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Cleocin (Clindamycin)
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Cleocin

Cleocin is a strong broad-spectrum antibiotic, typically prescribed for serious infections, such as life-threatening methicillin-resistant Staphylococcus aureus (MRSA) skin infections.

Other names for this medication:
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Also known as: Clindamycin

Description

Cleocin is a prescription medication used to treat bacterial infections of the lungs, skin, blood, bones, joints, female reproductive system, and internal organs.

Cleocin belongs to a group of drugs called lincomycin antibiotics. These work by stopping the growth of bacteria.

This medication is available as a vaginal cream, vaginal suppository, oral capsule, and oral liquid.

This medication is also available in injectable forms to be given directly into a vein (IV) or a muscle (IM) by a healthcare professional.

Common side effects of Cleocin include nausea, vomiting, joint pain, heartburn, pain when swallowing, and white patches in the mouth.

Dosage

This section provides information on the proper use of a number of products that contain clindamycin. It may not be specific to Cleocin T. Please read with care.

Before applying this medicine, thoroughly wash the affected areas with warm water and soap, rinse well, and pat dry.

When applying the medicine, use enough to cover the affected area lightly. You should apply the medicine to the whole area usually affected by acne, not just to the pimples themselves. This will help keep new pimples from breaking out.

You should avoid washing the acne-affected areas too often. This may dry your skin and make your acne worse. Washing with a mild, bland soap 2 or 3 times a day should be enough, unless you have oily skin. If you have any questions about this, check with your doctor.

Topical clindamycin will not cure your acne. However, to help keep your acne under control, keep using this medicine for the full time of treatment, even if your symptoms begin to clear up after a few days. You may have to continue using this medicine every day for months or even longer in some cases. If you stop using this medicine too soon, your symptoms may return. It is important that you do not miss any doses.

For patients using the topical foam form of clindamycin:

After washing or shaving, it is best to wait 30 minutes before applying this medicine. The alcohol in it may irritate freshly washed or shaved skin. This medicine contains alcohol and is flammable. Do not use near heat, near open flame, or while smoking. To apply this medicine: Do not dispense clindamycin topical foam directly onto your hands because the foam will begin to melt on contact with warm skin. Remove the clear cap. Align the black mark with the nozzle of the actuator. Hold the can upright and press firmly to dispense. Dispense amount that will cover the affected area(s) directly into the cap or onto a cool surface. The can may be placed under cold running water if the can seems warm or the foam seems runny. A small amount of topical foam should be picked up with your fingertips and massaged gently into the affected areas until the foam disappears. Unused medicine that was removed from the can should be throw away. Since this medicine contains alcohol, it will sting or burn. In addition, it has an unpleasant taste if it gets on the mouth or lips. Therefore, do not get this medicine in the eyes, nose, or mouth, or on other mucous membranes. Spread the medicine away from these areas when applying. If this medicine does get in the eyes, wash them out immediately, but carefully, with large amounts of cool tap water. If your eyes still burn or are painful, check with your doctor. It is important that you do not use this medicine more often than your doctor ordered. It may cause your skin to become too dry or irritated.

For patients using the topical solution form of clindamycin:

After washing or shaving, it is best to wait 30 minutes before applying this medicine. The alcohol in it may irritate freshly washed or shaved skin. This medicine contains alcohol and is flammable. Do not use near heat, near open flame, or while smoking. To apply this medicine: This medicine comes in a bottle with an applicator tip, which may be used to apply the medicine directly to the skin. Use the applicator with a dabbing motion instead of a rolling motion (not like a roll-on deodorant, for example). Tilt the bottle and press the tip firmly against your skin. If needed, you can make the medicine flow faster from the applicator tip by slightly increasing the pressure against the skin. If the medicine flows too fast, use less pressure. If the applicator tip becomes dry, turn the bottle upside down and press the tip several times to moisten it. Since this medicine contains alcohol, it will sting or burn. In addition, it has an unpleasant taste if it gets on the mouth or lips. Therefore, do not get this medicine in the eyes, nose, or mouth, or on other mucous membranes. Spread the medicine away from these areas when applying. If this medicine does get in the eyes, wash them out immediately, but carefully, with large amounts of cool tap water. If your eyes still burn or are painful, check with your doctor. It is important that you do not use this medicine more often than your doctor ordered. It may cause your skin to become too dry or irritated.

