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Eldepryl

Eldepryl is used to help control the symptoms of Parkinson's disease. Eldepryl belongs to a group of drugs called monamine oxidase (MAO) inhibitors. They affect levels of certain natural substances in the brain. These substances are involved with motor control.

Other names for this medication:
Elegelin, Emsam, Jumax, Jumex, Selegiline, Selerin, Selgin, Zelapar

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Also known as: Selegiline

Description

Selegiline is used in combination with levodopa or levodopa and carbidopa combination to treat Parkinson's disease (sometimes called "shaking palsy" or "paralysis agitans"). This medicine works to increase and extend the effects of levodopa, and may help to slow the progress of Parkinson's disease.

This medicine is available only with your doctor's prescription.

Dosage

Take Eldepryl orally. Take Eldepryl capsules twice a day, at breakfast and lunch. Do not swallow the tablet whole. Allow it to dissolve in your mouth without chewing. Do not drink or eat anything for at least 5 minutes after takink Eldepryl. While using Eldepryl, you must not eat foods that are high in tyramine such as air dried meats, aged or fermented meats, sausage or salami (including cacciatore and mortadella), pickled herring, and any spoiled or improperly stored beef, poultry, fish, or liver; beer from a tap, beer that has not been pasteurized; aged cheeses, including blue, boursault, brick, brie, camembert, cheddar, emmenthaler, gruyere, parmesan, romano, roquefort, stilton, and swiss; sauerkraut, soy beans, soy sauce, tofu, miso soup, bean curd, fava beans; yeast extracts (such as Marmite). Preferable food during Eldepryl usage are fresh meat, poultry, or fish (including lunch meat, hot dogs, breakfast sausage, and cooked sliced ham); any vegetables except broad bean pods (fava beans); processed cheese, mozzarella, ricotta, cottage cheese; pizza made with cheeses low in tyramine; soy milk, yogurt. If you want to achieve most effective results do not stop taking Eldepryl suddenly.

Overdose

If you overdose Eldepryl and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Eldepryl overdosage: severe headache, hallucinations, vision problems, sweating, cool or clammy skin, fast or uneven heart rate, feeling light-headed, fainting, seizure.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Eldepryl dosage information

Side effects

The most common side effects associated with Eldepryl are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Eldepryl if you are allergic to Eldepryl components. Do not take Eldepryl if you are pregnant, planning to become pregnant or breast-feeding. Be careful using Eldepryl if you have kidney disease, liver disease, heart disease, high or low blood pressure, seizure disorder. Be careful using Eldepryl if you take over-the-counter medications you use, including vitamins, minerals, and herbal products, carbamazepine (Tegretol), diet pills or cold medicines that contain ephedrine, pseudoephedrine or phenylephrine, nafcillin (Unipen), phenobarbital (Luminal, Solfoton), rifampin (Rifadin, Rifater, Rifamate, Rimactane), antidepressants such as amitriptyline (Elavil), amoxapine (Ascendin), bupropion (Wellbutrin, Zyban), citalopram (Celexa), clomipramine (Anafranil), desipramine (Norpramin), doxepin (Sinequan), duloxetine (Cymbalta), escitalopram (Lexapro), fluoxetine (Prozac), fluvoxamine (Luvox), imipramine (Tofranil), nortriptyline (Pamelor), paroxetine (Paxil), protriptyline (Vivactil), sertraline (Zoloft), venlafaxine (Effexor) or trimipramine (Surmontil). While using Eldepryl, you must not eat foods that are high in tyraminesuch as air dried meats, aged or fermented meats, sausage or salami (including cacciatore and mortadella), pickled herring, and any spoiled or improperly stored beef, poultry, fish, or liver; beer from a tap, beer that has not been pasteurized; aged cheeses, including blue, boursault, brick, brie, camembert, cheddar, emmenthaler, gruyere, parmesan, romano, roquefort, stilton, and swiss; sauerkraut, soy beans, soy sauce, tofu, miso soup, bean curd, fava beans; yeast extracts (such as Marmite). Do not take Eldepryl if you use over-the-counter supplements or cough and cold medicines that contain tyramine. It can be dangerous to stop Eldepryl taking suddenly.

