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Biocitral (Calcitriol)

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Biocitral is a hydroxycalciol that is calcidiol in which the pro-S hydrogen of calcidiol is replaced by a hydroxy group. It is the active form of vitamin D3, produced fom calciol via hydoxylation in the liver to form calcidiol, which is subsequently oxidised in the kidney to give Biocitral.

Other names for this medication:
Actical, Admax, Alfacal, Alfacalcirol, Arachitol, Calasto, Calcibest, Calcigra, Calcikind, Calcimet, Calcirol, Calcor, Caldix, Calgel, Calotec, Calsure, Caltin, Caltive, Calzem, Cholical, Coecoral, Devita, Dmcal, Koncal, Minroset, Nutribone, Osteobel, Ostonex, Ostriol, Politrol, Primacal, Rical, Riecal, Ritoca, Rockbon, Roical, Rolsical, Solbiocal, Vezocal, Vitalpha

Similar Products:
Anafranil, Zyvox, Myambutol, Dilantin, Provigil, Arava, Kemadrin, Zomitac, Macabi, Vasopin, Glybid, Azyter, Balzam, Lizocas,

Also known as: Calcitriol


Generic Biocitral is a synthetic vitamin D analog which is active in the regulation of the absorption of calcium from the gastrointestinal tract and its utilization in the body. The two known sites of action of Generic Biocitral are intestine and bone. Generic Biocitral receptor-binding protein appears to exist in the mucosa of human intestine. Additional evidence suggests that Generic Biocitral may also act on the kidney and the parathyroid glands. Generic Biocitral is the most active known form of vitamin D3 in stimulating intestinal calcium transport. In acutely uremic rats Generic Biocitral has been shown to stimulate intestinal calcium absorption. The kidneys of uremic patients cannot adequately synthesize Generic Biocitral, the active hormone formed from precursor vitamin D. Resultant hypocalcemia and secondary hyperparathyroidism are a major cause of the metabolic bone disease of renal failure. However, other bone-toxic substances which accumulate in uremia (eg, aluminum) may also contribute. The beneficial effect of Generic Biocitral in renal osteodystrophy appears to result from correction of hypocalcemia and secondary hyperparathyroidism. It is uncertain whether Generic Biocitral produces other independent beneficial effects. Biocitral is also known as Calcitriol. Generic Biocitral treatment is not associated with an accelerated rate of renal function deterioration. No radiographic evidence of extraskeletal calcification has been found in predialysis patients following treatment. The duration of pharmacologic activity of a single dose of calcitriol is about 3 to 5 days. Generic name of Generic Biocitral is Calcitriol. Brand name of Generic Biocitral is Biocitral.


Generic Biocitral is available in capsules (0.25 mcg) and liquid form. Capsules must be swallowed whole. Do not crush or chew them. If you are prescribed the liquid form, use as directed. Follow dosing instructions closely. Do not take this medication with mineral oil or magnesium containing antacids which may reduce its effects. Foods rich in vitamin D include: fortified dairy products, eggs, sardines, cod liver oil, chicken livers and fresh-water fish. Vitamin D is also obtained from periodic exposure to the sun. It is important to maintain a well-balanced diet while taking this medication. Calcium supplements may be recommended in addition to this medication. If you want to achieve most effective results do not stop taking Generic Biocitral suddenly.


If you overdose Generic Biocitral and you don't feel good you should visit your doctor or health care provider immediately.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Biocitral are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Problems in older adults have not been reported with intake of normal daily recommended amounts. Studies have shown that older adults may have lower blood levels of vitamin D than younger adults, especially those who have little exposure to sunlight. Your health care professional may recommend that you take a vitamin supplement that contains vitamin D.


To determine the suitability of irradiated homograft cartilage in pediatric laryngotracheal reconstruction (LTR). However, misconceptions regarding transmission and gender bias related to sexual behaviour and contracting the disease prevailed. Together, these results suggest that H2 may have an effect on rice stress tolerance by modulating the output of hormone signaling pathways. Last, new microscopy methods that allow single-cell optical imaging of radionuclides are reviewed. The current explosive growth of publicly available protein structures is producing large volumes of data for computational modelling and drug design methods. Sensitivity and positive predictive value of cardiac auscultation compared with echocardiography is poor, regardless of the expertise of the auscultator. Fundoscopy revealed bullous retinal detachment with dark hazy vitreous.

