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Amiodarex (Amiodarone)

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Amiodarex is a class III antiarrhythmic indicated for the treatment of recurrent hemodynamically unstable ventricular tachycardia and recurrent ventricular fibrillation. The FDA approved indications for Amiodarex are recurrent ventricular fibrillation (VF) and recurrent hemodynamically unstable ventricular tachycardia (VT). Off-label indications include atrial fibrillation and supraventricular tachycardia.

Other names for this medication:
Amidrone, Amiobal, Amiocar, Amiodacore, Amiodarex, Amiodaron, Amiodarone, Amiohexal, Amiotach, Angoron, Angoten, Aratac, Asulblan, Atlansil, Braxan, Cardiodarone, Cardiron, Cordalin, Cordan, Cordarex, Cornaron, Coronal, Coronax, Daritmin, Diarona, Escodaron, Eudarona, Eurythmic, Kendaron, Keritmon, Miocor, Miodar, Miodrone, Mioritmin, Miotenk, Nexterone, Novarona, Opacorden, Pacerone, Rhythmiodarone, Rithmik, Ritmocardyl, Rivodaron, Rivodarone, Sedacoron, Tiaryt, Trangorex

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Also known as: Amiodarone


Amiodarone injection is used to correct life-threatening heart rhythm problems called ventricular arrhythmias. This medicine is used in patients who have already been treated with other medicines that did not work.

Amiodarone injection belongs to the group of medicines known as antiarrhythmics. It works directly on the heart tissue and will slow the nerve impulses in the heart. This helps keep the heart rhythm normal.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain amiodarone. It may not be specific to Amiodarex. Please read with care.

You will receive your first dose of this medicine in the hospital. Your doctor will watch you closely after you take this medicine to make sure you do not have any serious side effects.

Take this medicine exactly as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. Do not miss any doses. It may also take 1 to 3 weeks before your body responds to this medicine.

This medicine should come with a Medication Guide. Read and follow these instructions carefully. Ask your doctor if you have any questions.

You may take this medicine with or without food, but take it the same way each time.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage form (tablets): For ventricular arrhythmias: Adults—At first, 800 to 1600 milligrams (mg) per day taken in divided doses. Your doctor may adjust your dose as needed and tolerated. Children—Use and dose must be determined by your doctor.


If you overdose Amiodarex and you don't feel good you should visit your doctor or health care provider immediately.


Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F) away from moisture, light and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Amiodarex are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

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The aim of this study was to evaluate the clinical application of the American College of Cardiology Foundation and American Society of Echocardiography appropriateness criteria for stress echocardiography (SE) in a single-center university hospital. Two SNAP-25 genetic variants in the binding site of multiple microRNAs and susceptibility of ADHD: A meta-analysis. These experiments, aimed at eliciting a state of differential gain, were specifically designed to adapt only the saccadic response, since targets were shifted along corresponding iso-vergence circles. The objective of this article is to review published studies to describe issues and quality of evidence surrounding assistive technology (AT) use by the baby boomer generation. Microneurographic recordings suggest that hypertensive reactions in patients with cervical spinal cord lesions usually are due, not to exaggerated sympathetic nerve reactions, but rather to the combination of more diffuse sympathetic nerve activation than normally, exaggerated vascular reactions and absence of blood pressure restraining reflexes. Characteristics of lifetime factors, bone metabolism, and bone mineral density in patients with hip fracture. However, intradermally inoculated hamsters presented a robust Th1-like immune response, characterized by high levels of INF-gamma and TNF-alpha cytokines, detected in the liver of animals challenged with virulent trophozoites. Thus, there was not a simple relationship between the kinetics and the dynamics of (R)-8-OH-DPAT. The incidence of more severe injuries following road traffic accidents with registered motor vehicles was constant during the period. Here 1 perform a comparative analysis using independent contrasts to show that social pressures have favored an extension in the proportion of time primates spend as juveniles.

