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Amrizole (Metronidazole)

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Amrizole eliminates bacteria and other microorganisms that cause infections of the reproductive system, gastrointestinal tract, skin, vagina, and other areas of the body. Antibiotics will not work for colds, flu, or other viral infections. This medication is sometimes prescribed for other uses; ask your doctor or pharmacist for more information.

Other names for this medication:
Aldezol, Amobin, Anazol, Anegyn, Aristogyl, Deflamon, Dequazol, Flazol, Gnostol, Grinazole, Mebadiol, Medazol, Metazol, Metral, Metris, Metrocev, Metrogel, Metrol, Metronidazole, Molazol, Nalox, Nidazyl, Norzol, Novazole, Orogyl, Padet, Promuba, Rodogyl, Rosalox, Servizol, Trichodazol, Trichozole, Vagizol, Zobacide, Zyomet

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Also known as: Metronidazole


Metronidazole injection is used to treat serious bacterial infections in different areas of the body. It is also used to prevent infections in the bowels before and after surgery for some patients.

Metronidazole belongs to the class of medicines known as antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.

This medicine is to be given only by or under the direct supervision of your doctor.


This section provides information on the proper use of a number of products that contain metronidazole. It may not be specific to Amrizole. Please read with care.

Use this medicine exactly as directed by your doctor. Do not use more of it, do not use it more often, and do not use it for a longer time than your doctor ordered.

This medicine is to be used only in the vagina. Use it at bedtime, unless your doctor tells you otherwise.

Do not get it into your eyes, nose, mouth, or skin. If this medicine does get into your eyes, wash them out right away with large amounts of cool tap water. If your eyes still burn or are painful, check with your doctor.

This medicine comes with a patient information leaflet and patient instructions. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Wash your hands with soap and water before and after using this medicine.

Nuvessa™ is available inside a prefilled applicator. The applicator is open at one end where you will insert the plunger and has a pink cap on the other end where the medicine will come out.

Vandazole® is in a tube. You will use an applicator to put the gel into your vagina. The applicator has a plastic tube called a barrel that is open at one end and has a plunger (another piece of plastic that can move inside the barrel) at the other end.

To use the medicine:

To fill the applicator: For cream or gel dosage forms: Nuvessa™: With the pink cap still on, push the tip of the plunger into the open end of the prefilled applicator. Pull the cap off before you insert the applicator into your vagina. Vandazole®: Break the metal seal at the opening of the tube by using the point on the top of the cap. Screw the applicator onto the tube. Squeeze the medicine into the applicator slowly until it is full. Remove the applicator from the tube. Replace the cap on the tube. For vaginal tablet dosage form: Place the vaginal tablet into the applicator. Wet the vaginal tablet with water for a few seconds. To insert vaginal metronidazole using the applicator: For all dosage forms: Relax while lying on your back with your knees bent (or in any position that you feel comfortable). Hold the full applicator in one hand. Insert it slowly into the vagina. Stop before it becomes uncomfortable. Slowly press the plunger until it stops. Withdraw the applicator. The medicine will be left behind in the vagina. Remove the applicator from your vagina. Use each applicator only once, and then throw it away.

To help clear up your infection completely, it is very important that you keep using this medicine for the full time of treatment, even if your symptoms begin to clear up after a few days. If you stop using this medicine too soon, your symptoms may return. Do not miss any doses. Also, continue using this medicine even if your menstrual period starts during the time of treatment.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For bacterial vaginal infections: For vaginal dosage form (cream): Adults—One applicatorful (500 milligrams [mg]), inserted into the vagina. Use the medicine 1 or 2 times a day for 10 or 20 days. Children—Use and dose must be determined by your doctor. For vaginal dosage form (gel): Nuvessa™: Adults and children 12 years of age and older—One applicatorful (5 grams [g]) inserted into the vagina once (at bedtime). Each applicatorful of Nuvessa™ contains 65 mg of metronidazole. Children younger than 12 years of age—Use and dose must be determined by your doctor. Vandazole®: Adults—One applicatorful (5 grams [g]) inserted into the vagina once a day (at bedtime) for 5 days. Each applicatorful of Vandazole® contains 37.5 mg of metronidazole. Children—Use and dose must be determined by your doctor. For vaginal dosage form (tablets): Adults—One 500 milligram (mg) tablet, inserted high into the vagina. Use the medicine once a day in the evening for 10 or 20 days. Children—Use and dose must be determined by your doctor.


