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Crestor (Rosuvastatin)
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Crestor

Crestor is used for lower high blood cholesterol levels (hypercholesterolaemia). It contains the active ingredient rosuvastatin calcium. Rosuvastatin calcium belongs to a group of medicines called HMG-CoA reductase inhibitors (also known as 'statins'). This medicine is not addictive. This medicine is available only with a doctor's prescription. There is not enough information to recommend the use of this medicine for children.

Other names for this medication:
Creston, Dorosur, Liparon, Provisacor, Richstatin, Rosumed, Rosuva, Rosuvas, Rosuvast, Rosuvastatin, Rosuvastatina, Rosuvastatinum, Rosuvastin, Rovartal, Rovast, Rozavel, Simestat, Sinlip, Turbovas, Visacor, Zyrova

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Also known as: Rosuvastatin

Description

Crestor (rosuvastatin) belongs to a a group of drugs called HMG CoA reductase inhibitors, or "statins." Rosuvastatin is used together with diet to lower blood levels of "bad" cholesterol (low-density lipoprotein, or LDL), to increase levels of "good" cholesterol (high-density lipoprotein, or HDL), and to lower triglycerides (a type of fat in the blood).

Crestor is used in adults and children who are at least 8 years old to lower cholesterol and triglycerides in the blood.

Crestor is used in adults to slow the progression of atherosclerosis (a build-up of plaque in blood vessels that can block blood flow).

Crestor is used to lower the risk of stroke, heart attack, and certain other heart complications in men 50 years and older and women 60 years and older who have coronary heart disease or other risk factors.

Crestor is also used to treat hereditary forms of high cholesterol, including the heterozygous type (inherited from one parent) and the homozygous type (inherited from both parents). For the heterozygous type, Crestor can be used in children who are at least 8 years old. For the homozygous type, this medicine can be used in children as young as 7 years old.

Dosage

Usual Adult Dose for Hyperlipoproteinemia:

Initial dose: 5 mg to 10 mg once a day with or without food Maintenance dose: 5 mg to 40 mg once a day with or without food

Usual Adult Dose for Hyperlipoproteinemia Type IIa (Elevated LDL):

Initial dose: 5 mg to 10 mg once a day with or without food Maintenance dose: 5 mg to 40 mg once a day with or without food

Usual Adult Dose for Hyperlipoproteinemia Type IIb (Elevated LDL + VLDL):

Initial dose: 5 mg to 10 mg once a day with or without food Maintenance dose: 5 mg to 40 mg once a day with or without food

Usual Adult Dose for Hyperlipoproteinemia Type IV (Elevated VLDL):

Initial dose: 5 mg to 10 mg once a day with or without food Maintenance dose: 5 mg to 40 mg once a day with or without food

Usual Adult Dose for Atherosclerosis:

Initial dose: 5 mg to 10 mg once a day with or without food Maintenance dose: 5 mg to 40 mg once a day with or without food

Usual Adult Dose for Homozygous Familial Hypercholesterolemia:

Initial dose: 20 mg once a day with or without food Maintenance dose: 20 mg to 40 mg once a day with or without food

Usual Adult Dose for Prevention of Cardiovascular Disease:

Initial dose: 5 mg to 10 mg once a day with or without food Maintenance dose: 5 mg to 40 mg once a day with or without food Response to therapy should be estimated from preapheresis LDL-C levels.

Usual Geriatric Dose for Hyperlipidemia:

Initial dose: 5 mg once a day with or without food Maintenance dose: 5 mg to 20 mg once a day with or without food

Usual Pediatric Dose for Heterozygous Familial Hypercholesterolemia:

Pediatric patients 10 to 17 years of age: Usual dose range: 5 to 20 mg orally once a day with or without food. Doses should be individualized according to the recommended goal of therapy. Adjustments should be made at intervals of 4 weeks or more. Maximum dose: 20 mg orally once a day

Detailed Crestor dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Crestor are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Do not take Crestor if you are allergic to Crestor components. Do not take Crestor if you're pregnant or you plan to have a baby, or you are a nursing mother. Be careful with Crestor if you suffer from or have a history of liver, thyroid or kidney disease. Be careful with Crestor if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement. Be careful with Crestor if you have allergies to medicines, foods, or other substances. Do not eat fattening food that is high in cholesterol. Use Crestor with great care in case you want to undergo an operation (dental or any other). Avoid alcohol. Do not stop taking Crestor suddenly.

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Age-related increase of sI(AHP) in prefrontal pyramidal cells of monkeys: relationship to cognition. We subsequently discovered that SMG-1 kinase activity was activated by hypoxia, and depletion of SMG-1 up-regulated MAPK activity under low oxygen. Perceptions of registered and enrolled nurses on thirst in mechanically ventilated adult patients in intensive care units-a phenomenographic study. In the hands of patients, ischemic and enalapril maleate 10 mg fibrotic damages lead to both pain and functional impairment. Median prescribed dose to the paraaortic lymph nodes was 45 Gy (36-50). Numbers of neurons containing an SSB increased progressively in the ischemic core but decreased in the ischemic penumbra after 1 h of reperfusion. Many studies have reported an increased risk of homicide among people suffering from schizophrenia. Eye movement responses to a horizontally moving visual stimulus.

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p53 Loses grip on PIK3CA expression leading to enhanced cell survival during platinum resistance. The CGRP tablet prevented cerebral vasospasm after SAH and may have significant potential for the treatment of patients with SAH. Prevalence of Helicobacter pylori infection in Nicaraguan children with persistent diarrhea, diagnosed by the 13C-urea breath test. Open-label ZDV before ARC or AIDS in the deferred group was likely to have diluted any differences between the immediate and deferred groups. Association of living in a farming environment with asthma incidence in Canadian children.

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