and little or no expression in the normal cerebellum and other adult and pediatric brain regions. Sleep quality affects cognitive functioning in returning combat veterans beyond combat exposure, PTSD, and mild TBI history. The cDNA clones showing different hybridization patterns were further analyzed and verified.

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Socio-economic level seems to be inversely related to the ACS in adolescents. Comparison of the invasiveness between reduced-port laparoscopy-assisted distal gastrectomy and conventional laparoscopy-assisted distal gastrectomy. Engineering the structural properties of DNA block copolymer micelles by molecular recognition. Asymmetries in these mutants are reversed compared to wild-type, and inhomogeneous stresses may cause asymmetries in wild-type closure. A number of parameters may be optimized to generate robust experimental formats, in high-density microtiter plates, that may be used for ligand identification and pharmacological characterization. To remove fluorophore emission cross-talk in wide-field multispectral fluorescence molecular imaging, we evaluate three different solutions: (1) image stitching, (2) concurrent imaging with cross-talk ratio subtraction algorithm, and (3) frame-sequential imaging.

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Knockdown of DISC1 caused a significant increase of cyclic adenosine monophosphate response element-binding protein (CREB) activity. Analysis of native forms and isoform compositions of the mouse 90-kDa heat shock protein, HSP90. Modelling memory functions with recurrent neural networks consisting of input compensation units: I. The purpose of this study was to determine how sleep quality affects cognitive functioning in returning combat veterans after accounting for effects of combat exposure, posttraumatic stress disorder (PTSD), and mild traumatic brain injury (mTBI) history. For these patients, the depth of the incisions and soft tissue makes it extremely difficult to insert pedicle screws along the pedicle axis. Falls are common in Italian elderly and are linked with the fragility of aging. The aim of this study is to investigate the effect of audio-visual components on environmental quality to improve soundscape.

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The proposed approach allows testing the effect of hypothesized mechanisms rather than speculating on their benefit for system performance or confidence in its responses. Comparative efficacy of various chemical stabilizers on the thermostability of a live-attenuated peste des petits ruminants (PPR) vaccine. Percutaneous kidney biopsy provides the most expedient means of establishing the diagnosis. This accurate expansion of the Jones matrix reveals in particular the amplitudes and phases of the cross-coupled components of the principal states of polarization, which are incorrectly described in most polarization mode dispersion models. Effective cervical decompression by the posterior cervical foraminotomy without discectomy.

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NoV is a common cause of diarrhea among SOT recipients at our institution and is responsible for a very prolonged course of chronic diarrhea. Measurement of flow-mediated dilation (FMD) is well known as a noninvasive method for an assessment of vascular endothelial function. This increase in use and consequent exposure to mobile communication (MC)-related EMF has led to concern about possible health effects that could arise from this exposure. Our results showed that the mice were able to discriminate object location when tested either 90 or 180 min after training. Peptidoglycan induces cyclooxygenase-2 expression in macrophages by activating the neutral sphingomyelinase-ceramide pathway. The aim of this study was to determine the adherence rates and the predictors of adherence in four key activities of a multifactorial fall prevention trial. The effect of testosterone or estrogen addition in vivo was assessed in ORX males in the surgical OA model. Available data suggest that inflammation is the major reason for the symptoms appearing after organic dust exposure.

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Mandibular reaction time to auditory and visual signals in young and elderly subjects. The developmental order of appearance of immunoreactivity in somata, dendrites and axons was different in various brain regions. THE GEOGRAPHICAL DISTRIBUTION OF THE STUDENT BODY AT A NUMBER OF EASTERN AND WESTERN UNIVERSITIES AND EASTERN COLLEGES. At rest, systolic FP values exceeded RR values by greater than or equal to 10 mmHg. Greater specificity in federal priorities can be expected to more clearly direct future research within this policy-research partnership. We estimate group-based dating violence trajectories and identify the adolescent risk factors that explain membership in each trajectory group. The method was used in the evaluation of the progress of osteogenic activity in mandibular bone grafts in 24 beagle dogs. The diagnosis of intermittent explosive disorder in violent men.

