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Aldezole (Metronidazole)

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Aldezole is in a class of drugs called nitroimidazole antimicrobials. This medicine will only help infections caused by bacteria and will not work for the common cold, flu, or other viral infections. It works by stopping the growth of bacteria.

Other names for this medication:
Acuzole, Anaerobex, Arilin, Avidal, Biatron, Cresac, Dirozyl, Elyzol, Emedal, Entizol, Flagolin, Fortagyl, Geloderm, Gnostol, Imizine, Metrocev, Metrofusin, Metrolotion, Metrolyl, Metronidazol, Metronide, Metrosa, Metrosept, Monizole, Nidagel, Nidazyl, Novazole, Patryl, Rovamet, Stomorgyl, Torgyl

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Also known as: Metronidazole


Metronidazole is used to treat bacterial infections in different areas of the body. The extended-release tablets are used to treat women with vaginal infections (bacterial vaginosis).

Metronidazole belongs to the class of medicines known as antibiotics. It works by killing bacteria or preventing their growth. However, this medicine will not work for colds, flu, or other virus infections.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain metronidazole. It may not be specific to Aldezole ER. Please read with care.

Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered.

The capsules can be taken with or without food. If the medicine upsets your stomach, it is best to take it with a meal or snack.

The extended–release tablet must be taken without food, 1 hour before or 2 hours after a meal.

Swallow the extended-release tablet whole. Do not break, crush, or chew it.

To help clear up your infection completely, keep using this medicine for the full time of treatment, even if you begin to feel better after a few days. If you stop using this medicine too soon, your infection may return.

This medicine works best when there is a constant amount in the blood. To help keep the amount constant, do not miss any doses. Also, it is best to take the doses at evenly spaced times during the day. If you need help planning the best times to take your medicine, check with your doctor.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For oral dosage forms (capsules or tablets): For amebiasis infections: Adults—500 or 750 milligrams (mg) 3 times a day for 5 to 10 days. Children—Dose is based on body weight and must be determined by your doctor. The dose is usually 35 to 50 milligrams (mg) per kilogram (kg) of body weight per day, divided into 3 doses, for 10 days. For bacterial infections: Adults—Dose is based on body weight and must be determined by your doctor. The dose is usually 7.5 milligrams (mg) per kilogram (kg) of body weight every 6 hours for 7 to 10 days. Your doctor may increase your dose as needed. However, the dose is usually not more than 4000 mg per day. Children—Use and dose must be determined by your doctor. For trichomoniasis infections: Adults—The tablet can be given 3 different ways: as a single dose of 2 grams, as 1 gram 2 times a day for 1 day, or as 250 milligrams (mg) 3 times a day for 7 days. The capsule dose is 375 mg 2 times a day for 7 days. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): For bacterial vaginosis: Adults—750 milligrams (mg) once a day for 7 days. Children—Use and dose must be determined by your doctor.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include nausea, vomiting, and loss of balance or coordination.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Metronidazole topical dosage information

Side effects

The most common side effects associated with Aldezole are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


There are no adequate studies in women for determining infant risk when using this medication during breastfeeding. Weigh the potential benefits against the potential risks before taking this medication while breastfeeding.

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Delayed clearance of intraabdominal abscesses caused by Candida albicans in tumor necrosis factor-alpha- and lymphotoxin-alpha-deficient mice. The influence of a high-fibre diet on body weight, serum lipids and blood pressure in slightly overweight persons. Association between posterior teeth occlusion and functional dependence among older adults in nursing homes in Japan. The orbitofrontal cortex and basolateral amygdala are two regions which are crucial to this process. Morphine should only be used in selected cases until the advantage of spinal opioid analgesia to control postoperative and cancer pain has been clearly defined in well-designed clinical studies. Bacteriological examination of surgical specimens of pulmonary tuberculosis. Transforming growth factor-alpha-activated kinase 1 (TAK1) has been widely recognized as a kinase that regulates multiple intracellular signaling pathways evoked by cytokines and immune receptor activation. A more biopsychosocial approach to management of these conditions is essential. Physicians should provide patients with comprehensive information about medication features, including toxicities and efficacy (and their potential correlation), to improve compliance and optimize outcomes. When creatively interrogated, a diverse range of large, real-world data sets provides powerful diagnostic tools for revealing principles of human judgment, perception, categorization, decision-making, language use, inference, problem solving, and representation.

