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Eltroxin (Levothyroxine)
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Eltroxin

Eltroxin is a medicine used to treat an underactive thyroid gland (hypothyroidism). The thyroid gland makes thyroid hormone which helps to control energy levels and growth. Eltroxin is taken to replace the missing thyroid hormone.

Other names for this medication:
Eltroxin, Levothyroxine, Levoxyl, Roxin, Synox, Synthroid, Thyronorm, Thyrosec, Thyrowin, Thyrox, Unithroid

Similar Products:
Lunesta, Phenergan, Zyrtec, Sumycin, Lipitor, Combivent, Noroxin, Chloromycetin, Aristocort, Pramace, Syziral, Levoking, Andial, Pranol, Clonate, Cordafen, Opratab, Ceello,

Also known as: Levothyroxine

Description

Levothyroxine is used to treat hypothyroidism, a condition where the thyroid gland does not produce enough thyroid hormone. Levothyroxine is also used to help decrease the size of enlarged thyroid glands (also called a goiter) and to treat thyroid cancer.

This medicine is available only with your doctor's prescription.

Dosage

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

  • For oral dosage form (capsules):
    • For hypothyroidism:
      • Adults and children older than 12 years of age (growth and puberty complete)—Dose is based on body weight and must be determined by your doctor. The dose is usually 1.7 microgram (mcg) per kilogram (kg) of body weight per day but may be less in older adults.
      • Children older than 12 years of age (growth and puberty incomplete)—Dose is based on body weight and must be determined by your doctor. The dose is usually 2 to 3 mcg per kg of body weight per day.
      • Children 6 to 12 years of age—Dose is based on body weight and must be determined by your doctor. The dose is usually 4 to 5 mcg per kg of body weight per day.
      • Children younger than 6 years of age—Use is not recommended as your child might not be able to swallow the capsules.
    • For thyroid cancer:
      • Adults—Dose is based on body weight and must be determined by your doctor. The dose is usually more than 2 microgram (mcg) per kilogram (kg) of body weight per day.
      • Children—Use and dose must be determined by your doctor.
  • For oral dosage form (solution):
    • For hypothyroidism:
      • Adults and children older than 12 years of age (growth and puberty complete)—Dose is based on body weight and must be determined by your doctor. The starting dose is usually 1.7 microgram (mcg) per kilogram (kg) of body weight per day. Your doctor may adjust your dose as needed.
      • Children older than 12 years of age (growth and puberty incomplete)—Dose is based on body weight and must be determined by your doctor. The dose is usually 2 to 3 mcg per kg of body weight per day.
      • Children 6 to 12 years of age—Dose is based on body weight and must be determined by your doctor. The dose is usually 4 to 5 mcg per kg of body weight per day.
      • Children 1 to 5 years of age—Dose is based on body weight and must be determined by your doctor. The dose is usually 5 to 6 mcg per kg of body weight per day.
      • Children 6 to 12 months of age—Dose is based on body weight and must be determined by your doctor. The dose is usually 6 to 8 mcg per kg of body weight per day.
      • Children 3 to 6 months of age—Dose is based on body weight and must be determined by your doctor. The dose is usually 8 to 10 mcg per kg of body weight per day.
      • Children 0 to 3 months of age—Dose is based on body weight and must be determined by your doctor. The dose is usually 10 to 15 mcg per kg of body weight per day.
    • For thyroid cancer:
      • Adults—Dose is based on body weight and must be determined by your doctor. The dose is usually more than 2 microgram (mcg) per kilogram (kg) of body weight per day.
      • Children—Use and dose must be determined by your doctor.
  • For oral dosage form (tablet):
    • For hypothyroidism:
      • Adults and children older than 12 years of age (growth and puberty complete)—Dose is based on body weight and must be determined by your doctor. The dose is usually 1.6 microgram (mcg) per kilogram (kg) of body weight per day but may be less in older adults.
      • Children older than 12 years of age (growth and puberty incomplete)—Dose is based on body weight and must be determined by your doctor. The dose is usually 2 to 3 mcg per kg of body weight per day.
      • Children 6 to 12 years of age—Dose is based on body weight and must be determined by your doctor. The dose is usually 4 to 5 mcg per kg of body weight per day.
      • Children 1 to 5 years of age—Dose is based on body weight and must be determined by your doctor. The dose is usually 5 to 6 mcg per kg of body weight per day.
      • Children 6 to 12 months of age—Dose is based on body weight and must be determined by your doctor. The dose is usually 6 to 8 mcg per kg of body weight per day.
      • Children 3 to 6 months of age—Dose is based on body weight and must be determined by your doctor. The dose is usually 8 to 10 mcg per kg of body weight per day.
      • Children 0 to 3 months of age—Dose is based on body weight and must be determined by your doctor. The dose is usually 10 to 15 mcg per kg of body weight per day.

