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Amizep (Amitriptyline)

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Amizep is sometimes used off-label, meaning not FDA approved, for certain conditions. Some providers will use this medication to treat nerve pain. This can be helpful for people who have diabetes or fibromyalgia and haven't felt relief with other medications.

Other names for this medication:
Abamax, Amicon, Amicure, Amitin, Amitone, Amitrac, Amitrim, Amitrip, Amitryn, Amitryptyline, Amiwel, Amrea, Amtran, Amypres, Anitryp, Aptric, Axtrip, Chlotrip, Emotrip, Endep, Latilin, Limbitrol, Limbival, Maxitrip, Mitrip, Nextrip, Raitrip, Sereval, Tablin, Tadamit, Trixide, Tryptomec, Typlin

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Also known as: Amitriptyline


Amizep (amitriptyline) is a tricyclic antidepressant with sedative effects. Amitriptyline affects certain chemical messengers (neurotransmitters) that communicate between brain cells and help regulate mood.

Amizep is a prescription medicine used to treat symptoms of depression.


Usual Adult Dose for Depression:

OUTPATIENTS: -Initial dose: 75 mg orally per day in divided doses; this may be increased to 150 mg/day (if needed) -Maintenance dose: 40 to 100 mg orally per day -Maximum dose: 150 mg/day Alternate outpatient treatment regimen: 50 to 100 mg orally as a single dose at bedtime; this may be increased by 25 or 50 mg as needed at bedtime to a total of 150 mg/day INPATIENTS: -Initial dose: 100 mg orally per day -Maintenance dose: 40 to 100 mg orally as a single dose at bedtime -Maximum dose: 300 mg/day Comments: -Dose increases should preferably be made in the late afternoon or at bedtime due to the sedative effect. -The full therapeutic effect may take as long as 30 days to develop. -Maintenance doses should be reduced to the lowest amount that will maintain relief of symptoms when satisfactory improvement has been obtained. -Maintenance therapy should be continued for 3 months or longer to lessen the possibility of relapse. Use: Relief of symptoms of depression

Usual Geriatric Dose for Depression:

10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Elderly patients should be monitored carefully and serum levels obtained as clinically appropriate. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Usual Pediatric Dose for Depression:

12 years or older: 10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Detailed Amizep dosage information


If you overdose Amizep and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Amizep overdosage: seizures, loss of consciousness for a period of time, seeing things or hearing voices that do not exist, agitation, feeling drowsy, rigid muscles, vomiting, high temperature, cold body temperature, problems concentrating, abnormal heartbeats, confusion.


Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Amizep are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Amizep if you are allergic to Amizep components. Do not take Amizep if you are pregnant, planning to become pregnant, or are breast-feeding. Be careful with Amizep if you suffer from or have a history of a history of heart attack, stroke, bipolar disorder (manic-depression), schizophrenia or other mental illness, diabetes, overactive thyroid, glaucoma, problems with urination, heart disease, seizures. Be careful with Amizep if you are taking guanethidine (Ismelin), disulfiram (Antabuse), heart rhythm medications such as flecainide (Tambocor), propafenone (Rhythmol), quinidine (Cardioquin, Quinidex, Quinaglute), cimetidine (Tagamet). Avoid alcohol. Be careful! Taking Amizep you can become suicidal. Be careful when you are driving or operating machinery. Be careful with Amizep if you are going to have a surgery. It can be dangerous to stop Amizep taking suddenly.

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D0870, at doses of 0.5 and 2.5 mg/kg of body weight given once over the course of a 10-day infection, was effective in eradicating vaginitis caused by fluconazole-susceptible laboratory and clinical isolates, respectively. Estimation of Ki in a competitive enzyme-inhibition model: comparisons among three methods of data analysis. Activity and stability of recombinant human superoxide dismutase in buffer solutions and hypothermic perfusates. Type 2 Diabetes mellitus (T2DM) affects persons of all ages, while also placing heavy economic burdens on national economies and healthcare systems. In vitro toxicity testing of implantation materials used in medicine: Effects on cell morphology, cell proliferation and DNA synthesis. Application of this technology should lead to new rapid methods for high throughput screening and delineation of the interactome of cells. Three subtypes have been distinguished (beta1-, beta2-, and beta3-adrenoceptors).

