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Aprovel (Irbesartan)

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Aprovel is a prescription medicine used to treat the symptoms of high blood pressure (Hypertension), nerve pain caused by Type 2 Diabetes. Aprovel may be used alone or with other medications. Aprovel belongs to a class of drugs ARBs.

Other names for this medication:
Aprovel, Irbecard, Irbesartan, Irbesartana, Irbesartanum, Irbest, Irovel

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Also known as: Irbesartan


Aprovel is a perfect remedy in struggle against hypertension, kidney disease in patients with high blood pressure and type 2 diabetes and heart failure. Target of Aprovel is to lower high blood pressure. Aprovel acts by lowering high blood pressure. Aprovel is also known as Irbesartan, Approvel, Aprovel, Irovel, Karvea. Generic name of Aprovel is Irbesartan. Brand names of Aprovel are Aprovel, Avalide containing Irbesartan and Hydrochlorothiazide.


Usual Adult Dose for Hypertension:

Initial dose: 150 mg orally once a day Maximum dose: 300 mg orally once a day

Usual Adult Dose for Diabetic Nephropathy:

Target maintenance dose: 300 mg orally once a day

Use: Treatment of diabetic nephropathy with an elevated serum creatinine and proteinuria (greater than 300 mg/day) in patients with type 2 diabetes and hypertension.

Detailed Aprovel dosage information


If you overdose Aprovel and you don't feel good you should visit your doctor or health care provider immediately.


Store at room temperature between 15 and 30 degrees C (59 and 86 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children in a container that small children cannot open.

Side effects

The most common side effects associated with Aprovel are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not use potassium supplements or salt substitutes, unless your doctor has told you to.

Avoid getting up too fast from a sitting or lying position, or you may feel dizzy.

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Conformational Stability of the NH2-Terminal Propeptide of the Precursor of Pulmonary Surfactant Protein SP-B. Recent pharmacological, biochemical and immunohistochemical studies have revealed that tachykinins are the most likely transmitters at peripheral as well as central endings of primary sensory nerves. In both groups the median heart allograft survival was similar at around 26 days. The molecular basis of insulin-stimulated glucose uptake: signalling, trafficking and potential drug targets. Similar hormonal effects also influence the rate of glucose uptake from the small intestine. Furthermore, noise-driven attractor stabilization and switching were embodied by inhibitory connections. Cartilage tissue can be engineered by starting from a diversity of cell sources, including stem-cell based and primary cell-based platforms.

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Chromosomal polymorphism and wing size (as a measure of body size) were analysed simultaneously in two samples of Drosophila subobscura from Barcelona, Spain. Morphology was studied together with the condition of the local cell-bound immunity in 24 patients who were not exposed to occupational hazards in their occupations and in 32 miners with a long length of service. Genotype distributions were examined in 38 recipient-donor pairs (all chronic myelogenous leukemia in the first chronic phase) with either low-grade (grades 0-I) or high-grade (grades III-IV) aGVHD. Phylogenetic analyses were conducted using parsimony, distance, and likelihood criteria. In the present study, we determined the effect of an integrated health education and elastic band resistance training program on body composition, physical function, muscle strength and quality in community-dwelling elderly women. Increased first-week protein and energy intakes are associated with higher Mental Development Index scores and lower likelihood of length growth restrictions at 18 months in extremely low birth weight infants. These studies show improved delivery efficiency of IONPs following LPA administration.

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Indeed, tunicamycin reduces the expression of self-renewal regulator Sox2 at translation level. Elevated circulating levels and cardiac secretion of soluble Fas ligand in patients with congestive heart failure. Currently, the distribution of 20S proteasomes in eubacteria appears limited to the actinomycetes, while most other eubacteria contain a related complex of simpler structure. Neither sex, preoperative steroid dose, nor postoperative mean alternate-day steroid dose could be related to aseptic loosening. Fifty-two men and women identified as functionally illiterate, together with a group of control individuals of comparable age, sex, and socioprofessional background, produced a narrative intended for an absent recipient based on a sequence of pictures featuring a cast of 3 protagonists. Drug diffusion coefficient and clearance rates for the choroid and anterior chamber were varied. Bluetongue virus detection: a safer reverse-transcriptase polymerase chain reaction for prediction of viremia in sheep. Our data support the conclusion that ampullary cancers in elderly patients should be treated as aggressively as in younger patients.

