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Ginkan (Metronidazole)

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Ginkan belongs to the class of medicines known as antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.

Other names for this medication:
Acuzole, Amebidal, Amevan, Amotrex, Anamet, Biatron, Biozyl, Birodogyl, Efloran, Entizol, Flagemed, Flagolin, Flagystatine, Fortagyl, Gynomix, Lindoplus, Medazol, Metrajil, Metrin, Metronex, Metronid, Metronidazolum, Metroson, Metsina, Nidazol, Nidazole, Noritate, Norzol, Orogyl, Pharmaflex, Riazole, Rosalox, Rozacrme, Rozamet, Stomorgyl, Torgyl, Trichex, Tricozyl, Trikozol, Vagizol, Zidoval

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Also known as: Metronidazole


Metronidazole is used to treat bacterial infections in different areas of the body. The extended-release tablets are used to treat women with vaginal infections (bacterial vaginosis).

Metronidazole belongs to the class of medicines known as antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain metronidazole. It may not be specific to Ginkan ER. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

The capsules can be taken with or without food. If the medicine upsets your stomach, it is best to take it with a meal or snack.

The extended–release tablet must be taken without food, 1 hour before or 2 hours after a meal.

Swallow the extended-release tablet whole. Do not break, crush, or chew it.

To help clear up your infection completely, keep using this medicine for the full time of treatment, even if you begin to feel better after a few days. If you stop using this medicine too soon, your infection may return.

This medicine works best when there is a constant amount in the blood. To help keep the amount constant, do not miss any doses. Also, it is best to take the doses at evenly spaced times during the day. If you need help planning the best times to take your medicine, check with your doctor.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage forms (capsules or tablets): For amebiasis infections: Adults—500 or 750 milligrams (mg) 3 times a day for 5 to 10 days. Children—Dose is based on body weight and must be determined by your doctor. The dose is usually 35 to 50 milligrams (mg) per kilogram (kg) of body weight per day, divided into 3 doses, for 10 days. For bacterial infections: Adults—Dose is based on body weight and must be determined by your doctor. The dose is usually 7.5 milligrams (mg) per kilogram (kg) of body weight every 6 hours for 7 to 10 days. Your doctor may increase your dose as needed. However, the dose is usually not more than 4000 mg per day. Children—Use and dose must be determined by your doctor. For trichomoniasis infections: Adults—The tablet can be given 3 different ways: as a single dose of 2 grams, as 1 gram 2 times a day for 1 day, or as 250 milligrams (mg) 3 times a day for 7 days. The capsule dose is 375 mg 2 times a day for 7 days. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): For bacterial vaginosis: Adults—750 milligrams (mg) once a day for 7 days. Children—Use and dose must be determined by your doctor.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include nausea, vomiting, and loss of balance or coordination.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Metronidazole topical dosage information

Side effects

The most common side effects associated with Ginkan are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Appropriate studies have not been performed on the relationship of age to the effects of metronidazole injection in the pediatric population. Safety and efficacy have not been established.

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Its mechanism of action or adenylate cyclase was determined and found to be chiefly directed against the catalytic subunit. Repeat hepatic resections seem to improve prognosis and are recommended in patients with recurrent metastases confined to the liver. The major phospholipases in myocardium belong to a family of proteins known as calcium-independent phospholipases (iPLA2s). Association of glutathione S-transferases M1 and T1 gene polymorphisms with the risk of metabolic syndrome in an Iranian population. These data suggest that 5HT availability is reduced in menstrual migraine, possibly due to an increased catabolism and/or to a reduced synthesis, and hence predisposes patients to migraine attacks. Instead, all of these inhibitors induce a conformational change in Glu371, creating an active site with altered molecular recognition properties.

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These results indicate that protein kinase C possibly mediates some of the actions of TPA, such as the inhibition of differentiation and metabolic cooperation, but not that of the promotion of in vitro transformation. Only one small prospective, descriptive study without control has been conducted in relation to idiopathic toe walking and sensory processing. The development of custom-made bioreactors for use as a bioartificial liver (BAL) is considered to be one of the last challenges on the road to successful temporary extracorporeal liver support therapy. A natural variant of bovine dopamine beta-monooxygenase with phenylalanine as residue 208: purification and characterization of the variant homo- and heterotetramers of (F208)4 and (F208)2(L208)2. Making treatment decisions with HIV infection: a pilot study of patient preferences.