For patients using the topical suspension form of clindamycin:

Shake well before applying.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For topical dosage form (foam): For acne: Adults and children 12 years of age and over—Apply once a day to areas affected by acne. Infants and children up to 12 years of age—Use and dose must be determined by your doctor. For topical dosage forms (gel, solution, and suspension): For acne: Adults and children 12 years of age and over—Apply two times a day to areas affected by acne. Infants and children up to 12 years of age—Use and dose must be determined by your doctor.

Overdose

If you overdose Generic Cleocin and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Cleocin HCl dosage information

Side effects

The most common side effects associated with Cleocin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Studies on this medicine have been done only in adult patients, and there is no specific information comparing use of vaginal clindamycin in children with use in other age groups.

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Inulin clearance (plasma or urine) is currently considered to be the gold standard for measuring GFR, but in clinical practice the measurement of other exogenous filtration markers from the plasma often replaces that of inulin clearance. Of the 15-20 nucleoid-associated polypeptides, several demonstrated DNA binding activity. IL-4 and IL-10 showed similar concentration-dependent inhibition of MCP-1- and CRP-induced TF expression. These results provide evidence that CBF is functionally important in transactivating the grp78 C1 transcriptional activity, and suggest a possible mechanism by which grp78 transcription is stimulated by calcium depletion. Concentration-effect and dose-response relationships for induction of CYP1A1 and CYP1A2 were similar following in vitro and in vivo exposure to TCDD, although the magnitude of induction was greater for in vivo exposure. The anatomic sites radiographed included the ankle, foot, toe, wrist, hand, finger, and thumb.

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The mechanisms that underlie the symbiotic relationship between Wolbachia and its nematode hosts remain elusive. Over the past few decades, there has been an increasing interest in the measurement of hospital efficiency in developing countries and in Iran. The PRVEPs evoked by different field stimulations can be used to evaluate the functions of the different area retina and can be used to identify the exaggerated or pretended visual dysfunction. Mainstream smoke was generated under ISO 3308 and Canadian Intense (CI) smoking protocols with linear smoking machines with a gas sampling bag collection followed by solid phase microextraction/gas chromatography/mass spectrometry (SPME/GC/MS) analysis. Fever during pregnancy, especially in the period of embryogenesis, is also suspected as being a risk factor for fetal death in human beings.

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The purposes of this article are to (1) offer a background of the current state of the field of pediatric obesity medicine, (2) provide a brief review of the literature summarizing pediatric obesity pharmacotherapy clinical trials, and (3) highlight and discuss some of the unique aspects that should be considered when designing and conducting high-quality clinical trials evaluating the safety and efficacy of obesity medications in children and adolescents. These model organisms were chosen because of their importance and wide use, which made them systems of choice for genome-wide studies. Human herpesvirus 6 infection in febrile infants ninety days of age and younger. Metabolic engineering of Yarrowia lipolytica to produce chemicals and fuels from xylose. Five osteocalcin assays compared: tracer specificity, fragment interference, and calibration. A total of 276 consecutive patients with a first-time severe ankle inversion injury were classified into a ligament injury group (group I) or an avulsion fracture group (group II) on the basis of physical examination and radiographs. TA per se does not impair assisted reproductive treatment outcomes in women without SCH. Strain-specific differences in the impact of human TRIM5alpha, different TRIM5alpha alleles, and the inhibition of capsid-cyclophilin A interactions on the infectivity of HIV-1. Echocardiography-Defined Pulmonary Hypertension in Multiple Myeloma: Risk Factors and Impact on Outcomes.

