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Alprocalm (Alprazolam)
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Alprocalm

Alprocalm is a potent, short-acting benzodiazepine anxiolytic—a minor tranquilizer. It is commonly used for the treatment of anxiety disorders, especially of panic disorder. It's also used in the treatment of generalized anxiety disorder (GAD) or social anxiety disorder. It was the 12th most prescribed medicine in the United States in 2010. Alprocalm, like other benzodiazepines, binds to specific sites on the GABAA receptor. It possesses anxiolytic, sedative, hypnotic, skeletal muscle relaxant, anticonvulsant, amnestic, and antidepressant properties. Alprocalm is available for oral administration as compressed tablets (CT) and extended-release capsules (XR).

Other names for this medication:
Aderta, Alamflu, Almac, Alparazole, Alpra, Alpramax, Alprax, Alprine, Alprotame, Alrif, Alzac, Alzocum, Alzomax, Alzopam, Alzotime, Anxiflu, Besquil, Cooltime, Deproz, Elflu, Fluprax, Fluti, Fultop, Isorest, Manzolam, Pecalm, Pranol, Restyl, Rezolam, Rivcam, Setlan, Tenfree, Tensyl, Tranax, Tranisol, Unixl, Zallpam, Zenax, Zolin, Zolorel, Zorest

Similar Products:
Feldene, Periactin, Fasigyn, Prometrium, Floxin, Diflucan, Clomid, Srivasmine, Mizap, Primodil, Conpres, Durize, Ariclaim,

Also known as: Alprazolam

Description

Alprazolam is used to relieve symptoms of anxiety, including anxiety caused by depression. It is also used to treat panic disorder in some patients.

Alprazolam is a benzodiazepine. Benzodiazepines belong to the group of medicines called central nervous system (CNS) depressants, which are medicines that slow down the nervous system.

This medicine is available only with your doctor's prescription.

Dosage

This section provides information on the proper use of a number of products that contain alprazolam. It may not be specific to Alprocalm. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is used for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Swallow the extended-release tablet or tablet whole with a full glass of water. Do not break, crush, or chew it.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not remove the tablets from the bottle until you are ready to take it. Place the tablet immediately on the top of your tongue. It should melt quickly and be swallowed with saliva.

If you are using the oral liquid, measure the dose with a marked measuring spoon, oral syringe, or medicine cup.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For anxiety: For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.25 to 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 4 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For panic disorder: For oral dosage form (extended-release tablets): Adults—At first, 0.5 to 1 milligram (mg) taken in the morning once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.5 mg taken in the morning once a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of alprazolam can be fatal.

Overdose symptoms may include extreme drowsiness, confusion, muscle weakness, loss of balance or coordination, feeling light-headed, and fainting.

Storage

Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company for more details.

Side effects

The most common side effects associated with Alprocalm are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Avoid drinking alcohol. Dangerous side effects or death could occur.

Avoid driving or hazardous activity until you know how this medicine will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries.

Grapefruit may interact with alprazolam and lead to unwanted side effects. Avoid the use of grapefruit products.

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Described herein is a novel, electrical discharge-based reagent ion source that is located in the first differentially pumped region of the mass spectrometer. In this study, we examined the relationships between self-reported sleep disturbance symptoms and health-related quality of life measures in the Fels Longitudinal Study. Topographical thickness of the epithelium and total cornea after overnight wear of reverse-geometry rigid contact lenses for myopia reduction. Surface oxidation and metal contamination were assessed by X-ray photoelectron spectroscopy. This Review presents our epidemiological findings, based primarily on the ARIC Study, in the context of the other epidemiological studies supporting the inflammatory nature of diabetes, CVD and the metabolic syndrome. Patterns of injury and outcomes associated with motocross accidents. Action tremor and ataxia associated with a history suggestive of premature ovarian failure should raise suspicions for FXTAS.

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Based on social cognitive theory, the purpose of this study was to determine whether selected environmental and behavioral factors were associated with the calcium intake of low-income adolescent girls. Meningoencephalitis associated with polyradiculoneuropathy with increased HSV IgG antibody--report of three cases. These effects of long duration pulses on recovery of excitability in a fixed population of neurons may have contributed to the delay in recovery implied by the psychophysical data. Reference values for fetal tissue velocity imaging and a new approach to evaluate fetal myocardial function. In this study, high vancomycin trough levels were identified as an independent factor associated with risk of nephrotoxicity in MRSA-infected patients. Elevated free glucose per se may have a role in diabetic cataractogenesis in addition to the metabolism of glucose to sorbitol and osmotic changes to the lens. As it is significantly less prone to minor complications we recommend the use of balloon-retained gastrostomy tubes to improve the practicability and maintenance of RIG. However, only the largest family (the Corvidae) had significantly heightened rates of both speciation and regional transition, implying that repeated regional colonization is not a general mechanism promoting lineage diversification among the Corvides.