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Why epigenetics is not a vindication of Lamarckism - and why that matters. Soluble dipeptidyl peptidase IV (CD-26) in serum of patients with colorectal carcinoma. Ours is however the first report documenting the occurrence of these symptoms at the onset of the disease in an autopsy proven case of rabies. Twenty self-paired serum samples were collected from 9 advanced NSCLC patients that evaluated as disease control (SD or PR) after gefinitib therapy, at the time points of before and after gefinitib treatment but 2 weeks before being evaluated as disease progress. The proposed risk-adapted strategy for both centrally and peripherally located lesions showed an acceptable toxicity profile while maintaining excellent local control rates. This study examines spontaneously reported health goals and their characteristics in a sample of 557 American adults. This finding is not surprising given the low local Reynolds number environment within which the antenna operates, and points to striking similarities between the copepod antenna motion and ciliary propulsion. These prospective data suggest that use of estrogen-progestin replacement therapy imparts an increased risk of breast cancer in comparison with never use of PMH. Here we investigated why different PKC agonists had opposing effects on cell proliferation. Case 2:A 78-year-old woman with a subarachnoid hemorrhage due to a ruptured small left middle cerebral artery aneurysm underwent successful coil embolization.

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In vitro experiments show that FleQ binds to lapA and bcs promoter DNA. Age-related brain diseases may in part be related to loss of neural plasticity. The aim of the present study was to determine the effects of culture on caregiver psychological morbidity among informal caregivers of institutionalised persons with dementia in three different populations: (1) Shanghai, (2) Australian-Chinese and (3) Australian mainstream (non-Chinese). A 20-epi side chain restores growth-regulatory and transcriptional activities of an A ring-modified hybrid analog of 1 alpha, 25-dihydroxyvitamin D3 without increasing its affinity to the vitamin D receptor. Complete blood, biochemical and instrumental examinations resulted in findings within normal range. On the other hand, there is no effective intervention for liver metastasis accompanying pancreatic cancer, as small lesions of multiple liver metastases progress rapidly. Synthesis and expression of genes encoding putative insect neuropeptide precursors in tobacco.

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The expression of c-met protein was detected by western blot in HBx-transfected HepG2 cells, the human c-met promote activity was checked by luciferase assay using five different constructs with deletion or point mutation. The results suggest that the cAPK-binding domain of PKI alpha extends from the its N-terminus to residues beyond Ser28 but does not include the segment around Ser59, which is still part of a highly flexible domain when bound to the C-subunit. The diversity of the isolates within the pairs therefore suggests rapid reinfection within the partnerships. Thin-section computed tomography (CT) of the lungs was introduced more than 20 years ago and has an established role in the assessment of patients who are known to have, or are suspected of having, diffuse lung disease. In human prostate cancer, the presence of both these aberrations may be indicative of poor prognosis, suggesting that preclinical therapeutic research should target both of these pathways. Depressed patients were not different from the healthy controls with regard to OCT parameters. Here we examined the amount of light transmitted through and reflected off the wing membranes of four species of live pteropodid bats. A strong correlation was also observed between peptide-Ld affinity and the ability of peptides to sensitize Ld target cells for lysis by CTL 2C. The results were then put into the tables established according to the ISTH (International Society on Thrombosis and Hemostasis).

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We reviewed 211 MCA aneurysms that received EVT between January 2012 and December 2014. Shahrekord University of Medical Sciences supported this research (project no. The metastable orange crystals of HgI(2) comprise three different crystal structures all of which are built from corner-linked Hg(4)I(10) supertetrahedra. New three-dimensional QEEG imaging methods offer an economical alternative to other functional brain imaging modalities. Herd behavior is common in situations in which consumers infer product quality from other consumer choices and incorporate that information into their own decision making. Pharmacokinetics and pharmacodynamics of MX2 hydrochloride in patients with advanced malignant disease. The findings reported here reveal that for multilocalized proteins, consideration of the spatiotemporal distribution may be crucial for understanding viral protein behavior and function.

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One hundred seventy-one preperimetric glaucoma VFs (PPGVFs) from 53 eyes in 51 OAG patients and 108 healthy eyes of 87 healthy participants. Here, we present the virion structure of an Aparavirus, Israeli acute bee paralysis virus (IAPV), a member of a complex of closely related viruses that are distributed worldwide. Adaptative disorders need both psychotherapy and psychopharmacotherapy. These results suggest that PON2, PON3 mRNA levels were not changed significantly in placentae of IUGR when compared to normal pregnant women. Cancer of the uterine cervix: a sexually transmitted viral disease. This cross-sectional study was performed on 112 consecutive patients with CAD (28 nonalbuminuric patients without diabetes, 40 nonalbuminuric patients with type 2 diabetes, and 44 albuminuric patients with type 2 diabetes) and 30 consecutive patients with no CAD, no diabetes, and no albuminuria. Whether it could improve their delivery into the central nervous system remains to be explored. We are reporting a case, and bringing forward some biological, epidemiological and clinical characteristics.

