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Addos (Nifedipine)
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Addos

Addos is a dihydropyridine calcium channel blocker. Addos is used to: treat high blood pressure (hypertension), prevent chronic stable angina (chest pain). Addos was the first calcium channel blocker to be shown to significantly reduce the development of new overt heart failure in patients with coronary artery disease. Excellent blood-pressure control in recent clinical trials has been shown to result in significant protection against stroke. Addos works by opening up blood vessels in the body to lower blood pressure and improve the supply of blood and oxygen to the heart. Calcium channel blockers do not change the amount of calcium in your blood or bones.

Other names for this medication:
Adalate, Adefin, Buconif, Calchan, Calcianta, Cardicon, Cardiosol, Cardipin, Chronadalate, Corinfar, Epilat, Fenamon, Fenidina, Ficard, Herlat, Marivolon, Milfadin, Myogard, Nidilat, Nidipine, Nifatenol, Nifcal, Nifecap, Nifecardia, Nifedalat, Nifedel, Nifedigel, Nifedine, Nifedip, Nifedipin, Nifehexal, Nifensar, Nifezzard, Nirena, Nycopin, Oxcord, Siopelmin, Tensomax, Valni, Zenusin

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Also known as: Nifedipine

Description

Nifedipine is used alone or together with other medicines to treat severe chest pain (angina) or high blood pressure (hypertension). High blood pressure adds to the workload of the heart and arteries. If it continues for a long time, the heart and arteries may not function properly. This can damage the blood vessels of the brain, heart, and kidneys, resulting in a stroke, heart failure, or kidney failure. High blood pressure may also increase the risk of heart attacks. These problems may be less likely to occur if blood pressure is controlled.

Nifedipine is a calcium channel blocker. It works by affecting the movement of calcium into the cells of the heart and blood vessels. As a result, nifedipine relaxes blood vessels and increases the supply of blood and oxygen to the heart while reducing its workload.

This medicine is available only with your doctor's prescription.

Dosage

This section provides information on the proper use of a number of products that contain nifedipine. It may not be specific to Addos. Please read with care.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many may feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

Swallow the extended release tablet whole. Do not break, crush, or chew it. It is best to take this tablet on an empty stomach.

If you are taking the extended-release tablets, part of the tablet may pass into your stool after your body has absorbed the medicine. This is normal and nothing to worry about.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For treatment of chest pain or high blood pressure: For oral dosage form (capsules): Adults—At first, 10 milligrams (mg) three times a day. Your doctor may increase your dose as needed. Children—Use and dose must be determined by your doctor. For oral dosage form (extended-release tablets): Adults—At first, 30 or 60 milligrams (mg) once a day. Your doctor may increase your dose as needed. However, the dose is usually not more than 90 mg once a day. Children—Use and dose must be determined by your doctor.

Overdose

If you overdose Addos and you don't feel good you should visit your doctor or health care provider immediately.

Storage

Store at room temperature between 15 and 25 degrees C (59 and 77 degrees F) away from moisture and heat. Keep container tightly closed. Throw away any unused medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Addos are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.

Contraindications

Studies in women suggest that this medication poses minimal risk to the infant when used during breastfeeding.

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Opportunistic infections often coexist with human immunodeficiency virus (HIV) infection in brain. Combined isoniazid and PAS in therapy of experimental tuberculosis. Low-dose-rate radiation sensitivity of a human hepatoma cell line. Post-traumatic complex regional pain syndrome: clinical features and epidemiology. Digoxin for the treatment of chronic and acute heart failure syndromes. Transforming the system time domain representation to the frequency domain generates five system parameters that can be valuable for process identification utility: steady state gain, time constant, system order, and magnitude ratio and phase shift over a wide frequency range. Cocaine-induced alterations in the density of monoaminergic receptors in the embryonic guinea pig cerebral wall. Seamless coordination of cell growth with cell envelope elongation at the pole maintains this barrier.