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The purpose of this study was to review the FES experiences in a tertiary referral center between January 1997 and February 2008. We present the first experimental demonstration of compatible single-sideband (compatible-SSB) modulated OFDM optical system at 11.1Gb/s data rate for long distance transmission over 675 km uncompensated standard single-mode fiber. The fact that some chlorophenols form the same supramolecular structures as those described previously for structurally nonrelated surfactants sheds light on the mechanisms of self-assembly. The mass was tender to palpation, but the size was too tiny to detect. In contrast, reentrainment to green and yellow light was abolished in the cry, Rh1, Rh5 and Rh6 quadruple mutant, and remarkably slowed in the cry, Rh1 and Rh6 triple mutant. However, SLNB after NAC results in a lower identification rate and a higher FNR than SLNB before treatment. The impact of crown-rump length measurement error on combined Down syndrome screening: a simulation study. In particular, we focus on young women as a key population in need of HIV prevention and highlight factors that increase their risk on several levels. Forskolin, glucagon, cholecystokinin, and carbamylcholine were able to lower the threshold and increase the extent of insulin release.

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Limits of parallel processing: excitatory convergence of different information channels on single neurons in striate and extrastriate visual cortices. Compared with adult silver foxes, higher values were observed in serum levels of triglyceride, phospholipid, beta-lipoprotein, blood urea nitrogen and total protein. We tagged newly synthesized proteins by incorporation of the noncanonical amino acid azidohomoalanine and visualized them with fluorescent noncanonical amino acid tagging (FUNCAT). The influence of different metal-chelate conjugates of pentixafor on the CXCR4 affinity. A major aim of neurobiology today is to improve understanding of the signaling pathways that couple rapid events, such as the action potential and neurotransmitter release, to long-lasting changes in synaptic strength and increased neuronal survival. Effects of mating dynamics and crowding on sex ratio variance in mice. The Harderian gland is an orbital feature found in most terrestrial vertebrates.


The incidence and mortality of UGIB overall and ulcer bleeding decreased significantly, and the decline of incidence occurred only in patients younger than 70 years old. Conformation-dependent hydride transfer in neuronal nitric oxide synthase reductase domain. The activities of c-Jun to stimulate unwinding and origin binding of LT were found to be harbored within the N-terminal region of c-Jun, which is distinct from the DNA binding domain. Mustard vesicants alter expression of the endocannabinoid system in mouse skin. Adenosine has been shown to reduce infarct size predominantly during reperfusion by adenosine A2-receptor-mediated processes.

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Alcohol, acetaldehyde and salsolinol-induced alterations in function and metabolism of cerebral GABAergic and cholinergic neurons: possible involvements in alcohol dependence and withdrawal. AbetaPP induces cdk5-dependent tau hyperphosphorylation in transgenic mice Tg2576. ACE activity in the lavage fluid (LACE) was correlated with the number of alveolar macrophages in controls, indicating that it may come from these cells. Stable carbon and nitrogen isotopes were analysed on bone collagen of 43 Sudanese Nubians from the X-Group period to test dietary hypotheses for the high frequency of osteopenia in this population. The data suggested that alpha 1PI does not inhibit elastase bound to alpha 2M but sterically hinders the complex. The objectives of the present study were to determine whether chemokine expression is increased during renal transplant rejection. We also show that inclusion of in vitro assays would not improve the accuracy of the model. Studies from multiple laboratories with a range of methods raised the possibility that insulin production occurs naturally at extrapancreatic sites. It can be concluded that radiology can contribute substantially to the morphodynamic assessment of patients with dysfunction of a Kock ileostomy whereas endoscopy easily depicts mucosal lesions. The data were submitted to Friedman nonparametric test to analyze the comparisons among observation periods and to allow the comparison among groups.

