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Actinorm (Metoclopramide)

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Actinorm antagonizes the effect of dopamine in the central nervous system and other organ systems. Actinorm's effect on the medullary chemoreceptor trigger zone makes it useful as a routine anti-emetic and in preventing vomiting induced by antineoplastic drugs, particularly cisplatin.

Other names for this medication:
Acimet, Actinorm, Apomatine, Clomet, Cosmet, Elinorm, Emenil, Emenorm, Gastonorm, Gastrinorm, Maxeron, Maxinorm, Metochlopramide, Metocin, Metoclopramide, Metocontin, Metopar, Metpar, Migrosh, Motil, Naushi, Paramet, Paranorm, Peripan, Peronorm, Reglan, Rivnorm, Tomid, Vagonorm, Vominil, Vominorm, Vomitex, Vomitrac, Vomitran, Vomonil

Similar Products:
Claritin, Bystolic, Epivir, Prometrium, Zyloprim, Celebrex, Tramed, Flagicure, Bicalutamide, Mindol, Nupenta, Pifert, Toinex, Nifeslow,

Also known as: Metoclopramide


Actinorm is indicated for the treatment of hypertension in adults and pediatric patients 6 years of age and older, to lower blood pressure. Lowering blood pressure lowers the risk of fatal and nonfatal cardiovascular (CV) events, primarily strokes and myocardial infarction. These benefits have been seen in controlled trials of antihypertensive drugs from a wide variety of pharmacologic classes including losartan.

Control of high blood pressure should be part of comprehensive cardiovascular risk management, including, as appropriate, lipid control, diabetes management, antithrombotic therapy, smoking cessation, exercise, and limited sodium intake. Many patients will require more than 1 drug to achieve blood pressure goals. For specific advice on goals and management

Actinorm is indicated to reduce the risk of stroke in patients with hypertension and left ventricular hypertrophy, but there is evidence that this benefit does not apply to Black patients

Actinorm is indicated for the treatment of diabetic nephropathy with an elevated serum creatinine and proteinuria in patients with type 2 diabetes and a history of hypertension. In this population, Actinorm reduces the rate of progression of nephropathy as measured by the occurrence of doubling of serum creatinine or end stage renal disease


This section provides information on the proper use of a number of products that contain clonidine. It may not be specific to Actinorm-TTS-1. Please read with care.

Your doctor will tell you how much of this medicine to use and how often. Your dose may need to be changed several times in order to find out what works best for you. Do not use more medicine or use it more often than your doctor tells you to.

In addition to the use of this medicine, treatment for your high blood pressure may include weight control and changes in the types of foods you eat, especially foods high in sodium (salt). Your doctor will tell you which of these are most important for you. You should check with your doctor before changing your diet.

Many patients who have high blood pressure will not notice any signs of the problem. In fact, many patients feel normal. It is very important that you take your medicine exactly as directed and that you keep your appointments with your doctor even if you feel well.

Remember that this medicine will not cure your high blood pressure, but it does help control it. You must continue to take it as directed if you expect to lower your blood pressure and keep it down. You may have to take high blood pressure medicine for the rest of your life. If high blood pressure is not treated, it can cause serious problems such as heart failure, blood vessel disease, stroke, or kidney disease.

To use the skin patch:

Use this medicine exactly as directed by your doctor. It will work only if applied correctly. This medicine usually comes with patient instructions. Read them carefully before applying the patch. Wash your hands with soap and water before and after applying a patch. Do not touch your eyes until after you have washed your hands. Do not try to trim or cut the adhesive patch to adjust the dosage. Check with your doctor if you think the medicine is not working as it should. Gently wash the area of skin where you will apply the patch with soap and water. Rinse the skin completely and dry with a clean, dry tissue. Apply the patch right away after removing it from the pouch. Do not cut it into smaller pieces and do not touch the sticky surface of the patch. Apply the patch to a clean, dry, and intact skin area on your upper, outer arm or upper chest. Choose an area with little or no hair that is free of scars, cuts, or irritation. Avoid putting the patch on skin areas where it could be rubbed off by tight clothing. Press the patch firmly in place with your fingertips to make sure that the edges stick well. The patch should stay in place during showering, bathing, or swimming for a full 7 days. If the patch becomes loose, press the edges against the skin and cover the patch with one of the white adhesive covers that are included in the package. Apply a new patch if the first one becomes too loose or falls off. It is best to apply each patch to a different area of the skin to prevent skin irritation.

To help you remember to use your medicine, try to apply the patch at the same time and on the same day of the week.

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

For transdermal dosage form (patch): For high blood pressure: Adults—One patch applied once every 7 days. Your doctor may adjust your dose as needed. Children—Use and dose must be determined by your doctor.


Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.


Store at room temperature below 30 degrees C (86 degrees F) away from moisture and heat. Throw away any medicine after the expiration date. Keep out of the reach of children.

Side effects

The most common side effects associated with Actinorm are:

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Side effect occurrence does not only depend on medication you are taking, but also on your overall health and other factors.


Avoid being near people who have colds, the flu, or other contagious illnesses. Contact your doctor at once if you develop signs of infection.

Do not receive a "live" vaccine while using Actinorm, or you could develop a serious infection. Live vaccines include measles, mumps, rubella (MMR), polio, rotavirus, typhoid, yellow fever, varicella (chickenpox), zoster (shingles), and nasal flu (influenza) vaccine.

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