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Atipam (Lorazepam)
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Atipam

Atipam, an antianxiety agent, has the chemical formula, 7-chloro-5-(o-chlorophenyl)-1,3- dihydro-3-hydroxy-2H-1,4-benzodiazepin-2-one. It is a nearly white powder almost insoluble in water. Each Atipam tablet, to be taken orally, contains 0.5 mg, 1 mg, or 2 mg of Atipam. The inactive ingredients present are lactose monohydrate, magnesium stearate, microcrystalline cellulose, and polacrilin potassium.

Other names for this medication:
Almazine, Anxilor, Anxionil, Anxipose, Atipam, Biokalm, Biolar, Calmese, Dulozep, Larosh, Larpose, Lopam, Lopez, Loracalm, Lorakar, Loralite, Lorazam, Lorazepam, Lorazine, Loricon, Loripam, Lorivan, Lorpam, Lorvin, Lotweet, Nexlor, Norpose, Olraz, Trapex, Urpam, Zelor, Zepatrac, Zepnap

Similar Products:
Imovane, Arcoxia, Cialis, Adalat, Clozaril, Allegra, Trambax, Haledol, Sildenafilum, Betanif, Recotens,

Also known as: Lorazepam

Description

Atipam tablets should be taken in the way your doctor prescribed them. Don’t take more or less Atipam than prescribed without first talking with your doctor.

Timing

Atipam is usually taken two or three times daily. These doses are usually spread out at equal intervals. However, when Atipam is used for insomnia, it’s usually taken just once at bedtime.

Taking Atipam with food

You can take Atipam with or without food. If it upsets your stomach, try taking it with food to help decrease this side effect.

Can Atipam be crushed?

Yes, Atipam can be crushed. Some Atipam tablets may also be split. If you’d like to split your tablets, ask your pharmacist if it’s safe to do so.

Dosage

When given intramuscularly, Atipam Injection, undiluted, should be injected deep in the muscle mass.

Injectable Atipam can be used with atropine sulfate, narcotic analgesics, other parenterally used analgesics, commonly used anesthetics, and muscle relaxants.

Immediately prior to intravenous use, Atipam Injection must be diluted with an equal volume of compatible solution. Contents should be mixed thoroughly by gently inverting the container repeatedly until a homogenous solution results. Do not shake vigorously, as this will result in air entrapment. When properly diluted, the drug may be injected directly into a vein or into the tubing of an existing intravenous infusion. The rate of injection should not exceed 2.0 mg per minute.

Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit. Do not use if solution is discolored or contains a precipitate.

Atipam Injection is compatible for dilution purposes with the following solutions: Sterile Water for Injection, USP; Sodium Chloride Injection, USP; 5% Dextrose Injection, USP.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of lorazepam can be fatal if you take it with alcohol, opioid medicine, or other drugs that cause drowsiness or slow your breathing.

Overdose symptoms may include extreme drowsiness, confusion, slurred speech, feeling restless, muscle weakness, loss of balance or coordination, feeling light-headed, slow heartbeats, weak or shallow breathing, or coma.

Storage

Store Ativan at room temperature away from moisture, heat, and light.

Keep track of the amount of medicine used from each new bottle. Atipam is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

Side effects

The most common side effects associated with Atipam are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Atipam should be avoided in people with:

Allergy or hypersensitivity – Past hypersensitivity or allergy to Atipam, to any benzodiazepine, or to any of the ingredients in Atipam tablets or injections

Severe respiratory failure – Benzodiazepines, including Atipam, may depress central nervous system respiratory drive and are contraindicated in severe respiratory failure. An example would be the inappropriate use to relieve anxiety associated with acute severe asthma. The anxiolytic effects may also be detrimental to a patient's willingness and ability to fight for breath. However, if mechanical ventilation becomes necessary, Atipam may be used to facilitate deep sedation.

Acute intoxication – Atipam may interact synergistically with the effects of alcohol, narcotics, or other psychoactive substances. It should, therefore, not be administered to a drunk or intoxicated person.

Ataxia – This is a neurological clinical sign, consisting of unsteady and clumsy motion of the limbs and torso, due to failure of gross muscle movement coordination, most evident on standing and walking. It is the classic way in which acute alcohol intoxication may affect a person. Benzodiazepines should not be administered to already-ataxic patients.

