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Addos (Nifedipine)

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Addos is a dihydropyridine calcium channel blocker. Addos is used to: treat high blood pressure (hypertension), prevent chronic stable angina (chest pain). Addos was the first calcium channel blocker to be shown to significantly reduce the development of new overt heart failure in patients with coronary artery disease. Excellent blood-pressure control in recent clinical trials has been shown to result in significant protection against stroke. Addos works by opening up blood vessels in the body to lower blood pressure and improve the supply of blood and oxygen to the heart. Calcium channel blockers do not change the amount of calcium in your blood or bones.

Other names for this medication:
Adalate, Adefin, Buconif, Calchan, Calcianta, Cardicon, Cardiosol, Cardipin, Chronadalate, Corinfar, Epilat, Fenamon, Fenidina, Ficard, Herlat, Marivolon, Milfadin, Myogard, Nidilat, Nidipine, Nifatenol, Nifcal, Nifecap, Nifecardia, Nifedalat, Nifedel, Nifedigel, Nifedine, Nifedip, Nifedipin, Nifehexal, Nifensar, Nifezzard, Nirena, Nycopin, Oxcord, Siopelmin, Tensomax, Valni, Zenusin

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Also known as: Nifedipine


Nifedipine is used alone or together with other medicines to treat severe chest pain (angina) or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Nifedipine is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, nifedipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.


This section provides information on the proper use of a number of products that contain nifedipine. It may not be specific to Addos. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

Swallow the extended release tablet whole. Do not break, crush, or chew it. It is best to take this tablet on an empty stomach.

If you are taking the extended-release tablets, part of the tablet may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For treatment of chest pain or high blood pressure: For oral dosage form (capsules): Adults—At first, 10 milligrams (mg) three times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 30 or 60 milligrams (mg) once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 90 mg once a day. Children—Use and dose must be determined by your doctor.


If you overdose Addos and you don't feel good you should visit your doctor or health care provider immediately.


Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Addos are:

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Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

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Opportunistic infections often coexist with human immunodeficiency virus (HIV) infection in brain. Combined isoniazid and PAS in therapy of experimental tuberculosis. Low-dose-rate radiation sensitivity of a human hepatoma cell line. Post-traumatic complex regional pain syndrome: clinical features and epidemiology. Digoxin for the treatment of chronic and acute heart failure syndromes. Transforming the system time domain representation to the frequency domain generates five system parameters that can be valuable for process identification utility: steady state gain, time constant, system order, and magnitude ratio and phase shift over a wide frequency range. Cocaine-induced alterations in the density of monoaminergic receptors in the embryonic guinea pig cerebral wall. Seamless coordination of cell growth with cell envelope elongation at the pole maintains this barrier.

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Association of increased intramyocellular lipid content with insulin resistance in lean nondiabetic offspring of type 2 diabetic subjects. There is now a series of findings with individuals who have been exposed to HIV but are HIV-seronegative that suggest a protective role for CTLs. While stuck on a single general pollination system, Leandra s.str. Release from nocodazole G2/M block or treatment with phosphatase caused the more slowly migrating species of EBNA-LP to disappear. Tissues were washed to baseline length and equilibrated with a given concentration of test drugs. The Sorin Pericarbon stentless valve is an easily implantable valve replacement device. An outer membrane permeability mechanism, independent of changes in lipopolysaccharide content, mediating susceptibility to the oxygen-independent antimicrobial activity of rat polymorphonuclear leukocyte granule contents is suggested. Haemangiomas are treated surgically only when lip function is substantially impaired. Knowledge and attitudes about OC may not always reflect trends in use. To minimize the risk of incontinence and impotence without compromising oncological outcome, we performed prostate sparing surgery during radical cystectomy for bladder cancer.