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There was a marked increase in Borrelia-specific antibody titre. However, the osteocalcin gene, which is expressed during the final stage of osteoblast differentiation when extracellular matrix mineralization occurs, is not upregulated. Colorectal distension and immunohistochemical staining of sensory neurons were used to evaluate NGF and ASICs contribution to the development of butyrate-induced CHS. Acquired arachnoid cysts are rare and usually arise after trauma, infection, or haemorrhage. The patients developed right ventricular failure, which persisted after surgery and rendered weaning from cardiopulmonary bypass unsuccessful. Differences in the performances among the four groups were not statistically significant on either the first or the second day alone or when the data of the two days were combined. Identifying biomarkers that would be easily measured and followed in patients with acute exacerbation of COPD seems to be highly attractive.

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The areas with high stress concentration increased with increasing tear size. Significant curvature appeared during the 6-month history of pain in association with an L5-S1 spondylolisthesis. Seventy-two healthy New Zealand rabbits were used for the procedure and were randomly divided into two groups: SCI group and SHAM group, which was both divided into 6 subgroups, such as the vehicle group, the MPss intrathecal injection groups (1.5 mg/kg, 3.0 mg/kg, 6.0 mg/kg group), the MPss intravenous injection group and the combined injection group. Thermography and laser-Doppler flowmetry for monitoring changes in finger skin blood flow upon cigarette smoking. Image analysis by pulse coupled neural networks (PCNN)--a novel approach in granule size characterization. Here, we used single-nucleotide polymorphism genotyping and data on numerous environmental variables to describe the genetic basis of local adaptation in 21 populations of teosinte, the wild ancestor of maize. We have previously reported that paramyosin admixed with BCG can induce partial protection against Schistosoma mansoni in mice. Users demand intuitive, quick and platform-agnostic access to data, software tools, and infrastructure from millions of hardware devices. Interestingly, overexpression of constitutively active FOXO1 also led to activation of MEK and Akt phosphorylation.

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Nine valve tissue cultures were positive despite previous antibiotic treatment. Response was defined as cessation or significant improvement of fistula drainage. The DOX-loaded, DNA-wrapped HNTs (HDD) show sustained DOX release over two weeks without initial burst of DOX indicating delayed DOX release inside cells. We provide evidence that expression of the innate immune receptor Toll-like receptor 4 (TLR4) and the extracellular matrix glycosaminoglycan hyaluronan (HA) on AEC2s are important for AEC2 renewal, repair of lung injury and limiting the extent of fibrosis. AS was assessed by PWV and, after the measurement of PWV, the presence of AS was determined. Determination of the difference in percentages of ectopic pregnancies in patients with and without tubal pathology after in-vitro fertilisation and consequences for prevention. Study of the first psychotic episode and its prodromic phases in Mexico. Studies have confirmed that the elimination of lamotrigine and the active metabolite of oxcarbazepine is enhanced during pregnancy. Delay in recovery of arterial pressure after DFT with propofol and delay in arousal and discharge of patients with thiopental are major disadvantages of the regimens. The activation of TRPA1 in DRG neurons by noxious GD may be involved in acute visceral pain.

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The clinical presentation of the condition and recommendations for treatment by early recognition and aggressive, early surgical intervention together with high doses of penicillin are discussed. The microencapsulation improved the oxidative stability of the oil and this procedure was satisfactorily applied in powdered food. Our work opens new possibilities for the customizing of laser modes at source. A considerable body of literature has developed since the late 1950s which defines an important role for this technique in clinical practice. Omission of PD in appropriate cases was associated with reduced fluoroscopy time and total contrast used without affecting procedural success. Laparoscopic revision of a gastrojejunostomy, even after an open revision following an open gastric bypass, can be done safely.

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Serum FT(4) should be targeted at the high-normal range in GH-deficient patients only off GH replacement. The patient underwent total tumor extirpation with the surrounding hepatic parenchyma. 26 patients on immunotherapy and 21 controls with symptomatic treatment only finished the study. Biological Origin of Native Sulfur in Salt Domes of Texas and Louisiana. By considering the GTPase and kinase signalling and trafficking of two such closely-related receptors, we begin to understand how cell migration is coordinated. The NADH-ubiquinone-1 reductase activities of NDH-1 are inhibited by rotenone, capsaicin, and dicyclohexylcarbodiimide. Comparative chemical studies of the polyherdral proteins of the nuclear polyhedrosis viruses of Bombyx mori and Galleria mellonella. Blockage of the Shh signaling pathway with a pharmacological inhibitor, cyclopamine, abolished the CEPO-induced neurogenesis.