Acute narrow-angle glaucoma – Atipam has pupil-dilating effects, which may further interfere with the drainage of aqueous humor from the anterior chamber of the eye, thus worsening narrow-angle glaucoma.

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The results of the study demonstrated the need for addressing modifiable risk factors such as smoking, metabolic syndrome, and undernutrition in older adults. Basal levels of serum LH and the serum LH response to GnRH were not affected by B administration. Preparing teachers of CAM therapies in conventional healthcare settings. Genes homologous to heat shock protein 70 have been described in parasitic protozoa. The treatment results of concurrent radiochemotherapy at the University of Rostock were analyzed retrospectively.

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In this article, observations and speculations of some prominent workers in the field of neuroscience are described with focus on their conclusions, rather than specific findings as they pertain to the mind-body relationship. Evaluation of antidotes: activities of the International Programme on Chemical Safety. Diclofenac and other non-steroidal anti-inflammatory drugs (NSAIDs) interfere with cyclo-oxygenase-mediated synthesis of prostaglandins, resulting in the inhibition of inflammatory immune responses. The significance of a secondary spectrum and a tertiary spectrum in lens design is also reviewed. Under physiological loads, debonded cemented femoral stems have been shown to move within their cement mantle and generate a fluid pump that may facilitate peri-prosthetic osteolysis by pressurizing fluid and circulating wear debris. It caused a retention of M1 protein in the cell nucleus and a decrease of its expression on the plasma membrane. Interestingly, all agonists that reinstated responding in the present study caused expression of locomotor sensitization and vice versa.

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Relationship among guanine nucleotide exchange, GTP hydrolysis, and transforming potential of mutated ras proteins. Unprecedented coupling of allenylidene and diynyl metal complexes: a bimetallic ruthenium system with a C7 conjugated bridge. This study demonstrated a social gradient in the presence of fissure sealants, but no such gradient in dental caries levels. Empiric therapy with systemic anticoagulation may be indicated in patients with stroke unexplained by carotid atherosclerotic disease. In the first phase, after osteotomy of the proximal fibula was performed, two Ilizarov rings were attached to the proximal tibia and one Ilizarov ring was applied to the distal tibia.

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Pre- and postjunctional modulation by endothelin-1 of the adrenergic neurogenic response in canine mesenteric arteries. Significant pathological changes can be present in the placenta of patients with PIH complicated by IUGR, and may be intimately related to abnormal expressions of VCAM-1 in the placenta. However protocols for optimum culture of hESC-RPE are not well established. In the stenotic side the glomerular filtration rate which acutely decreased following captopril, tended to return toward pretreatment levels on prolonged captopril administration (up to 2 years), while the value remained unchanged in the nonstenotic side of the kidney. The rods of nocturnal retinas have a unique inverted pattern, where heterochromatin localizes in the nuclear center, whereas euchromatin, as well as nascent transcripts and splicing machinery, line the nuclear border. It has been established that inherited mutations in p53, BRCA1, and BRCA2 significantly contribute to breast cancer risk, although the importance of an inherited ATM mutation is controversial. SIRPabodies selectively bound to dual antigen-expressing tumor cells in the presence of a large antigen sink.

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Analysis of the various A-scan criteria (internal structure, reflectivity, borders, consistency and sound attenuation) provided a pathognomonic combination of these criteria for each lesion, enabling further histological diagnosis. Social marketing: a strategy for promoting the health-related professions. Histological investigations of the tumor revealed a polypoid angiofibromatous lesion of the renal pelvis which was benign in nature. Metallothionein: a potential marker for differentiating benign and neoplastic gastrointestinal lymphoid infiltrates. Analyses of variance confirmed significantly higher scores in the female adolescents in cognitions of rejection of violence, prosocial cognitions, cooperative conflict solving, positive strategies for coping with violence, and positive social behaviors. There has been an unexplained decrease in the incidence of transfusion-transmitted malaria in recent years. Conservative treatment approach allowing continued activity and strengthening exercises resulted in full functional recovery over the next 6-8 months.

