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Asart (Losartan)
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Asart

Asart is a medication mainly used to treat high blood pressure. It is also used for diabetic kidney disease, heart failure, and left ventricular enlargement. It is taken by mouth. It may be used alone or in addition to other blood pressure medication.

Other names for this medication:
Angilock, Fensartan, Lacine, Lavestra, Loplac, Lopress, Losacar, Losapot, Losaprex, Losarb, Losardil, Losartic, Losatrix, Losazide, Lostad, Lostan, Lostat, Nefrotal, Osartan, Prelow, Repace, Sanipresin, Sarlo, Sartaxal, Tacardia, Temisartan, Tiasar, Zaart

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Also known as: Losartan

Description

Asart (losartan) belongs to a group of drugs called angiotensin II receptor antagonists (sometimes called ARB blockers). It keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow.

Asart is used to treat high blood pressure (hypertension) in adults and children who are at least 6 years old. It is also used to lower the risk of stroke in certain people with heart disease.

Asart is also used to slow long-term kidney damage in people with type 2 diabetes who also have high blood pressure.

Dosage

Usual Adult Dose for Diabetic Nephropathy:

Initial dose: 50 mg orally once a day Maximum dose: 100 mg orally once a day Comments: -If hypertensive patients with left ventricular hypertrophy or type 2 diabetic nephropathy patients require titration from initial dose, increase to 100 mg orally once a day. -Antihypertension is substantially present within 1 week but in some studies the maximal effect occurred in 3 to 6 weeks. Uses: -Treatment of hypertension. -To reduce the risk of stroke in patients with hypertension and left ventricular hypertrophy. -Treatment of diabetic nephropathy with an elevated serum creatinine and proteinuria (urinary albumin to creatinine ratio 300 mg/g or greater) in patients with type 2 diabetes and a history of hypertension.

Usual Adult Dose for Hypertension:

Initial dose: 50 mg orally once a day Maximum dose: 100 mg orally once a day Comments: -If hypertensive patients with left ventricular hypertrophy or type 2 diabetic nephropathy patients require titration from initial dose, increase to 100 mg orally once a day. -Antihypertension is substantially present within 1 week but in some studies the maximal effect occurred in 3 to 6 weeks. Uses: -Treatment of hypertension. -To reduce the risk of stroke in patients with hypertension and left ventricular hypertrophy. -Treatment of diabetic nephropathy with an elevated serum creatinine and proteinuria (urinary albumin to creatinine ratio 300 mg/g or greater) in patients with type 2 diabetes and a history of hypertension.

Usual Pediatric Dose for Hypertension:

6 Years or Older: Initial dose: 0.7 mg/kg orally once a day (up to 50 mg total) Comments: -May be given as a tablet or suspension. -Doses above 1.4 mg/kg (or 100 mg) daily have not been studied in pediatric patients.

Detailed Asart dosage information

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Storage

Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Asart are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Changes in renal function including acute renal failure can be caused by drugs that inhibit the reninangiotensin system and by diuretics. Patients whose renal function may depend in part on the activity of the renin-angiotensin system (e.g., patients with renal artery stenosis, chronic kidney disease, severe congestive heart failure, or volume depletion) may be at particular risk of developing acute renal failure on COZAAR. Monitor renal function periodically in these patients. Consider withholding or discontinuing therapy in patients who develop a clinically significant decrease in renal function on Asart.

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In addition, adenoidectomy was performed for eight of these children and a biopsy of adenoid tissue was taken as well. These studies underscore the potential of non-invasive brain mapping techniques to characterize the genetic influence on the human corticospinal motor system. Although some recent guidelines recommend an early invasive strategy for non-ST-segment elevation acute coronary syndrome (NSTEACS), several studies have failed to identify any benefit for very early intervention for NSTEACS. At 56 days post-KA, Timm staining disappeared completely, whereas VGluT-1-, Synapsin-1-, and ZnT3-IR were increased in the sprouted MF boutons. Epstein-Barr virus infection and oncogenesis in primary immunodeficiency. Furthermore, we show that caveolin-1 can function as a negative regulator of VEGF-R (KDR) signal transduction in vivo. High-level vancomycin resistance has now been reported in a single clinical isolate of S. We also compared practices based in Europe in 60 respondents and in the United States in 70. The Authors emphasize the importance of the Doppler-sonography for the diagnosis of the outlet thoracic syndrome with our personal casuistry. The EQ-5D-3 L showed better discrimination than EORTC-8D with higher effect sizes.

