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Cetdex (Cetirizine)

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Cetdex is in a class of medications called antihistamines. It works by blocking the action of histamine, a substance in the body that causes allergic symptoms. Cetdex is also used to treat itching and redness caused by hives.

Other names for this medication:
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Also known as: Cetirizine


Cetdex (cetirizine) is an antihistamine that reduces the effects of natural chemical histamine in the body. Histamine can produce symptoms of sneezing, itching, watery eyes, and runny nose.

Cetdex is used in adults and children to treat cold or allergy symptoms such as sneezing, itching, watery eyes, or runny nose.

Cetdex is also used to treat itching and swelling caused by chronic urticaria (hives).


This section provides information on the proper use of a number of products that contain cough and cold combinations. It may not be specific to Cetdex-D. Please read with care.

To help loosen mucus or phlegm in the lungs, drink a glass of water after each dose of this medicine, unless otherwise directed by your doctor.

Take this medicine only as directed. Do not take more of it and do not take it more often than recommended on the label, unless otherwise directed by your doctor. To do so may increase the chance of side effects.

Do not give any over-the-counter (OTC) cough and cold medicine to a baby or child under 4 years of age. Using these medicines in very young children might cause serious or possibly life-threatening side effects .

For patients taking the extended-release capsule or tablet form of this medicine:

Swallow the capsule or tablet whole. Do not crush, break, or chew before swallowing. If the capsule is too large to swallow, you may mix the contents of the capsule with applesauce, jelly, honey, or syrup and swallow without chewing.

For patients taking the extended-release oral solution or oral suspension form of this medicine:

Do not dilute with fluids or mix with other drugs.

For patients taking a combination medicine containing an antihistamine and/or aspirin or other salicylate:

Take with food or a glass of water or milk to lessen stomach irritation, if necessary.

If a combination medicine containing aspirin has a strong vinegar-like odor, do not use it. This odor means the medicine is breaking down. If you have any questions about this, check with your pharmacist.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include extreme drowsiness, vision problems, agitation, feeling restless and then drowsy or tired, fast heartbeats, stomach pain, nausea, vomiting, trouble walking, or trouble swallowing or speaking.


Keep out of the reach of children.

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Do not keep outdated medicine or medicine no longer needed.

Keep the liquid form of this medicine from freezing. Do not refrigerate the syrup.

Side effects

The most common side effects associated with Cetdex are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use this medicine if you are allergic to cetirizine or pseudoephedrine, or if you have:

narrow-angle glaucoma; severe high blood pressure (hypertension); severe coronary artery disease; if you are unable to urinate; or if you are allergic to hydroxyzine (Atarax, Vistaril).

Do not use Cetdex-D if you have taken an MAO inhibitor in the past 14 days. A dangerous drug interaction could occur. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.

Ask a doctor or pharmacist if it is safe for you to take this medicine if you have other medical conditions, especially:

heart disease, coronary artery disease, high blood pressure, or heart rhythm disorder; diabetes; a thyroid disorder; glaucoma; kidney or liver disease; an enlarged prostate; or problems with urination.

FDA pregnancy category C. It is not known whether Cetdex-D will harm an unborn baby. Do not use this medicine without a doctor's advice if you are pregnant.

Cetirizine and pseudoephedrine may pass into breast milk and may harm a nursing baby. Antihistamines and decongestants may also slow breast milk production. Do not use this medicine without a doctor's advice if you are breast-feeding a baby.

Older adults may be more likely to have side effects from Cetdex-D.

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