If you overdose Generic Amrizole and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Generic Amrizole overdosage: dizziness, seizures, torpor, retching, nausea, lack of balance, problems with coordination, tingling.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Amrizole ER dosage information

Side effects

The most common side effects associated with Amrizole are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

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Nitrosyl haemoglobin is increased in patients with Type I diabetes. ATRAP interacts specifically with the carboxyl-terminal domain of the AT1a receptor but not with those of angiotensin II type 2 (AT2), m3 muscarinic acetylcholine, bradykinin B2, endothelin B, and beta2-adrenergic receptors. All predation events occurred in forest-edge or plantation habitat. BVD-virus infection in goats-experimental studies on transplacental transmissibility of the virus and its effect on reproduction. Three successful pregnancies following natural conception over an 8-year time span despite serum follicle stimulating hormone level greater than 15 mIU/ml. Annually as a result of suicide, almost one million people are killed and many more unsuccessful attempt to take his own life. The intraclass correlation coefficient (ICC) for interobserver variability was assessed. Features of the several entities currently recognized are described in this overview. The comprehensive health status was accorded utility scores, and comparisons were made with health status measurements of the general population. However, experiments indicate the existence of a mechanism for organization of a centered microtubule array that is independent of the centrosome.

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CT-MRI image fusion technique provides valuable supplements to CT technology for more precise targeting of the prostate cancer. Such tumors usually present with signs and symptoms of bronchial obstruction. Long-term follow-up of patients with spinal cord injury with a new ICF-based tool. Synthesis and structure-activity relationships of a series of aminopyridazine derivatives of gamma-aminobutyric acid acting as selective GABA-A antagonists. The method was developed on the enclosed Shandon Pathcentre, and the quality of specimens reported here will be reproduced only if carried out on a similar processor under the same environmental conditions. Subcortical-cerebellar-spinal domain of ANQ was found to be associated with cognitive style and executive functions. Pestis redux: the initial years of the third bubonic plague pandemic, 1894-1901. In contrast, the alpha 1-subunit of the adult-type glycine receptor heteromeric complex was detectable only at later stages of development, after embryonic day 16, suggesting a change in the subunit composition of some glycine receptor complexes.

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The effect of dietary fats on serum cholesterol is widely assumed to be due solely to the fatty acids and cholesterol they contain. Negative regulation of the gene for the preprothyrotropin-releasing hormone from the mouse by thyroid hormone requires additional factors in conjunction with thyroid hormone receptors. We report a mentally retarded female, known to have trisomy 8, who presented with stiffness of her elbow joints and no history of preceding trauma. Spoilage of fresh and lightly preserved fish products is caused by microbial action. The effect of HSV-1 infection in the epidermis on the expression of genes for nitric oxide synthase (NOS) and interleukin-1 beta (IL-1 beta), and the ability of OK-432 to alter this effect were studied. A low concentrated gadolinium flush in comparison to a pure saline flush improves significantly vessel contrast and their delineation in time-resolved CE-MRA using the keyhole technique. Correlations between the length of hospital stay and age, gender, NLR, c-reactive peptide levels (CRP), the appendix diameter on CT or ultrasonogra-phy, appendix localisation and pathology reports were evaluated. Moreover, the expression level of p21 protein was upregulated, whereas Bcl-2 and dysfunctional p53 protein were downregulated, which also contributed to 2-ME2-induced apoptosis. The sooner the treatment began after the onset of symptoms, the more dramatic was the response.

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Prospective cohort studies and controlled clinical trials of children with ventilation tubes, with a minimum follow-up of 2 months. The potential for improvements in the technology are substantial, and data from second-generation assays have already been reported. The resulting collection of five mutations, each inactivating a single site, was analyzed for effects on covalent modification at the remaining sites on Trg and for the ability of the duphaston tab altered proteins to mediate sensory adaptation. Structure and evolutionary origin of the gene encoding mouse NF-M, the middle-molecular-mass neurofilament protein. Myofibroblast proliferation is a central feature of pulmonary fibrogenesis.

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