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Solution properties and vesicle formation of rhamnolipid biosurfactants produced by Pseudomonas aeruginosa SP4. We present analysis and design of microring resonators integrated with reflective elements to obtain custom wavelength-selective devices. Differential sialylation of cell surface glycoconjugates in a human B lymphoma cell line regulates susceptibility for CD95 (APO-1/Fas)-mediated apoptosis and for infection by a lymphotropic virus. There is growing literature on which to base recommendations, particularly regarding washout periods. All but one of the children then received treatment with desmopressin in standard dosage, and the response was documented. Both TMT-A and TMT-B were associated with weaker grip strength, and the TMT-A and MIS with poorer mental health. The characteristics of this sample exemplify the complex nature of adolescent substance use and abuse among adolescents entering outpatient treatment programs. The presence of two structural elements was found to be required for high inducer potency: (i) hydroxyl groups at ortho-position on the aromatic rings and (ii) the beta-diketone functionality. This technique required repeated corneal debridement to achieve complete resolution in these three cases. We have found that expression of the short form of integral membrane protein 2B (ITM2B(S)) in IL-2-stimulated T cells, as well as in COS-7 cells, induces apoptosis.

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Substance misuse in a high security hospital: period prevalence and an evaluation of screening. (b) Due to the easy set up procedure, less prone to error in the use of well chamber and with the use of a new lead insert, we conclude in our case that, the well system can be used for monthly calibration of HDR source and timer linearity measurements. After one week of transfection, mesenchymal-epithelial transition was induced in MSCs. Everolimus or CsA allowed the boosting of T-cell-dependent and -independent secondary humoral responses. In Group PD (pseudodiscrimination) the presentation of each compound was followed by the outcome in half of the trials. 1,2-dicyanobenzene and analytically pure soluble nickle salt were used as the nickle phthalocyanine (NiPc) reactants and chemical synthesis technique was used to prepare NiPc doped sol-gel materials at several temperatures. Spinal tumors in 37 dogs: clinical outcome and long-term survival (1987-1994).

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This adaptive mechanism ensures rapid detection and resolution of conflict in potentially threatening situations signaled by emotional stimuli. Therefore, working setbacks experienced by senior nurses must be investigated. Molecular genetic differentiation of ethnic populations in Southern and Eastern Siberia based on mitochondrial DNA polymorphism. A significant reduction in the innervation of the smooth muscle cells is observed. MYEOV: a candidate gene for DNA amplification events occurring centromeric to CCND1 in breast cancer. Ethodin has been used to induce labor through a mechanism that does not involve the estrogen-preparatory process being postulated as necessary for ensuring the events in a normal labor.

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Local mechanical characteristics might be related to the atypical presentations. This meta-GWAS of the NMR identifies CYP2A6 variants, replicates the top-ranked single nucleotide polymorphism from a recent Finnish meta-GWAS of the NMR, identifies functional mechanisms, and provides pan-continental population biomarkers for nicotine metabolism. The loss of transfected H-ras sequences occurs with a high frequency in cells supertransfected with the SV40 anti-sense construct. If the recurrence of macular edema was diagnosed during the monthly visit, additional injections were given as needed. Prolactin exerts hematopoietic growth-promoting effects in vivo and partially counteracts myelosuppression by azidothymidine. To explant or not to explant: an invasive and noninvasive monitoring protocol to determine the need of continued ventricular assist device support. Can psychotropic medications change ethnoculturally determined behavior?.

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Spinal Infections Among Patients With Long-Term Central Venous Catheters for Home Parenteral Nutrition. This study sets out to find out how much postural variation occurs during the driving task and how sensitive is the human body to these changes. The temperature variation of the elastic constants is qualitatively similar to the typical experimental data for bent-core nematics. Carcinoma arising in a choledochal cyst retained after enteric drainage is discussed in comparison with primary carcinoma. The goal of the present study was to analyze the reliability of the identification of the precentral knob in the axial image of magnetic resonance imaging or functional MRI (fMRI) for the detection of M1. Restoration of elbow flexion in brachial plexus avulsion injury: comparing spinal accessory nerve transfer with intercostal nerve transfer. Medical treatment with intravenous amphotericin B followed by oral itraconazole (400 mg per day) improved both clinical and radiological status.