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Residence in a distressed county in Appalachia as a risk factor for diabetes, Behavioral Risk Factor Surveillance System, 2006-2007. When endothelial cells are pretreated with an inhibitor of superoxide dismutase, diethyldithiocarbamate, the levels of superoxide detected are the same for neutrophils stimulated on plastic and those on the endothelial monolayer, suggesting that endothelial superoxide dismutase may remove a portion of the neutrophil-generated superoxide from the detection system. In anthropology, objective parameters to adequately describe storage conditions and the preservation of mummies have yet to be identified. Our aim was to comprehensively review randomized controlled trials (RCTs) of complementary and alternative therapies for AD. After injection, there was a statistically significant decrease in OCT thickness within 2 h with a plateau phase out to 24 h, followed by a significant drop between 24 and 48 h, and a return towards baseline between 1 week and 1 month. To investigate whether fasciitis is histopathologically demonstrable in patients with dermatomyositis (DM), and to analyze the process of inflammatory progression in myopathy accompanying DM. We reviewed our single institutional experience with pre-surgical Onyx embolization of extra-axial tumors to evaluate its efficacy and safety and highlight nuances of individualized cases. Additionally, we discuss our research results in the field of aseptic loosening.

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This database currently represents the most accurate and comprehensive picture of the newborn abandonment phenomenon in the UK, a phenomenon that is rare but with high media and social interest. Scoring was based on the concept of a visual analogue pain score chart. It provides a number of tools including a 2D glycan drawing and querying interface called DrawRINGS, a Glycan Pathway Predictor (GPP) tool for dynamically computing the N-glycan biosynthesis pathway from a given glycan structure, and data mining tools Glycan Miner Tool and Profile PSTMM. To avoid the discomfort this can cause the patient, we have devised a method that uses feldene flas 20 mg para que sirve standard x-ray equipment but keeps the patient resting supine on the table. Our results support involvement of ODC in primary rather than secondary metabolism in fungi. It is a powerful research tool for examining brain behavior relationships. Actual pulse sequences are given and some experimental results on human volunteers obtained with a 2.0-T KAIS NMR system are also presented. These preliminary results suggest a positive correlation between larger volumes of fluid injected in the epidural space and greater relief of radicular leg pain and/or low back pain. Our results indicate that, as a function of its dose, the wild-type p53 can either protect from death or promote apoptosis.

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Some states have recently passed legislation to address this issue and it is zithromax antibiotic classification expected to be an area of intense legislative debate during this year. To clarify whether free radical, which may play a role in pigment gallstone formation, is present in pigment gallstones in vivo. Screening of a mouse spermatogenic cells lambda gt11 cDNA library with affinity-purified polyclonal antibodies to the tyrosine kinase SP42 allowed the isolation of several positive clones. First, large surveys have confirmed the remarkable efficacy profile of sumatriptan in clinical practice. Even self-motivated patients frequently fail to achieve the treatment goals like developing a normal eating behavior, gaining weight, and changing the underlying dysfunctional behavioral patterns and cognitions. Special skiing programs are available throughout the United States for people of all ages with various disabilities. Therapeutic decisions in otorhinolaryngology are based on clinical experience, surgical skills and scientific evidence. In this study, 339 patients undergoing fundoplication (278 Nissen and 61 Toupet) were evaluated for preoperative G/B symptoms using a 0 to 10 severity visual analogue scale. Is interrupted inferior vena cava a risk factor in cases of bilateral bidirectional Glenn?. The individual components of MetS are differentially associated with HRV in men and in women.

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The results of laboratory investigations, densitometry and thoracic lumbar X-rays were analyzed. The ability to quantify somatic mutations in vivo provides a new source of toxicological information that is relevant to the assessment of cancer risk. Brucella is a zoonotic Gram-negative pathogen that causes abortion and infertility in ruminants and humans. The VAQ total and subscale scores, particularly the peripheral vision subscale, correlated weakly and significantly with visual acuity and visual field scores, especially those from the better eye. Experiments and simulations were conducted to determine if the first harmonic in patients could reasonably be attributed to direction selective mechanisms.

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Breast cancer screening and family history among rural women in Wisconsin. A simple enzyme histochemical method for the simultaneous demonstration of acetylcholinesterase and monoamine oxidase in fixed-frozen sections. However, so far these approaches have not explicitly addressed the challenge of identifying networks representing the interaction of different cell types in a complex tissue. Results on several degraded databases, namely, the CASIA-BIOSECURE and Iris Challenge Evaluation 2005 databases, show the improvement of our can you still buy zantac otc method compared to two available reference systems, Masek and Open Source for Iris (OSRIS), in verification mode. The crushed oyster shell was mainly composed of CaCO(3) with calcite and CaO crystal phase. One of these MAPs, purified from the subpellicular microtubules by a tubulin affinity column, is termed p15alpha. The mean Hachinskis score was less sensitive for differentiating vascular dementia from degenerative dementia. Thus, preventing the accumulation of the inflammatory debris underneath the retina could be expected to alleviate much of the vision loss from this devastating disease.