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Evidence will be provided which supports that Western life style permanently boosters IR from intrauterine life to senescence. High affinity platelet alpha 2-adrenergic receptor density is decreased in older humans. Diagnosis of narcolepsy with cataplexy was based on International Classification of Sleep Disorders criteria with clinical, standard polysomnographic, and Multiple Sleep Latency Test features. By the direct digitalization of the ultrasonic echo images, more information is obtained from the reflected echo signals. Blood lymphocytes have a peak corresponding to relative high electrophoretic mobility, whereas the majority of marrow lymphocytes is found in fractions corresponding to low electrophoretic mobility. Blood samples from ten healthy donors were collected in various serum and plasma tubes and Ficolin-2 properties were evaluated by different ELISA setups.

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A comparative evaluation of off-the-shelf distributed semantic representations for modelling behavioural data. Although lipolysis is increased during pST treatment of growing pigs, the greatest consequence is decreased lipogenesis. Using the so-called barbiturate effect in the electroretinogram as a functional criterion, complete ischemia can be shown to take place in rabbit and cat at intraocular pressures of 100 mm Hg. Heparan sulfates and the decrease of N-glycans promote early adipogenic differentiation rather than myogenesis of murine myogenic progenitor cells. Development of a magnetic nanoparticles microarray for simultaneous and simple detection of foodborne pathogens. Secondary structure model of the naked segment 7 influenza A virus genomic RNA. Topics include host skin penetration behavior in blood flukes, oocyte maturation in starfishes, prevention of polyspermic fertilizations in sea urchins, ion regulation in bivalves, egg production in snails, egg release in scallops, neurobiology of Aplysia, hatching in barnacles, and release of egg-laying behavior in some insects. We sought to identify risk factors and determine mortality rates for these two entities. Deregulated expression of the c-myc oncogene abolishes inhibition of proliferation of rat vascular smooth muscle cells by serum reduction, interferon-gamma, heparin, and cyclic nucleotide analogues and induces apoptosis. These results indicate that central neuronal histamine and histamine receptors are significantly involved in the opioid-induced stimulation of the pituitary-adrenal axis in rats.

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These included supply side barriers: Shortage of qualified health workers, bad staff attitude, poor relationships between community and health staff, long waiting time, confidentiality and the gender of health workers. Previous instruments require training and/or they are time-consuming (e. Radiosensitivity and effect of hypoxia in HPV positive head and neck cancer cells. Visualization of plant cell wall lignification using fluorescence-tagged monolignols. Graham Little - Piccardi - Lassueur (GLPL) syndrome is a rare dermatosis characterized by scarring alopecia, loss of pubic and axillary hair, and progressive development of variously located follicular papules. Observed Handwashing with Soap Practices Among Cholera Patients and Accompanying Household Members in a Hospital Setting (CHoBI7 Trial). A series of 2-amino-5-bromo-4(3H)-pyrimidinone derivatives bearing different substituents at the C-6 position were synthesized using a highly regioselective lithiation-substitution protocol, and the effect of structural variation at the C-6 position on their antiviral activity in cell culture was evaluated. Heart failure is the only major cardiovascular disease with an incidence and prevalence that continue to increase in the developed world. These results further support the concept that swine can serve as a reservoir of genetically stable influenza viruses. Originally discovered as an antiviral substance, the efficacy of IFN-alpha in malignant, viral, immunological, angiogenic, inflammatory, and fibrotic diseases suggests a spectrum of interrelated pathophysiologies.

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To contribute to this effort, we here study an optical probe, N-acetylaladanamide (NAAA), in the presence of a POPC lipid bilayer using a multiscale integrated approach to assess the probe structure, dynamics, and optical properties in its membrane-bound status and in water solvent. The burden of disease of influenza in Germany has been dominated by high rates of complications in elderly patients in years with high circulation of H3N2 viruses after the introduction of the new H1N1 strain in 2009. Replacement of one, two, or all three of the D-2-hydroxyisovalerate constituents in beauvericin (1) with 2-hydroxybutyrate moieties (beauvericins G(1-3), compounds 2-4) caused a parallel decline of cell migration inhibitory activity and cytotoxicity, suggesting a requirement for a branched side chain for both of these biological activities at the corresponding positions of beauvericins. This manifested as a Budd-Chiari syndrome-like phenomenon that was not recognized until an exploratory operation was performed, when we found that the liver was hard and dark purple in colour and there was considerable ascites in the abdominal cavity. Oxygen, Silicon, and Aluminum in Lunar Samples by 14 MeV Neutron Activation. By in silico analysis, four miRNAs (miR-146a, miR-155, miR-370, and miR-708) were selected as potential regulators of the FOXO1 gene. Three-Dimensional Surface Imaging is an Effective Tool for Measuring Breast Volume: A Validation Study. The differentiation from cystic metastases to lymph nodes is pointed out. Activation of the endoplasmic reticulum (ER) stress response pathway may in part explain the combinatorial synergy. Although the available data are less conclusive in comparison with venlafaxine XR, escitalopram is at least as cost effective as the SNRI based on a prospective study, and potentially more cost effective based on modelled analyses.