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In 2 of the patients a decrease in the number of immature bone marrow cells positive for the myeloid antibody anti-My7 was observed. Microarray analysis showed significant progestin (R5020)-regulation of 162 genes in pubertal organoids and 104 genes in adult organoids, with 68 genes regulated at both developmental stages. These data show that although participation of other neurohormones cannot be ruled out, aldosterone blockade (eplerenon) ameliorates myocardial dysfunction persisting after ventricular tachycardia by preventing coronary endothelial dysfunction. Less is known though about how different cognitive functions covary with alcohol use, craving, and post-traumatic stress symptom severity among trauma-exposed individuals with AUD. Autologous T-cell proliferation was stimulated by purified protein derivative (PPD) in IFN-gamma-treated synovial cells and treatment of these synovial cells with IL-10 also suppressed T-cell proliferation. To compare different methods of cytology sampling from biliary strictures and evaluate the use of cytology in this context. Moreover, we found an independent inverse relationship between hemoglobin levels and TX-dependent platelet activation. n., described here, was discovered in 2010, during the third year of the study.

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We have characterized a novel approximately 1.1-MDa protein in S. Prior to the development and implementation of an immunization reminder/recall system intervention, we explored the experiences, preferences and perceptions towards childhood immunization reminder/recall among 614 mothers of infants in Ibadan, Nigeria. Genetic variation in the CRP gene is associated with microangiopathic but not macroangiopathic or cardioembolic stroke in a large German stroke sample. Commentary: Exploring more dermatology education for medical students. Eleven categories, including an open-ended option, were provided for participants to explain their nonreporting behavior. This study examined outcome of AVR after previous CABG and reviewed possible indications for valve replacement at the time of initial myocardial revascularization. Attitudinal moderation of correlation between food liking and consumption. The direct peel-away sheathed needle vessel puncture technique and the modified Seldinger technique used to place PICC lines in children have similar complication rates. Chemical composition of ribs from subjects habituated to a diet low in calcium. Re: Novel method of surgical mask tying to prevent spectacle slippage.

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Sex-specific differences in T cell homing may explain increased disease severity in female mice. Immunocytochemistry was performed to investigate the distribution at this site of the high affinity glutamate transporter GLAST and glutamate metabolizing enzyme glutamine synthetase. At the present time, standard therapy for invasive bladder cancer includes radical cystectomy and urinary diversion. The survival rates for mutants from which water was withheld were low compared with those for wild-type plants. Kinesiophobia and its relation to pain characteristics and cognitive affective variables in older adults with chronic pain. Occupational health training in India: Need for a competency-driven approach. Fabrication and evaluation of chitosan-gelatin based buckling implant for retinal detachment surgery. Sixty studies were chosen for charting the data, 14 studies examined personality traits exclusively, 31 studies examined affective disorders exclusively, and 15 studies investigated both.

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tropicalis resulting in a significant increase in the percentage of transgenic animals that reach adulthood is presented, as well as improvements in tadpole and froglet husbandry, which have facilitated the raising of large numbers of adults. To demonstrate that the free-energy potential as determined by the signaling is the driver of motion, we inhibited two proteins most involved in maintaining the free-energy gradient. Prediction of protein retention times in anion-exchange chromatography systems using support vector regression. (n-3) diets rich in polyunsaturated fatty acids (PUFA) reduce the atherogenic lipoproteins, especially the VLDL (very low density lipoproteins) rich in triglycerides but also the LDL, more effectively than (n-6) PUFA-rich diets. Pain report and the relationship of pain to physical factors in the first 6 months following spinal cord injury. In this study, we analyze 117 hospital systems in six states and report on their convenient care strategies. In Japan the term was adopted as a substitute term for MBD in the 1970s. The advent of computed radiography (CR) and direct radiography (DR) has helped bring x-ray film into the world of computers. It is estimated that between 350 and 400 cases of SUDEP occurred in England and Wales in 1997 in those 16-50 years.

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A pilot study to examine the feasibility and effects of a home-based aerobic program on reducing fatigue in children with acute lymphoblastic leukemia. Their structures were established by spectroscopic and chemical methods. DM patients are distinguished by their cutaneous manifestations. Monocytes and macrophages have receptors for the iron-binding protein lactoferrin. Biliary stones after liver transplantation (LT) rarely occur but a focus on those complications and their treatment is needed. The mechanisms regulating such outcome may be due not only to the anti-inflammatory properties of IL-10 but also, directly or indirectly, to antibacterial features of this molecule.

