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Alprazolam is commonly used to treat anxiety and panic disorders. It falls into a category of medications called benzodiazepines. They are known to affect the central nervous system components and produce a calming effect, thus decreasing brain activity.

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Alprazolam is a benzodiazepine (ben-zoe-dye-AZE-eh-peen). Alprazolam affects chemicals in the brain that may be unbalanced in people with anxiety. Alprazolam is used to treat anxiety disorders, panic disorders, and anxiety caused by depression.

You should not use Alprazolam if you have narrow-angle glaucoma, if you also take itraconazole or ketoconazole, or if you are allergic to Alprazolam or similar medicines (Valium, Ativan, Tranxene, and others).

Alprazolam may be habit-forming. Misuse of habit-forming medicine can cause addiction, overdose, or death.

Do not drink alcohol while taking Alprazolam. This medication can increase the effects of alcohol. Alprazolam may be habit-forming and should be used only by the person for whom it was prescribed. Keep the medication in a secure place where others cannot get to it.


This section provides information on the proper use of a number of products that contain alprazolam. It may not be specific to Alprazolam XR. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. If too much of this medicine is used for a long time, it may become habit-forming (causing mental or physical dependence) or cause an overdose.

This medicine should come with a Medication Guide. Read and follow the instructions carefully. Ask your doctor if you have any questions.

Swallow the extended-release tablet or tablet whole with a full glass of water. Do not break, crush, or chew it.

If you are using the orally disintegrating tablet, make sure your hands are dry before you handle the tablet. Do not remove the tablets from the bottle until you are ready to take it. Place the tablet immediately on the top of your tongue. It should melt quickly and be swallowed with saliva.

If you are using the oral liquid, measure the dose with a marked measuring spoon, oral syringe, or medicine cup.

Do not eat grapefruit or drink grapefruit juice while you are using this medicine.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For anxiety: For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.25 to 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 4 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For panic disorder: For oral dosage form (extended-release tablets): Adults—At first, 0.5 to 1 milligram (mg) taken in the morning once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.5 mg taken in the morning once a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage forms (solution, tablets, or orally disintegrating tablets): Adults—At first, 0.5 milligram (mg) 3 times a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 10 mg per day. Older adults—At first, 0.25 mg 2 or 3 times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor.


If you have been prescribed Alprazolam for medical reasons, the best way to avoid a Alprazolam overdose is to adhere to prescribed orders—closely monitor your dose and the time at which you take your medication. Track your Alprazolam consumption in a notebook or on your phone. If you notice that you are taking a higher dose of the drug, taking the drug more often, or you want to consume more of the drug, talk with your doctor immediately.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

It is very important to protect the orally disintegrating tablets from moisture. Remove and throw away any cotton packaging from the medicine bottle when you first use the medicine.

Detailed Alprazolam XR dosage information

Side effects

The most common side effects associated with Alprazolam are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Before taking Alprazolam, tell your doctor or pharmacist if you are allergic to it; or to other benzodiazepines (such as diazepam, lorazepam); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.Before using this medication, tell your doctor or pharmacist your medical history, especially of: severe lung/breathing problems (such as COPD, sleep apnea), liver disease, kidney disease, drug or alcohol abuse, glaucoma.This drug may make you dizzy or drowsy. Do not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Avoid alcoholic beverages.Before having surgery, tell your doctor or dentist about all the products you use (including prescription drugs, nonprescription drugs, and herbal products).Older adults may be more sensitive to the side effects of this drug, especially loss of coordination and drowsiness. These side effects can increase the risk of falling Alprazolam is not recommended for use during pregnancy due to the potential for harm to an unborn baby. Consult your doctor for more details.This drug passes into breast milk and may have undesirable effects on a nursing infant. Therefore, breast-feeding while using this drug is not recommended. Consult your doctor before breast-feeding.