Overdose

According to the U.S. Prescribing Information, overdoses of Eltroxin up to 90 times the recommended dose have been reported in which the patient fully recovered. According to the May 2014 edition of the official U.S. Prescribing Information, fatalities have been reported only in cases in which eszopliclone was combined with other drugs or alcohol.

Texas poison control centers reported that during 2005–2006 there were 525 total Eltroxin overdoses recorded in the state of Texas, the majority of which were intentional suicide attempts.

If consumed within the last hour, Eltroxin overdose can be treated with the administration of activated charcoal or via gastric lavage.

Storage

Side effects

The most common side effects associated with Eltroxin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

It is very important that your doctor check your progress at regular visits to allow your doctor to see if the medicine is working properly and to decide if you should continue to take it. Blood tests will be needed to check for unwanted effects.

This medicine may increase your risk of heart rhythm problems or heart attack. Check with your doctor right away if you have dizziness, fainting, fast, slow, or irregular heartbeat, chest pain or discomfort, or pain or discomfort in the arms, jaw, back, or neck.

This medicine may cause new or worsening heart failure. Check with your doctor right away if you have more than one of these symptoms: chest pain, decreased urine output, dilated neck veins, extreme fatigue, irregular breathing, irregular heartbeat, swelling of the face, fingers, feet, or lower legs, tightness in the chest, trouble breathing, or weight gain.

Levothyroxine should not be used for the treatment of obesity or for the purpose of losing weight. This medicine is ineffective for weight reduction and when taken in larger amounts may cause more serious medical conditions.

Make sure any doctor or dentist who treats you knows that you are using this medicine. This medicine may affect the results of certain medical tests.

Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.

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A highly active soluble peroxidase has been identified in the preputial glands of the rat. The large number of genes detected with class I probes by Southern blot analysis and the existence of serological reagents defining nonubiquitous, non-HLA-A,B,C class I antigens suggest that products other than HLA-A,B,C antigens are encoded within the class I gene family. The current study demonstrates that functional excitatory connectivity originating from non-primary motor areas is compromised in multiple sclerosis patients even in the absence of clinical disability. Different bacteria were recovered from a few samples but did not seem significant. A 1-year prospective trial was completed on a walking circuit with two integrated force platforms and an optoelectronic system for three-dimensional movement analysis. A group of 14 has been trained with their lower limbs (LL), while another similar group of 14 patients was also trained with their upper limbs (UL). We will discuss their charge transport, controlled by electrochemical gates, interfacial and quantum capacitance, charged impurities, and surface potential distribution. Results suggest that different recognition events are involved in the expression of resistance to the two fungi used or that C.

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A 40-year-old man had been followed in the pulmonary clinic for prolonged cough. Development of a multiple sclerosis functional composite as a clinical trial outcome measure. Recommendations of the Immunization Practices Advisory Committee. Single-Molecule FRET States, Conformational Interchange, and Conformational Selection by Dye Labels in Calmodulin. This pattern suggested that at least one autoantigen of PCD may be a glycoprotein specific cerebellar tissue that is associated with the endoplasmic reticulum. Neonatal infections are the commonest causes for neonatal blistering. Prognostic implications of different cell cycle analysis models of flow cytometric DNA histograms of 1,301 breast cancer patients: results from the Multicenter Morphometric Mammary Carcinoma Project (MMMCP). Four different conditions were presented: (1) N-H: a neutral face that suddenly changed to a happy face. Since CZE is a separation method, high purity and known concentration for the samples is not necessary because only mobilities are measured. The expression of STAT1 and STAT5 in a human T-cell line was induced by Tax.

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Flow-mediated dilatation (FMD) of the peripheral arteries may be impaired in chronic heart failure (CHF), and this could contribute to the increased peripheral resistance and exercise intolerance that occur with this disease. Northern and Western blot analyses of cell lines, as well as immunostaining of tissue sections from the original tumor surgical samples, confirmed that MRP1/CD9 was highly expressed at the primary site, compared to the low levels of expression in metastases. An orchiectomy had been accomplished on the right side, with confirmation of cysts of the tunica albuginea. In the present study the presence of laminin and heparan sulphate proteoglycan, another ECM molecule, on CNS glial (astrocytes) and non-glial (leptomeningeal) cells in vitro was examined. CysC had significant associations with both creatinine and SUA in Japanese junior high school students. Structure-activity relationships gained from these studies have aided in the synthesis of D2 partial agonists of varying intrinsic activity levels. RT-PCR was used to examine the expression of LAR (encoding the leukocyte-common antigen-related protein danocrine tyrosine phosphatase) in normal human colon mucosa, and colon polyps and tumors. Pedal fat grafting significantly improves pain and disability outcomes, and prevents against worsening foot pressures. Since PACAP depresses a C-fibre evoked flexion reflex, this may have implications for sensory transmission.

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