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Amitrim (Amitriptyline)

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Amitrim is a tricyclic antidepressant. Different doses of this medicine help in treating and preventing different problems such as depression, neuropathic pain, and migraine. Amitrim is normally taken before bedtime because it can make you feel sleepy.

Other names for this medication:
Abamax, Amiclozor, Amicon, Amitar, Amitone, Amitop, Amitrim, Amitrol, Amitwix, Amiwel, Amixide, Amoten, Amsha, Amtipax, Amtran, Amypres, Anitryp, Aptric, Arpidox, Axtrip, Bluneel, Cotrip, Crypton, Emotrip, Endep, Eptanol, Estiline, Libral, Librodep, Limbitrol, Limbival, Lodep, Maxitrip, Mitrip, Mitryp, Nextrip, Relidep, Ristryl, Sereval, Tablin, Teedep, Tridep, Tryline, Tryptomec, Typlin

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Also known as: Amitriptyline


Amitrim (amitriptyline) is a tricyclic antidepressant with sedative effects. Amitriptyline affects certain chemical messengers (neurotransmitters) that communicate between brain cells and help regulate mood.

Amitrim is a prescription medicine used to treat symptoms of depression.


Usual Adult Dose for Depression:

OUTPATIENTS: -Initial dose: 75 mg orally per day in divided doses; this may be increased to 150 mg/day (if needed) -Maintenance dose: 40 to 100 mg orally per day -Maximum dose: 150 mg/day Alternate outpatient treatment regimen: 50 to 100 mg orally as a single dose at bedtime; this may be increased by 25 or 50 mg as needed at bedtime to a total of 150 mg/day INPATIENTS: -Initial dose: 100 mg orally per day -Maintenance dose: 40 to 100 mg orally as a single dose at bedtime -Maximum dose: 300 mg/day Comments: -Dose increases should preferably be made in the late afternoon or at bedtime due to the sedative effect. -The full therapeutic effect may take as long as 30 days to develop. -Maintenance doses should be reduced to the lowest amount that will maintain relief of symptoms when satisfactory improvement has been obtained. -Maintenance therapy should be continued for 3 months or longer to lessen the possibility of relapse. Use: Relief of symptoms of depression

Usual Geriatric Dose for Depression:

10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Elderly patients should be monitored carefully and serum levels obtained as clinically appropriate. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Usual Pediatric Dose for Depression:

12 years or older: 10 mg orally 3 times a day AND 20 mg orally once a day at bedtime Comments: -The full therapeutic effect may take as long as 30 days to develop. -Dose adjustments should be made according to clinical response. Use: Relief of symptoms of depression

Detailed Amitrim dosage information


If you overdose Amitrim and you don't feel good you should visit your doctor or health care provider immediately. Symptoms of Amitrim overdosage: seizures, loss of consciousness for a period of time, seeing things or hearing voices that do not exist, agitation, feeling drowsy, rigid muscles, vomiting, high temperature, cold body temperature, problems concentrating, abnormal heartbeats, confusion.


Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture and heat. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Amitrim are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Do not take Amitrim if you are allergic to Amitrim components. Do not take Amitrim if you are pregnant, planning to become pregnant, or are breast-feeding. Be careful with Amitrim if you suffer from or have a history of a history of heart attack, stroke, bipolar disorder (manic-depression), schizophrenia or other mental illness, diabetes, overactive thyroid, glaucoma, problems with urination, heart disease, seizures. Be careful with Amitrim if you are taking guanethidine (Ismelin), disulfiram (Antabuse), heart rhythm medications such as flecainide (Tambocor), propafenone (Rhythmol), quinidine (Cardioquin, Quinidex, Quinaglute), cimetidine (Tagamet). Avoid alcohol. Be careful! Taking Amitrim you can become suicidal. Be careful when you are driving or operating machinery. Be careful with Amitrim if you are going to have a surgery. It can be dangerous to stop Amitrim taking suddenly.

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For example, by detecting where connection patterns change, one can define anatomical borders between cortical regions or subcortical nuclei in the living human brain for the first time. The inclusion behavior of cis-cyclooctene, cis, cis-1, 3-cyclooctadiene and cis, cis-1, 5-cyclooctadiene with beta-cyclodextrin (beta-CD) was studied by using (1)H NMR method in D(2)O/CD(3)OD solution and PM3 quantum-chemical simulation in vacuum. In a recent work it has been shown that in urodeles the activation of L-type calcium channels is sufficient to trigger neural induction. To elucidate contribution of left ventricular hypertrophy (LVH) vs myocardial ischemia to rhythmic disorders in patients with essential hypertension (EH) and LVH. Inducible NOS was constitutively expressed in the pregnant uterus (smooth muscle and epithelia) and placenta (sinusoids and macrophages) but was absent in the nonpregnant state as determined by RT-PCR and immunohistochemistry.