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The aim of the present work was to examine whether the increase in E2F1 protein levels observed after DNA damage is only a reflection of an increase in E2F1 protein stability or is also the consequence of enhanced transcription of the E2F1 gene. Colorectal Cancer with BRAF D594G Mutation Is Not Associated with Microsatellite Instability or Poor Prognosis. It is concluded that although the syndrome can be well recognized, it is not acknowledged in standard diagnostic manuals, hence the relative neglect in the epilepsy literature. We suggest that future work should be directed towards investigating the potential role of abnormalities of this phase in the aetiology of CD. In case of the polyethylene glycol-potassium phosphate system, droplet coalescence was found to play a critical role in phase demixing. Granulometric analysis was carried out by laser diffractometry using a method which made it possible to assess the mean thickness of the lamellar particles. A multi-centre clinical trial was conducted in three paediatric hospitals in Australia. We compared the incidence of complications before and after ileovesicostomy as well as long-term urinary tract status.

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We report the rare case of a 43-year-old woman with a simultaneous meningioma of the sphenoid wing and an amyloid-containing prolactinoma. In-bore magnetic resonance-guided transrectal biopsy for the detection of clinically significant prostate cancer. The aim of this study was to elucidate the mechanism responsible for such findings. Brainstem-spinal cord connections play an essential role in adult pain processing, and the modulation of spinal pain network excitability by brainstem nuclei is known to contribute to hyperalgesia and chronic pain. At aged 35 years, Spigelman Stage IV duodenal adenomatosis was detected. These results suggest that the spin-adducts are products of nitrosobenzene with retinoid radicals in which the retinoid radicals retain their original chemical structures. When physicians resist early elective IUD removal, it may impact patient satisfaction and even jeopardize the doctor-patient relationship.

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Top 10 Facts You Should Know about Hearing Loss and Cognitive Decline. Myelin-associated proteins contribute to failure of axon regeneration in the injured central nervous system of the how long does arcoxia 60 mg last adult. This review evaluated recent evidence related to the effect of balance training on balance performance among individuals poststroke across the continuum of recovery. Contact inhibition-induced inactivation of the cyclin D-dependent kinase in rat fibroblast cell line, 3Y1. Company records provided information on occupational exposure and data on smoking habits were obtained from a next of kin of each subject. A method is presented for the estimation of the nonlinearity of a photodetector.

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Rituximab in children with steroid-dependent nephrotic syndrome: experience of a tertiary center and review of the literature. In addition to intrinsic GAP activity, one tail with high GAP activity and others with low or minimal activity potentiated the GAP activity of intact PLC-beta1. However, its biological functions and regulation mechanisms are still unclear. This is achieved by a precise selection of the foam samples and by the fabrication of new air-coupled transducers that enlarge the experimental working frequency range to lower frequencies. To investigate whether adaptive statistical iterative reconstruction (ASiR) or model-based iterative reconstruction (MBIR) improves the diagnostic performance of computed tomography angiography (CTA) for small-vessel calcified lesions relative to filtered back projection (FBP) using cadaver extremities and a calcified stenosis phantom. Development and validation of a microRNA-based signature (MiROvaR) to predict early relapse or progression of epithelial ovarian cancer: a cohort study. Multicenter trial validation of a camera-based method to measure Tc-99m mercaptoacetyltriglycine, or Tc-99m MAG3, clearance. These polyps are frequently sessile or flat, located in the proximal colon, and may be overlooked during colonoscopy. To investigate the association of polymorphisms in complement factor H (CFH) and coronary heart disease (CHD) using meta-analysis.

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Von Hippel-Lindau disease: strategies in early detection (renal-, adrenal-, pancreatic masses). They include avoiding bowel preparation and postoperative nasogastric tube, early feeding, non-narcotic pain management, and the use of cholinergic and mu-receptor opioid antagonists. Although this may be a necessary step in kin selection, no clear associated improvement in individual or group fitness has been reported to qualify as such. Refined mapping of 12q13-q15 amplicons in human malignant gliomas suggests CDK4/SAS and MDM2 as independent amplification targets. Linking joint commission inpatient core measures and national patient safety goals with evidence.