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Long-term effects of a home-visiting intervention for depressed mothers and their infants. Benign RE occurring during the first year after transplantation and resulting in no loss of graft function do not exert a detrimental influence on long-term kidney graft outcome. The authors report a case of intracerebral Schwannoma discovered in a 13 year old girl who had shown symptoms of increased intracranial pressure since four years and half evolving progressively to aggravation. While the optimal management of early breast cancer patients with sentinel lymph node (SLN) involvement mapped in the internal thoracic chain is still debated, biopsy may be performed when surgeons select patients who are most likely to benefit. We have previously shown that an accumulation of heat shock protein 70 (Hsp70) in a chondrocytic cell line occurred without an activation of the gene itself. A preoperative diagnosis is obviously needed in order to perform the correct treatment. NuMA is dephosphorylated during this assembly process, and the assembly of these NuMA-containing structures is catalyzed by protein dephosphorylation because protein kinase inhibitors enhance their formation and protein phosphatase inhibitors block their formation. Glaucoma was determined based on expert grading of fundus photographs.

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The aim of this paper is to summarize the published data on vitamin D and calcium intake as well as on the prevalence of vitamin D deficiency in the Vietnamese population, and to provide recommendations for a proper strategy to control calcium and vitamin D deficiency in this population. A neuropsychological and behavioural profile of attention deficits in fragile X syndrome. Effects of feeding diets contaminated with Fusarium mycotoxins on blood biochemical parameters of broiler chickens. Lymphadenectomy at second look operation in patients with negative lymph node at primary surgery is unnecessary. Therefore, an effective screening test would have substantial clinical benefits. We investigated whether microRNA signatures in whole blood samples are associated with acute cellular rejection (ACR) after liver transplantation. In the liver of zinc-deficient pregnant rats fatty acid synthetase and delta 9-desaturase activities decreased and diet supplementation with gamma-linolenic acid potentiated this effect will bactrim cause positive drug test .

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There was a trend to increased bleeding with increasing FFR-rFVIIa dose. Body composition and constitution: a constitutional syndrome (1st of 2 parts). Although their long-term effects on the mortality of angina pectoris have not been fully investigated, investigations indicate that, compared with other drugs, beta-adrenergic blocking agents significantly decrease the frequency and duration of angina pectoris. The purpose of this study was to evaluate the bone mineral density (BMD) of 50 patients aged 9-28 years, with thalassemia major and to assess the alterations of bone density in a 4-year follow-up study. The mutation-induced subtle disturbance in the local hydrogen-bond network is accompanied by conformational rearrangements of the protein side chains and bound water molecules. A series of seven children in Hawaii experienced transient cortical blindness following mild head trauma. The enrichment of the activity during the purification of brush border vesicles was measured. The beneficial effects of exercise transcend the simple improved skeletal muscle functionality: systemic responses to exercise have been observed in distal organs like heart, kidney, brain and liver.

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An integrative study with a toxigenic strain of Microcystis aeruginosa exposed to nickel stress. We quantified cerebrovascular reactivity (CVR) using the BOLD response to cyclic changes in PetCO(2) in five healthy volunteers at 1.5 and 3.0 T using spiral imaging and SENSE-EPI. The results were analyzed following the ICCAS workflow-scheme and with standardized questionnaires. See-through multi-projection three-dimensional display using transparent anisotropic diffuser. There are hundreds of implant systems on the market, but the majority lack clinical documentation. Characterization and stability analysis of zinc oxide nanoencapsulated conjugated linoleic acid. Cost effectiveness of type 2 diabetes screening: A systematic review. Lung cancer is the leading cause of cancer mortality in the United States and worldwide. A wealth of biochemical studies suggests that the assembly of these Fe/S clusters on Nar1 cannot be studied in Escherichia coli, as the recombinant protein does not contain the native Fe/S clusters.

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