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To share our surgical experience and the outcome of limited pancreatic head resection for the management of branch duct intraductal papillary mucinous neoplasm (IPMN). Bone morphogenetic proteins (BMPs) are known to exert a multitude of diverse differentiation effects during embryonic development. Index cases who disclosed genetic test results dulcolax tablets 5mg side effects to healthcare providers within 6 months were more likely to have endoscopy within 12 months. The posterior fusiform gyrus lies in a surgically challenging region. Combined open and endovascular treatment of thoracoabdominal aortic pathologies: a systematic review and meta-analysis. Stent thrombosis with ticagrelor versus clopidogrel in patients with acute coronary syndromes: an analysis from the prospective, randomized PLATO trial. Calcaneal bone mineral density in young adults prescribed selective serotonin reuptake inhibitors.

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From 5 May (day 0), 16 of the ewes received an oral dose of 3 mg melatonin in a 4:1 (v:v) mixture of water and ethanol daily at 15:00 h. These in-vitro results could be the starting point of a new idea for the treatment of patients with intermittent claudication. The findings of this study might provide new insights for understanding the functions of miRNA in stress response in plants. Orthogonal coiled-coil dimers seem like an ideal building module due to their shape, adjustable length, and above all their designability. All such cases were additionally evaluated under polarized light microscope to detect microcalcifications containing birefringent calcium oxalate deposits. Complete sequence of Sipunculus nudus erythrocyte histone H2B and its gene. Magnetic resonance imaging of bone tumours and mimics: pictorial essay. Free secretory component from cystic fibrosis sputa displays the cystic fibrosis glycosylation phenotype. Cytolysis was closely correlated (r equal 0.91, p less than 0.05) with the histologica grade of cellular rejection but not with humoral rejection, suggesting that cytotoxic lymphocytes are an important element in cellular rejection.

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Initial medical examination suggested inclusions of smegma and they were referred to our Department of lanoxin syrup price philippines Pediatric Urology. Acoustic, textural and morphological features of the breast in ultrasound imaging were extracted for computer-aided diagnosis. The present study provides the first description of two monoclonal antibodies (mAbs) (5E8 and 3D7) directed against the TGEV N protein linker region (LKR) and carboxyl terminal domain (CTD). Prevalences of diabetes, standardized to the population structure of 2004, and trends over time were assessed for the total study population as well as by gender and other diabetes-associated factors. Trials have shown that patients with multiple-brain metastases and poor prognostic features have a short median survival after whole-brain radiotherapy (WBRT). Information about participants, intervention type, suicide outcomes, primary analytic method used for linkage, statistical approach, analyses performed, and characteristics of data systems was abstracted by 2 reviewers. To compare treatment results with use of nab-paclitaxel in routine clinical practice with data obtained from clinical trials.

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Despite recognition of COPD as an important international health problem, COPD has been neglected among common diseases, with little investment in research on its underlying cellular and molecular mechanisms. Robert Miller: a frontline fighter of amyotrophic lateral sclerosis. In this study, we sought to determine whether pertussis toxin (PT), an exotoxin virulence factor produced exclusively by Bordetella pertussis, is important for colonization of the respiratory tract by this pathogen by using a mouse intranasal infection model. Potential for TACT to accurately detect osseous healing in surgical defects was demonstrated. Speaking out about abuse also helps survivors, freeing them from a sense of shame, guilt, and humiliation and providing an avenue of political engagement that can be tremendously empowering. Thermodynamics and mechanism of alpha helix initiation in alanine and valine peptides. The taskforce recommend that before initiating therapy, some form of geriatric assessment should be conducted that includes evaluation of comorbidities and polypharmacy, hydration status and renal function (using available formulae). Positron emission tomography (PET) imaging is a useful tool for quantifying various aspects of the distribution of neuroreceptors throughout the human brain in vivo. The nature of strong ground motions recorded during subduction earthquakes of M(w) less than 8.2 is discussed. The results show that dietary vitamin E effectively prevented lipid peroxidation at the LCP concentrations investigated and suggest that levels presently in infant formulas are sufficient.