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A cross-sectional study was designed and the BREAST-Q outcomes assessment instrument was used to evaluate patient-reported psychosocial, physical and sexual well-being, as well as satisfaction with breasts, overall outcome and process of care. The most significant improvements were found concerning PI in CHX solution with SRP and CHX gel with SRP groups over controls at one month recall, as well as concerning BI and PPD in CHX chip with SRP group over SRP alone at three-month recall. All discussions were transcribed verbatim, and analysed independently by the two authors according to the principles of thematic analysis. This suggests that the drug has prolonged effect and capacitate the treated rats for improved sexual potential. As its predecessor, LSDI, DLSDI is insensitive to motion artifacts and it can be used on conventional MR scanners. Previous studies have shown that all-trans-retinoic acid (RA) inhibits in vitro proliferation of hormone-dependent human breast cancer cells but not the growth of hormone-independent cells.

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Composite transposons Tn5 and Tn10 in Escherichia coli K12: precise excision and recombination. The orbitofrontal/cingulate region had low gray matter volume in elderly schizophrenia patients. Primary follicular thyroid carcinoma metastasis to the kidney and widespread dissemination: A case report. Macroscopically the basidiocarps of the Hungarian strains are absolutely identical with those of described previously about the Ganoderma lucidum species-complex. Anti-labyrinthine antibodies in a patient with relapsing polychondritis. Results demonstrated a statistically significant reduction in the overall rate of complications, length of hospital stay and duration of postoperative drainage for patients who underwent uniportal VATS lobectomy. The Bacteroides by-product succinic acid inhibits neutrophil respiratory burst by reducing intracellular pH.

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Congenital lesions were present in 57 patients, either at pediatric (27 patients) or adult age (30 patients). Pediatric respiratory papillomatosis: prognostic role of viral typing and cofactors. Reoperation for right ventricular outflow tract obstruction after arterial switch operation for transposition of the great arteries and aortic arch obstruction. Plasma cell neoplasia was suspected on the basis of these findings. To determine the frequency, associated factors and relationship with vulvovaginal symptoms and vaginal douching among Turkish women. The effective area of anode and the proton exchange membrane had a significant effect on the performance of MFCs. The inhibition of proliferation of transformed cells by transfection with DNA from normal cells may be a useful method for cloning onco-suppressor genes. Dialyzed and nondialyzed uremic patients had higher bcl-2 protein concentrations than healthy subjects compazine . When SOD was incubated with varying amount of DBP the activity of the enzyme was decreased proportionate to the concentration of the phthalates added. Satisfaction with outpatient care is determined by the extent to which the expectations of users are met.

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Complete electrolytic lesions of the ARH destroy ACTH-IR cell bodies as well as fibers in all parts of the brain. Physical and chemical neuroplastic changes occur with learning, memory and chronic pain. The Cdc6p cannot be detected in the mitochondrial or plasma membrane fractions. Fossil taxa do not significantly alter major axes of cranial shape, but they do occupy unique areas of morphospace, change the relative diversity between clades, and fill in notable gaps in primate cranial evolution. Specifically, the following biological questions are addressed: (1) How does this lytic virus panadol advance 500mg tablet survive in the nervous system and why can it establish a lifelong latent infection in nerve cells?. Poor physical function rather than poor mental function independently predicts greater use of acute health care resources in adults with sickle cell disease.

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One of them, Stathmin 1, which is involved in the microtubule system, was highly expressed in high-stage tumors compared with the low-stage tumors. Correlation and risk factors between vascular endothelial dysfunction and erectile dysfunction. The aim of the study was to compare Cx43 expression in primary colorectal tumors of patients with stage III and can i overdose on cymbalta IV disease. Systemic steroid for chronic otitis media with effusion in children. In contrast, the mercaptoalkanoyl chain of CoB(6)SH adopts a different conformation, such that its thiolate is coincident with the position of the CoBSH thiolate. If variation in synaptic and behavioral phenomena is found, correlation between these traits may be investigated. Strategies to inhibit viral protein nuclear import: HIV-1 as a target.

