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Diovan (Valsartan)

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Diovan is used in adults to lower high blood pressure (hypertension), treat heart failure, improve the chance of living longer after a heart attack (myocardial infarction). Diovan is a prescription medicine called an angiotensin receptor blocker (ARB).

Other names for this medication:
Alpertan, Alsart, Alsartan, Arovan, Cardival, Codiovan, Combisartan, Cordinate, Corixil, Cotareg, Diovane, Disys, Dosara, Kalpress, Miten, Nisis, Nisisco, Provas, Ramartan, Rixil, Sarteg, Simultan, Starval, Tareg, Teval, Valaplex, Valcap, Valitazin, Valpresan, Valpress, Valpression, Valsabela, Valsacor, Valsan, Valsaprex, Valsar, Valsartanum, Valtan, Valturna, Valzaar, Valzek, Valzide, Varexan, Vartalan

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Also known as: Valsartan


Hydrochlorothiazide is a diuretic (water pill). Valsartan is an angiotensin II receptor blocker (sometimes called an ARB blocker).

Diovan HCT is a combination medicine used to treat high blood pressure (hypertension). Lowering blood pressure may lower your risk of a stroke or heart attack.

Diovan HCT is given after other blood pressure medicines did not work or have stopped working.


Follow all directions on your prescription label and read all medication guides or instruction sheets. Your doctor may occasionally change your dose. Use the medicine exactly as directed.

You may take Diovan HCT with or without food.

Call your doctor if you have ongoing vomiting or diarrhea, or if you are sweating more than usual. You can easily become dehydrated while taking this medication, which can lead to severely low blood pressure or a serious electrolyte imbalance.

Your blood pressure will need to be checked often. Your blood and urine may also be tested if you have been vomiting or are dehydrated.

If you need surgery, tell the surgeon ahead of time that you are using Diovan HCT.

It may take up to 4 weeks for this medication to control your blood pressure. Keep using this medicine as directed, even if you feel well. High blood pressure often has no symptoms. You may need to use blood pressure medication for the rest of your life.

Store at room temperature away from moisture and heat.

Detailed Diovan HCT dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include fast heartbeats or fainting.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture and heat. Keep your medicine container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Diovan are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use this medicine if you are allergic to valsartan or hydrochlorothiazide, or if you have:

decreased urination or are unable to urinate; or an allergy to sulfa drugs.

If you have diabetes, do not use Diovan HCT together with any medication that contains aliskiren (a blood pressure medicine).

You may also need to avoid taking Diovan HCT with aliskiren if you have kidney disease.

Tell your doctor if you have ever had:

an electrolyte imbalance (such as low levels of potassium or magnesium, or high levels of calcium in your blood); liver disease; kidney disease; gallstones; lupus; congestive heart failure; gout, or high levels of uric acid in your blood; asthma or allergies; high cholesterol or triglyceride levels; an allergy to penicillin; glaucoma; or if you are on a low-salt diet.

Do not use if you are pregnant. Stop using the medicine and tell your doctor right away if you become pregnant. Valsartan can cause injury or death to the unborn baby if you take the medicine during your second or third trimester.

You should not breastfeed while using this medicine.

Diovan HCT is not approved for use by anyone younger than 18 years old.

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Different plasmids carry segments that align to different parts of the blaNDM region found on Acinetobacter plasmids. Despite decreases in radiation dose, no change in the high rate of tumor control has yet been observed. Furthermore, REF6 targets CUP-SHAPED COTYLEDON 1 (CUC1), which harbors CTCTGYTY motifs, to modulate H3K27me3 levels and activate CUC1 expression. Ruptures of the distal biceps tendon are rare injuries which nearly exclusively occur in middle-aged men when eccentric load is applied to the flexed elbow. The perception of the seriousness of a false-negative or false-positive diagnosis could influence treatment decision making for carious lesions. After identifying information was concealed, abstracts were classified independently by two authors into three groups: innovation, modification, or neither. To determine whether an association exists between C-reactive protein (CRP) levels and lower urinary tract symptoms (LUTS) as assessed by the American Urological Association Symptom Index (AUA-SI) among both men and women, and to determine the association of CRP levels with the individual urologic symptoms comprising the AUA-SI among both men and women. Odor coding in a model olfactory organ: the Drosophila maxillary palp. However, few studies use multiple data points and detailed history spanning early adulthood to middle age. Highly efficient Yb:YAG channel waveguide laser written with a femtosecond-laser.

