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Adapalene is a third-generation topical retinoid primarily used in the treatment of mild-moderate acne, and is also used off-label to treat keratosis pilaris as well as other skin conditions. Among topical retinoids used to treat acne vulgaris, Adapalene is considered to be the least effective, but best tolerated.

Other names for this medication:
Aclene, Acneril, Acneris, Acniriv, Acnovate, Adaferin, Adapalene, Adapen, Adaple, Adaret, Adgraze, Adiff, Adina, Aditop, Adlene, Alangel, Apalene, Apgel, Clinred, Daple, Deriva, Difra, Edplin, Faceclin, Labopene, Medapine, Rozac, Soflene, Vandep, Zolvee

Similar Products:
Benicar, Nexium, Risperdal, Trandate, Hydrea, Cymbalta, Amoxil, Nibend, Enalaprilum, Trihexonex, Iopar, Typhon, Indoflam, Voltadin, Pantox,


Adapalene (adapalene) is a topical medicine (a medication that is applied to the surface of the skin) similar to vitamin A. It helps the skin to renew itself.

Adapalene is used to treat severe acne in people who are at least 12 years old. It works by decreasing acne formation.


Follow the directions for using this medicine provided by your doctor. Use Adapalene exactly as directed. Adapalene is best applied after washing and drying your skin. Apply a thin layer of gel to the affected areas once daily at bedtime. Avoid the eyes, lips and nose. Do not allow this preparation to come into contact with the mucous membranes (e.g. mouth, vagina, inside of nose etc.). Try not to touch the treated areas overnight. Do not use any harsh soaps or exfoliants while you are being treated with Adapalene. Adapalene should not be used on broken, sunburnt or infected skin. You may notice a slight change of colour of the skin you are applying this preparation to. This is only temporary and should return to normal soon after finishing treatment with Adapalene. Continue using Adapalene until no new acne spots appear. You may need to use it for several months. You should notice some clinical improvement after 4-8 weeks and more improvement after further use. There may be a worsening of acne during the first few weeks of therapy because Adapalene promotes the growth of pimples that have begun to form but are not yet visible. Therefore, treatment should not be stopped if acne appears to be worsening. Use a sunscreen cream and wear protective clothing if exposure to strong or prolonged sunlight cannot be avoided. Weather extremes such as wind or cold may also be irritating.


If you overdose Adapalene and you don't feel good you should visit your doctor or health care provider immediately.


Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Detailed Adapalene dosage information

Side effects

The most common side effects associated with Adapalene are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


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New method (T-H-E) in medical therapy of fibrocaseous and cavitary forms of pulmonary tuberculosis. A miniature, interstitial x-ray generator has recently been developed and is currently undergoing clinical trials for the treatment of brain tumors. The outer membrane protein, OprF, and the rhl quorum sensing circuit are two previously unrecognized cellular factors that are required for optimal anaerobic biofilm viability. Rivaroxaban crushed tablet suspension characteristics and relative bioavailability in healthy adults when administered orally or generic name ventolin via nasogastric tube. However, the emphasis on honey bees and neonicotinoids has led to neglect of the relevance of stingless bees, the prevailing pollinators of natural and agricultural tropical ecosystems, and of other agrochemicals, including other pesticides and even leaf fertilizers. Upper respiratory and digestive tract malignancies after liver transplantation for alcoholic cirrhosis. Histological assessment revealed a large intramural schwannoma of the gastric wall, arising from the submucosal layer. Results to date indicate the model is effective in producing comparable changes associated with blood volume, erythropoiesis, cardiac mass, baroreceptor responsiveness, carbohydrate metabolism, post-flight VO2max, and post-flight cardiac output during exercise. Upon phase partitioning in the nonionic detergent Triton X-114, the three receptor polypeptides behaved as a hydrophilic protein complex exhibiting phospholipid binding.

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Enucleated platelets (PLTs) utilize posttranscriptional gene (mRNA) regulation (PTGR) for their normal morphologic and physiologic functions, which are altered in their ex vivo storage, also collectively referred to as storage lesions. Two splice variants of a tyrosine phosphatase differ in substrate specificity, DNA binding, and subcellular location. Mild reduction in the activity of the alpha-ketoglutarate dehydrogenase complex elevates GABA shunt and glycolysis. Human cytomegalovirus binding to DC-SIGN is required for dendritic cell infection and target cell trans-infection. Patients who undergo a salvage esophagectomy mometasone formoterol inhaler brand name have a significantly higher risk of pulmonary and cardiac complication, and have high rates of repeated surgery.

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Association of ambient fine particles with out-of-hospital cardiac arrests in New York City. Here, we review the literature on normal wound healing and the pathological forms of wound healing, such as hypertrophic or excessive scar formation, with special emphasis on the heme-heme oxygenase (HO) system and the versatile effector molecules that are formed after HO-mediated heme degradation. Efficient synthesis of Idraparinux, the anticoagulant pentasaccharide. Although lumbosacral discectomy and implant insertion can be performed using the laparoscopic technique, the construct may not have the same biomechanical strength as that attained with the open procedure. Using partial peptide sequences generated from proteins in purified eIF3, we cloned the TIF31 and TIF32 genes encoding 135- (p135) and 110-kDa (p110) proteins. Probability of clearing an oncogenic HPV infection and duration of oncogenic HPV infections by smoking status was assessed. Quantitative assessment of psychomotor recovery after sedation and analgesia for outpatient EGD. The aim of our study is to validate a questionnaire to assess the consequences of pain in work productivity. A joint labor-management health and safety model: Lessons learned at the World Trade Center Emergency Project. Whether nutritional improvement correlates with functional recovery in convalescent stroke patients is unclear cleocin type of antibiotic .

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Several important issues in the field regarding the problems of substrate specificity, product inhibition, reaction reversibility, enzyme stability and catalytic efficiency are addressed in the representative synthesis of carbohydrates and carbohydrate mimetics designed for use to study carbohydrate-mediated cell adhesion. Mediastinal tuberculosis (TB) is rare and a diagnostic challenge. Studies in the chinchilla model have started to bring a rational basis to drug selection and dosing. This suggests that children are an additional source of infection, probably due to close and frequent physical contact outside the immediate family. The self what are the side effects of the drug actos -healing group key distribution (SGKD) scheme is a promising cryptographic tool, which can be used to distribute and update the group key for the secure group communication over unreliable wireless networks. The management of unilateral vocal cord palsy by augmentation using autologous fat. This study investigated the effects of nicotine on distractibility in 21 (11 males) nonsmokers with event-related potentials (ERPs) and behavioral performance measures extracted from an auditory discrimination task requiring a choice reaction time response to short- and long-duration tones, with and without imbedded deviants.

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