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We report two cases with successful ablation of left-sided accessory pathways and premature ventricular contractions from mitral annulus with one ablation. HIV-1 protease specificity of peptide cleavage is sufficient for processing of gag and pol polyproteins. Computer assisted surgery of the distal humerus can employ contralateral images for pre-operative planning, registration, and surgical intervention. To extract the desired information, complementary simulations of the scattering process are inevitable. One prominent example of RNA-based regulatory components is riboswitches, genetic elements that mediate ligand control of gene expression through diverse regulatory mechanisms. A multicenter survey was conducted between 2008 and 2009 in 35 NICUs. This study aimed to investigate the efficacy of FIRM as a stand-alone procedure for the treatment of paroxysmal AF.

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Since the pressure-volume relationship of cardiac ventricles is not linear and shows great variability, filling of the ventricles cannot be directly derived from end-diastolic pressure. Together, these findings show that noeE is a host-specificity gene which probably encodes a fucose-specific sulphotransferase. No distinct advantage to using the transverse colon was observed. A variant gD protein, gD-1(delta290-299t), showed enhanced binding to HVEM(200t) relative to the binding of gD-1(306t). Laparoscopic and open subtotal colectomy for inflammatory bowel disease. Dideoxy fingerprinting (ddF) was used as a tool to search for a generic set of conditions with sufficient power to detect virtually all mutations. Laparoscopic cholecystectomy versus open cholecystectomy in elderly patients with acute cholecystitis: retrospective study. Survival was modelled on the COHERE study extrapolated to a 5-year horizon as a constant hazard.

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Adherence was in an aggregative or stacked-brick pattern, resembling that seen on HEp-2 cells. Peer-reviewed English publications were found through key word searches in MEDLINE, PsycINFO, Scopus, and Embase, and by contacting authors in the field. The application to the allometry of organs reveals other possible scaling for the bronchial tree and the kidney arterial tree of mammals. A five-year Markov model was built form patients with schizophrenia on the stage of maintenance. The Mediterranean area is of interest due to a great diversity and population mixing. Use of vibrational angioplasty for the treatment of chronic total coronary occlusions: preliminary results. NF-kappa B homodimer binding within the HIV-1 initiator region and interactions with TFII-I. About adipocytokines, leptin level decreases after suction-assisted lipectomy while results are contradictory about adiponectin and resistin levels. With the onset of ovulation, breast mitotic activity increases and is usually maximal in the luteal phase.

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Extravillous trophoblast expressed HLA-G and HLA-C in both beta2m-associated form and as free heavy chains. We hypothesize that certain MR imaging characteristics can be used to differentiate between patients with and without 1p and 19q deletion. The total hospitalization cost, check cost (such as laboratory testing and ultrasound), drugs cost, length of stay in hospital and ratio of renal biopsy in all patients were analyzed. The dentinogenic ghost-cell tumor is a rare solid variant of the calcifying odontogenic cyst. Selective expression of mRNA coding for the truncated form of erythropoietin receptor in hematopoietic cells and its decrease in patients with polycythemia vera. Procainamide induces a transitory impairment of B cell mitogenesis in beagle dogs. Changes in methylation status of miRNAs were more indicative of target gene expression and pathological diagnosis than respective miRNA expression changes, suggesting the importance of genome-wide miRNA methylation for tumor development.

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pylori) in which individuals under the age of 50 years would be screened once. In factor analysis, the principal components were rotated after the initial extraction (the authors recommended the use of oblimin rotation) in order to obtain better ground for interpretation of the obtained results. The analysis of a number of segmentation genes suggests that the repressor function of Even-skipped (Eve) may be diminished, causing an indirect loss of Ftz-mediated activation of engrailed. Experimental cerebral venous thrombosis: evaluation using magnetic resonance imaging. The planarian Schmidtea mediterranea maintains and regenerates all its adult tissues through the proliferation and differentiation of a single population of pluripotent adult stem cells (ASCs) called neoblasts. We aimed to analyze the relationship between the ZJU index and IR. Mode-medium instability and its correction with a Gaussian-reflectivity mirror. Three circular sections of the anterior capsule, one lens, and 17 capsules undergoing postoperative healing were studied.