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Histone H3 N-terminal peptide binds directly to its own mRNA: a possible mode of feedback inhibition to control translation. No side effects were reported by the subjects receiving tyrosine. A Wilcoxon signed-rank test demonstrated that the Eye Movement Desensitization and Reprocessing group experienced a significant reduction in pain intensity after treatment intervention, whereas the control group did not. TPCL and lobulated tumor contour as well as WHO histologic classification and M-K stage were independent predictors of pleural recurrence after thymoma resection. Thus, research has recently increased, exploring a wide range of disease control strategies (e.g., genetic, chemical, physical). Simple high-performance liquid chromatographic method for the determination of acyclovir in human plasma using fluorescence detection. Because ubiquitinated proteins accumulated after MG115 treatment, it was confirmed that ubiquitin-dependent protein degradation, and thus proteasomal activity were blocked. The sensitivity and specificity of the assay were 97.4 per cent and 97.6 per cent, respectively, using a cut-off point based on 35 per cent binding of a reference positive control serum. In the foliation plane, a significant clustering of the a-axis is observed and tentatively attributed to intracrystalline deformation mechanisms.

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Multiple wavelength, differential absorption lidar (DIAL) measurements reduce the effects of differential target reflectance and molecular absorption interference. The relationship between exercise induced bronchial obstruction and health related quality of life in female and male adolescents from a general population. In vivo labeling also revealed a circadian rhythm of mRNA synthesis for the CABII gene family as a whole. Intensive effort has been directed in recent years to unveil the molecular, cellular and immune mechanisms, as well as the virus-host interactions associated with latent HSV infection. Simultaneous and proportional force estimation for multifunction myoelectric prostheses using mirrored bilateral training.

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The degree of dysphonia was related to the size of the glottal gap and bowing. These results indicate that they could be exactly classified as cathepsin E. To facilitate and organize cross-border testing, common practices need to be created at the level of the EU, and follow-up studies are needed to monitor their effects. Nitric oxide and cyclic GMP levels in sickle cell patients receiving hydroxyurea. Endocrine disorders associated with diabetes mellitus are described. Collectively, these data suggest that Mcb1 is not the sole factor involved in ubiquitin recognition by the 26S proteasome and that Mcb1 may interact with only a subset of ubiquitinated substrates. Correlates of adherence to supervised exercise in patients awaiting surgical removal of malignant lung lesions: results of a pilot study. The formulas of the footprint of the dispersed spectra are derived, and the numerical simulation is given. Anastomotic complications in minimally invasive coronary bypass grafting. This low resolution can be considered a design trade-off cost of a bright image.

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A review of etiology, research design, and methods of risk reduction. In some of the genomes we investigated, however, it also forms distinct, sharp clusters in chromosome-specific positions, and the brightest fluorescence was always observed on group 4 chromosomes. The polypeptide behaves as monomer in solution and is N-glycosylated. The approach may provide advanced slice-based measures of function during the LV remodeling process and aid in the development of therapies. These observations provide molecular evidence that endocytosis can be regulated by the immune environment. A combination of behavior modification and medication resulted in a large decrease in intensity and frequency of OCD in most animals.

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Here, we show that inositol polyphosphates can modulate the activities of several chromatin-remodeling complexes in vitro. The association of CHIP expression and clinical parameters was analyzed using the Chi-square test. In this paper, the electrochemical behaviors of rutin at the MWNTs-IL-Gel/glassy carbon electrode (GCE) were investigated. This paper focuses on Chinese parent-child relationships with respect to this value system from the perspective of young adult Chinese immigrants in the United States. Substituted (aryloxy)alkanoic acids as antagonists of slow-reacting substance of anaphylaxis. Segregation studies and linkage analysis of Atlantic salmon microsatellites using haploid genetics. Two cases of therapy-related acute promyelocytic leukemia (t-APL) after mantle cell lymphoma and gestational trophoblastic disease. Thrombospondin 1 (TSP1), a multifunctional, matricellular glycoprotein, is expressed de novo in many inflammatory disease processes, including glomerular disease. Irradiation of cell nuclei with charged particles leads to the spatially defined production of DNA damage along the particle trajectories, thus facilitating studies on the dynamics of radiation-induced protein foci associated with lesion processing.

