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Agoxin (Digoxin)
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Agoxin

Agoxin is a type of drug called a cardiac glycoside. Their function is to slow your heart rate down and improve the filling of your ventricles (two of the chambers of the heart) with blood. For people with atrial fibrillation, where the heart beats irregularly, a different volume of blood is pumped out each time.

Other names for this medication:
Agoxin, Cardiacin, Cardiogoxin, Digacin, Digibind, Digitek, Digobal, Digohan, Digoregen, Digosin, Digossina, Digoxen, Digoxin, Digoxine, Digoxinum, Eudigox, Fargoxin, Halfdigoxin, Lanadicor, Lanibos, Lanicor, Lenoxin, Purgoxin, Sigmaxin, Vidaxil

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Also known as: Digoxin

Description

Agoxin (digoxin) is derived from the leaves of a digitalis plant. Digoxin helps make the heart beat stronger and with a more regular rhythm.

Agoxin is used to treat heart failure.

Agoxin is also used to treat atrial fibrillation, a heart rhythm disorder of the atria (the upper chambers of the heart that allow blood to flow into the heart).

Dosage

This section provides information on the proper use of a number of products that contain digoxin. It may not be specific to Agoxin Pediatric. Please read with care.

To keep your heart working properly, take this medicine exactly as directed even though you may feel well. Do not take more of it than your doctor ordered and do not miss any doses. Take the medicine at the same time each day. This medicine works best when there is a constant amount in the blood.

When you are taking this medicine, it is very important that you get the exact amount of medicine that you need. The dose of digoxin will be different for different patients. Your doctor will determine the proper dose of digoxin for you. Follow your doctor's orders or the directions on the label.

Measure the oral solution correctly using the marked measuring dropper that comes with the package or an oral syringe. Do not use teaspoons and tablespoons that are used for serving and eating food. They do not measure exact amounts.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For heart failure or atrial fibrillation: For oral dosage form (solution): Adults, teenagers, and children 10 years of age and older—Dose is based on age, body weight, and medical condition and must be determined by your doctor. At first, the dose is usually 10 to 15 micrograms (mcg) per kilogram (kg) of body weight. Your doctor may adjust your dose as needed. However, the maintenance dose is usually 3 to 4.5 mcg per kg of body weight per day. Children 5 to 10 years of age—Dose is based on age, body weight, and medical condition and must be determined by your doctor. At first, the dose is usually 20 to 35 micrograms (mcg) per kilogram (kg) of body weight. Your doctor may adjust your dose as needed. However, the maintenance dose is usually 5.6 to 11.3 mcg per kg of body weight per day. Children 2 to 5 years of age—Dose is based on age, body weight, and medical condition and must be determined by your doctor. At first, the dose is usually 30 to 45 micrograms (mcg) per kilogram (kg) of body weight. Your doctor may adjust your dose as needed. However, the maintenance dose is usually 9.4 to 13.1 mcg per kg of body weight per day. Infants 1 month to 24 months of age—Dose is based on age, body weight, and medical condition and must be determined by your doctor. At first, the dose is usually 35 to 60 micrograms (mcg) per kilogram (kg) of body weight. Your doctor may adjust your dose as needed. However, the maintenance dose is usually 11.3 to 18.8 mcg per kg of body weight per day. Full-term babies—Dose is based on age, body weight, and medical condition and must be determined by your doctor. At first, the dose is usually 25 to 35 micrograms (mcg) per kilogram (kg) of body weight. Your doctor may adjust your dose as needed. However, the maintenance dose is usually 7.5 to 11.3 mcg per kg of body weight per day. Premature babies—Dose is based on age, body weight, and medical condition and must be determined by your doctor. At first, the dose is usually 20 to 30 micrograms (mcg) per kilogram (kg) of body weight. Your doctor may adjust your dose as needed. However, the maintenance dose is usually 4.7 to 7.8 mcg per kg of body weight per day. For oral dosage form (tablets): Adults—Your doctor will give your first few doses intravenously (rapid digitalization) and then, you'll be switched to oral tablets for maintenance therapy. A maintenance dose of 0.125 to 0.5 milligram (mg) once a day will be given depending on your body weight and medical condition. Teenagers and children older than 10 years of age—Dose is based on body weight and must be determined by your doctor. Children younger than 10 years of age—Use and dose must be determined by your doctor.