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A new approach is described for probing domains of ordered self-assemblies of amphiphilic monolayers at the aqueous solution interface. A series of new benzimidazole derivatives were synthesized and tested in vitro for possible anticancer activity. The purpose of this paper is to propose a framework to locate the active region of the corresponding MTUs within a single skeletal muscle and to analyze the activation level varieties of different MTUs during a dynamic motion task. Carney atenolol 25 mg u 22 complex (CNC) is an autosomal dominant disorder associated with multiple neoplasms. The similarities in the distributions of Fe and Ni in all types of sediments are the result of geochemical similarity as well as of the fact that natural sources mainly affect the concentration levels of these elements. Our study demonstrates that the intra-operative use of a microscope does not improve overall surgery-related outcomes, nor does it lead to superior long-term outcomes in pain and functional disability, 2 years after index surgery. Elevated levels of polyamines have long been associated with skin tumorigenesis. The central actions of the hormone leptin in regulating energy homeostasis via the hypothalamus are well documented.

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We also investigated other factors affecting the mode of evolution in the disease genes: Ka/Ks is significantly affected by protein function, mode of inheritance, and the reduction of life expectancy caused by disease. As predicted, the 2D:4D in males was smaller than females in all of the groups. HPV may have acted as a cocarcinogen in the development of SCC in two patients and extensive condyloma acuminatum in one. There was severe facial swelling and left exophthalmus, and enucleation of the eye was necessary. Abundance of repetitive sequence elements in the mouse testis-specific lactate dehydrogenase-C gene. These data provide the first molecular insight into how skelemin may interact with integrins and regulate integrin-mediated signaling and cell spreading. Data from the Aerobics Center Longitudinal Study representing 43,727 participants with 699,632 person-years of follow-up were included. The purpose of this study is to review our method of flap selection in cases of total glossectomy defects with laryngeal preservation, with an emphasis on the variations of these defects and patient body habitus. The abdominal ultrasonography and hepatic MRI detected a heterogeneous mass in the spleen measuring approximately 5 cm in diameter. Human T-lymphocytes are long lived, easily accessible, mature, and capable of proliferation.

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The aldolase substrate and other compounds that bind to the active site inhibit its interaction with TRAP and with F-actin, suggesting that the function of the motor is metabolically regulated. The antiestrogen tamoxifen impedes this association suggesting that the latter would play an important role in CaM-dependent enzymatic catalyses. In particular, the number of samples may be smaller than the dimensions of the response. For over 40 years transport safety researchers have been using methods of vehicle instrumentation to gain greater insights into the factors that contribute to road user crash risk and the associated crash factors. Comparison of the FDA-approved CDC DENV-1-4 real-time reverse transcription-PCR with a laboratory-developed assay for dengue virus detection and serotyping. Experiments employing C2-, C3-, or C7-depleted serum demonstrated that C3 activation via the alternative pathway is crucial for potent GBS-induced TNF-alpha release.

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Several studies now support outpatient treatment of many serious bacterial infections in children, such as periorbital or buccal cellulitis, urinary tract infection, pneumonia, and abscess. Evaluation provides valuable feedback to assess the comprehensiveness of existing tools and the need for change. Enhanced oral delivery of paclitaxel using acetylcysteine functionalized chitosan-vitamin E succinate nanomicelles based on a mucus bioadhesion and penetration mechanism. Overexpression of either protein in a mouse pro-B cell line, Ba/F3, and a human leukemia cell line, Jurkat, inhibited G(1) to S phase progression through suppression of retinoblastoma protein (Rb) phosphorylation. Clinical significance of serum total and heat-stable alkaline phosphatase in leukemia patients. The failure of somatostatin to inhibit insulin secretion in pancreatic islets may be due to alterations in the beta cells produced by the isolation procedure. We have characterized three cis-acting elements of the human CYP11A1 gene. These results are the first to indicate that CLCP1 plays a role in cell motility, whereas they also showed that at least one of its ligands is SEMA4B and that their interaction mediates proteasome degradation by CLCP1. Topical mitomycin C (MMC) has been recently used in the management of resistant strictures. Role of phosphorylation of myosin and actin-binding proteins in endothelial permeability induced by thrombin.

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