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Importantly, we demonstrate that these phenotypes are rescued by exogenous CDK18 in a kinase-dependent manner. The ideal endoscopic treatment method has not yet been established but will likely vary depending on the site and specific nature of the injury and any concomitant biliary ductal pathology. Intra-arterial chemoembolization with albumin microspheres including mitomycin C in inoperable hepatic cancer. A new genus of tribe Erythroneurini from Thailand, Thaioneura gen. capsici-binding peptides from a random peptide library that showed high binding affinity and specificity toward P. Immunoinflammatory mechanisms are implicated in the atherogenic process. Histopathological examination revealed that the pituitary tumor was a prolactinoma with diffuse amyloid deposition and that the second tumor was a typical meningioma. These methods, have an outstanding reduction in dental weakening and in times of the endodontic treatment performance. NADPH Oxidase System as a Superoxide-generating Cyanide-Resistant Pathway in the Respiratory Chain of Corynebacterium glutamicum. Our approach is to use structural mimics of the two phosphorylated forms can you drink alcohol while on sporanox of HPr, where histidine 15 is replaced by a negatively charged glutamate and serine 46 is changed to an aspartate, both alone and in combination.

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The face of prostate cancer has been dramatically changed since the late 1980s when PSA was introduced as a clinical screening tool. Identification of maize histone deacetylase HD2 as an acidic nucleolar phosphoprotein. Knowledge of human papillomavirus (HPV) and the HPV vaccine in a national sample of Australian men and women. Some high-threshold MUAPs deteriorated similarly to low-threshold MUAPs. This amidaldehyde was further metabolized by two routes, one by reduction of the amidaldehyde into the corresponding alcohol followed by mono-demethylation and subsequent aromatic O-sulphation, the second by oxidation of the amidaldehyde into the oxamic acid followed by mono-demethylation and subsequent aromatic O-sulphation. Current calls for conservation through captive breeding require that efficient and reliable antifungal treatments be developed for target species. Beyond the known disease genes DES, FLNC, MYOT, CRYAB, ZASP, BAG3, FHL1 and colitis ciprofloxacin flagyl dosing TTN, mutations in PLEC, ACTA1, HSPB8 and DNAJB6 have also been associated with a MFM phenotype. Miniaturized linear time-of-flight mass spectrometer with pulsed extraction.

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The expression of srp 60 may reflect a protective mechanism of the epithelial cells against injury triggered by immunorelated agents. beta-cell hyperactivity was present earlier in first-gestation non-diabetic fasted NOD and NOD/SCID mice than in age-matched C57BL/6 mice, assessed by increased insulin/glucose ratio after GTT. In this article, we review some twin studies, and discuss the dynamic interactions between stochastic, environmental, and epigenetic variables that influence neurobiological phenotypes. The aim of this study was to investigate with ultrasound the acute effects of extreme physical exercise on knee and ankle joints and their surrounding structures in trained athletes. beta-Bungarotoxin (BuTx)-binding cells were immunocytochemically examined in zithromax 500 mg tri pack the developing rat cerebellum.

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Inhibition can you take zyrtec and cough medicine together of human telomerase by PNA-cationic peptide conjugates. The occurrence of anemia in small cell lung cancer patients during first-line chemotherapy. In this review, we focus on microRNA biogenesis, regulation, detection, and quantification with an emphasis on cellular localization and how these concepts may be linked to disease processes such as osteoarthritis. The presence of the MUC5AC and MUC2 mucins was investigated with antisera raised against synthetic peptides with sequences from the respective apoproteins. Employment patterns were tracked by examining a longitudinal database of all 201,463 nurses registered with the College of Nurses Ontario (Canada) between 1993 and 2004. The melanoma-associated transmembrane glycoprotein Gpnmb controls trafficking of cellular debris for degradation and is essential for tissue repair. This is the result of social and economic activities of human beings or from their normal physiological functions. A group of 6 clinically stable HD patients without any type of IDN served as the control group. Using a recombinant adeno-associated viral vector expressing murine interleukin-6 (rAAV-IL-6), we examined the chronic effects of centrally expressed IL-6 on food intake, body weight and adiposity in male Sprague-Dawley rats, and investigated the underlying mechanisms. albidus was the most competitive strain to grow in the buckwheat doughs, accordingly, the levan produced by this strain was further examined for its molecular mass and size determination.

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