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Armodafinil is currently FDA-approved to treat excessive daytime sleepiness associated with obstructive sleep apnea, narcolepsy, and shift work disorder. It is commonly used off-label to treat attention deficit hyperactivity disorder, chronic fatigue syndrome, and major depressive disorder. It has been shown to improve vigilance in air traffic controllers. Armodafinil is approved by the U.S. FDA for the treatment of narcolepsy and shift work sleep disorder, and as an adjuvant therapy for obstructive sleep apnea.For narcolepsy and obstructive sleep apnea, Armodafinil is taken as a once daily 150 mg or 250 mg dose in the morning. For shift work sleep disorder, 150 mg of Armodafinil are taken one hour prior to starting work. Slow dose titration is needed to mitigate some side effects.

Other names for this medication:
Armod, Armodafinil, Biryth, Waklert

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Armodafinil (armodafinil) is a medication that promotes wakefulness.

Armodafinil is used to treat excessive sleepiness caused by sleep apnea, narcolepsy, or shift work sleep disorder.


Take Armodafinil exactly as prescribed by your doctor. Follow all directions on your prescription label. Do not take this medicine in larger or smaller amounts or for longer than recommended. Armodafinil may be habit-forming. Never share Armodafinil with another person, especially someone with a history of drug abuse or addiction. Selling or giving away this medicine is against the law.

Read all patient information, medication guides, and instruction sheets provided to you. Ask your doctor or pharmacist if you have any questions. Armodafinil is usually taken each morning to prevent daytime sleepiness, or 1 hour before the start of a work shift to treat work-time sleep disorders.

You may take this medicine with or without food. Armodafinil is usually given for up to 12 weeks. Follow your doctor's instructions.

If you are taking this medicine to treat sleepiness caused by obstructive sleep apnea, you may also be treated with a continuous positive airway pressure (CPAP) machine. This machine is an air pump connected to mask that gently blows pressurized air into your nose while you sleep. The pump does not breathe for you, but the gentle force of air helps keep your airway open to prevent obstruction. Do not stop using your CPAP machine during sleep unless your doctor tells you to. The combination of treatment with CPAP and Armodafinil may be necessary to best treat your condition.

Taking this medication does not take the place of getting enough sleep. Talk with your doctor if you continue to have excessive sleepiness even while taking this medicine. Armodafinil will not cure obstructive sleep apnea or treat its underlying causes. Follow your doctor's instructions about all your other treatments for this disorder.


When a person takes too much Armodafinil, overdose symptoms may include unusual bruising or bleeding, nausea, diarrhea, and chest pain. Specific effects will be based on certain factors. If the Nuvigil overdose was recent, healthcare providers may give certain medicines, place a tube in the stomach to pump the stomach, or treat the symptoms that occur as a result of the overdose.


Store at room temperature away from moisture and heat. Keep track of the amount of medicine used from each new bottle. Armodafinil is a drug of abuse and you should be aware if anyone is using your medicine improperly or without a prescription.

Side effects

The most common side effects associated with Armodafinil are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not use Armodafinil if you are allergic to armodafinil or modafinil (Provigil).

To make sure Armodafinil is safe for you, tell your doctor if you have ever had:

liver or kidney disease; heart disease or a heart muscle or valve disorder such as mitral valve prolapse; high blood pressure, heart disease, or prior heart attack; mental illness or psychosis; or drug or alcohol addiction.

It is not known whether Armodafinil will harm an unborn baby. Armodafinil has been reported to be associated with growth restriction (small fetus) and miscarriage. Tell your doctor if you are pregnant or plan to become pregnant.

Use a barrier form of birth control (condom or diaphragm with spermicide). Hormonal contraception (birth control pills, injections, implants, skin patches, and vaginal rings) will not effectively prevent pregnancy while you are taking Armodafinil.

It is not known whether Armodafinil passes into breast milk or if it could affect the nursing baby. Tell your doctor if you are breast-feeding.

Armodafinil is not approved for use by anyone younger than 17 years old.

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