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Alzam (Alprazolam)

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Alzam is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder. It's also used in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Alzam, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alzam is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Alfix, Alfresh, Alltop, Alpraday, Alpram, Alpraquil, Alprogard, Altrex, Alzam, Alzoact, Alzoax, Alzom, Alzomax, Ambulax, Ambutech, Anxilam, Anxitab, Belfa, Betapax, Dizeral, Emcalm, Erazol, Ezoprax, Fultop, Himzolam, Kurelam, Mcalm, Nexlpra, Nitril, Nokzok, Ozolam, Procalm, Prozolam, Resta, Resto, Restyl, Richpram, Serxanti, Setlan, Suzilam, Tranisol, Trustin, Xerodep, Xylonite, Zeprax, Zolyde, Zopral

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Lioresal, Lipitor, Zithromax, Acticin, Elocon, Anafranil, Kemadrin, Aygestin, Glyburide, Estrace, Kexorm, Lodep, Xalatan, Urpam, Asart, Xibra, Stomorgyl, Enadigal, Denapril,

Also known as: Alprazolam


Alzam XR (alprazolam) is in a group of drugs called benzodiazepines (ben-zoe-dye-AZE-eh-peens). Alprazolam affects chemicals in the brain that may become unbalanced and cause anxiety.

Alzam XR is used to treat anxiety disorders, panic disorders, and anxiety caused by depression.

Alzam XR may also be used for other purposes not listed in this medication guide.


Take Alzam XR exactly as it was prescribed for you. Do not take the medication in larger amounts, or take it for longer than recommended by your doctor. Follow the directions on your prescription label.

Your doctor may occasionally change your dose to make sure you get the best results from this medication.

Alzam XR may be habit-forming and should be used only by the person it was prescribed for. Alzam XR should never be shared with another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it. Do not crush, chew, or break a Alzam extended-release tablet. Swallow the tablet whole. It is specially made to release alprazolam slowly in the body. Breaking the tablet would cause too much alprazolam to be released at one time.

Contact your doctor if this medicine seems to stop working as well in treating your panic or anxiety symptoms.

Your symptoms may return when you stop using Alzam XR after using it over a long period of time. You may also have seizures or withdrawal symptoms when you stop using Alzam XR.

Withdrawal symptoms may include blurred vision, trouble concentrating, loss of appetite, diarrhea, muscle twitching, numbness or tingling, or increased sensations.

Do not stop using Alzam XR suddenly without first talking to your doctor. You may need to use less and less before you stop the medication completely.

To be sure this medication is helping your condition, your doctor will need to check your progress on a regular basis. Do not miss any scheduled visits to your doctor.

Store Alzam XR at room temperature away from moisture, heat, and light. Remove any cotton from the bottle of disintegrating tablets, and keep the bottle tightly closed.

Keep track of how many pills have been used from each new bottle of this medicine. Benzodiazepines are drugs of abuse and you should be aware if any person in the household is using this medicine improperly or without a prescription.

Detailed Alzam XR dosage information


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of alprazolam can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, and fainting.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alzam XR dosage information

Side effects

The most common side effects associated with Alzam are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


You should not take Alzam if:

you also take itraconazole or ketoconazole (antifungal medicines); or you have a history of allergic reaction to any benzodiazepine (alprazolam, diazepam, lorazepam, Ativan, Klonopin, Restoril, Tranxene, Valium, Versed, and others).

To make sure Alzam is safe for you, tell your doctor if you have ever had:

breathing problems such as COPD (chronic obstructive pulmonary disease) or sleep apnea (breathing that stops during sleep); drug or alcohol addiction; depression, mood problems, or suicidal thoughts or behavior; or kidney or liver disease (especially alcoholic liver disease).

Tell your doctor if you are pregnant or plan to become pregnant. Alprazolam may harm an unborn baby. Avoid taking this medicine during the first trimester of pregnancy.

If you use Alzam while you are pregnant, your baby could become dependent on the drug. This can cause life-threatening withdrawal symptoms in the baby after it is born. Babies born dependent on habit-forming medicine may need medical treatment for several weeks.

You should not breastfeed while using alprazolam.

Alzam is not approved for use by anyone younger than 18 years old.

