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Astrim (Trimethoprim)

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Astrim (generic name: Co-trimoxazole; brand names include: Septra / Ciplin / Septrin) is a combination of two antibiotics (trimethoprim and sulfamethoxazole) used to treat a wide variety of bacterial infections.

Other names for this medication:
Alfatrim, Bacta, Bactiver, Cotribene, Dientrin, Diseptyl, Ditrim, Doctrim, Dotrim, Eliprim, Gentrim, Ikaprim, Medibiot, Megaset, Neotrim, Novidrine, Plocanmad, Primazol, Primazole, Sinatrim, Sulbron, Sulotrim, Trelibec, Trimaxazole, Trimethazol, Trimexazol, Trimezol, Trimosazol, Tripur, Trisulf, Tritenk, Urobactrim, Vanasulf

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Also known as: Trimethoprim


Astrim contains a combination of sulfamethoxazole and trimethoprim. Sulfamethoxazole and trimethoprim are are both antibiotics that treat different types of infection caused by bacteria.

Astrim is used to treat ear infections, urinary tract infections, bronchitis, traveler's diarrhea, shigellosis, and Pneumocystis jiroveci pneumonia.


Take Astrim exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets.

Drink plenty of fluids to prevent kidney stones while you are using this medicine.

Sulfamethoxazole and trimethoprim doses are based on weight in children. Use only the recommended dose when giving this medicine to a child.

Use this medicine for the full prescribed length of time, even if your symptoms quickly improve. Skipping doses can increase your risk of infection that is resistant to medication. This medicine will not treat a viral infection such as the flu or a common cold.

You may need frequent medical tests.

This medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using Astrim.

Store at room temperature away from moisture, heat, and light.

Detailed Astrim dosage information


If overdose is suspected, contact a poison control center or emergency room immediately. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: severe nausea/vomiting/diarrhea, severe dizziness or drowsiness, mental/mood changes.


Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.

Side effects

The most common side effects associated with Astrim are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Generic Astrim if you are allergic to Generic Astrim components. Do not take Generic Astrim if you're pregnant or you plan to have a baby, or you are a nursing mother. Generic Astrim can harm your baby. Do not take Generic Astrim if you have anemia. Generic Astrim can't be given to children younger than 2 months old. Avoid exposure to sunlight, sunlamps, or tanning beds while taking Generic Astrim. Be careful with Generic Astrim if you have kidney or liver disease, folic acid deficiency, asthma or severe allergies, AIDS, glucose-6-phosphate dehydrogenase deficiency (G6PD deficiency); if you are malnourished. Be careful with Generic Astrim if you take seizure medication such as phenytoin (Dilantin); diuretic (water pill); blood thinner such as warfarin (Coumadin); methotrexate (Trexall, Rheumatrex); methotrexate (Trexall, Rheumatrex); or an ACE inhibitor such as benazepril (Lotensin), captopril (Capoten), fosinopril (Monopril), enalapril (Vasotec), lisinopril (Prinivil, Zestril), moexipril (Univasc), perindopril (Aceon), quinapril (Accupril), ramipril (Altace) or trandolapril (Mavik). It can be dangerous to stop Generic Astrim taking suddenly.

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The labile iron-mediated oxidative damage caused by UVA to mitochondria leads to necrotic cell death via adenosine triphosphate depletion. Hoffman failure criterion was considered for prediction of cement-bone interface debonding. These isolated cartilage injuries, if not repaired surgically with restoration of articular congruency, may have a high rate of progression to posttraumatic osteoarthritis, resulting in significant morbidity and loss of function in the young, active patient. We examined sleep in male rats, either hypocretin neuron-ablated orexin/ataxin-3 transgenic (narcoleptic) rats or their wild-type littermates. In the event of a small skin graft failure, the preserved skin graft was separated from its donor site and used as a new skin graft during wound dressing. Red meat, diseases, and healthy alternatives: A critical review.