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However, aromatase expression in combination with high PR expression may select letrozole treated patients with longer TTP. They are also present along the sutures of the endothelial cells of venules. Polysomnography was performed over two consecutive nights and the first-night effect and group differences were evaluated. Amphetamine primes motivation to gamble and gambling-related semantic networks in problem gamblers. The quantitative indicator--the potential risk factor of a specific text-book for the visual system of pupils--has been substantiated. Residents of long-term care facilities--a distinct subpopulation of elderly people--are at particularly high risk for developing pneumonia. This study provides valuable information for research on galectin-3.

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Removal of arsenic from synthetic acid mine drainage by electrochemical pH adjustment and coprecipitation with iron hydroxide. Despite the potential demand, inhibitors specifically targeting insulin have been few in number. Therefore, we examined whether candesartan cilexetil is effective in reducing urinary protein excretion or in controlling hypertension in patients with renal allograft dysfunction. Coral recovery in the central Maldives archipelago since the last major mass-bleaching, in 1998. Although high abundant cystatin c (CysC) in cerebrospinal fluid (CSF) is well known, its ambiguous role associated with pain still remains unclear. Mouse neuroblastoma cells, which can be induced to undergo reversible differentiation in culture, have been used as a model to investigate the effects of ultra-violet (U.V.) radiation on terminally-differentiated nerve cells. Meta-analyses of hippocampal size have indicated that this structure is smaller in schizophrenia. High-speed confocal fluorescence imaging with a novel line scanning microscope. Visible light-mediated oxidative decarboxylation of arylacetic acids into benzyl radicals: addition to electron-deficient alkenes by using photoredox catalysts.

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The risk of GDM is greater for pregnant women from selected ethnic groups (such as Indigenous, Asian and Indian) and for older pregnant women. In-depth studies of senior schoolchildren conducted in 1989-2005 revealed long-standing unfavourable trends in their health status including marked deterioration of functional activities and physical development, increased prevalence of chronic diseases, and changes in the overall morbidity structure. The analysis based mainly on T-invariants of the model properties has been made and some biological conclusions have been drawn. Integrodifference equations in patchy landscapes : II: population level consequences. The problems associated with diagnosis and treatment of Borrelia burgdorferi infection are pointed out. A questionnaire form and the Intensive Care Experience Scale were used as data collection tools. Successful reproduction depends critically on social interactions.

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Proliferating cell nuclear antigen (PCNA) expression as a prognostic indicator for renal cell carcinoma: comparison with tumour grade, mitotic index, and silver-staining nucleolar organizer region numbers. The chimpanzee remains the most physiological model to study the innate and adaptive immune responses, but its use is ethically difficult and is now very restricted and regulated. Cocaine addicted men have low startle magnitude persisting during prolonged abstinence. Genetic dissection of human systemic lupus erythematosus (SLE) has been under intense studies during the past decade. Islet cell transplantation for insulin-dependant diabetes mellitus: perspectives from the present and prospects for the future. 5-LO- and dual LO-deficient mice exhibited an attenuated response to zymosan-induced peritoneal inflammation, emphasizing roles for 5-LO in regulating vascular permeability. This study represents part of an ongoing effort to develop an appropriate seizure model for investigations of anticonvulsant action in the developing rat.

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To assess the trends in blood pressure (BP) affecting lifestyle factors in hypertensive and normotensive Finns from 1982 to 2002. This review is focused on the summary of published knowledges on the antioxidant and potential chemopreventive effects of biologically active substances present in the extracts of four plants of the family Lamiaceae (sage, thyme, rosemary and lavander) in different animal and in vitro systems. One infant treated with CPAP via an endotracheal tube and given pure oxygen for a long time had gross abnormalities suggesting bronchopulmonary dysplasia. The findings provide further support for a critical role of serotonin in declarative episodic memory. Tramadol has been reported to be analgesic in clinical neuropathic pain, with varying levels of efficacy due to a patient population that has had neuropathic pain for a wide range of time. We have now extended this work by measuring concentrations of L-glutamate and L-aspartate in the putamen from 45 human autopsy specimens. This can also be valuable as a local flap, especially for adjacent groin wounds that are not uncommon after vascular interventions. This article seeks to identify the role of state health agencies (SHAs) in building capacity for conducting HIAs and the key components of initiatives that produced effective HIAs and HIA programs.