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We conducted a logistic regression analysis to examine the association between migraine and the allelic and haplotype variants. The inhibitory effects of iberiotoxin and 4-aminopyridine on the relaxation induced by beta 1- and beta 2-adrenoceptor activation in rat aortic rings. Conjugation of oligonucleotides to lipophilic groups can improve delivery to cells but the enhanced cellular binding may also facilitate nonspecific interactions. Potential manipulation of events at the vasculature by the parasite requires further investigation. Impeding Bacillus spore germination in vitro and bisoprolol fumarate 5mg tablet in milk by soy glycinin during long cold storage. To describe four patients having total anomalous pulmonary venous connection with an intrapulmonary vertical vein, rendering difficulty in diagnosis and surgery.

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A group of 211 pre-presbyopic clinical subjects were tested with MEM for purposes of comparing the central tendency measures of a clinical population to established normative data and determining whether MEM varied with refractive status or near phoria. The basic idea is to assume that one of the systems becomes fixed after some time and serves as a source of morphogens for the other system. To our knowledge, very few cases of tamoxifen-induced pancreatitis have been reported in the literature. The development of skeletal muscle is a highly regulated process governed by the four myogenic regulatory factors (MRFs) MyoD, myf-5, myogenin, and MRF4. These results indicate that the addition of cryotherapy to a regime of exercises following arthroscopic knee surgery produced benefits of increased compliance, improved weight-bearing status, and lower prescription medication consumption.

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Potential energy surface studies via a single root multireference coupled cluster theory. The results revealed that there were few differences in task completion time and root-mean-square error (RMSE) between the two types of joysticks. The resultant network model, obtained in the first stage, may however be redundant. Request forms were analyzed for clinical bio-data flagyl bv dosing , diagnosis and nature of biopsies. Combination bacteriolytic cancer therapy: Attacking cancer from inside out. Hence, the real possibility of amplifying oxidizing damage must be considered when planning treatment with DFO, and failure of DFO to inhibit a particular response to oxidizing stress or its enhancement by DFO cannot, by itself, be considered sufficient evidence to rule out an iron-dependent process. A more elaborate specification of the desired performance is now possible. The initial sequences analysis of the 16S rDNA gene conformed that one of the isolates (SD551) falls within the phylogenetic clade, which encompasses the genus Streptomyces.

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Women with a history of chronic hypertension, diabetes or renal disease were excluded. Calcium phosphate mineralization beneath a polycationic monolayer at the air-water interface. Hybridization studies with Tn916 DNA indicated that the transposon is present in EcoRI and HindIII fragments of the nonhemolytic mutants. Confocal microscopy analysis shows that beta-catenin colocalizes with LMW-PTP at the plasma membrane. The aim of this review is to show that high resolution 31P NMR spectroscopy is a convenient and precise analytical tool for the phospholipid analysis of extracts from biological samples (tissues and body fluids). Two prosthetic ligaments, the Kennedy LAD and Gore-Tex, are FDA approved for limited indications. The quinoxaline 2, which lacks an alpha,beta-unsaturated group, has no effect on mitochondrial respiration using concentrations which inhibit the growth of M.

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Exploring the relationships between maternal and child metacognitions and child anxiety. A basic treatment for arterial hypertension with extracts of the roots of Morinda citrifilia (Cay-Nhau). Crucial role of the central leptin receptor in murine Trypanosoma cruzi (Brazil strain) infection. Empirical formulas for calculating use of ethambutol medicine loss in hollow core tube lattice fibers. In this study we describe the extent of the tracheal and bronchial narrowing, the changes in airway diameter during respiration and the effects of these obstructions on respiratory function in adult MPSII patients.

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To investigate the types of workarounds users employed, the underlying reasons offered and implications for care provision and patient safety. CO oxidation over AuPd(100) from ultrahigh vacuum to near-atmospheric pressures: the critical role of contiguous Pd atoms. Accordingly, transfer of contact positions to a 3D MRI brain-surface rendering was carried out manually by using the rendering software. In contrast, there were 24 base-pair differences between Tn2 and Tn3, most of them clustered in one segment of the tnpR gene. Candy sprays have an extremely low pH (1.9-2.3) and a neutralisable acidity varying between 0.8-1.6 ml of 0.25M NaOH. A sample of 2094 adolescents from the HELENA cross-sectional study was selected.

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