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When viewed in the context of earlier research, our findings suggest that obesity, diabetes, use of hand-held vibratory tools, and repeated forceful movements of the wrist and hand are causes of impaired median nerve function. Among the most important ones are: de novo synthesis of antibodies against HLA class I and II, immunoglobin deposits on vascular endothelial and tubular basement membrane, C4d complement deposits in peritubular capillaries, increased proliferation of lymphocytes in response to mismatched HLA-DR, and elevated expression of cytokines on infiltrating mononuclears and tubular cells. Their great potential in materials applications is demonstrated by the fabrication of organic-inorganic nanocomposites that can be selectively photopolymerized to inscribe extremely effective and volume holographic gratings with the highest refractive index contrast (n(1) of up to 0.024) achieved so far. Rehabilitative therapies in cerebral palsy: the good, the not as good, and the possible. Potential use of vaccines in the primary prevention of breast cancer in high-risk patients.

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Members of peer review committees should not be in a position to benefit from the decision. Chinese herbal formula Qilong-Lishui granule improves puromycin aminonucleoside-induced renal injury through regulation of bone morphogenetic proteins. Influenza Pandemics and Tuberculosis Mortality in 1889 and 1918: Analysis of Historical Data from Switzerland. There was a significant correlation between GIPC/GluN2B and PSD-95/GluN2B ratios, but PSD-95/GluN2B and GluN2A/GluN2B ratios did not show a relationship. Robust variance-components approach for assessing genetic linkage in pedigrees. To develop a theory for this transition, we combine classical percolation theory with the properties of the supercritical nonequilibrium system on a finite-size cluster. The overall objective was to change the functional relationship of the anterior teeth to allow predictable restoration that would decrease the risk of further attrition while satisfying the esthetic expectations of the patient. Secondary hyperparathyroidism and osteomalacia had developed due to severe vitamin D deficiency, occurring as a result of previously unrecognized, minimally symptomatic pancreatic exocrine insufficiency.

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Synthesis and properties of polynucleotide analogs based on N1-(1,4-dioxybutyl-2)-thymine. Two testers performed three separate blinded measurements on each edematous hand, using the figure-of-eight technique. Interactions of core-shell quantum dots with metal resistant bacterium Cupriavidus metallidurans: consequences for Cu and Pb removal. After observing that expression of two NR4A orphan nuclear receptors, NR4A3 and NR4A1, was altered by insulin in cDNA microarray analyses of human skeletal muscle, we studied whether these receptors could modulate insulin sensitivity. Percutaneous renal biopsy was performed in a 40-year old transplant recipient suffering from renal function impairment. This can be blocked by dominant negative Notch1, Notch2, and two Deltex1 mutants lacking the RING-H2 finger motif, but not by dominant-negative RBP-J or Hes1 antisense oligonucleotides. This paper reviews the results from three trials of ZD9331, a novel, direct-acting antifolate, in patients with relapsed or refractory solid tumours.

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Effect of temperature and humidity on the adhesive strength of orthodontic direct bonding materials. With the participation of 46 prostituted women in Korea, this study investigates the relationship between prostitution experiences, a history of childhood sexual abuse (CSA), and symptoms of posttraumatic stress disorder (PTSD) and disorders of extreme stress not otherwise specified (DESNOS). So, it is possible for 1,25(OH)2D3 to promote the differentiation of the cells in megakaryocytic lineage in vivo and to be used to treat acute megakaryoblastic leukemia and other diseases with malignant megakaryocytosis. Frailty was not found to be independently associated with abnormal vision. In addition, increased knowledge of the visual system has opened the door for new techniques such as transcranial magnetic stimulation (TMS) to explore these deficits physiologically.

