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Lasix (Furosemide)
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Lasix

Lasix is in a class of medications called diuretics (water pills). It works by causing the kidneys to get rid of unneeded water and salt from the body into the urine. Lasix is used alone or in combination with other medications to treat high blood pressure. Lasix is used to treat edema (fluid retention; excess fluid held in body tissues) caused by various medical problems, including heart, kidney, and liver disease.

Other names for this medication:
Aldalix, Anfuramide, Ansemid, Betasemid, Foliront, Frusemide, Frusenex, Furantral, Furesis, Furetic, Furide, Furocot, Furosemide, Furovet, Furoxem, Furozenol, Fursemid, Furtenk, Fusix, Inclens, Intermed, Jufurix, Lasilacton, Lasilactone, Lasiletten, Lasilix, Salix, Vesix

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Also known as: Furosemide

Description

Furosemide injection is used to help treat fluid retention (edema) and swelling that is caused by congestive heart failure, liver disease (cirrhosis), kidney disease, or other medical conditions.

Furosemide belongs to a group of medicines called loop diuretics or "water pills". It works by acting on the kidneys to increase the flow of urine.

This medicine is to be given only by or under the direct supervision of a doctor.

Dosage

Lasix is available in tablets which should be taken orally with a full glass of water. The dosage of Lasix depends on the body weight and on the health status of the recipient. Take Lasix at the same time once a day. Do not take more than your recommended dose, as high doses of furosemide may cause irreversible hearing loss. Do not crush or chew the tablet. To achieve the most effective results, do not stop taking Lasix suddenly.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include feeling very thirsty or hot, heavy sweating, hot and dry skin, extreme weakness, or fainting.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Lasix are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Excessive diuresis may result in dehydration and reduction in blood volume with circulatory collapse and with the possibility of vascular thrombosis and embolism, particularly in elderly patients.

Excessive loss of potassium in patients receiving cardiac glycosides may precipitate digitalis toxicity.

In patients with hepatic cirrhosis and ascites, initiation of therapy with Lasix is best carried out in hospital. Sudden alterations of fluid and electrolyte balance in patients with cirrhosis may precipitate hepatic coma, therefore, strict observation is necessary during the period of diuresis.

Cases of reversible or irreversible tinnitus or hearing impairment have been reported. Usually, reports indicate that Lasix ototoxicity is associated with rapid injection or infusion, severe renal impairment, hypoproteinaemia, doses exceeding several times the usual recommended dose, or concomitant therapy with aminoglycoside antibiotics, ethacrynic acid, or other ototoxic drugs. In patients with hypoproteinaemia, e.g. associated with nephrotic syndrome, the effect of Lasix may be weakened and its ototoxicity potentiated. Cautious dose titration is required. If the physician elects to use high dose parenteral therapy, controlled intravenous infusion is advisable (for adults with normal renal function, an infusion rate not exceeding 4 mg Lasix per minute must be used; for adults with impaired renal function, an infusion rate of no greater than 2.5 mg per minute must be used).

Caution should be exercised when administering curare or its derivatives to patients undergoing frusemide therapy. It is also advisable to discontinue frusemide for one week prior to any elective surgery.

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Spinal epidural lipomatosis (SEDL) is a rare disorder often associated with the administration of exogenous steroids or the elevation of endogenous steroids. Comparison of the EcoRII methylase sequence with other cytosine methylases revealed several domains of partial homology among all cytosine methylases. Male somatizers differed from male nonsomatizers by showing greater disease conviction and affective disturbance and more readiness to acknowledge difficulties in their lives other than health problems. This, together with loss of data due to movement artefact, makes this technique unreliable in quantifying the sympathetic response to a noxious stimulus in preterm infants. The presented graphical representation is available for visualizing characterizations of a single DNA sequence and identifying similarities and differences among several DNAs. Mouse models of HS include spontaneous inherited hemolytic anemias and those generated by gene targeting. Double cancer of the lung and renal pelvis is very rare and our case seems to be the 7th in the Japanese clinical literature.

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The equilibrium for the binding reaction between the 30 S and 50 S ribosomal subunits of E. These studies were performed using two experimental models, porcine skin and human skin. Parathelphusa pardus, a new species of lowland freshwater crab from swamps in central Sumatra, Indonesia (Crustacea: Brachyura: Gecarcinucidae). The physicochemical properties of MWCNT/TiO2 nanocomposite thin films, including composition and photocatalytic activity, can be varied by changing the concentration of AOT during assembly. Absorption of the sst2A antibody with the receptor peptide abolished specific staining in both immunoblots and tissue sections (negative control). This case highlights the importance of repeat imaging in patients with symptoms concerning for vestibular schwannoma who might have previously undergone negative scans. We present a hypothesis, based upon results obtained from our laboratory and others, on the nature of progression of prostate cancer cells and their predilection to growth and metastasis in the bone microenvironment. Furthermore, affected individuals in four consanguineous recessive pedigrees with AI but without CRD were heterozygous at this locus, excluding it as a common cause of non-syndromic recessive AI. Amassed evidence from several randomized controlled trials and high quality meta-analyses clearly support the primary use of paclitaxel-coated balloons (PCB) in the superficial femoral artery over traditional plain balloon angioplasty or primary bare nitinol stenting with significantly lower vascular restenosis, less need for repeat procedures, improved quality of life and potential cost savings for the healthcare system.

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After we controlled for the confounding variable of concurrent use of other drugs, the increased risk for SIDS could not be attributed to intrauterine cocaine exposure alone. We present evidence for light triggered membrane permeabilization in the presence azobenzene-modified polymers (AMPs). We present our evolution methods in terms of a network statistics differential notation. The modalities of administration of sublingual immunotherapy (SLIT), including dosing, build-up phase, duration of the treatment, and frequency of the maintenance dose are largely variable. Our results indicate that not only p-ANP but also serum ACE activity was markedly increased in experimental hyperthyroid rabbits.

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