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Anonymous oocyte donation and participation in organ and blood/tissue donation programmes were studied specifically among Irish fertility patients. Northern analysis showed cellular expression of messenger RNA (mRNA) for PAI-1, uPA, and uPA receptor. Using drugs to treat children with attention deficit hyperactivity disorder (ADHD) may have reached a plateau, after a steep rise in prescriptions over the past 18 years. Effect of redo status on midterm survival was assessed using a Cox proportional hazards model. Cells were also screened microscopically for morphological signs of intoxication. The search for the infectious agents responsible for cat-scratch disease, bacillary angiomatosis, and related syndromes has a long and often circuitous history. This paper presents guidelines that represent a synthesis of evidence-based approaches and the expert consensus of this panel and are intended to aid physicians new to caring for patients with EB when operative management is indicated. Dynamic cardiac PET is used to quantify molecular processes in vivo.

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Previously, it was shown that a highly metastatic melanoma cell line B16F10 bound to galacto-side-functionalized nanoparticles much stronger than the corresponding less metastatic B16F1 cells. Induction of NF-kappaB and the iNOS promoter by GHSA exhibited dose-dependent kinetics at concentrations ranging from 3 to 1000 microgram/ml. However, evolutionary forces acting on DUXY genes may have induced amino acid sequence differences in the orthologous chimpanzee and human DUXY open reading frames (ORFs). A potential involvement of some of the reported MER repeats in the regulation of transcription and genetic rearrangements is suggested. A prospective randomized controlled trial of sclerotherapy vs ligation in the prophylactic treatment of high-risk esophageal varices. A total of 44 pregnant women with different degrees of hydronephrosis and 46 without hydronephrosis were consecutively enrolled in this prospective study. The data were validated by comparing them with figures generated by practice-based searches, measuring the uptake of recording of consultations over time, and comparing records of consultations in the case notes with those on the practice computers.

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Surgical treatment of acute acromioclavicular joint injuries using a modified Weaver-Dunn procedure and clavicular hook plate. Methylene blue and fatal encephalopathy from ackee fruit poisoning. Educational effects of a single distribution of a leaflet on alcohol and pregnancy among female university students. Design, synthesis and evaluation of (18)F-labeled bradykinin B1 receptor-targeting small molecules for PET imaging. Zygotes and early embryos were covered with a few polyhedral CC cells possessing scarce and short microvilli and a large amount of pleomorphic blebs.

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The cytomorphology in combination with the clinical history and immunohistochemical findings can indicate a definitive diagnosis and avoid additional time-consuming diagnostic procedures for appropriate clinical management. In addition, ETS levels encountered by these more highly exposed workers are lower that those estimated by the Occupational Safety and Health Administration. We showed previously that the peroxisome proliferators di(2-ethylhexyl)phthalate (DEHP), clofibrate, and 4-chloro-6-(2,3 xylidino)-2-pyrimidinylthio (N-beta-hydroxyl)acetamide (BR931) alter hepatic sex steroid metabolism and receptor expression during induction of hepatic hyperplasia and hepatocellular carcinoma (HCC) in rats. In 3 of 4 xenografts, immunoreactivity for human-specific monoclonal antibody (MAb) for alpha1,2(IV) was seen in the BM-like structures. A novel potassium sensing in aqueous media with a synthetic oligonucleotide derivative. Surprisingly, simultaneous transplantation of wild-type bone marrow cells rescued the production of p50/p65-deficient lymphocytes.

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The aim of the present study was to evaluate the histological/biomechanical effects of Transforming growth factor-beta1 (TGF-beta1) and vascular endothelial growth factor 165 (VEGF(165)) gene transfer on Achilles tendon healing in rabbits. Chemotherapy, endocrine therapy, HER2-directed agents and bisphosphonates in the adjuvant setting are discussed. Macitentan, a tissue-targeting endothelin receptor antagonist for the potential oral treatment of pulmonary arterial hypertension and idiopathic pulmonary fibrosis. The aim of this study was to investigate the effect in vitro of antisense oligodeoxynucleotide (ASODN) of PCNA on its gene expression and cell proliferation in human esophageal squamous cell cancer T. A case of duodenal duplication is reported, and related articles published from 1999 to 2009 on PubMed were reviewed. Previous investigations demonstrated that two-spotted spider mite (TSM) inhalation causes allergic asthma in agricultural workers. If confirmed, a very high Lp(a) lipoprotein level could be one risk factor for pre-eclampsia that is genetically determined.