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The purpose of this paper is to examine medication errors in Australian hospitals from a nursing perspective. Expression of the Francisella Pathogenicity Island (FPI) genes, which are required for intracellular proliferation, increased during the intracellular cycle. Autophagocytosis has a key role in cellular housekeeping by removing damaged organelles. Selection of high affinity ligands to hepatitis B core antigen from a phage-displayed cyclic peptide library. Patterns of ligand binding to normal, regenerating, preneoplastic, and neoplastic rat hepatocytes. Change in colon polyp size over time has not been well characterized. Hypophysitis has been histologically classified into five types: lymphocytic hypophysitis (LYH), granulomatous hypophysitis (GRH), xanthogranulomatous hypophysitis (XGH), xanthomatous hypophysitis (XH), and necrotizing hypophysitis.

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Injected at a dose of 4 or 10 mg/kg daily for 14 consecutive days, bromocriptine mesylate caused significant increases in plasma levels of total cholesterol, LDL cholesterol and total LDL whereas the levels of HDL cholesterol, total HDL triglycerides (TG) were reduced. We report a method for measuring the mean size of fine particles in a bulk state using the correlation properties of two speckle patterns. To maintain the soft tissue bed and esthetics, and to preserve mandibular function, immediate reconstruction was carried out with methyl methacrylate, the anatomical configuration of which was derived from the resected specimen. Generation of soluble recombinant human acute phase serum amyloid A2 (A-SAA2) protein and its use in development of an A-SAA specific ELISA. Evidence regarding the effects of medication organisation devices was limited, and the available evidence was susceptible to a high risk of bias. Using this analysis method, sets of typical audiograms have been obtained of sizes 12 and 60. Although pain and temperature sensation were absent, vibration and position sense were intact, showing anterior spinal artery syndrome. In particular, the role of troponin in identifying patients at risk of cardiotoxicity and of angiotensin-converting enzyme inhibitors in preventing cardiac dysfunction and cardiac events is clearly emerging as a new effective approach. These patients often develop frequent ascites and present with clinical signs and symptoms similar to cardiac tamponade (tachycardia, hypotension and dyspnea). The outcome variable, VA health service utilization, was prospectively assessed 1 year from the date of the initial PTSD assessment.

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Applications of immobilization of the mandible by nasomandibular wiring. Viral DNA can be detected by polymerase chain reaction (PCR) or hybridization procedures in patients sera or infected tissues. In spite of the apparent similarity between the chemical structures of the assayed compounds, the most active was approximately 200 times more cytotoxic than the least active. Specifically, capillary electrophoresis provides a convenient method for monitoring the removal of excess succinic anhydride/succinic acid and offers additional clues to the chemical nature of the impurities in these samples. The goal of this study was to assess the current practice and possible improvements of AD consultations by different professional groups in the Munich region in Germany compared to international Advance Care Planning (ACP) programs as best practice models. The analytical method we developed can detect levels as low as 0.1 mg of fiber in a 300 mg disk of KBr using a low cost IR spectrophotometer. Despite the observed protective effects, animals treated with IL-1 did not have increased numbers of blood leukocytes or peritoneal phagocytes prior to infection or at the times coincident with bacterial clearance. Their cognate ligands nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), neurotrophin-4 (NT-4), and neurotrophin-3 (NT-3) act as survival and trophic factors for neurons in the peripheral nervous system (PNS). Influence of loperamide on lactose handling and oral-caecal transit time. Adverse reactions possibly associated with the use of Emla cream.

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This hypothesis more completely describes the pathophysiology of the process, provides the basis for understanding the value and limitations of the techniques used for risk assessment and management, and helps clarify the potential endpoints and potential adverse effects of therapy to prevent arrhythmias. The new grading of the UICC distinguishes in addition to the well, moderately well and poorly differentiated carcinomas the undifferentiated tumors (G4). Porcine cysticercosis in southeast Uganda: seroprevalence in kamuli and kaliro districts. ERC with sphincterotomy was performed and gallstones obstructing the common bile duct were removed endoscopically. Our results for solid/solid phase transitions are consistent with those of Raman studies but the phase boundaries estimated in our calculations are at higher pressure than those inferred from spectroscopic data. In the present study we analyzed 266 spontaneously arising breast carcinomas for allelic losses in the BRCA1 and TP53 regions on chromosome 17, the BRCA2 region on chromosome 13, the ATM (mutated in ataxia-telangiectasia) region on chromosome 11 and on the chromosomal arms 7q and 16q. The development of quantized electron gas inside these nanocrystals is directly confirmed by STM observation of standing electron waves. Improvement of microscopical diagnosis of tuberculosis sputum by application of quicker centrifuges. Acute toxicity of organophosphorus insecticides to marine invertebrates. Infarctions of the greater omentum and of the epiploic appendages are rare etiologies of acute abdominal pain.