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Beer consumption was associated with a significant increase in the underage fatal CIR. The purpose of this study is to describe the demographic and HIV-specific variables associated with ED utilization by HIV-positive adults and their diagnoses when discharged from the ED or subsequently from the hospital. While in vivo BDNF localization was restricted to small neurons, practically all neurons in DRG cell culture displayed BDNF-LI. Although effective against bacterial isolates in vitro, chlorine dioxide solution failed to adequately control these organisms in vivo. The elevation of cAMP was used in combination with the transplantation of a type of peripheral nerve cells, called Schwann cells. Subjective symptoms and abnormal findings on chest X-ray considered directly related to TDI exposure were not observed. Other groups have shown that cells maintained in culture may undergo alterations as they are propagated, and that these alterations may alter the predicted behavior of stem cells. Summation effects in human learning: evidence from patterning discriminations in goal-tracking. Location of mesoporphyrin in liposomes determined by site-selective fluorescence spectroscopy.

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We report a patient with symptomatic sinus node disease on single-chamber atrial pacing for the past 7 years who developed a progressive increase in the PR interval and ultimately presented with symptomatic high-degree atrioventricular block requiring pacemaker upgradation. Immediately following viral entry is reverse transcription, integration, gene expression, encapsidation, budding and lastly virus maturation. Intraoperative CFD is an effective test for detecting flow abnormalities or intimal defects in patients undergoing CEA. Previously, trichostatin A (TSA), a histone deacetylase inhibitor, has been shown to exhibit strong antifibrotic characteristics in hepatic stellate cells (HSC), which are known to play a central role in chronic liver diseases. The outcome measures reported in this paper are the impact of the intervention on two secondary endpoints: oral health promotion activities in the community and personal oral health practice of children. Cardiac troponin-I serum levels after open heart surgery in children and infants 4 h after admission to the ICU allowed anticipation of the postoperative course and correlated with the incidence of significant postoperative complications. From these interviews, a theoretical model of the homeopathic consultation will be developed.

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The EDNR phylogeny supports the recognition of the EDNRA, EDNRB, and EDNRC subfamilies, as well as more lineage-specific duplicates of teleosts and the African clawed frog. WE EXAMINED THE ASSOCIATION between sociocultural status (assimilation, modernization, and socioeconomic status) and blood pressure among people of Mexican origin living in San Antonio, Texas, and Mexico City. We developed a novel design of activity localization fluorescence (ALF) peptide probe, which enables spatially resolved, highly sensitive imaging of peptidase in live cells. Fertilization of C57BL/6 mouse sperm collected from cauda epididymides after preservation or transportation at 4 degrees C using laser-microdissected oocytes. The majority (75 per cent) of pigs with proliferative enteropathy at necropsy were antibody positive and a small number (4 per cent) of pigs in which lesions were not observed were found to have antibody.

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Some microbial strains possess genetic determinants conferring resistance to arsenic derivatives. Each vial contained 0.5 g of sodium sulbactam and 1 g of sodium ampicillin. In such a circumstance, how to select health care workers to whom chemoprophylaxis with isoniazid should be administered was also discussed. We also find that the S1 nuclease cleavage at this site can be dramatically enhanced by the binding of small RNA molecules. Thus, it appears that silica, at least in vitro, is harmful to neutrophils as well as to macrophages. Hence, neuronal membranes are uniquely vulnerable to radical-mediated damage. Characterization of mouse ALCAM (CD166): the CD6-binding domain is conserved in different homologs and mediates cross-species binding.