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Association of increased intramyocellular lipid content with insulin resistance in lean nondiabetic offspring of type 2 diabetic subjects. There is now a series of findings with individuals who have been exposed to HIV but are HIV-seronegative that suggest a protective role for CTLs. While stuck on a single general pollination system, Leandra s.str. Release from nocodazole G2/M block or treatment with phosphatase caused the more slowly migrating species of EBNA-LP to disappear. Tissues were washed to baseline length and equilibrated with a given concentration of test drugs. The Sorin Pericarbon stentless valve is an easily implantable valve replacement device. An outer membrane permeability mechanism, independent of changes in lipopolysaccharide content, mediating susceptibility to the oxygen-independent antimicrobial activity of rat polymorphonuclear leukocyte granule contents is suggested. Haemangiomas are treated surgically only when lip function is substantially impaired. Knowledge and attitudes about OC may not always reflect trends in use. To minimize the risk of incontinence and impotence without compromising oncological outcome, we performed prostate sparing surgery during radical cystectomy for bladder cancer.

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The aim of the present work was to examine whether the increase in E2F1 protein levels observed after DNA damage is only a reflection of an increase in E2F1 protein stability or is also the consequence of enhanced transcription of the E2F1 gene. Colorectal Cancer with BRAF D594G Mutation Is Not Associated with Microsatellite Instability or Poor Prognosis. It is concluded that although the syndrome can be well recognized, it is not acknowledged in standard diagnostic manuals, hence the relative neglect in the epilepsy literature. We suggest that future work should be directed towards investigating the potential role of abnormalities of this phase in the aetiology of CD. In case of the polyethylene glycol-potassium phosphate system, droplet coalescence was found to play a critical role in phase demixing. Granulometric analysis was carried out by laser diffractometry using a method which made it possible to assess the mean thickness of the lamellar particles. A multi-centre clinical trial was conducted in three paediatric hospitals in Australia. We compared the incidence of complications before and after ileovesicostomy as well as long-term urinary tract status.

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We report the rare case of a 43-year-old woman with a simultaneous meningioma of the sphenoid wing and an amyloid-containing prolactinoma. In-bore magnetic resonance-guided transrectal biopsy for the detection of clinically significant prostate cancer. The aim of this study was to elucidate the mechanism responsible for such findings. Brainstem-spinal cord connections play an essential role in adult pain processing, and the modulation of spinal pain network excitability by brainstem nuclei is known to contribute to hyperalgesia and chronic pain. At aged 35 years, Spigelman Stage IV duodenal adenomatosis was detected. These results suggest that the spin-adducts are products of nitrosobenzene with retinoid radicals in which the retinoid radicals retain their original chemical structures. When physicians resist early elective IUD removal, it may impact patient satisfaction and even jeopardize the doctor-patient relationship.

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Rituximab in children with steroid-dependent nephrotic syndrome: experience of a tertiary center and review of the literature. In addition to intrinsic GAP activity, one tail with high GAP activity and others with low or minimal activity potentiated the GAP activity of intact PLC-beta1. However, its biological functions and regulation mechanisms are still unclear. This is achieved by a precise selection of the foam samples and by the fabrication of new air-coupled transducers that enlarge the experimental working frequency range to lower frequencies. To investigate whether adaptive statistical iterative reconstruction (ASiR) or model-based iterative reconstruction (MBIR) improves the diagnostic performance of computed tomography angiography (CTA) for small-vessel calcified lesions relative to filtered back projection (FBP) using cadaver extremities and a calcified stenosis phantom. Development and validation of a microRNA-based signature (MiROvaR) to predict early relapse or progression of epithelial ovarian cancer: a cohort study. Multicenter trial validation of a camera-based method to measure Tc-99m mercaptoacetyltriglycine, or Tc-99m MAG3, clearance. These polyps are frequently sessile or flat, located in the proximal colon, and may be overlooked during colonoscopy. To investigate the association of polymorphisms in complement factor H (CFH) and coronary heart disease (CHD) using meta-analysis.

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Von Hippel-Lindau disease: strategies in early detection (renal-, adrenal-, pancreatic masses). They include avoiding bowel preparation and postoperative nasogastric tube, early feeding, non-narcotic pain management, and the use of cholinergic and mu-receptor opioid antagonists. Although this may be a necessary step in kin selection, no clear associated improvement in individual or group fitness has been reported to qualify as such. Refined mapping of 12q13-q15 amplicons in human malignant gliomas suggests CDK4/SAS and MDM2 as independent amplification targets. Linking joint commission inpatient core measures and national patient safety goals with evidence.

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