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Nine of them were excluded because data on their pain treatments were missing, resulting in 125 for analysis. Growth mixture modeling was used to identify estrace pill and estradiol smoking patterns and to assess the effects of the two SNPs and ADHD symptoms on cigarette use over time. p130Cas-associated BCAR3 protein was detected in the estrogen-independent breast cancer cell line 578-T, but not in estrogen-dependent MCF7 or ZR-75-1 cells. Emerging clinical data indicate that the treatment of metabolic acidosis, which is simple and cost-efficient, offers great therapeutic potential. These results demonstrate that the engineered bacterial cell with periplasmic ngCA can successfully serve as an efficient biocatalyst for CO2 sequestration. We tested this hypothesis in a contemporary cohort from 3 centers.

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The mutated genes controlling the synthesis of ionic membrane channels cause disorders in the repolarization phase of action potential. The main immunogenic region (MIR) on muscle AChRs accounts for many aspects of the pathological mechanisms by which the autoimmune response impairs neuromuscular transmission. Sequencing of additional S12 clones retrieved from a shotgun genomic library allowed definition of three subfamilies of this repeat based on minor differences in their nucleotide sequences. While pantoprazole protonix ec tablet 40 mg financial barriers are an important obstacle to equitable access to ARTs, socioeconomic differences in utilization are likely to persist in countries with supportive public funding, due in part to differences in childbearing patterns and treatment seeking behaviour. For a class of practical data arising from observing spatial signals including images, it is desirable for a model to consider general observations, e.g., handling a vector field and non-exchangeable factors, e.g., handling spatial connections between the columns and the rows of the data. British Heart Foundation reflections on research competition 2016. In spite of this, the secondary structure of thesaurin a, deduced from hydrophobic cluster analysis, is remarkably similar to that of EF-1 alpha and EF-Tu.

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Suspected malingering and the Digit Memory Test: a replication and extension. In addition, GHS-R1a knockdown in VMH and DMH reduced body temperature and running wheel activity (RWA). I examine four different kinds of learning conversation: reflective practice, clinical supervision, work consultancy and performance appraisal. There are no available data on the safety of recommended schedules for the initiation of treatment with budesonide inhalation suspension in children with recurrent wheezing episodes. Epigenetics and bipolar disorder: new opportunities and challenges.

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Integrating pharmacies into public health program planning for pandemic influenza vaccine response. Primary ciliary dyskinesia (PCD) is a rare, mostly autosomal-recessive disorder of motile cilia, characterized by chronic lung disease, rhinosinusitis, hearing impairment, and subfertility. The low-temperature crystal structure of the pure-spermine form of Z-DNA reveals binding of a spermine molecule in the minor groove. APD in the medium inhibited resorption and reduced the volume, area, and depth resorbed per nucleus per chick osteoclast. The nutritional requirements of methicillin-dependent and -resistant strains of Pediococcus cerevisiae. A review and update on melanocyte stimulating hormone therapy: afamelanotide. To explore the relationships between verbal aggression, physical aggression and inappropriate sexual behaviour following acquired brain injury. Controlled release formulation has many challenges to overcome, specific to this kind of medicament for inhalation.

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Reverse-transcription polymerase chain reaction analysis for relative expression of AT1 and AT2 receptor mRNA in women with no ovarian factor (NOF), poor ovarian reserve (PR), endometriosis (ENDO), and polycystic ovary syndrome (PCOS). However, for birds, which were adapted for aerial flight, fossil evidence has been less forthcoming to explain the transition to aquatic capabilities. In barley, more than 30 types of dwarfs or semi-dwarfs have been hitherto described. Using 4 waves of a survey of the elderly, we examine the relationship between social ties and perceived support and four health outcomes--mortality, functional status, self-assessed health, and depression. Spatially multiplexed X-Y lateral shear interferometer with varying shears using holographic lens and spatial Fourier transform. Angiotensin receptor blockers are associated with reduced fibrosis and interleukin-6 expression in calcific aortic valve disease. Results indicate significant posttest improvements in depression knowledge, self-efficacy to identify the need for treatment, and decreased stigma in experimental as compared to control group participants.

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