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Monitoring and identification of spatiotemporal landscape changes in multiple remote sensing images by using a stratified conditional Latin hypercube sampling approach and geostatistical simulation. Our recent research is directed toward obtaining a better understanding of the cancer risk of butadiene in humans by evaluating species-dependent differences in the formation of the toxic metabolites epoxybutene and diepoxybutane. A paper-based DNA extraction allowed direct processing of leaf samples already in the field. Discrimination, HIV among People Who Use Drugs, and the UNGASS 2016 on the World Drug Problem. The liquid-based preparations and histopathology were performed in Geneva and the results sent to Cameroon for patient follow-up. Morphologic improvement occurred in 7 of the 22 patients in group A. There is some evidence that medical treatment can cure medially located SPOA.

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Differentially expressed circRNAs were screened using an Arraystar Human CircRNA Array (which includes 13,617 human circRNAs) and qRT-PCR. Ethnographic Investigation of Oral Care in the Intensive Care Unit. At the age of 2 years, during a febrile infection, he developed a hyperkinetic-hypotonic syndrome, which disappeared by fructose-free diet and avoidance of prolonged periods of fasting. The intervention was based on the ORHIS (Oral Health Information Seminars/Sheets) Model and involved computer interaction with six oral health presentations, with no direct oral health professional input. Oral health indicators were collected safely and efficiently from NH residents using a nursing and dental hygiene collaborative approach. The co-translational translocation of proteins into the endoplasmic reticulum (ER) lumen and the biogenesis of membrane proteins require ribosome binding to a membrane channel formed by the Sec61p complex. Nonparenchymal cells from regenerating rat liver generate interleukin-1alpha and -1beta: a mechanism of negative regulation of hepatocyte proliferation.

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The results suggest that ADHD could be heritable via abnormal DAT activities. In this review, we aim to provide a review that could stimulate innovative thought on the progress of a carbon nanotubes sorting method using the aqueous two-phase separation method, and present possible future work and an outlook that could enhance the methodology. Cigar smoking among teenagers--United States, Massachusetts, and New York, 1996. Seasonal variation in the abundance of marine plastic debris in the estuary of a subtropical macro-scale drainage basin in South China. Meiotic drive at the myotonic dystrophy and the cone-rod dystrophy loci on chromosome 19q13.3.

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The authors aimed to analyze the effect of septoplasty, performed in 2 groups with different grades of nasal septal deviation (NSD), on voice performance. It has been ascertained that high-disperse powders of iron obtained by a thermochemical method in the process of formation of particles with pre-determined physical-and-chemical and medical-and-biological properties (essentially monodisperse, harmless, capable of exerting a bactericidal action, having an as-needed specific surface, corrosion resistance, withstanding sterilization heat up to 120 degrees C, allowing the magnetic characteristics to be controlled, etc.) can be used for directed transport of medicinal substances (thyroxin), hormone control, protection of the organism from overdosing of the administered drug preparations. Aspergillus niger-mediated biotransformation of methenolone enanthate, and immunomodulatory activity of its transformed products. Role of the anterior region of the third ventricle in the cardiovascular responses produced by systemic injection of a nitric oxide synthase inhibitor. Choline or methionine, on the other hand, abolished the effects of both alcohol and sucrose supplements. Thus its study will infuse new insight in diseases of both obstetrics and gynaecology. Clinical effects of urokinase and sodium ozagrel in patients with acute symptomatic lacunar infarction.

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We show here that the plasma cell-specific repressor function, designated SIR (suppressor of immune response genes), does not act directly on the transcription of class II genes, but instead on the transcription of the AIR-1 gene, whose product, the class II transactivator (CIITA), is fundamental for the regulation of the constitutive and inducible expression of MHC class II genes. However, this procedure may cause neurological complications caused by cerebrovascular damage. Ten bulk samples, each containing equal amounts of tissue from 52 freshwater invertebrate taxa, were sequenced with the Illumina NextSeq 500 system. Directed calcium chloride coalescence method for preparation of silver nanocubes. Cardiac arrhythmias might explain cases of sudden death in alcoholics during ethanol abstinence. The structure of one class of pre-viral nucleocapsids was determined with single particle reconstruction of cryo-electron microscopy images. Progress in clinical research on left ventricular reverse remodeling in patients with dilated card iomyopathy.