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Our data support a model for a VP1-dependent positive feedback mechanism regulating Vp1 expression during seed maturation. Onyalai is diagnosed by finding the combination of haemorrhagic blisters in the mouth and severe thrombocytopenia, and by excluding other possible causes of thrombocytopenia. Macronuclear Subunits of Tetrahymena thermophila Are Functionally Haploid. Relative to traditional fee-for-service Medicare, managed care plans caring for Medicare beneficiaries may be better positioned to promote recommended services and discourage burdensome procedures with little clinical value at the end of life. Interestingly, weight changes did not vary with age in this interval. The suggestions included avoiding loud talking, careful handling of the incubator doors and keeping mobile phones on silent mode. Low power gas discharge plasma mediated inactivation and removal of biofilms formed on biomaterials. The results showed thioridazine 10mg tablets on the one hand the dependence of the incapacity to work on the involvement of the knees and their exposure to stress during work. However, other alternatives, especially factors that could implicate a hypoxic encephalopathy as the origin of the dementia, cannot be entirely ruled out. Use of complex surgical procedures, patterns of tumor spread, and CA-125 predicts a risk of incomplete cytoreduction: a Korean Gynecologic Oncology Group study (KGOG-3022).

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Three operators, working randomized, used the same computerized pachymeter (DGH 1000) to make the measurements. It was reduced in size by a lithotripter, as used for stone disintegration in urology, and then removed. More vigilant fluid management is imperative in neonates, particularly those in the open environment. A comprehensive clinical examination of 462 patients (391 men and 71 women) with alcohol addiction has been conducted albenza generic to identify gender-related characteristics of alcohol addiction in the elderly (over 60 years old) in relation to the time of their first doctor visit. In this study, we investigated the mechanisms underlying the IL-15 regulation in the initial CD62L-dependent contact between PB CD16(-) NK cells and HUtMVECs.

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Two population-based follow-up surveys were conducted to evaluate the quality of maternal care in 25 Local Health Units (LHUs) in Italy during 2008-2011. Human motrin dosage baby biodistribution and dosimetry of the SPECT benzodiazepine receptor radioligand iodine-123-iomazenil. In contrast, little genetic divergence was found between coastal and west-Andean individuals, suggesting recent interruption of gene flow between these localities. Integration of the reflex pharyngeal swallow into rhythmic oral activity in a neurologically intact pig model. The freely available X-ray crystal structure (PDB ID: 1JIE) was used as the template to model the protein followed by loop generation and development of troponin complex for both the troponin I wild type and four mutants (NCBI ID: PRJNA194382). we examine the evidence on four devices that measure cardiac output using minimally invasive and noninvasive techniques.

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Audiometry showed conductive deafness in two cases and sensorineural deafness in one case. We examined patient beliefs about provider awareness of medication use, patient-reported prevalence and nature of provider counseling about medications, and the impact of health literacy on these outcomes. In general, KDTW sediment samples contained slightly higher amounts of PCDD/DFs (average: 1100, range: 120-2400) than the LE sediments (average: 920, range: 580-1300) on a pg/g dry wt (dw) basis. Bladder cancer, including urothelial carcinoma (UC), is the most common malignancy of the urinary tract and the fourth most frequent cancer overall in men. Prognostic significance of serum CA 125 antigen assay in patients with non-small cell lung cancer. Furthermore, we find that second-order electron-hole recombination of photo-excited charges is retarded at lower temperature.