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In cone-beam computed tomography (CBCT) evaluation, an in-ossified suture was found in anterior two-third of midpalatal region of both individuals. Reduced FA with increased lambda(perpendicular) suggests that chronic seizures cause reduction in myelin or decreased axon fiber density in white matter pathways connecting regions of seizure activity. Pharmacological studies on a new antihypertensive agent, S-2150, a benzothiazepine derivative: 1. The diagnosis depends on neurological and neurodevelopmental assessments. The high AC group compared to the low AC group displayed a greater activation in the right IPS and based its calculation more on a feedback driven intraparietal IPS-IPS circuit, whereas the low competence group more on a feedback driven fronto-parietal DLPFC-IPS circuit.

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A case of occupational contact dermatitis caused by N-acetylcysteine. Event-related potentials reveal processing differences in honest vs malingered memory performance. The commonly accepted approach of using only a qualitative test for the diagnosis of factor XIII deficiency is challenged by this case report. This study is the first to define a role for aberrant miR153 contributing to the hypertensive state through targeting of KCNQ4 in an animal model of hypertension, raising the possibility of the use of miR153-related therapies in vascular disease. pylori, has no role in the inflammatory mechanism of acne rosacea. Peptides inhibited the growth of both gram-negative (MIC, 0.08 to 3.00 mM) and gram-positive (MIC, 0.94 to 2.67 mM) bacteria. The green fluorescent protein (GFP)-tagged functional Tax-4 protein is expressed in thermosensory, gustatory, and olfactory neurons mediating all the sensory behaviors affected by the tax-4 mutations. Apelin-induced stimulation of duodenal electrolyte secretion is feeding-dependent and mediated by local mucosal release of CCK. First, to study interaction at uptake, 10 clones with high or low accumulation capacity of Cd, Cu, and Zn, respectively, were treated with 0.3 microM Cd, 0.1 microM Cu, and 3 microM Zn (all three metals at the same time or separately). Saxagliptin and sitagliptin are two commonly used dipeptidyl peptidase-4 (DPP-4) inhibitors.

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To describe a rare case of acute presentation of papillary thyroid carcinoma (PTC). Gel-retardation analysis with GCN4 protein synthesized in vitro has indicated that GCN4 can bind in vitro to at least two of the consensus motifs. The trimerization of E1 is mediated by the sequence-specific binding of E1 to DNA, and results in an E1 complex that is linked topologically to the DNA because the three molecules of E1 form a ring-like structure that encircles the DNA. In this regard, a second receptor which binds selectively to PTH has also been found. As secondary metabolites are typically produced during late growth, potential producers were also allowed 1 to 2 days of growth before exposure to the pathogen. Our aim was to evaluate topographically specific gastric motility changes induced by graded vagal activation. The tumor was successfully removed using a shave excision technique. Potential of Excipient Emulsions for Improving Quercetin Bioaccessibility and Antioxidant Activity: An in Vitro Study. This procedure offers a rapid and simple approach for selecting binders from phage libraries differing in antibody dissociation rate constants.

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Acute Budd-Chiari syndrome: treatment with transjugular intrahepatic portosystemic shunt. There was no significant difference between OA and RA samples in all experiments. The hallmark of the HS response, which is conserved in all eukaryotes, is the rapid and massive induction of expression of a set of cytoprotective genes. The fruit fly, Drosophila melanogaster, is one of the most extensively studied organisms in biological research and has centrioles/basal bodies and cilia that can be modelled to investigate their functions in animals generally. Detection of rRNA from four respiratory pathogens using an automated Q beta replicase assay. With the increased use of blood level screening methods, a large percentage of children in many industrialized countries are being tested as a being at risk.

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The relative importance of the anterior cingulate cortex (ACC) for the detection and resolution of response conflicts versus its role in error monitoring remains under debate. In purified MV fractions, we identified a total of 22 proteins, including five unique protein species that are known to be highly expressed in invasive cancers and participate in cellular activation, metastasis and inhibition of apoptosis. Antioxidant, toxicological and antiproliferative properties of Canadian polyphenolic extracts on normal and psoriatic keratinocytes. Concentrations of both hormones and heart rate increased drug nifedipine er 60 mg side effect in dogs receiving hydralazine monotherapy, and fluid retention was evident. A retrospective study was undertaken of all Chlamydia tests within Waikato District Health Board during February to October 2008. Positioning of patients with intracranial hypertension must be re-evaluated in light of the changing goals of medical management outlined in the critical pathway.

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