Overdose

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of digoxin can be fatal.

Overdose symptoms may include nausea, vomiting, loss of appetite, and feeling tired.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Detailed Agoxin dosage information

Side effects

The most common side effects associated with Agoxin are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

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Improvement in angiographic cerebral vasospasm after intra-arterial verapamil administration. Application of image enhancement techniques to magnetic resonance imaging. The present study assessed the overweight/obesity prevalence and associated factors in middle class adolescents of a school in the city of Niteroi, Rio de Janeiro, Brazil, and evaluated the correlation between body mass index with anthropometric measures of fatness. This is consistent with analyses of age-specific cancer death rate and cumulative survival, indicating a significant slowing of the increase in cancer death and all cause death with aging. In phase II, the therapeutic activity of the maximum-acceptable dose (MAD) of tosedostat was evaluated in elderly and/or relapsing patients with acute myeloid leukemia (AML) or myelodysplastic syndrome. Dorsal root ganglia sensory and spinal cord alpha-motoneurons acquire HNMP-1 protein selectively throughout development. By analogy to epigenetic phenomena in several eukaryotes, our results suggest a possible role for (hetero)chromatic chromosomal domains in transcriptional inactivation. Effective management of trauma-related invasive fungal wound infections (IFIs) depends on early diagnosis and timely initiation of treatment.

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Evidence that endogenous enkephalins produce delta-opiate receptor mediated neuronal inhibitions in rat dorsal horn. This study aimed to explore subglottal convergence angle measurement. Purification and properties of polycation-stimulated phosphorylase phosphatases from rabbit skeletal muscle. In this review we will primarily review their use for ectopic gene expression and lineage analysis to study cell differentiation in murine and chick embryos. These studies also failed to demonstrate greater immunoreactivity of sera from patients as opposed to the immunoreactivity of sera from healthy controls. Patients with familial intracranial aneurysms (IA) have a higher risk of rupture than patients with sporadic IA. Initial experience of restorative proctocolectomy for ulcerative colitis by transanal total mesorectal rectal excision and single-incision abdominal laparoscopic surgery. Altered calcium homeostasis was associated with an increased risk of having MetS and diabetes in this demographic group.

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Quality of life and sexuality of women treated for breast cancer. There are various barriers toward accurate utilization of HTAs in Iran. Clinical and biochemical phenotypes of adults with monoallelic and biallelic CYP24A1 mutations: evidence of gene dose effect. Chloroquine (CQ), a drug that has been used extensively for the prevention and treatment of malaria, is currently considered safe for use during pregnancy. The influence of glycaemia on vagal activity and gastric emptying rate probably alters the optimal time interval between insulin injections and postprandial increases in the blood glucose concentration in patients treated with short-acting insulin administered at mealtimes. Therefore, we currently examined the adrenergic modulation of conditioned suppression of splenocyte function. All 34 flaps survived completely and the reconstructed penis had immediate postoperative tactile sensibility.

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The diagnosis of Jadassohn-Lewandowsky syndrome was based on characteristic skin and eye disturbances. Cytotoxicity was observed in ethanol-treated hepatocytes incubated with immunoglobulin G from patients with ALD and normal human blood mononuclear cells. Successful and unsuccessful users of bilateral amplification: differences and similarities in binaural performance. Infants and toddlers are at increased risk for severe/fatal abuse, often at the hands of male perpetrators. This induction was not related to COX-2 expression, suggesting that LPS-induced NFkappaB activation is independent of COX-2. Future directions for study of the therapeutic relationship are discussed. The present paper describes the systematic development of a theory-based computer-tailored intervention, YouRAction, which targets individual and environmental factors determining PA among adolescents. The c-kit expression, typical of GISTs but observed also in other epithelial and neuroendocrine tumors, not only broadens the possibility to gain insight into the carcinogenesis of these neoplasms, but also opens the field to plavix 20 mg possible new therapeutic opportunities using multitargeted molecules.