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Morphologicaly progressive focal segmental to global glomerulosclerosis is present, accompanied clinically by increasing proteinuria and deteriorating renal function. Here we describe that all the polymorphisms clustered in the intracellular loop connecting repeats I and II (I-II loop) increase the surface expression of extracellularly tagged Ca(v)3.2 channels. Studies have been directed at investigating the specific functional role of this novel subset as an APC accessible to blood-borne antigen, as well as the conditions under which hematopoiesis is initiated in spleen, and the type of progenitor involved. Functional differences have been proposed for these clathrins despite high sequence similarity. The patient had a complete recovery after adequate medical treatment. We report the case of a 50-year-old man, treated for syphilitic arthritis evolving for 4 years, who presented with a table of rheumatoid arthritis. Eligible patients were randomized either to intra-operative iv administration of fluid boluses based on stroke volume measured by oesophageal Doppler (probe arm) or to iv fluid based on clinical indicators (no-probe arm). In the previous research, we found that D609 (tricyclodecan-9-yl-xanthogenate) could induce human marrow stromal cell (hMSC) differentiation to neuron-like cells. It is unclear whether there is a difference in risk between elite and non-elite participants with will effexor show on a drug test further prospective studies needed to evaluate this. By electron microscopy, Golgi membranes in BIG1-depleted cells were less sharply defined than those in mock or BIG2 siRNA-treated cells, with more vesicle-like structures at the transface.

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Incubation of selected fermentable fibres with feline faecal inoculum: correlations between in vitro fermentation characteristics and end products. Mercury allergy in a contact dermatitis clinic in Northern Ireland. Comparison between ischaemic and anisomycin-induced preconditioning: role of p38 MAPK. Further characterization of these proteins could provide greater insight into the mechanisms involved in regulation of neurogenesis in the adult central nervous system (CNS) and potentially identify points of therapeutic intervention. For example, the protonation state of the glutamate residue within the active site cannot be clearly determined from the crystal structure. In order to confirm the epithelium and mesenchyme interactions during the early development of the mouse tongue, a recombination assay was conducted after the recombination assay at E12.5 and E13.5 for 2 days using an in vitro organ culture.

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Many patients experience severe hopelessness and suicidal ideation and the disorder is associated with one of the highest mortality rates of all psychiatric disorders. Neurogenesis in the embryonic and adult brain occurs under the control of intrinsic and extrinsic factors. Beta-blockers had no material impact on the HRQOL of patients with peripheral arterial disease who also had COPD. Although it is often difficult for the cytological study to differentiate low-grade lymphoma from reactive lymphoid proliferation, FNA results in combination with clinical and radiological studies (triple testing) generally what allergy medicine can you mix with zyrtec provide guidance for appropriate investigations, and helps avoiding unnecessary major operation. Multilocus approaches for the measurement of selection on correlated genetic loci.

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Countries aiming to implement a mammography/QA program may select/prioritise the tests depending on available technology and resources. It is noteworthy that blood requirements in anephric patients are two to three times greater than those of nonanephric hemodialyzed patients. New technique of intracorneal ring segments suturing after migration. In a single-dose study, ascending doses of 2, 5 and 10 mg were administered to cohorts of eight young subjects. Transient transfection assays using COS-7 cells and mouse metallothionein-I (MT-I) or rat NAD(P)H:oxidoreductase 1-based reporter genes demonstrate that copper activates transcription via metal and antioxidant response elements. This novel mechanism identifies potential new treatment strategies and biomarkers to improve and individualize antihypertensive therapy in the elderly. Existing theory predicts that male signalling can be an unreliable indicator of paternal care, but assumes that males with high levels of mating success can have high current reproductive success, without providing any parental care.

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Where issues of concern were identified, these related mainly to communication and areas were identified where change could take place in the future. A quantitative RT-PCR assay for rapid detection of Eurasian-lineage H10 subtype influenza A virus. Facilitative glucose transport is mediated by members of the Glut protein family that belong to a much larger superfamily of 12 transmembrane segment transporters. Transient expression and RNA interference silencing of ZmMAP65-1a in mesophyll protoplasts further revealed that ZmMAP65-1a is required for the BR-induced increase in expression and activity of superoxide dismutase (SOD) and ascorbate peroxidase (APX). The production of reactive oxygen species in intact isolated nerve terminals is independent of the mitochondrial membrane potential. Targeting of biotinylated compounds to its target tissue using a low-density lipoprotein receptor-avidin fusion protein. Dietary trans-rich and interesterified fats were compared to an unmodified saturated fat for their relative impact on blood lipids and plasma glucose. Each biomaterial presented thin-layer zones not present before enzymatic action.

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