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In this paper, a nano-pillar array integrated near quantum dots (QDs), which serves as a Purcell cavity as well as a column antenna, is studied in order to enhance the spontaneous emission (SE) rate of low emission efficiency QDs. Sealants placed in first permanent molars in six, seven and eight-year-olds required more retreatment than those in older children. We review the broader challenges of quantitative hepatic vascular MRI, including the difficulties of motion artefact, complex post-processing, long acquisition times, validation and limitations of pharmacokinetic models, alongside the potential solutions that will shape the future of MRI and deliver this new frontier to the patient bedside. Recommended calcium intakes are important for skeletal health and do not appear to increase the risk for iron deficiency in healthy people. Step brightness changes of distant mountain ridges and their perception. Cutting edge: a novel viral TNF receptor superfamily member in virulent strains of human cytomegalovirus. Surprisingly, removal of the H4 N terminus also derepresses the silent mating type loci, HML alpha and HMRa, disrupting mating. However, the empirical confirmation of the specificity of affective dysregulation for BPD is still pending. Inhibition of Growth and Metastasis of Tumor in Nude Mice after Intraperitoneal Injection of Bevacizumab. To present the current understanding of the mechanisms of spinal cord stimulation in relation to the physiology of pain.

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These results suggest a potential role of GSH in combination with other antivirals in the treatment of virus-related diseases. The promoter region contained cAMP response element (CRE) sequences, and the TBM gene transcription was enhanced when cAMP analogs were added to transfected cells. Prior investigations have suggested a clear relationship between nosocomial pneumonia and intramucosal gastric pH (pHi), a probable marker of bacterial translocation. Separation distress in infant rhesus monkeys: effects of diazepam and Ro 15-1788. Mutation of the only known HH receptor gene, Patched (PTC), has recently been implicated in inherited and sporadic forms of the most common human cancer, basal cell carcinoma (BCC). Vision loss in nonneovascular ARMD is highly correlated with the loss of RPE cells and areas of geographic atrophy (GA). These realizations are presented and discussed in terms of the most important parameters of membrane separation especially water flux and retention in this article. 44 patients consecutively admitted to the Pediatric ICU over a period of 3 years who were given nutrition and metabolic support for at least 72 hours. Blue native electrophoresis to study mitochondrial complex I in C. The antibodies differ in their sites of interaction with hemagglutinin and in their abilities to interfere in vitro with its two functions of receptor binding and membrane fusion.

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In some cases (Lys-128 to Gln, Asn, and His), the apparently cytoplasmic variants were able to support limited plasmid DNA replication, suggesting that low levels of large-T antigen undetectable by immunofluorescence were present in the nucleus. Local immunoreactivity and human papillomavirus (HPV) in oral precancer and cancer lesions. To develop a powerful how much does bystolic cost a month archetype editing framework capable of handling multiple reference models and oriented towards the semantic description and standardization of legacy data. Molecular modeling of the interaction of anthracenyl-amino acid topoisomerase inhibitors with the DNA sequence d(CGTACG). Rats with bilateral amygdala cannulae were trained to run a straight alley for a large or small food reward. The cytoplasm-to-vacuole targeting pathway is a variant of selective autophagy in Saccharomyces cerevisiae during which hydrolases such as prApe1 are transported into the vacuole.

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This was the case both for activity related to the preparation phase and also for that elicited during the execution phase. Effect of food intake on blood lead concentration in workers occupationally exposed to lead. Ectopic activation of the TAL-1 gene in T lymphocytes occurs in the majority of cases of human T cell acute lymphoblastic leukemia (T-ALL), yet experiments to date have failed to demonstrate a direct transforming capability for tal-1. First is sexual identity cardizem drip dosage formation which encompasses development of lesbian sexuality and awareness of being a lesbian. The myoendothelial gap junctions were evaluated by using a multi-photon microscope. The aim of the study was to assess some aspects of T lymphocyte apoptosis in MM to obtain a better understanding of the changes in the immune system in this disease. We report that treatment of mouse embryonic stem cells with inhibitors of phosphoinositide 3-kinase, an essential intracellular signaling regulator, produced cells that resembled pancreatic beta cells in several ways.

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Hepatitis B (HBV), hepatitis C (HCV), and HIV blood-borne viruses (BBV) are associated with chronic ill health and mortality. Phylogenetic analysis using three mitochondrial and eight elavil 10 mg tab nuclear genes shows that the low-elevation forms and the proximate, high-elevation species C. Human olfactory neuroepithelial cells: tyrosine phosphorylation and process extension are increased by the combination of IL-1beta, IL-6, NGF, and bFGF. Therefore, NAFLD is usually associated with cardiovascular disease, chronic kidney disease, type 2 diabetes, obesity, and dyslipidemia. Orthodontic tooth movement differs significantly from the physiological tooth movement, because it effects a biological response of the surrounding tissues of the teeth, resulting in a remodeling of the periodontal ligament and the alveolar bone. For this purpose, an antenna-type modified protraction headgear was tested with double exposure holographic interferometry on a dry human skull with well-aligned upper teeth.