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Evaluation of a bioreactor with stacked sheet shaped organoids of primary hepatocytes. Anti-inflammatory activity and neutrophil reductions mediated by the JAK1/JAK3 inhibitor, CP-690,550, in rat adjuvant-induced arthritis. A retrospective review was performed in patients with biliary obstruction who underwent EUS-BD or PTBD after failed ERCP from June 2010 through December 2014 at a single tertiary care center. For amplification and detection of influenza RNA, all molecular assays evaluated were based on real-time PCR. Microbial metabolites emerge as key messengers in the complex communication between the gut microbiota and their host. Ion-damaged germanium shows a significant decrease in photoresponsivity with implant dose, particularly with doses exceeding the critical amorphizing dose (D(c) approximately 1 x 10(14) cm(-2)). Nonhealing wounds, necrotizing infections, radiation-induced necrosis, crush injury, decompression illness, and CO poisoning all exhibit impaired tissue oxygenation. EP4 receptor gene expression, on the other hand, was detected in the intestinal mucosal layer. PET in radiotherapy planning: particularly exquisite test or pending and experimental tool?. Increased expression of ALDH1, EZH2 and KI67 are found to be associated with unfavourable prognosis in patients with astrocytic gliomas and may predict therapeutic modalities.

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Development of a flow cytometry assay for the identification and differentiation of chemicals with the potential to elicit irritation, IgE-mediated, or T cell-mediated hypersensitivity responses. The testes in different groups of whitethroated munia (Lonchura malabarica) were studied following exogenous treatment of testosterone propionate (1 mg/100 g body wt./day) at 06.00 h or 14.00 h or 22.00 h for 15 consecutive days during the quiescent phase of the annual testicular cycle. Modifiable Risk Factors in Total Joint Arthroplasty: A Pilot Study. The incubation of total cellular RNA and nuclear DNA isolated from lymphocytes with CrCl3 and K2Cr2O7 yielded a binding of 1.1-1.6 fold more of Cr atoms to RNA than to DNA. In this compartment, both spectrin forms may be metabolized in vivo, at least in part, by calcium-activated proteolysis. This study tested a convenient way to increase PA among type 2 diabetes patients. The Francis method was used to detect data saturation and thereby identify sample size. Thus, these structures support only a T left and right arrow R left and right arrow R2 allosteric pathway and underscore the physiological importance of the R2 conformation. Targeted interventions may be necessary to improve infant feeding practices in mothers who reside in urban areas, are more educated, and are from wealthier households.

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A 54-year-old female with chronic hepatitis C developed severe thrombocytopenia after a single administration of Peg-IFN alpha 2a subsequent to 48 weeks of Peg-IFN alpha-2b plus ribavirin therapy. Many studies have demonstrated that honey has antibacterial activity in vitro, and a small number of clinical case studies have shown that application of honey to severely infected cutaneous wounds is capable of clearing infection from the wound and improving tissue healing. Supramolecular vs Electronic Structure: The Effect of the Tilt Angle of the Active Group in the Performance of a Molecular Diode. The Ten Most Commonly Asked Questions about Platelet Glycoprotein IIb/IIIa Receptor Antagonists. To investigate the protective effects against ischemia reperfusion injury of dipyridamole in a model of induced priapism in rats. Taken together, the data suggest that GM-CSF could upregulate the LTR-driven transcription of HIV-1 through modulation of NF-kappaB and SP1 by multiple signalling pathways. Three HPLC peaks were found to be immunoreactive, in hemolymph extracts of both sexes. Because hydrodynamic friction takes place at the molecular surface, another possibility is to use shell models, as originally proposed by Bloomfield.

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Ten months after stopping tamoxifen, we diagnosed a stage Ic granulosa cell tumor of the ovary. A scoping review explored the extent, range and nature of three types of physical activity-related evidence available in reviews: (I) health outcomes/risk factors, (II) interventions and (III) policy-making. Although we have demonstrated that regression models do not perform better than previous costs in predicting future short term costs, previous costs are a much less informative predictor than health status variables. Clinical versus fundus photographic evaluation of the status of cytomegalovirus retinitis in AIDS patients. Intravital two-photon microscopy revealed that siP53 significantly ameliorated structural and functional damage to the kidney assessed by quantification of tubular cast formation and the number of apoptotic and necrotic tubular cells and by evaluation of blood flow rate. To determine if a secondary center of ossification (SCO) of the anconeal process is present in skeletally immature dogs that do not develop an ununited anconeal process (UAP). Association between interleukin-21 gene polymorphisms (rs12508721) and HBV-related hepatocellular carcinoma. Relationship between molecule structures and their spasmolytic and analgesic activities. Augmented expression of gamma-glutamyl transferase 5 (GGT5) impairs testicular steroidogenesis by deregulating local oxidative stress. Recombinant adeno-associated virus (rAAV) vectors provide excellent gene delivery into the kidney in several mammals.