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Neuromas as the cause of pain in the residual limbs of amputees. T-cell-directed TAL-1 expression induces T-cell malignancies in transgenic mice. Tacrolimus concentrations in relation to CYP3A and ABCB1 polymorphisms among solid organ transplant recipients in Korea. Uptake to solid particles is generally slow, with observed uptake coefficients less than 1 x 10(-3), while uptake to liquid particles is around an order of magnitude more efficient. Clinica y diagnostico de la enfermedad de Pelizaeus-Merzbacher: descripcion de cinco casos. Four synthetic peptides (SP-1, SP-2, SP-3, and SP-4) combined with the phospholipid mixture displayed significant surfactant properties. Two days later, his blood pressure rose gradually and peripheral plasma renin activity showed more than 1,700 micro U/mL. All comparative studies which reported neonatal outcomes following waterbirth, and that were published since 1995, were included. The possible behavioural significance of the EAG-active compounds identified in human sweat samples is discussed.

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This review summarizes the response rates of these agents with an emphasis on recent findings, such as presentations from the 1998 Meeting of the American Society of Clinical Oncology. The results suggest that chronic C pneumoniae infection may be associated with the development of atherosclerotic coronary disease. The treatment of human myeloid cells with piceatannol suppressed TNF-induced DNA binding activity of NF-kappaB. Before transforming curricula, we must first obtain a comprehensive understanding of contemporary medical student microbiology education. The most common medications used were chlorphenamine, amitriptyline, diazepam, chlorpromazine, chlordiazepoxide and piroxicam. This work shows that useful metabolic information can be obtained on drug toxicity by the use of combined MAS-NMR and high-resolution NMR of liver spheroids and that such studies may enhance the validation of in vitro techniques against in vivo models for metabolic profiling. No statistically significant differences between either of the groups were found in overall psychological distress, intensity of the symptoms, or in numbers of self-reported symptoms in the Symptom Check List after controlling for age, sex, and education (Mean Global Severity Index 0.62 versus 0.63). Cytokines regulate proliferation and differentiation of hematopoietic progenitor cells. The binding of one such protein, the initiator protein TFII-I, to the initiation region of HIV-1 is augmented in the presence of Rel p50 and Rel p52 homodimers. Cytokine single nucleotide polymorphisms and consequent production levels have been associated with acute graft-vs-host disease (aGVHD) development.

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The high degree of homology between human and zebrafish Kv3.3 channels suggests that the zebrafish will be a useful model system for studying pathogenic mechanisms in SCA13. Hadassah, the Zionist organization of American women and its medical activities in Israel. Most importantly, proteosome inhibitors repress the TGFbeta inhibition of Muc4 expression. Comparison of suture-in and suture-out postkeratoplasty astigmatism with single running suture or combined running and interrupted sutures. This analysis, which has been previously published, is reviewed and enhanced with the mathematical equations for duplicating these relative risk calculations.

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However, whether CTLA-4 regulates responses to both self and foreign proteins is not clear. Although somatic oncogenic mutations of Ras genes are frequent in several cancer types, early investigations on gliomas revealed disappointing facts that the Ras mutations are nearly absent in malignant gliomas and that the BRAF mutations are present in a very small percentage of gliomas. The results from WCST show that COS patients have difficulty in executive functioning. Membrane tethering enables an extracellular domain of the acetylcholine receptor alpha subunit to form a heterodimeric ligand-binding site. The newly developed transurethral resection system was effective in a saline irrigated environment, which inhibited the obturator nerve reflex when applied in an animal model. Incidence of dentinal defects after root canal filling procedures.

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In contrast, none of the small cell carcinomas or carcinoid tumors of the lung were recognized by these antibodies. Examples are provided to illustrate several clinical challenges. Radiocontrast agents induce intense vasoconstriction in the renal medulla, which is hypoxic even in normal physiologic states, thereby aggravating the imbalance of medullary oxygen supply and demand. For alpha-lactalbumin, however, no such difference in the molecular areas for adsorbed and spread monolayer was observed indicating thereby that alpha-lactalbumin unfolded much more rapidly than beta-lactoglobulin. In the Lambert-Eaton myasthenic syndrome (LEMS), loss of the presynaptic voltage-gated calcium channels results in reduced release of the acetylcholine transmitter. Slow relaxation and solvent effects in the collapse of a polymer. The second largest cluster was situated in the left forceps minor, and the third largest cluster was in the right superior longitudinal fasciculus III. The short-term results are excellent, while long-term results with greater patient cohorts are awaited. Effects of legume consumption on serum cholesterol, biliary lipids, and sterol metabolism in humans. Furthermore, primary cultures of bovine corneal epithelial cells were transfected with Ad or chitosan-modified Ad in the absence or presence of anti-Ad antibodies.