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Although the data fail to support the full nine-factor model, a reduced set of items from the Multifactor Leadership Questionnaire appears to show evidence of the three- and six-factor structures. The production of interleukin 1 (IL1) by peritoneal and splenic macrophages from rats with adjuvant-induced arthritis on day 17 postadjuvant treatment was not altered compared with normal. We analyzed all of therapeutic attitudes suggested and their results. Osteoclast production was undetectable in op/op cell cultures, but was restored by M-CSF at concentrations approximately an order of magnitude higher than those that induced macrophages. We show that bobbed and bobbed-lethal alleles do not magnify in closed X chromosomes, but that a spontaneous ring opening restores normal magnification. Translational GTPases are a family of proteins in which GTPase activity is stimulated by the large ribosomal subunit.

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The effectiveness of antipsychotic medication in the management of behaviour problems in adults with intellectual disabilities. She delivered by cesarean section at 39 weeks a growth restricted female baby weighing 1950g without evidence of congenital malformations. Decisions to breach confidentiality when prisoners report violations of institutional rules. Although they are not part of the ion conduction pathway, the lipid-exposed middle and outer rings significantly modulate nAChR function. This article reviews mechanisms involved in development of hepatocellular carcinoma and how host and environmental factors interact at a molecular level to cause cancer. The model uses topology-weighted transit compartment approach and comprises four main steps which include weighting the edges, simulating signal transduction in the network (weighting the nodes), finding paths between initial and target nodes, and assigning a significance score to each path. A DNA sequence, downstream the ATG codon of nifH, that could be involved in the negative regulation of nifH transcription, was identified. Cohort of children with chronic pain recruited from the open population. This study aims to characterize the pharmacokinetics/pharmacodynamics of drospirenone and estradiol in the treatment of postmenopausal women with moderate to severe vasomotor symptoms and to explore the relationship between the serum exposures of estradiol and drospirenone and efficacy, measured by reductions in moderate to severe hot flushes.

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The prediction error (PE) hypothesized by the temporal difference model has been shown to correlate with the phasic activity of dopamine neurons during reward learning and the blood-oxygen level dependent (BOLD) response during reward and aversive conditioning tasks. Microdiscectomy and anterior cervical fusion with carbon fiber cage containing a core of granulated coralline hydroxyapatite was performed. However, relative selectivity of dysfunctional phagocytosis among diverse respiratory pathogens: NTHI, Moraxella catarrhalis (MC), Streptococcus pneumoniae (SP), and nonbacterial particles, as well as the contribution of impaired phagocytosis to severity of COPD, has not been explored. To choose the correct surgical therapy, sufficient diagnostic is necessary. In the SST, a frequent go signal instructs participants to make a speeded response and a less frequent stop signal instructs them to withhold the response. We hypothesized that a greater number of motion-probing gradients (MPGs) would provide better results of diffusion tensor (DT) fiber tractography of the optic radiation. The decapping scavenger enzyme DCS-1: a new modulator of miRNA turnover. PFGE is often employed to track pathogens, such as Salmonella, Shigella, Escherichia coli (including O157), Campylobacter, and Listeria species through the food chain.

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NBI cystoscopy and bipolar electrosurgery in NMIBC management - An overview of daily practice. This short review discusses exciting potential diagnostic and therapeutic applications of microRNAs to cardiac hypertrophy and HF, highlighting the underlying molecular pathways. Radiolabelling studies were used to assess incorporation of glycerol into parasite phospholipids. The localization of CLIC4 to the cortical actin cytoskeleton and its association with AKAP350 at the centrosome and midbody suggests that CLIC4 may be important for regulating cytoskeletal organization during the cell cycle. It also correlated with 2nd-year OSCE score, clerkship grade in Family Medicine, clerkship ward evaluation in Internal Medicine and final grade in medical school. Recently, tissue engineering has garnered interest as a means to generate cell-seeded three-dimensional scaffolds that could replace diseased organs without requiring immunosuppression. We analysed prospective fertility data of a group of 30 patients with chronic prostatitis NIH IIIB and compared these data with the duration of symptoms as well as with an age-matched control group. The effect of the working conditions on the development of diseases in cast-iron welders. Using amorphous trehalose as a model disaccharide, the simulation unambiguously defines the range of most populated conformations in the glass. Relatively small absolute reductions in non-HDL-C cutpoints result in substantial reclassification of patients to higher treatment categories with potential implications for risk assessment and treatment.