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One hundred and thirty-eight patients (15-50 years) admitted to hospital (general ward or intensive care unit) with acute asthma were prospectively assessed using a number of previously validated instruments. In addition, effects of subchronic D-tagatose ingestion on fasting plasma phosphorus, magnesium, lipids, and glucose homeostasis were studied. This inhibition of mycorrhization was reversed by an organic N source only utilizable by the fungus. Therefore, they must be enhanced before they are examined by medical professionals. A new electrochemical sensor for melamine with 3,4-dihydroxyphenylacetic acid as the recognition element is established. Studies of Tonsils in Basic and Clinical Perspectives: From the Past to the Future. The distribution of trace elements (TEs) in water, sediment, riparian soil and dominant plants was investigated in the Fenghe River, Northwestern China.

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Ventricular pacing with a novel gastroesophageal electrode: a comparison with external pacing. Using disease-specific, patient-reported measures in everyday clinic. Cognitive solutions are trained to understand technical, industry-specific content and use advanced reasoning, predictive modeling, and machine learning techniques to advance research faster. Impact of diabetic foot ulcer on health-related quality of life: A cross-sectional study. A close association of risk factors in young adults, 20-38 years of age, occurs with IMT, and a marked increase is noted as numbers of risk factors increase. Volume reduction may be appropriate as a treatment for dyspnea in patients with pulmonary emphysema. In spite of strong evidence showing that brain infarction can be reduced by inhibiting any one of the above biochemical events, such as targeting excitotoxicity, up-regulation of an antiapoptotic gene, or inhibition of a down-stream effector caspase, it is becoming clear that targeting a single gene or factor is not sufficient for stroke therapeutics. Satisfaction was generally high, and participants reported benefits related to manuscript review training and professional development.

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Three-dimensional kinematic and kinetic gait deviations in individuals with chronic anterior cruciate ligament deficient knee: A systematic review and meta-analysis. Recently, an RT 3D TEE probe has been developed to produce high-quality real-time images. Molecular analysis of the 5 alpha-reductase type 2 gene in a patient with confirmed biochemical 5 alpha-reductase deficiency has resulted in the identification of a novel mutation, GAA to will cipro help an ear infection AAA, at codon 200. However, reverse transcriptase-polymerase chain reaction (RT-PCR) with degenerate G-protein oligonucleotide primers, followed by hybridisation analysis, using oligonucleotides specific for individual G-protein alpha-subunits, not only confirmed expression of Go, but also detected Gi1 and G11 alpha-subunits. We previously showed that HcDPPIVB is the gene responsible for the majority of secreted DppIV activity in H. RA FLS, but not OA FLS, induced B cells to re-express RAG mRNA and proteins. cDNA sequence and tissue distribution of the mRNA for bovine and murine p11, the S100-related light chain of the protein-tyrosine kinase substrate p36 (calpactin I).

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The majority had congenital pelviureteric junction obstruction and results of early reconstructive surgery were satisfactory. Emerging nanomedicines for early cancer detection and improved treatment: current perspective and future promise. The clinical importance of the platelet alloantigens is due to their ability to elicit alloantibody production. The mean follow-up period after subsequent operation was 90 months (range, 78-104 mo). Abnormal liver function tests (LFTs) are a common manifestation of heart failure (HF). Acoustic data collected from a 22 m long horizontal line array with elements comprised of omni-directional hydrophone sensors co-located with acceleration vector sensor triplets are analyzed for seabed geo-acoustic information. Patients in the control group followed the usual bactrim class of antibiotic care protocol with no exercise intervention. Trophic effects of the neuroprotective agent selegiline on cultured dopaminergic neurons were investigated and compared with the effects produced by brain derived neurotrophic factor (BDNF).

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