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Originality/value - The authors focus on the measurement of the whole healthcare production system and try to avoid sub-optimization. Within this review, current findings regarding gender differences in OSA polysomnographic features and demographic factors, symptom presentation, functional status, comorbidities, health care utilization, and therapeutic management have been reviewed. When the locomotor balance function and the slow-phase eye velocity of the spontaneous nystagmus were analyzed, the ACTH-(4-10) groups compensated significantly faster than the control group (p less than 0.05). The hepatitis C virus RNA-dependent RNA polymerase membrane insertion sequence is a transmembrane segment. The concepts of spinal inhibition and reflex action arose from 19th-century neurophysiological experimentation.

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Depolarization-activated calcium channels shape the calcium signatures induced by low-temperature stress. A clear hexagonal LEED pattern confirmed the presence of a quite large grain of Ti(0001) on the substrate while no new superstructure was formed after deposition of MgCl(2) either at room or at elevated temperatures. In this work, a method named as linear model correction (LMC) is proposed for calibration transfer without standard samples. It is proposed that the prolonged modulations of the micturition reflex represent physiological adaptive processes, which preserve a flawless function of the bladder during life. In contrast, if ERK-mediated phosphorylation is increased by transfection of a constitutively active MEK1 mutant, receptor internalization is inhibited. Risk Factors of Hepatotoxicity During Anti-tuberculosis Treatment.

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One gene causing AD-FSP (FSP1) has recently been mapped to chromosome 14q, another gene (FSP2) to chromosome 2p, and a third gene (FSP3) to chromosome 15q. LC-MS analysis of low molecular weight organic acids derived from root exudation. Human HSF-1 cDNA was cloned into a retroviral vector (pvhhsf-1) and was overexpressed in a murine fibroblast cell line. Furthermore, the cleavage specificity of the CylA activator is reported and it is shown that proteolytic activation of both subunits is essential for activity. Complete spinal transection resulted in a marked potentiation of pentobarbital-induced TF inhibition, demonstrating a spinal locus of action. Assay of G protein-coupled receptor kinase activity by rhodopsin phosphorylation. Prognostic impact of second cancer on the survival of early breast cancer patients. Embryo-uterine interactions leading to the attachment reaction is followed by stromal cell proliferation and differentiation into decidual cells (decidualization) at the sites of blastocyst apposition.

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Gastrointestinal Manifestations of Cystic Fibrosis in Adolescence. In order to identify the receptors of JCV, we generated virus-like particles (VLP) consisting of major viral capsid protein VP1. Inhalation of dry powder mannitol improves clearance of mucus in patients with bronchiectasis. We conclude that HVEM interacts directly with gD, suggesting that HVEM is a receptor for virion gD and that the interaction between these proteins is flomax 40 mg a step in HSV entry into HVEM-expressing cells. Contribution of the intracellular domain of murine Fc-gamma receptor type IIB1 to its tumor-enhancing potential. Communicating with the people about HIV infection risk as a basis for planning interventions: lessons from the Kagera Region of Tanzania.

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Association of parental history of type 2 diabetes mellitus with leptin levels in Jordanian male youths. While progestagenic effects of T and DHT required relatively high concentrations (microM levels), the synthetic androgens stimulated AP activity at nM or pM levels. The position of the New York Academy of Medicine on physician-assisted suicide. Secondary outcomes were length of intensive care unit stay, length of hospital stay, overall mortality, total doses of sedative and analgesic medicines and Ramsay scores and duration of cessation of sedative infusions per day. Attachment of a noninvasive enteric pathogen, enteropathogenic Escherichia coli, to cultured human intestinal epithelial monolayers induces transmigration of neutrophils. It is not clear how they interact with tissue metabolism, although it has been proposed that induced currents or electric fields impinging on cell membranes may modify their ion transport function. This study aimed to investigate the relationship between the amount of sexting, psychological distress, and dating violence in adolescents and young adults.

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