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Mechanical and physical characteristics of the system (biocompatibility, high strength, malleability, possibility of adequate stabilization) are discussed. By means of this in vitro PLA2 inhibitor assay system, two different PLA2 inhibitors were used to compare their inhibitory effects on the hemolymph PLA2 of S. TRB3 is a member of TRB protein family characterized by containing a variant kinase domain without enzymatic activity. We propose compensatory fixation as a mechanism for the in vivo persistence of variants with multiple PI-resistance mutations in the absence of PI therapy. We estimated the cost of production losses due to morbidity (absenteeism and presenteeism) and mortality costs (years of production losses) in the market and nonmarket spheres. Frequency and circumstances of falls in people with inclusion body myositis: a questionnaire survey to explore falls management and physiotherapy provision. Antimicrobial activity of Thai medicinal preparation of Khampramong Temple used for cancer treatment and its plant components. Repetitive transcranial magnetic stimulation (rTMS) and transcranial direct current stimulation (tDCS) are powerful tools to inhibit or facilitate cortical excitability. Increasing the number of acute care transfers by a small amount can significantly bias the SMR, leading to incorrect inference about ICU quality. Although platelet count is a good parameter for the diagnosis of disseminated intravascular coagulation (DIC), a single measurement of platelet is not enough to reflect the ongoing platelet consumption because of compensatory synthesis of circulating platelet number.

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Effects of northeast monsoon on trace metal distribution in the South China Sea off Peninsular Malaysia. Bypass to the left coronary artery system may accelerate left main coronary artery negative remodeling and calcification. At 3-7 days post-induction, some intracardiac neurons showed an overall increase in electron density, with the dendrites darkening first. Here, we report that in conjunction with Mical proteins, methionine-R-sulfoxide reductase B1 (MsrB1) regulates mammalian actin assembly via stereoselective methionine oxidation and reduction in a reversible, site-specific manner. Phosphorylation of each of the four proteins is increased 2-4-fold in response to PMA. At least 70 subjects were examined further at 60 day intervals until September of their second year. Carbon dioxide pneumoperitoneum was used in three patients, but helium pneumoperitoneum was used in the patient with bilateral pheochromocytoma to prevent CO2 retention.

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To determine the impact of a single-session of repetitive transcranial magnetic stimulation (rTMS) and an rTMS intervention on neurophysiology and motor control in survivors of stroke. In addition to SSCP analyses, partial sequencing of the cDNA PCR product containing R462Q mutation site were performed. Eight other patients had complications like CSF leak, meningitis, pseudomeningocele, laryngeal edema, and transient worsening of neurological deficits. Correction factors for central corneal thickness in Goldmann applanation tonometry. Restriction of side-chain conformations in the helix, with a corresponding reduction in conformational entropy, is the likely explanation. Recently, satisfactory anti-bacterial agents and therapeutic alternatives are available. Compared with the previous TCA, the modified TCA method shows a significant improvement in the sensitivity to detect activation peaks of the whole brain. Derivation of glycine from threonine in Escherichia coli K-12 mutants. These relatively low molecular weight proteins are usually grouped into four subfamilies, termed true RAS, RAS-like, RHO, and RAB/YPT, based on the presence of shared amino acid sequence motifs in addition to those involved in guanine nucleotide binding.

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Early developmental responses of mountain birch (Betula pubescens subsp. A crucial aspect for the application of bioelectrochemical systems (BESs) as a wastewater treatment technology is the efficient oxidation of complex substrates by the bioanode, which is reflected in high Coulombic efficiency (CE). We show that for a wide range of physical parameters, this entangled state is formed on how many mg of pepcid can i take a day a time scale given by the strengths of coherent Raman and Rabi fields applied to the atoms, while it is only weakly dependent on the Rydberg interaction strength. Thus, left versus right MTLE was associated with relative deficits in verbal versus nonverbal intelligence, respectively. Although molecular methods are predicted to be widely used in diagnosing and monitoring CNS infections, results generated by these methods need to be carefully interpreted in combination with clinical findings. This work numerically investigates optical responses (absorptance, reflectance, and transmittance) of deep slits with five nanoscale slit profile variations at the transverse magnetic wave incidence by employing the rigorous coupled-wave analysis. The performance of the Finnish Diabetes Risk Score, a modified Finnish Diabetes Risk Score and a simplified Finnish Diabetes Risk Score in community-based cross-sectional screening of undiagnosed type 2 diabetes in the Philippines. A 5-point ordinal Likert scale was used, with higher scores being more favorable. Role of Platelet rich fibrin in wound healing: A critical review. In conventional strip biosensor, methylated histone is captured on the test zone through the formation of antibody/methylated histone/antibody-labeled AuNP sandwich structures.

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