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Using images of where can i buy zyrtec 5 mg uncircumcised penises residents were asked to identify which patients were candidates for routine neonatal circumcision. Prion diseases have different etiological background with distinct pathogenesis and phenotype. It was developed according to current standards, and it provides reliable and internationally comparable speech intelligibility measurements. The nucleotide sequence of a 1408 base-pair DNA fragment encoding the insecticidal 27,340 Mr delta-endotoxin of Bacillus thuringiensis var. Novae are thermonuclear explosions on a white dwarf surface fueled by mass accreted from a companion star. Antioxidants phenyl-N-test-butylnitrone, superoxide dismutase, and catalase significantly inhibited KCN-induced COX-2 up-regulation and subsequent apoptosis. The fact makes the coefficients of the linear models constructed by the spectra measured on different instruments are similar in profile. The primary structures of rat ribosomal proteins S3a (the V-Fos transformation effector) and of S3b.

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Two alternative, empirically supported four-factor models of PTSD were compared with the DSM-IV three-factor PTSD diagnostic model. These data show that specific alterations in the TCR repertoire are present in the blood and liver of patients with PBC. Hypoxia-inducible factor 1alpha determines gastric cancer chemosensitivity via modulation of p53 and NF-kappaB. The effects of epidural injection on intracranial pressure (ICP), lumbar epidural pressure, cerebral blood flow (CBF), and spinal cord blood flow (SCBF) were studied after acutely increased ICP in swine. To study the characteristics of peptic ulcer and erosion in pediatric patients. Acid-sensing ion channel-1 (ASIC-1) is a proton-gated ion channel implicated in nociception and neuronal death during ischemia. Members of the drug transporter families MDR, MRP, and OATP have been identified in the BBB, and a detailed characterization of the involved proteins is now required to target drugs more efficiently to the brain.

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Quantized folding of plasmid DNA condensed with block catiomer into characteristic rod structures promoting transgene efficacy. Maxillary sinus floor elevation: a valuable pre-prosthetic procedure. Purification and characterization of the inducible a agglutinin of Saccharomyces cerevisiae. Instrumentation and physical factors related to visualization of stenotic and regurgitant jets by Doppler color flow mapping. Statistical Report of Central Nervous System Tumors Histologically Diagnosed in the Sichuan Province of China from 2008 to 2013: A West China Glioma Center Report.

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In this work, an alternative aerobic GF cereal fermentation by the levan producing AAB strains Gluconobacter albidus TMW 2.1191, Kozakia baliensis NBRC 16680 and Neoasaia chiangmaiensis NBRC 101099 was established in buckwheat doughs containing molasses as a natural source of sucrose. The human pathogen Campylobacter jejuni utilizes oxidative phosphorylation to meet all of its energy demands. Factors predicting the development of each type of psychosis were determined by serial multivariate logistic regression analyses. Although MTX therapy may result in accelerated involution or expulsion of placenta and has some beneficial effects on hemorrhagic events, but there is not enough evidence on its efficacy and safety to recommend its routine uses in all cases of invasive placenta. Overexpression of the SuUR gene induces reversible modifications at pericentric, telomeric and intercalary heterochromatin of Drosophila melanogaster polytene chromosomes.

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Caspases, a family of cysteine proteases structurally related to interleukin-1-beta-converting enzyme (ICE), play crucial roles in apoptosis induced by various stimuli, including Fas. The 250 kD antigen defined by MoAb 34.1 is similar to a high molecular weight proteoglycan reported to be an excellent tumor marker for human melanomas. GDM was diagnosed with at least two abnormal results and GIGT was diagnosed with one abnormal result. As demonstration examples, the propagation properties of insulator-metal-insulator and metamaterials (MMs) structures are also shown. Beyond epidemiological significance, the composite approach of the survey represents a promising intervention of CHD prevention, as almost one third of the target population was evaluated by GPs with subsequent implications for clinical practice. This new assay takes advantage of the palindromic recognition sequence of the restriction nucleases and the unique optical properties of AuNPs and is simpler than the procedure previously described by by Xu et al. We also competed the evolved host, transformed with the baseline plasmid, against its isogenic plasmid-free counterpart. Three hundred and ninety-three cases (male 189, female 204) were followed with an average age of 44.6 years old (range from 23 to 76). We hypothesized that a single bout of submaximal exercise would elicit increased nuclear accumulation of Nrf2, and that this response to exercise would be attenuated with aging. Familial Mediterranean fever and polyarteritis nodosa: experience of five paediatric cases.