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During the acute allergic reaction preformed mediators such as histamine, but also de novo produced mediators such as leukotrienes (LTC4/D4/E4) and prostaglandins (PGD2) are released. Psychobiological research on DID should include normal controls, preferably controls who are fantasy prone. Breast cancer is a heterogeneous disease with diverse prognoses. Two time frames were evaluated: from 1999 to 2001 and from 2009 to 2011. A scale with scores 1-3 was used to rate the quality of the reconstructed image of different hematoma as a subjective evaluation, and all the experimental data were processed with statistical treatment. Most of our knowledge is derived from NPC formation that occurs in dividing cells at the end of mitosis when the nuclear envelope (NE) and NPCs reform from disassembled precursors. Erythroid cell line KU812Ep6 was incubated with test sera before infection with B19 virus. Stereoselective synthesis of peptidomimetics based on acid-catalyzed ring-opening of beta-aziridinyl-alpha,beta-enoates. We confirm earlier results that the area over which spatial pooling takes place depends on the scale of the modulated pattern. Based on the clinical course and follow-up of their own EMP patients, the authors evaluated and reinvestigated all EMP cases cited in MEDLINE, Index Medicus, DIMDI (Deutsches Institut fur medizinische Dokumentation und Information, Cologne, Germany), and the reference lists of the publications found through these sources.

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When phosphorylation of Photosystem (PS) II core proteins is blocked in STN8 knock-out mutants of rice (Oryza sativa) under photoinhibitory illumination, the mobilization of PSII supercomplex is prevented. In the present study, PCNA immunohistochemical staining of 36 cases of oral cancer specimens obtained from surgery were investigated. Description of neurological symptoms and signs and findings in plain radiography (PR) and magnetic resonance imaging (MRI) of the cervical spine before and after treatment of the subaxial subluxation by traction and immobilisation with a Halo vest during four months. Septic arthritis caused by Corynebacterium amycolatum following vascular graft sepsis. Here we show how the human gut microbiome impacts the serum metabolome and associates with insulin resistance in 277 non-diabetic Danish individuals. Decreased interleukin-10 and increased interleukin-12p40 mRNA are associated with disease activity and characterize different disease stages in multiple sclerosis. maculicola, and also are expressed during response to the green peach aphid Myzus persicae. Alternatively, there may be differences in the rates of insertion of Alu elements.

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This study reconsiders the well-known link between gang membership and criminal involvement. The difference between these studies may reflect environmental variables. All patients received a subarachnoid block with local anaesthetic in addition to general anaesthesia. Early development of descending supraspinal pathways: a tracing study in fixed and isolated rat embryos. To observe the effects of inhaled Chuankezhi injection (CKZ) on airway inflammation in a mouse model of asthma and dilation of isolated guinea-pig airway smooth muscle in vitro, which can provide pharmacodynamic evidence for CKZ treating acute attack of asthma. CPI-1189 was well tolerated in HIV subjects with cognitive-motor disorder. Our results suggest that TNF-alpha and IFN-gamma are produced early after priming with C.

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An evaluation of the gestations of these children indicates that twin pregnancy per se was probably etiologic in the development of cortical visual impairment. Chitosan modification did not significantly change the particle size of Ad, but the surface charge of Ad increased significantly from -24.3 mV to nearly neutral. Dexfenfluramine: effects on food intake in various animal models. This study constitutes an encouraging first step in the assessment of receptor-mediated gene transfer as a technique for gene therapy in liver cancer. Determination of estrogen receptor in primary breast cancer using two different monoclonal antibodies, and correlation with its mRNA expression. Extracorporeal membrane oxygenation (ECMO) improves the outcome of refractory cardiogenic shock. As available limited therapeutic options fail to reduce the mortality associated with PH, alternative areas of therapy are worth exploring for potential drugs, which might be beneficial in PH. These data support the use of RFA in patients considered ineligible for surgery. haemolytica and the host response, there still remains a lack of detailed understanding. With regard to the forebrain structure examined, handling and forced swimming increased dialysate 5-HT in the amygdala.