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Changes in the incidence and duration of periods without insurance. Twenty-eight New Zealand rabbits were randomly separated into four groups. An inhibition of transcription by alpha-amanitin did not block the Csb-dependent repair in ogg1(-/-) fibroblasts. Localization of retina/pineal-expressed sequences: identification of novel candidate genes for inherited retinal disorders. The Medpor implant was shaped precisely based on the deficiency model and implanted with dermis-fat graft at the same stage. Interrater agreement in the measurement of QRS interval in tramadol p tablet uses in tamil tricyclic antidepressant overdose: implications for monitoring and research. The results show how the parameters measured with the functional techniques (fluorophotometry, pachymetry) generally become normal after the surgical trauma, while the endothelial cell count remains irreversibly altered.

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The tumor with a cribriform pattern reacted strongly with PSA but did not react with mAbDas1. The 25.3 kb element is self-transferable to various Gram-positive bacterial genera where it transposes. The principle advantage of this technique is that it allows, in a single RNA sample, the simultaneous measurement of the relative levels of at least six mRNA species, including that of flagyl yeast infection side effect a control mRNA. Antiphospholipid antibodies (APL) and annexin V have an affinity for anionic phospholipids, so it has been hypothesized that one of the thrombotic mechanisms of APL may be due to displacement of annexin V from phospholipid surfaces. Surgical treatment of superior vena cava syndrome caused by thoracic cancers.

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Simultaneous anterior decompression and posterior instrumentation of the tuberculous spine using an anterolateral extrapleural approach. The implementation of a computerized scheduling and management system for the operating room is evaluated. The PDE is defined on a computational domain with a moving boundary, which is part of the solution. Antidromic stimulation of the medulla showed that all P-cells examined projected their axons to the ipsilateral ventrolateral medulla. These constraints guide the dynamic generation of potential query amiloride brand name in philippines plans. To investigate the association between the magnitude of foetal movements and level of prenatal attachment within a 24h period among women in the third trimester of pregnancy.

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Effect of a selective 5-HT reuptake inhibitor in combination with 5-HT1A and 5-HT1B receptor antagonists on extracellular 5-HT in rat frontal cortex in vivo. Phase-resolved two-dimensional spectroscopy based on collinear n-wave mixing in the ultrafast time domain. cDNA clones encoding six cytosolic small heat shock proteins (sHSPs) were identified using differential screening. To ascertain whether laminitis can be induced via administration of oligofructose (OF) at doses of 5.0 and 7.5 g/kg in horses and to assess glucose and insulin dynamics before and after treatment. The simple and relatively inexpensive method presented herein allows for convenient analysis of sequence variation in DRD5 and can be easily adapted to other duplicated genomic regions in order to obtain good quality sequence data. This provides more diagnostic information concerning acute myocardial infarction and other muscle diseases than is available from routine CK isoenzyme analysis.

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Cerebellar activation during classical conditioning of the human flexion reflex: a PET study. Here, we show that Xdpcp (Xenopus dok-PTB containing protein) has a pivotal role in regulating mesendoderm formation in Xenopus, and negatively regulates the activin/nodal signaling pathway. In addition, apoptotic molecules may serve as surrogate molecular markers of tumor response to IL-13R-directed cytotoxin therapy. Modifications on Tyr-3 or/and Tyr-63 of PLA2 resulted in the complete loss of its ability to enhance the ANS fluorescence. The optimal diagnostic excitation wavelengths identified using this model - 350-370 nm excitation and 400-450 nm excitation - are similar to those identified for detection of human oral cavity neoplasia.

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Two new species of the genus Centromacronema Ulmer 1905 (Hydropsychidae: Macronematinae) from Brazil. Three medication preparation areas were created to mimic a hospital setting. Moreover, similar response occurred in cells transiently transfected to express SidI. More research is needed to identify the stressors of all primary brain tumor patients and their caretakers and integrate appropriate interventions to improve health-related quality of life in both groups. The presence, type, and location of cracks were registered by a blinded observer, with the scanning electron microcopy serving as the reference. In multicellular organisms, there is a potential risk that cheating mutants gain access to the germline.

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