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The combination arm had greater toxicity and may have been harmful in this study. With one exception, the mHealth programs identified were found to have low enrollment. Cell-associated bovine immunodeficiency virus (BIV) and cell-free BIV were subjected to increasing temperatures, including pasteurization conditions. In type 2 diabetes, sitagliptin, in combination with a sulphonylurea, only provides modest efficacy in terms of HbA1c levels and increases the risk of hypoglycaemia. In the years 1985-1995, however, the contribution of cerebrovascular disease decreased in both sexes, while that of heart disease grew to become the largest of any single condition. Gastric emptying was scintigraphically studied by labelling the solid component of a standard test meal.

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When tethered, these cells exhibited a normal rotational response but an inverse pausing response to chemotactic stimuli: the frequency of pauses decreased in response to repellents and increased in response to attractants. The current study suggests that the 6-item short form of the UW-SES has the same meaning across the four diagnostic subgroups. Octreotide in a Critically Ill Extremely Preterm Infant With Perforated Necrotizing Enterocolitis. The current study has identified such a mechanism that is centered on the regulation of caspase-8 activity. These are the carcinoid, atypical carcinoid, and the small cell carcinoma, which have been called neuroendocrine carcinomas of the lung. Autoimmune rheumatic diseases associated with HIV infection and its pathogenesis. A multiple wavelength, pulsed CO(2) lidar system operating at a pulse repetition frequency of 200 Hz and permitting the random selection of CO(2) laser wavelengths for each laser pulse is presented. The need for risk management to evolve to assure a culture of safety. 6 healthy, adult, mixed-breed dogs, anesthetized twice and receiving gentamicin (6 mg/kg of body weight, i.v.) or saline solution. We hypothesized that there is a relationship between CTGF expression and the induction of apoptosis in osteocytes, to play a significant role in triggering bone remodeling during experimental tooth movement.

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This review summarizes recent findings with the goal of relating structural variants of ATGL and CGI-58 to functional consequences in lipid metabolism. Hind muscle histology showed significant granulomatous reactions around the probe and mobic medication dose both types of microspheres. We will use GT as an example to show how genetic studies can help understand the cell biology, pathophysiology, and management of a group of rare diseases where many of the genetic causes remain to be elucidated. Pulmonary rehabilitation for dyspnea in the palliative-care setting. Liver inflammation and injury are mediated by the innate immune response, which is regulated by Toll-like receptors (TLR).

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Hospital Noninvasive Ventilation Case Volume and Outcomes of Acute Exacerbations of Chronic Obstructive Pulmonary Disease. Calculated at equal mass doses or in molecular terms, ghrelin appears to be a more potent stimulus than GHRP-6 and GHRH. Here, we show that dsRNA specifically suppresses the expression of HIV-1 genes. This approach not only provides the means for on-site analysis but also removes the time delay and sample alteration that can occur during transport to a centralized laboratory. To evaluate the effect of basic fibroblast growth factor (bFGF) on the famvir drug classification proliferation of canine corneal epithelial cells and epithelial wound healing. After collaborating with the Centers for Disease Control and Prevention to develop an evidence-based mammography intervention manual, the dissemination of the manual in a managed care setting was assessed. The aim of this paper is to provide a comprehensive review of the literature in this evolving field of medical imaging particularly focusing on three-dimensional analysis of facial movement and outlining the current concepts in objective analysis of the data set. The current pilot study developed and evaluated the impact of Work out by Walking (WOW), a multicomponent group walking intervention on the health of 16 individuals with SSDs. Ectopic bone formation is enhanced in senescent animals implanted with embryonic cells.

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