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This paper expands the standard model of utility maximization to endogenize the ubiquitous phenomenon of adaptation. The ideal prodrug achieves delivery of a parent drug by attachment of a non-toxic moiety that is stable during transport and delivery, but is readily cleaved to release the parent drug once at the target. The calculation of the components of the coefficients of variation showed a predominance of the within variance as the cause of the poor reproducibility for the BP measurements, while changes in HR were more influenced by the between variation. To address this challenge, cultures of human neurons on micropatterned surfaces are developed that promote neuronal survival over extended periods of time. Complex hygienic indices for evaluating the risk of soil pollution as a result of using superphosphate and potassium chloride. Respiratory navigation of 3D SPGR sequences is technically feasible, and image quality is modestly improved over free breathing acquisitions using conventional 3D SPGR sequences.

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It is proposed that the UCP-3 gene is predominantly regulated in neonatal muscle by PPAR-alpha activation. There was no important effect of age of onset on clinical features in HMSN type 2 patients. In comparing these parameters with baseline, only SDNN was lower in a positive situation. This study was aimed at validating the leptospirosis surveillance case definition, using the Microscopic Agglutination Test (MAT). Functional characterization of gouC and gouD in gougerotin biosynthesis.

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Medline, Embase, selected databases and websites were searched for documents published between 2010 and 2015. Complete data were evaluated for 272 catheters inserted into 230 patients (141 standard and 131 silver-integrated central venous catheters). Sequences from the rat FN gene directed efficient expression of a lacZ reporter gene product, beta-galactosidase, in NIH/3T3 mouse fibroblasts. In addition, there was considerable variation in success among theolair 250 mg males, although this variability did not depend upon the number of males participating in spawning. Calcium pantothenate modulates gene expression in proliferating human dermal fibroblasts. Anaerobic metabolic changes were studied by assessing N-acetyl aspartate/choline and lactate/N-acetyl aspartate ratios in the symptomatic and asymptomatic hemispheres. Autophagy induction in tobacco leaves infected by potato virus Y(O) and its putative roles.

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Any eventual decision regarding the retention or removal of an ailing implant must also be balanced with the desires of the patient, who typically will have already invested significant time and money to have the implant initially placed and restored. To ensure that maximal antibiotic bioavailability occurs with intermittent depakote medication maximum dosage intraperitoneal (IP) dosing, it is recommended that the antibiotic-containing dialysate must dwell at least 4 hours to ensure an adequate antibiotic depot in the body. Noradrenergic regulation of synaptic plasticity in the hippocampal CA1 region. Some of these peptides inhibited merozoite invasion of RBCs yet did not inhibit intraerthrocytic development. A summary is presented of currently available prognostic factors in advanced ovarian cancer of the common epithelial types.

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The patient tolerated the procedure well and had complete resolution of his exertionally dependent myelopathic symptoms. The study was performed according to an ABAB design, in which A represented the baseline and B represented intervention phases. Repeated exposure also led to a reduction in sensitivity of plasma angiotensin-converting enzyme to the inhibitor. To study disease severity and response to enzyme replacement therapy in Gaucher disease. The volume of urine voided in 4 h by Brattleboro rats was progressively reduced to zero by M320 (10-100 micrograms kg-1 s.c.). Our results provide new inference tools, and suggest that for autosomal population genetic data from diploid or polyploid highly fecund populations who may have skewed offspring distributions, one should not apply Lambda-coalescents, but Xi-coalescents. The second research line, in progress now, develops a virtual environment to improve the learning abilities of children with Attention-Deficit and Hyperactivity Disorder (ADHD). Repeated ECS, but not antidepressant drug administration, markedly enhances dopamine-mediated behaviour. Because new applications for known medications are emerging, focusing on medications rather than syndromes enables the primary care physician to apply known medications to new indications.