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PET/CT with Fluorodeoxyglucose During Neoadjuvant Chemoradiotherapy in Locally Advanced Rectal Cancer. Pancreatic duct cannulation rates exceeded those of the common bile duct. In addition, the advantage, current issue and prospect of using circulating DNA as tumor marker are also analyzed. The new findings, the background for the ongoing debate on stress-induced mutagenesis, and the phenotypic heterogeneity underlying a novel phage infection strategy are discussed in this short manuscript. Special attention has been paid to the problems concerning representativeness for muscle blood flow (muscle vs other tissues and small muscle segments vs skeletal musculature of the total body) as well as the demand for steady state. The design of the optical pathway is discussed, and some design rules and simulation results are presented. The indications, technique, and complications of endoscopic sphincterotomy are covered in detail in this article. Asthma is a heterogeneous disease that can be classified into different clinical endotypes, depending on the type of airway inflammation, clinical severity, and response to treatment. The results showed that the process of disinfection performed is not consistent with recommendations by the Health Department and/or State Health Secretariat, and that the personnel involved in this activity has incomplete knowledge of the standardization of the use of the chemical products utilized and of the conditions that interfere with their action during the disinfection process.

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The Manne Dora, a small tribe inhabiting the north coastal districts of Andhra Pradesh, South India, have been studied for 24 genetic markers, including blood groups, plasma proteins, and red cell enzymes. A poroid neoplasia arising close to a seborrheic keratosis and a trichoepithelioma. Rucaparib is a potent Poly (ADP-ribose) Polymerase (PARP) inhibitor currently under clinical development. The incidence of serious trocar accidents was evaluated from a retrospective French study of 103,852 laparoscopic operations involving almost 390,000 trocars. Respiratory syncytial virus infects the Bonnet monkey, Macaca radiata. Addition of both CTX and PTX additionally inhibited mPL-I secretion but did not affect mPL-II secretion. The characterization studies confirmed that the DG-2 monoclonal antibody recognised beta-FGF and inhibited its mitogenic action on mouse Balb/c cells and bovine endothelial cells in vitro.

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Experiments covering both personal and static sampling and a range of sampler types were carried out in the laboratory for both fibrous asbestos and isometric silica gel dusts. Spatiotemporal distribution of chondroitin sulfate proteoglycans in the developing mouse retina and optic nerve. ACTICOAT dressing killed the bacteria that were tested much faster, which is a very important characteristic for a wound dressing acting as a barrier to invasive infection to have. The molecular mechanisms underlying the formation of the thalamus during development have been investigated intensively. The observed performance is in good agreement with the theoretical signal and noise level predictions. Outcome after treatment of neurological decompression illness is predicted by a published clinical scoring system. Rabbit antisera against poliovirus strains 3844, Sabin-1, Mahoney and Brunhilde were produced. DNA restriction analysis with seven endonucleases showed about equal genetic distance from both AV3 and 7 prototypes.

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Over 45,000 new cases of oral and pharyngeal cancers are diagnosed and account for over 8,000 deaths a year in the United States. Inotropic support, pericardectomy, and implantation of a left ventricular assist device were required for maternal survival. MMP-9 gene expression and proteolytic activity were measured using qPCR and zymography, respectively. We performed a retrospective chart review of 11 patients with DOCK8 deficiency and measured DOCK8 expression and cytokine production. Very good correlation was seen between the Xpert HIV-1 VL and Abbott RealTime HIV-1 assays, with added benefits for Xpert HIV-1 VL of: (1) lot-to-lot consistency traceable to WHO International Standard, (2) requiring both high and low level internal controls to be in range to have a valid result, (3) use of a single HIV-1 target for PCR and (4) faster turn-around-time for results, no need to wait to do batch testing of specimens. Quantitative ultrasonic measures of bone quality have been shown to have a predictive capability that is comparable to that of bone density. In vitro transcription assays showed that the mutant RNA polymerase RpoB114 was defective in transcribing the two major promoters of the rpoD operon specifically. A major aim of this paper is to resolve these discrepancies through computations. The number of persons with chronic conditions, their annual direct health care costs, and indirect costs from lost productivity and premature deaths. Drastic decrease of transcription activity due to hypermutated long terminal repeat (LTR) region in different HIV-1 subtypes and recombinants.