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Two allergenic components, termed J1 and J2, were isolated from a soluble egg antigen preparation (SEA) of Schistosoma japonicum by anion-exchange chromatography on DE52 and gel chromatography on Sephacryl S-200. The protal blood flow was assessed in 46 patients with hepatocellular carcinoma, 81 with cirrhosis, and 110 control subjects using an ultrasonic B-mode pulsed Doppler duplex system. Exposures to HIV are frequently managed in the emergency department (ED) for assessment and potential initiation of HIV postexposure prophylaxis. Serum thrombopoietin (c-Mpl ligand) levels in patients with liver cirrhosis. To identify scientific evidence of occupational illness of dockworkers published in the literature. The effect of chemical modification on ligand charge distribution is mostly local. ARMS subjects exhibited reduced functional connectivity between the left ventral anterior insula and other SN regions. Effect of converting enzyme inhibition with captopril on baroreflex sensitivity. Based on the literature and clinical judgment, a simple Institutionalisation-Index was formed reflecting the degree of institutional protection in supported housing, long-term day care, partial hospitalisation and full hospitalisation programmes.

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Autologous dermal graft combined with a modified degloving procedure for penile augmentation in young adults: a preliminary study. Indexes including serum lipids, C-reactive protein (CRP), and area ratio of aortic plaque/intima (PIR), and intima-media thickness ratio (IMT) were examined. These findings suggest that the activation of serotonergic neuronal activity in the dorsal hippocampus is linked to mediation of anxiety-related behavior. Serum activity of chitotriosidase, lysozyme and cathepsin H in patients with lung cancer and patients with inflammatory exudate (preliminary report). Coinfusion of CGP 54626A (100 microM), a GABA(B) receptor antagonist, counteracted the effect of baclofen on the forskolin-stimulated cAMP efflux. Data spanning across nearly 20 years suggest that stressors perceived to have contributed to a notable life change increased the likelihood of scoring above the cut off score for common mental disorder in comparison to stressors experienced without subsequent life change. In this paper, it is demonstrated that UCP1 is not expressed in any liver cell type of rat while UCP2, a recently cloned homologue of UCP1, is expressed at a very high level in Kupffer cells but not in hepatocytes. To evaluate the effectiveness of locally applied vancomycin powder at different times postinfection in a contaminated traumatic animal model. Intraoperative implantation radiation therapy plus lumpectomy for carcinoma of the breast.

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As part of the International Study of Asthma and Allergies in Childhood (ISAAC) Phase Three, 13- to 14-year-old children completed written and video questionnaires obtaining data on current symptoms of asthma, rhinoconjunctivitis, and eczema, and a written environmental questionnaire norfloxacin and tinidazole tablet in hindi obtaining data on putative risk factors, including acetaminophen use in the past 12 months. A single subcutaneous administration of albutropin (0.3, 1.5 and 4 mg/kg) increased plasma insulin-like growth factor 1 (IGF-1) levels for up to 7 days. We demonstrate that both corals harbor Endozoicomonas bacteria as their prevalent symbiont. A Bayesian network is better at detection and can detect errors with less information than existing automated models, suggesting that Bayesian model may be an effective means for reducing medical costs and improving patient safety. We show that these responses depend upon the expression levels of microbial recognition receptors TLR2 and TLR4 on the cell surface. Few autopsy cases of sudden death in renal transplant recipients have been reported in the literature. We retrospectively reviewed the records from 441 consecutive heart transplantation procedures done in 416 patients with use of an immunosuppressive protocol that attempted corticosteroid withdrawal within 2 months of transplantation.

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Through interviews and document reviews, we examined the current policies and procedures of the ANG in relation to influenza surveillance, protonix medication sheet outbreak response, vaccination, and use of antiviral drugs. Early clinical trial results show good tolerability and robust immune responses to both components. A lamb-meat-based formula for infants allergic to casein hydrolysate formulas. FDG-PET does not have a primary role for staging regional nodes in patients with clinically localized melanoma. Added value of pretreatment (18)F-FDG PET/CT for staging of advanced gastric cancer: Comparison with contrast-enhanced MDCT. The immediate maximal mean change in supine blood pressure (BP) was similar with both drugs, but occurred earlier with captopril. Comparison of team-focused CPR vs standard CPR in resuscitation from out-of-hospital cardiac arrest: Results from a statewide quality improvement initiative.