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The effects of taurine on perfused heart muscle malondialdehyde levels. TD is common in children aged 6-12 years and more prevalent in boys than in girls. This suggests that shorter estrogen exposure from prepuberty to PBM is not the main factor for increased osteoporosis risk associated with later menarche. Glioblastoma U251 and U87 cells irradiated with single fraction high dose rate radiation (1.1 Gy/min) were relatively insensitive to inactivation of colony forming ability, similar to other glioblastoma cell lines. Mercury or silver was electrodeposited on an Au surface to form an Hg-Au or Ag-Au film. In the second example, we address the estimation of the two dynamic variables and the phase parameter of a numerical model commonly employed to represent the dynamics of optoelectronic feedback loops designed for chaotic communications over fiber-optic links. This is an important question as usually identifiability is assumed, and parameters are sought without first establishing whether these can be inferred from a set of measurements. We sought additional information from trial authors as required. In this article, we propose a practical model to guide alcohol policy implementation.

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An aneurysm of the interatrial septum and cerebral embolic events: a clinical case and review of the literature. In contrast, it has a very robust disulfide-bond reductase activity toward 2-hydroxyethyldisulfide on par with mammalian and bacterial glutaredoxins. With patience and careful evaluation,,the correct place for the procedure will be found and, though it is not quite the panacea once claimed for patients with coronary artery disease, aortocoronary bypass surgery will remain an important and valuable therapeutic tool, perhaps the most significant development in cardiovascular treatment of the past decade. A frequency determination of the T cell precursors in murine adult and fetal thymuses as well as in the bone marrow and fetal liver was made. While it is known that the application of gamma-aminobutyric acid-A (GABA(A)) agonists and antagonists affects the performance of classically conditioned eyeblinks, the effects of these drugs on IN neurons in vivo are not known.

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Screw migration, which is the distance from the screw tip to the anterior cortex and the upper endplate of the vertebra, was also evaluated immediately after surgery and at the mean follow-up of 15.9 months. We prospectively assessed the kinetics of the antiangiogenic factor soluble Fms-like tyrosine kinase-1 (sFlt-1) in 136 consecutive RT patients and analyzed sFlt-1 impact on DGF and PTC loss. Patients should be advised about the effects of PHD testing without anesthesia on their psychological well-being in the long run. Shoulder pain is common in how to pronounce generic zetia acute tetraplegia and is associated with loss of shoulder ROM. We used confocal microscopy to demonstrate aureolysin (Aur), Hla, SspA and SspB are produced following phagocytosis by human neutrophils, thereby linking exoprotein production in vitro with that during host-pathogen interaction. Attenuations are obtained computationally as a function of side deformation for different design parameters.

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Extremely preterm infants undergoing high-frequency oscillatory ventilation have remarkably low cerebral blood flow in the first 12 h of life, median 6.7 (range 4.4-11) mls. Urinary endothelin excretion in the neonate: influence of maturity and perinatal pathology. Functional recovery of elbow flexion was measured using the MRC grading system which showed 1 M5/5, 5 M4, 4 M3, and 3 M2 outcomes. A significant positive correlation was found between HLA-DR and cytoplasmic IL-6 expression, between HLA-DR and cytoplasmic IL-8 as well as between IL-6 and IL-8 cytoplasmic expressions. These findings will aid our understanding of paramyxovirus particle assembly in general and could help facilitate the development of a novel vaccine approach for henipaviruses.

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NeP1 is neutral on a monomeric binding site, but mediates weak repression on a multimerized site and strong synergistic repression in conjunction with v-ERBA on the wild-type silencer. In vitro carcinogenesis of mammary epithelial cells by N-nitroso-N-methylurea using a collagen gel matrix culture. Overexpression of wild-type NF-E2 related factor-2 (Nrf2) dramatically increased ARE-reporter gene expression in a dose-dependent manner. Rapid measurement of urinary IL-6 by ELISA: urinary IL-6 as a marker of mesangial proliferation. An increase of 1 h per week of leisure-time physical activity was associated with a 0.17- and 0.39-point increase in the vitality dimension in men and women, respectively. We show that the plasma frequency of the radial superlattice can be tuned over a broad range in the visible and near infrared by changing the layer thickness ratio in good agreement with an effective metamaterial description. Evidence for distinct subcellular localizations of electrogenic and ATP-dependent taurocholate transport in rat hepatocytes.

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Callosal dysfunction explains injury sequelae in a computational network model of axonal injury. Tendinous insertions in the human thyroid cartilage plate: macroscopic and histologic studies. Patients were more satisfied with iontophoresis at session 2 when they took over control, but lost enthusiasm by session 3. Intrahepatic plastic stent entrapment due to guide wire stripping. To date, most applied research evaluating the clinical utility of multiple schedules has done so in the context of behavior maintained by positive reinforcement (e.g., attention or tangible items). The solids can be additionally functionalised in the external surface with gate-like systems that can be opened on command to allow cargo release. A case is reported and four cases reported during the past 20 years are reviewed. This work further supports the hypothesis that Cr contamination of surface waters could contribute to explain the reported worldwide depletion of frog population. For a given acquisition time, selective averaging results in a signal-to-noise ratio penalty compared to averaging all lines equally.

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