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Both intra- and postoperative low number of eosinophils seem to be indicators of good subjective recovery. In overall performance, 5- to 10-year-old children did not differ, but adults outperformed them. The favorable agreement between the refined crystal structure from powder XRD and the NMR parameters is apparent from a convincing correlation between experimental (51)V quadrupole tensor elements and calculated (51)V electric field gradient tensor elements obtained by the point-monopole approach. Results suggest that the equine rotavirus vaccine is safe and immunogenic and that reasonable efficacy under field conditions can be expected. The degree of clustering for common metabolic coronary disease risk factors is not well known, the antecedents of clustering are not well studied, and the impact of such clusters on coronary risk has not been assessed systematically. Both groups had similar improvement in visual acuity and perioperative complications. Results of this study support the validity of the SF-36 to document the health burden of arthritis and as a measure of generic health outcome for clinical trials of alternative treatments for osteoarthritis and rheumatoid arthritis patients.

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Perovskite solar cells (PSCs) based on thin films of organolead trihalide perovskites (OTPs) hold unprecedented promise for low-cost, high-efficiency photovoltaics (PVs) of the future. Transcription from many Escherichia coli promoters can be activated by the cAMP-CRP complex bound at different locations upstream of the promoter. Parents served as proxy respondents for the adolescents by self-administering a validated generic health related quality of life instrument, the Child Health Questionnaire-Parent Form 50. Square-wave voltammetric techniques for determination of psychoactive 1,4-benzodiazepine drugs. It will be argued further that part of the research conducted to date on the symbolic play abilities of children with language impairment has been confounded by the encroachment of language into the research procedures, that the level of play often investigated has not been unquestionably symbolic in nature, and that the actual differences in symbolic play have not been substantial.

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Sensorineural hearing loss in patients treated for nasopharyngeal carcinoma: a prospective study of the effect of radiation and cisplatin treatment. The purpose of this study was to evaluate the clinical outcomes of two-stage reimplantation for infected hip arthroplasty using our protocol of combined parenteral and oral antibiotic therapy and the criterion for reimplantation. In vivo transgene activation from an HSV-based gene therapy vector by GAL4:vp16. We have employed a direct gain-of-function approach using retroviral vectors to misexpress Hoxa2 and Hoxb1 outside of the normal how to stop taking seroquel 25 mg Hox expression domains, thereby avoiding complications resulting from possible interactions with endogenous Hox genes. Current update of hormonal and psychotropic drug treatment of premenstrual dysphoric disorder.

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Familial prostate cancer risk estimates are inflated does flagyl treat bladder infection by clinically insignificant low-risk cancer, diagnosed after prostate-specific antigen testing. These coefficients segregate with specific genotypes including those most frequently observed in human tumors in the clinic. Searching eye movement, smooth pursuit eye movement and schizophrenia. Rabbit auricular chondrocytes were seeded onto the microspheres in vitro to assess their biological performance and applicability as cell carriers. The increased risk of adverse perinatal outcomes associated with prenatal CT infection supports current prenatal CT screening guidelines. Influence of bipolar esophageal electrode positioning on measurements of human crural diaphragm electromyogram.

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Ligand-based active site alignment is a widely adopted technique for the structural analysis of protein-ligand complexes. There is currently no consensus on (1) the percentage of patients who develop spasticity after ischemic stroke, (2) the relation between spasticity and initial clinical findings after acute stroke, and (3) the impact of spasticity on activities of daily living and health-related quality of life. These include alpha-melanotropic hormone, adrenocorticotropic hormone, beta-lipotropic ultram dosage hormone, and beta-endorphin. While the trunk assisted the arm to reach the object, the kinematic parameter recorded did not reveal any evidence of direct coupling. The spherical shape of cells in fibrocartilagenous regions indicates these cells are more loosely attached to the matrix than their spindle-shaped counterparts in fibrous regions, a feature that may help to minimize cell deformation during tendon compression. We present results obtained by applying this methodology to the metabolic network of the plant Arabidopsis thaliana.

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