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This article describes normal and abnormal radiographic presentations in both the recipient and donor sites after bone graft surgery. There were no incidences of complications or morbidity associated with the rib-sparing approach to internal mammary vessel harvest. AP5 in magnesium-free perfusion solution had qualitatively similar effects. NH4H2 PO4, which is a component of the bonding material in the investment, was present at a high concentration in the superficial layer of the agar impression material. The virus enters the ventricular system, and then travels caudally in the central canal of the spinal cord where ependymal cells are infected. Quantum dots laser desorption/ionization MS: multifunctional CdSe quantum dots as the matrix, concentrating probes and acceleration for microwave enzymatic digestion for peptide analysis and high resolution detection of proteins in a linear MALDI-TOF MS. Effects of castration on cost of zithromax 500 mg adrenergic, cholinergic and nonadrenergic, noncholinergic responses of isolated corpus cavernosum from rabbit. By using this model 36 traditional Chinese medical herbs from 28 families were studied. First, results of tests performed using a real machine generating vibration are illustrated.

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Only four studies have been published that examined the effects of hydration for stopping labor. When the host immune response induced against a local infection fails to contain it locally, it progresses to sepsis, severe sepsis, septic shock and death. Artificial miRNA processing and knockdown efficiency were analyzed by stem-loop RT-PCR, qRT-PCR, luciferase assay and target challenging. In addition, the nuclear accumulation and cytotoxicity of doxorubicin were significantly increased by encapsulation into the nanoparticles. Single SNPs were analyzed with a log-additive approach using logistic regression models adjusted for sex, age, Hispanic ethnicity, and race. Here, monoclonal mouse antibodies against the CD45 molecule expressed on rat lymphocytes (MAR anti CD45 Ab) were linked to lymphocytes, and as spacers, sheep anti-mouse antibodies (SAM Ab) were immobilized on silica surfaces, allowing the cells to stick to the floating hollow silica microbeads by simple incubation. Occurrence of adverse events following inadvertent administration of childhood vaccines. Some scientific reflections on possible mechanisms of general anaesthesia.

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Current strategies to preserve RKF also are reviewed, emphasizing those used in patients treated with peritoneal dialysis. The presence of cosolutes almost doubles the mass of surface aggregates and increases the rigidness of the aggregates for CTAB, consistent with a morphological change from cylinders to flat bilayers. In HBV hyperendemic areas, occult hepatitis B transfusion might not lead to HBsAg carriage or PTH. Multistep and single-step treatment of human spermatozoa with cryoprotectants. Photogeneration of free radicals from eumelanogenic intermediates and metabolites.

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A similar trend was also noted in patients after cardiac surgery. Our results suggest that the presence of two positively charged amino acids very early in the mature sequence interferes significantly with protein export. Subsequently, we performed quality appraisal consistent with the ISPOR checklist for retrospective database studies and accomplished comprehensive data extraction. Post-match disorder: how to cope when your program fails to match. A 4-month-old male with fulminant meningococcemia, refractory shock, and multiple organ failure. The SF/PLCL (50/50) nanofibrous scaffold facilitated norethindrone birth control pill hADSC proliferation and osteogenic differentiation in vitro and further promoted new bone formation in vivo, suggesting that the SF/PLCL (50/50) nanofibrous scaffold holds great potential in bone tissue regeneration.

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Thrombus of azelastine eye drop dosage instructions the right ventricle simulating a cardiac tumor--case report. Polymyositis and myasthenia are also known complications of D-penicillamine therapy. Physicians should advise families about healthful infant nutrition in order to lay the foundation for lifelong good health through a proper diet. Because this study is not an randomized test, it is difficult to compare the outcomes between the patients treated by radical cystectomy or by bladder preservation. The lack of a requirement for perfect matching means that there is an ever-increasing number of donors available.

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CCK(4) (3-30 microg/kg, i.p.) increased GABA outflow and induced objective signs of anxiety. The rab17 gene from maize is transcribed in late embryonic development and is responsive to abscisic acid and water stress in embryo and vegetative tissues. However, the reversal effect of SB203580 was not due to the suppression of IL-6 production because the SB203580 effect was still observed in the presence of exogenous IL-6. The rate of habituation was not influenced by carbohydrate content of the yogurt. This thoracoscopic cutting needle biopsy was easy to obtain a specimen for the frozened section diagnosis. The relevant sense organs were identified with Ss in a radial, earth-horizontal attitude. We conducted a prospective observational study of 221 patients presenting with acute dyspnoea at the emergency department. These findings are relevant for the use of antihypertensive therapy in postmenopausal women treated or not with hormone replacement therapy. The analytical formulas derived for the variances and covariances of the parameter estimation errors, validated by means of Monte Carlo simulations, allow quantitative predictions in terms of dipole depth, radius and span of the magnetometer system, signal-to-noise (SNR) ratio, and other parameters.

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