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Investigations were conducted to assess the ecological factors governing distribution and survival of keratinophilic fungi in poultry farm soils. Analysis of the anatomic relations of the humeral head and the glenoid cavity is particularly important for clinical study of shoulder arthroplasty and glenohumeral instability. Although the patient received partial, substandard therapy for TCRBCL, an excellent prolonged complete response ensued, thus, giving further credence to the fact that malignant lymphomas symmetrel brand name and TCRBCL in particular, are a protean group of disorders which should be precisely and accurately classified before the proper therapeutic strategies can be outlined. We propose a model for relaxation-stimulated transcription in which promoter clearance is the rate-limiting step. Histology may provide a link between clinical response to antirejection therapy and graft function. The near-infrared fluorescent dye LS-288 has distinct lifetimes when bound to protein versus free in solution, providing contrast between the protein-rich viscera and the mostly protein-free bladder. Contractile properties of left ventricular myocytes isolated from spontaneously hypertensive rats: effect of angiotensin II.

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Evaluation of the effect of interleukin-6 and human extracellullar matrix on embryonic development. This paper discusses the Value project, which assessed the value to clinical decision-making of information supplied by National Health Service (NHS) library and information services. Oligonucleotide microarray analysis of gene expression in follicle-stimulating hormone-treated rat Sertoli cells. Acetyl- and butyrylcholinesterase (AChE, BuChE) activities were studied in rabbits with experimentally induced daunorubicin cardiomyopathy. In this paper, we illustrate the data processing methods and data challenges faced by our team during a study of surgical scheduling practices at the Vancouver Island Health Authority. Distraction has been shown to help to reduce procedural distress in children. The survival of IgD patients is shorter than that of other MM patients. Subjects were imaged using high-resolution peripheral quantitative computed tomography at the distal radius and tibia.

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Separating line broadening due to spin exchange and dipolar interactions. Blood pressure and the T174M and M235T polymorphisms of the angiotensinogen gene. Return of ovarian function is possible after prolonged periods in women with chemotherapy-induced ovarian failure. Screening for gestational diabetes: a systematic review and economic evaluation. Over the 5 years, the diabetics show a continual change in the shape of their brightness matching function. Mean cost was significantly less for the clean group than for the sterile group. The effects of outpatient civil commitment on community tenure and functioning were studied in a group of 20 patients with a history of recurrent hospitalizations, noncompliance with outpatient treatment, and good response to treatment. The aim of this study was to analyse the effect of purified mast cell tryptase on non-sensitized human isolated bronchi. Such nucleotide divergence may not only lead to changes in protein function and antigenicity, but may also norvasc high blood pressure medication alter gene regulation programs as exemplified by the finding that the LdI-9-5 and LdE-6-1 genes were expressed only in visceralizing leishmanias.

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International trends in coronary heart disease mortality and incidence rates. Hair 3TC concentrations were detected through the LC-MS/MS system. Stimulation of higher motor centres revealed monosynaptic excitatory postsynaptic potentials (EPSPs) from cortico-, rubro-, tecto-, reticulo-, interstitio-, fastigio- and trigeminospinal fibres. For prevalence of hypertension, five of 10 studies reported higher rates in South Asian men than in white men. Single-crystalline wurtzite structure of InN QDs was confirmed by X-ray diffraction. We also evaluated whether multiple integrin subunits have a role in RET-mediated cell migration. Hispanics are the most recent immigrants to the New Orleans area. Familial polyposis coli has generally been considered a disorder of adulthood that is rarely identified in children. Comparison between palladium alloys and non-precious metal alloys.

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