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If predictions are interpreted with caution and transferred accurately to the model surgery, they can provide an excellent visual aid during presurgical treatment planning and patient presentation. To our knowledge, these cases are the first published reports of lovastatin-induced rhabdomyolysis associated with azithromycin and clarithromycin. The first scan masked by software correlated with the delayed scan for myocardial regions supplied by the left circumflex (LCx) and right coronary artery (RCA), but not the left anterior descending (LAD). The sustainability study was carried out in the Segura River Basin (SRB) in South-eastern Spain. The effects of morphine, cocaine, amphetamine and hashish on the phagocytosis of the protozoon Tetrahymena pyriformis strain W. Nitrotyrosine formation after activation of murine macrophages with mycobacteria and mycobacterial lipoarabinomannan. Effect of Osthole on Adrenocortical Function in Y1 Mouse Adrenocortical Tumor Cells. Demonstration of maturation dependence in single cells is important in understanding the cellular origins of developmental effects on NMR characteristics in cell assemblies such as brain.

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We investigated the SCF expression histopathologically in normal and SSC skin, and compared the expression with the serum SCF levels measured with a specific enzyme-linked immunosorbent assay. To investigate whether the degree of glomerular structural lesions in young patients with type 1 diabetes and microalbuminuria was associated with urinary albumin excretion rate (AER) 6 years later and whether the AER level was influenced by blood glucose control, blood pressure, or glomerular filtration rate (GFR). Genetic testing is now available for many SMAs, providing important diagnostic and prognostic information. 60 primary care professionals, 30 doctors and 30 nurses, selected at random and placed in 6 discussion groups. Effect of the triterpenoid fraction of Centella asiatica on macromolecules of the connective matrix in human skin fibroblast cultures. Human immunodeficiency virus-associated T-cell lymphoblastic lymphoma in AIDS. The influence of phenergan dose adults sleep gravity on composition uniformity and microstructure in immiscible Al-In alloys. There were 63 reports of angiooedema/urticaria in patients monitored on the IMMP, giving a reported rate of 1.2/1000 (0.9-1.5).

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These cells expressed the CYP11B2 mRNA, a rate-limiting enzyme in the aldosterone biosynthesis. Insulin and insulin-like growth factor (IGF-1) are mitogenic for fibroblasts and smooth muscle cells. Transfer function for image formation of objects reconstructed from volume holograms with different wavelengths. On their way to the synapse and back, neuronal proteins are carried in cargo vesicles along axons and dendrites. The effectiveness of hydroxy-methylglutaryl coenzyme A reductase inhibitors (statins) in the elderly is not influenced by apolipoprotein E genotype. Design and characterizations of two novel cellulases through single-gene shuffling of Cel12A (EG3) gene from Trichoderma reseei. Currently, these tumors are found incidentally in asymptomatic patients by advanced diagnostic modalities. Their pathogenesis is heterogeneous, with contributions from both bone strength and trauma.

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We investigated the variations in hemodynamic parameters and brain natriuretic peptide (BNP) levels before and after permanent pacemaker implantation for complete AV block. Sporadic loss of best corrected vision in the PRK eyes not found in the LASIK eyes and other measures of visual function require further study. Urine and tissue homogenates are serially diluted in PBS and cultured on appropriate agar. Patient selection, counseling, and IOL placement with optimal astigmatism correction are crucial. Variation of glucose tolerance in adult patients with cystic fibrosis: What is the potential contribution of insulin sensitivity?. Patients with RA had significantly higher PAI-1 antigen levels and PAI-1 activity in SF than patients with SpA. Serum dehydroepiandrosterone sulphate (DHEA-S) concentrations were also increased during ACTH therapy above the normal prepubertal range. It is known that the C-terminal fragment of Clostridium perfringens enterotoxin (C-CPE) binds the TJ protein claudin and disrupts the tight junctional barrier without inducing a cytotoxic effect. Films and discs of Sum-Met combinations were successfully prepared with improved release and mucoadhesive properties. Eight subjects with early HIV infection, 9 HIV-seronegative controls, and 10 chronically HIV-infected subjects without neurologic impairment underwent 1H magnetic resonance spectroscopy.

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