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Administration of ACTH to suckling rats results in hyperkinetic behavior. Analysis of acousto-optic interaction based on forward stimulated Brillouin scattering in hybrid phononic-photonic waveguides. After a 30-minute period a calcium concentration-response curve was repeated. Especially the cozaar 100mg tab exposure to toxic fumes was considered a risk because prior research has proven that large amounts of chemical compounds are emitted during the burning of chemical substances such as polyamide. Sales data were used to express results as abuse rate and abuse rate ratio. The benefit in reducing cardiovascular risk with statins has been attributed both to cholesterol lowering and pleiotropic effects.

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Activities of hexulose-phosphate synthase, phosphoribulokinase, and ribulose 1,5-bisphosphate carboxylase were shown in the soluble fraction of gill tissue cells. There is also accumulating evidence that increased omega-3 fatty acid levels in red blood cells are positively related to strength and measures of physical function. The triadic match: the interactive effect of supervisor, candidate, and patient. Late-onset life-threatening angioedema and upper airway obstruction caused by angiotensin-converting enzyme inhibitor: report of a case. Ablation is compared to that from an Er:YAG laser, the current laser of choice for stapedotomy, and is found to be superior. The total number of reflux episodes increases during the postprandial period irrespective of PPI therapy. We report on a 33-year-old female with a microduplication of 15q11-q13 detected by array-CGH analysis, with particular reference to the epilepsy phenotype, characterized as a late-onset Lennox-Gastaut syndrome.

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The main limitations are that the study may not be fully representative of the NI population due to the exclusion criteria applied and also the possible misclassification of conflict related events. However, there are no studies on Dextran-70 pharmacokinetics in cirrhosis. Repression of glutamate dehydrogenase formation in Klebsiella aerogenes requires two binding sites for the nitrogen assimilation control protein, NAC. We critically review the extant clinical trials for these treatments, and discuss both antidepressants efficacy and adverse events, including risk for suicidal events. The diagnosis of streptobacillary rat-bite fever was made after isolation of Gram-negative bacilli from a blood-culture and from cutaneous lesions. Using the process-dissociation procedure, we found that instructions to respond logically and response speed affected analytic (controlled) processing (C), leaving heuristic processing (H) unchanged, whereas the intuitive preference for large nominators (as assessed by responses to equal ratio trials) affected H but not C.

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Skeletal maturation in severe bronchial asthma was studied in 15 children during and after treatment with depot tetracosactrin and in 6 children during treatment with prednisolone. Syndromes once thought to be distinct from FAP are now recognized to be part of the phenotypic spectrum of FAP. In this review, we present the latest advances in the use of PLA nanofibrous scaffolds for musculoskeletal, nervous, cardiovascular, and cutaneous tissue engineering and offer perspectives on their future use. Simulations show that both SIMEX methods perform better than ignoring measurement error. Human solid tumors frequently have albenza drug pronounced heterogeneity of both neoplastic and normal cells on the histological, genetic, and gene expression levels.

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Five subjects with severe to profound unilateral deafness having also ipsilateral tinnitus were enrolled. Data collected via postal questionnaires, including on client-perceived negative responses. Incidental report on use of combined oral therapy with vitamin B12 and folic acid. Use of a Disposable Syringe as a Novel Economic Breath-Collection Chamber for Mice. There is no indication that simultaneous administration of measles vaccine and vitamin A supplements has a negative effect on measles immunity. All animals were alive after the surgery until the end of the experiment (30 days). It is proposed that the pathogenesis of nerve lesions involves an interaction between the specialized nerve vascular system and focal ischemic lesions resulting from rheologically induced stasis. HA-CA hydrogels also retained the angiogenic functionality of hADSCs and supported osteogenic differentiation of hADSCs. Cell growth and the production of extracellular proteases were investigated using a 15-l stirred-tank reactor and 13-l and 1500-l airlift reactors.

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