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A cross-sectional, anonymous mailed survey was taken of EPs in the state of Oregon. The in vitro autoradiography and ligand binding studies indicate that canine insulinomas express one type of SSTR. Recent inspection of morphological variation in adults and larvae suggests that the taxon comprises three regional populations: eastern, northern and western that may each represent separate species. A survey of the respiratory health of silica-exposed gemstone workers in Hong Kong. In orbital trauma, there is debate about the optimal timing of repair, preferred biomaterial to be used, and the utility of evaluation afterward with intraoperative computed tomographic scan. These methods avoid the impracticable full search for optimal variables in large sets of molecular descriptors. A colony was generated by crossing carrier females with normal males. Resveratrol protects the ovary against chromium-toxicity by enhancing endogenous antioxidant enzymes and inhibiting metabolic clearance of estradiol. Management of the rheumatoid hindfoot with special reference to talonavicular arthrodesis.

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These dynamic properties of ER-NE calcium stores provide insights into the spatiotemporal control of calcium signaling. A quantitative theory of noise adaptation in stochastic integrate-and-fire neurons is developed. Lateral and fourth ventricular GLP-1 resulted in reduction of food intake at similar doses, whereas only lateral ventricular GLP-1 resulted in a CTA. None of the tools is designed to deal with all 10 types of risk. Specific insulin and proinsulin in normal glucose tolerant first-degree relatives of NIDDM patients. To achieve accurate blood pressure measurement through radial artery catheters in infants, we previously developed an experimental high-fidelity catheter-manometer system (CMS). Temperature likely has a direct impact on the initiation of clinging behavior, but it may also serve as cordarone 200 mg 30 scored tablets a simple but reliable indicator of the encounter rate between infected ants and ruminant definitive hosts. Listeria innocua 29-CCM-A 819 (CIP 8011) produces a bacteriocin named Linnocuicina 819.

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The localization of insulinomas is a central problem, because none of the imaging techniques has proved sufficiently reliable for the diagnosis of tumors smaller than 2 cms. Hydrocephalic ferrets developed ventriculomegaly, which was not modified by MgSO4 treatment. Twenty-five patients with duodenal GIST underwent complete resection, local resection (LR) or pancreaticoduodenectomy (PD) from 1990 to 2014 at our 2 hospitals. These results shed light on the diagnosing of the SAR in graphene when subjected to both kinds of SOI. Enhanced urinary angiotensinogen excretion in Cyp1a1-Ren2 transgenic rats with inducible ANG II-dependent malignant hypertension. Scleroderma is a genetically complex autoimmune disease with substantial phenotypic heterogeneity. Furthermore, cocaethylene administration from PDs 4 through 9 produced region-specific alterations in various neurotransmitter concentrations. The rate of influx of serum lipoproteins into the arterial wall is a function of particle size, and will thus be more rapid for small dense LDL.

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In order to identify the virulence determinants within the PICV genome, we developed the molecular clones for both the avirulent P2 and virulent P18 viruses. Treatment was started with spironolactone and an improvement by OCT was shown in all cases. As a possibly more subtle sign of a vasculitic process, complement activation in vessels in ST was studied. By 24 h, this proinflammatory response subsided, and after 4 days, when some bacteria were being degraded, others escaped destruction to replicate within intracellular vacuoles. Alpha rhythm of the parieto-occipital area is comprised of a parade of short-lived cortical excitations (alphons), each of which exhibits oscillations having a stable period within the alpha bandwidth.

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Role of antioxidants in the O-hydroxyethyl-D-(Ser)8-cyclosporine A (SDZ IMM125)-induced apoptosis in rat hepatocytes. When wave localization was abolished, a residual correlation between stimulus directions and response angles remained. If bacterial infectious disease is negative, there is no need for antibacterial chemotherapy. Consequently, the system appears useful for the examination of parameters of nuclear export of HIV-1 and cellular RNAs. This review focuses on the characterization and potential application of MSCs in the regeneration of damaged albenza 200 mg joints. Effect of rotation on the generation of reactive oxygen species in human semen.

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The stress distributions, maximum stresses, and deflections of the miniscrew were evaluated for all parts using ANSYS (Work Bench, 2014). For most of the physical activity scores increases were found in both groups. Giant endometrial cyst of the liver: a case report and review of the literature. Protection against mitochondrial stress in the ocular surface targeting TGM-2 may have important implications in the survival of cells in hyperosmolar stress. Muscle creatine phosphate in gyrate atrophy of the choroid and retina with hyperornithinaemia--clues to pathogenesis.

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